Yves Barral: Catalogue data in Autumn Semester 2014

Name Prof. Dr. Yves Barral
FieldBiochemie
Address
Institut für Biochemie
ETH Zürich, HPM D 8.3
Otto-Stern-Weg 3
8093 Zürich
SWITZERLAND
Telephone+41 44 632 06 78
Fax+41 44 632 15 91
E-mailyves.barral@bc.biol.ethz.ch
DepartmentBiology
RelationshipFull Professor

NumberTitleECTSHoursLecturers
529-0492-00LCIMST Microscopy & Nanoscopy Seminar1 credit2SY. Barral
AbstractThe seminar series introduces the student to advances in microscopy and nanoscopy with emphasis on light microscopy, electron microscopy, and x-ray microscopy. Both methodological and technological progress as well as applications are discussed.
Objective
551-0103-AALFundamentals of Biology II: Cell Biology Information
Enrolment only for MSc students who need this course as additional requirement.
5 credits11RU. Kutay, Y. Barral, E. Hafen, G. Schertler, U. Suter, S. Werner
AbstractThe goal of this course is to provide students with a wide general understanding in cell biology. With this material as a foundation, students have enough of a cell biological basis to begin their specialization not only in cell biology but also in related fields such as biochemistry, microbiology, pharmacological sciences, molecular biology, and others.
ObjectiveThe goal of this course is to provide students with a wide general understanding cell biology. With this material as a foundation, students have enough of a cell biological basis to begin their specialization not only in cell biology but also in related fields such as biochemistry, microbiology, pharmacological sciences, molecular biology, and others.
ContentThe focus is animal cells and the development of multicellular organisms with a clear emphasis on the molecular basis of cellular structures and phenomena. The topics include biological membranes, the cytoskeleton, protein sorting, energy metabolism, cell cycle and division, viruses, extracellular matrix, cell signaling, embryonic development and cancer research.
LiteratureAlberts et al. ‘Molecular Biology of the Cell’ Fifth edition, 2008 ISBN 978-0-8153-4105-5 (hard cover) and ISBN 978-0-8153-4106-2 (paperback).

Topic/Lecturer/Chapter/Pages: Introduction to Cell Biology/Gebhard Schertler/1+2+3+4/1-193; Cellular compartments/Gebhard Schertler/12/695-748; Membrane lipids/Gebhard Schertler/10/617-629; Working with cells/Ulrike Kutay/9/579-613; Mitochondria/Ulrike Kutay/12+14/695-703/713-723/815-818/856-860; Chloroplasts, peroxisomes/Ulrike Kutay/12+14/695-703/713-723/840-844/856-860; Structure and dynamics of the nucleus/Ulrike Kutay/6+12/362-366/704-706/710-712; Membrane proteins/Gebhard Schertler/10/629-650; Working with membranes/Gebhard Schertler/9/579-615; Nuclear transport of proteins/Ulrike Kutay/12/706-711; RNA processing and nuclear export/Ulrike Kutay/6/345-353/357-366/369; Endoplasmic reticulum/Ulrike Kutay/12/723-745; Vesicular transport/Ulrike Kutay/13/749-766; From the ER through the Golgi/Ulrike Kutay/13/766-779; From the TGN to Lysosomes and the plasma membrane/Ulrike Kutay/13/779-787/799-809; The plasma membrane and endocytosis/Ulrike Kutay/13/787-799; Introduction to the cytoskeleton/Ulrike Kutay/16/965-1035; Microtubules/Ulrike Kutay/16/965-1035; Actin/Muscle/Ulrike Kutay/16/965-1035; Cell polarization and migration/Yves Barral/16/1036-1052; Introduction to the cell cycle/Yves Barral/17/1053-1070; MPF and the cell cycle control machinery/Yves Barral/17/1053-1070; Mechanisms of chromosome segregation/Yves Barral/17/1070-1090; Cell division/Yves Barral/17/1090-1101; Apoptosis/Yves Barral/18/1115-1127; Membrane transport passive and active/Sabine Werner/11/651-667; Ion channels, action potential/Sabine Werner/11/667-687; General principles of signalling/Sabine Werner/15/879-903; Nuclear receptors, G-protein coupled receptors/Sabine Werner/15/879-921; Cell signalling; G-protein coupled receptors/Sabine Werner/15/904-921; Cell signalling; Receptor tyrosine kinases/Sabine Werner/15/921-938; Cell signalling; Tyrosine kinase associated receptors/Sabine Werner/15/921-938; Cell signalling; Receptor serine threonine kinases/Sabine Werner/15/939-944; Signalling through proteolysis/Sabine Werner/15/946-954; Cancer Biology/Sabine Werner/20/1205-1267; Cell-Cell Interactions/Ueli Suter/19/1131-1195; Extracellular Matrix/Ueli Suter/19/1131-1195; Regeneration / Stem Cells/Ueli Suter/23/1417-1484; Germ Cells and Sex Determination/Ernst Hafen/21/1269-1304; Development/Ernst Hafen/22/1305-1417
Prerequisites / Noticenone
551-0103-00LFundamentals of Biology II: Cell Biology Information 5 credits5VU. Kutay, Y. Barral, E. Hafen, G. Schertler, U. Suter, S. Werner
AbstractThe goal of this course is to provide students with a wide general understanding in cell biology. With this material as a foundation, students have enough of a cell biological basis to begin their specialization not only in cell biology but also in related fields such as biochemistry, microbiology, pharmacological sciences, molecular biology, and others.
ObjectiveThe goal of this course is to provide students with a wide general understanding cell biology. With this material as a foundation, students have enough of a cell biological basis to begin their specialization not only in cell biology but also in related fields such as biochemistry, microbiology, pharmacological sciences, molecular biology, and others.
ContentThe focus is animal cells and the development of multicellular organisms with a clear emphasis on the molecular basis of cellular structures and phenomena. The topics include biological membranes, the cytoskeleton, protein sorting, energy metabolism, cell cycle and division, viruses, extracellular matrix, cell signaling, embryonic development and cancer research.
Lecture notesThe lectures are presented in the Powerpoint format. These are available on the WEB for ETH students over the nethz (https://sharepoint.biol.ethz.ch/sites/e-learn/551-0103-00L-H13/default.aspx). Some lectures are available on the ETH WEB site in a live format (Livestream) at the above WEB site.
LiteratureThe lectures follow Alberts et al. ‘Molecular Biology of the Cell’ Fifth edition, 2008 ISBN 978-0-8153-4105-5 (hard cover) and ISBN 978-0-8153-4106-2 (paperback).
Prerequisites / NoticeSome of the lectures are given in the English language.
551-0309-00LConcepts in Modern Genetics Information 6 credits4VY. Barral, D. Bopp, A. Hajnal, O. Voinnet
AbstractConcepts of modern genetics and genomics, including principles of classical genetics; yeast genetics; gene mapping; forward and reverse genetics; structure and function of eukaryotic chromosomes; molecular mechanisms and regulation of transcription, replication, DNA-repair and recombination; analysis of developmental processes; epigenetics and RNA interference.
ObjectiveThis course focuses on the concepts of classical and modern genetics and genomics.
ContentThe topics include principles of classical genetics; yeast genetics; gene mapping; forward and reverse genetics; structure and function of eukaryotic chromosomes; molecular mechanisms and regulation of transcription, replication, DNA-repair and recombination; analysis of developmental processes; epigenetics and RNA interference.
Lecture notesScripts and additional material will be provided during the semester.
Prerequisites / NoticeThis course is a co-production of the University of Zurich and ETH Zurich, and will be taught in English. The course takes place on Monday afternoon at ETH Hoenggerberg, and on Tuesday morning at UniZH Irchel.
551-0336-00LMethods in Cellular Biochemistry Information Restricted registration - show details 6 credits7GP. Picotti, C. M. Azzalin, Y. Barral, B. Kornmann, U. Kutay, V. Panse, M. Peter
AbstractStudents will learn about biochemical approaches to analyze cellular functions. The course consists of practical projects in small groups, lectures and literature discussions. The course concludes with the presentation of results at a poster session.
ObjectiveStudents will learn to design, carry out and assess experiments using current biochemical and cell biological strategies to analyze cellular functions in a wide range of model systems. In particular they will learn novel imaging techniques along with biochemical approaches to understand fundamental cellular pathways. Furthermore, they will learn to assess strengths and limitations of the different approaches and be able to discuss their validity for the analysis of cellular functions.
LiteratureDocumentation and recommended literature (review articles and selected primary literature) will be provided during the course.
Prerequisites / NoticeThis course will be taught in English.
551-0347-00LMolecular Mechanisms of Cell Growth and Polarity Information Restricted registration - show details 6 credits7GR. Kroschewski, Y. Barral, S. Jessberger, M. Peter, A. Wutz
AbstractIntroduction to the principles and molecular mechanisms of cell polarity, using animal cells and fungi as model systems.
ObjectiveThe students learn to describe the principles and molecular mechanisms of cell polarity, using different model systems as examples:
- Animal cells during epithelial and neuronal differentiation
- Fungi during morphogenesis and aging.
Based on lectures, literature reading, discussions, presentations and practical lab work the students will be able to compare experimental strategies in different model systems, and to develop open questions in the field of cell polarity. Students will also know about the mechanisms and consequences of asymmetric cell division such as those performed by stem cells and asymmetric protein functions during morphogenesis and aging.
ContentDuring this Block-Course, the students will learn to
(1) describe and compare the principles and molecular mechanisms of cell polarity in fungi and animal cells,
(2) apply, evaluate and compare experimental strategies in the different model systems, and
(3) select the best model system to answer a particular question.

Students - in groups of 2 or max 3- will be integrated into a research project connected to the subject of the course, within one of the participating research groups.

Lectures and technical notes will be given and informal discussions held to provide you with the theoretical background.
Lecture notesThere will be optional papers to be read before the course start. They serve as framework orientation for the practical parts of this block course and will be made accessible to you shortly before the course starts.
LiteratureDocumentation and recommended literature (review articles) will be provided during the course.
Prerequisites / NoticeThis course will be taught in English and is limited to maximally 15 participants. The first meeting will be on Tuesday, September 16, 2014 in HPM G7 at 13:00 pm.