Name | Prof. Dr. Peter Chen |
Field | Physikalisch-Organische Chemie |
Address | Professur f. Physik.-Org. Chemie ETH Zürich, HCI G 209 Vladimir-Prelog-Weg 1-5/10 8093 Zürich SWITZERLAND |
Telephone | +41 44 632 28 98 |
peter.chen@org.chem.ethz.ch | |
Department | Chemistry and Applied Biosciences |
Relationship | Full Professor |
Number | Title | ECTS | Hours | Lecturers | |
---|---|---|---|---|---|
529-0243-00L | Reactive Intermediates | 7 credits | 3G | P. Chen | |
Abstract | Advanced physical organic chemistry. Methods for the elucidation of reaction mechanisms. Reactive intermediates. Thermochemistry; isotope labeling; cross-over experiments; kinetic isotope effects; thermodynamics-kinetics correlations; solvation and ion pairs; radical reactions; electron transfer; spectroscopic methods. | ||||
Objective | Methods for the elucidation of organic reaction mechanisms. | ||||
Content | Thermochemistry: homodesmic reactions, estimation with group increments. Non-kinetic methods: product analysis, labeling with stable isotopes, cross-over experiments. Kinetic methods: establishing intermediates, isotope effects. Thermodynamic-kinetic correlations: LFER, Marcus relation. Solvation and ion pairs. | ||||
Lecture notes | A printed script are handed out in the course. This material is also available for download from the web page of the course (as pdf files). | ||||
Literature | Additional reading and original publications are cited in the lectures. | ||||
Prerequisites / Notice | Required level: Courses in organic and physical chemistry of the first and second year. Each participant is expected to contribute to a 30 min. seminar (prepared by groups of 2-4 students), presented in the last weeks of the semester. | ||||
529-0299-00L | Organic Chemistry | 0 credits | 1.5K | J. W. Bode, E. M. Carreira, P. Chen, F. Diederich, P. S. Dittrich, D. Hilvert, H. Wennemers, R. Zenobi | |
Abstract | |||||
Objective |