Yves Barral: Katalogdaten im Frühjahrssemester 2021

NameHerr Prof. Dr. Yves Barral
LehrgebietBiochemie
Adresse
Institut für Biochemie
ETH Zürich, HPM D 8.3
Otto-Stern-Weg 3
8093 Zürich
SWITZERLAND
Telefon+41 44 632 06 78
Fax+41 44 632 15 91
E-Mailyves.barral@bc.biol.ethz.ch
DepartementBiologie
BeziehungOrdentlicher Professor

NummerTitelECTSUmfangDozierende
551-0103-AALFundamentals of Biology II: Cell Biology
Belegung ist NUR erlaubt für MSc Studierende, die diese Lerneinheit als Auflagenfach verfügt haben.

Alle anderen Studierenden (u.a. auch Mobilitätsstudierende, Doktorierende) können diese Lerneinheit NICHT belegen.
5 KP11RU. Kutay, Y. Barral, E. Hafen, G. Schertler, U. Suter, S. Werner
KurzbeschreibungThe goal of this course is to provide students with a wide general understanding in cell biology. With this material as a foundation, students have enough of a cell biological basis to begin their specialization not only in cell biology but also in related fields such as biochemistry, microbiology, pharmacological sciences, molecular biology, and others.
LernzielThe goal of this course is to provide students with a wide general understanding cell biology. With this material as a foundation, students have enough of a cell biological basis to begin their specialization not only in cell biology but also in related fields such as biochemistry, microbiology, pharmacological sciences, molecular biology, and others.
InhaltThe focus is animal cells and the development of multicellular organisms with a clear emphasis on the molecular basis of cellular structures and phenomena. The topics include biological membranes, the cytoskeleton, protein sorting, energy metabolism, cell cycle and division, viruses, extracellular matrix, cell signaling, embryonic development and cancer research.
LiteraturAlberts et al. 'Molecular Biology of the Cell' 6th edition, 2014, ISBN 9780815344322 (hard cover) and ISBN 9780815345244 (paperback).

Topic/Lecturer/Chapter/Pages:

Analyzing cells & molecules / Gebhard Schertler/8/ 439-463;
Membrane structure / Gebhard Schertler/ 10/ 565-595;
Compartments and Sorting/ Ulrike Kutay/12+14+6/641-694/755-758/782-783/315-320/325 -333/Table 6-2/Figure6-20, 6-21, 6-32, 6-34;
Intracellular Membrane Traffic/ Ulrike Kutay/13/695-752;
The Cytoskeleton/ Ulrike Kutay/ 16/889 - 948 (only the essentials);
Membrane Transport of Small Molecules and the Electrical Properties of Membranes /Sabine Werner/11/597 - 633;
Mechanisms of Cell Communication / Sabine Werner/15/813-876;
Cancer/ Sabine Werner/20/1091-1141;
Cell Junctions and Extracellular Matrix/Ueli Suter / 1035-1081;
Stem Cells and Tissue Renewal/Ueli Suter /1217-1262;
Development of Multicellular organisms/ Ernst Hafen/ 21/ 1145-1179 /1184-1198/1198-1213;
Cell Migration/Joao Matos/951-960;
Cell Death/Joao Matos/1021-1032;
Cell Cycle/chromosome segregation/Cell division/Meiosis/Joao Matos/ 963-1018.
Voraussetzungen / Besonderesnone
551-0126-00LGrundlagen der Biologie II: Zellen Information 6 KP5GK. Weis, F. Allain, Y. Barral, W.‑D. Hardt, U. Kutay, M. Peter, I. Zemp
KurzbeschreibungDie Vorlesung vermittelt eine Einführung in die Funktion und Regulation von Zellen.
LernzielEinführung in die Funktion und Regulation von Zellen
InhaltDie Lehrveranstaltung vermittelt ein grundlegendes Verständnis von der Struktur, Organisation, Funktion und Regulation der Zelle. Die Vorlesung ist in zwei Hauptteile gegliedert:
Teil 1: Zellbiologie der Prokaryonten, Evolution, Populationen
Dieser Abschnitt erläutert die generellen Prinzipien des Aufbaus und der Regulation von prokaryontischen Zellen, und erklärt die Genetik und Evolution von Bakterien.
Teil II: Vereinheitlichende Konzepte in Eukarya
Dieser Vorlesungsteil gibt eine breite Einführung in die generelle Struktur von eukaryontischer Zellen, und vermittelt wichtige Konzepte, die den intrazelluläre Aufbau und Transport und der Regulation der Genexpression in Eukaryonten betreffen.
SkriptDie neu konzipierte Vorlesung wird durch Skripte unterstützt.
LiteraturDie Vorlesung wird durch Skripte unterstützt. Ausserdem kann das Lehrbuch "Molecular Biology of the Cell", Alberts et al. 6th edition, Taylor und Francis, und "Brock Biology of Microorganisms", Madigan et al. 15th edition, Pearson, als Unterstützung für den Vortrag verwendet werden. "
551-0320-00LCellular Biochemistry (Part II)3 KP2VY. Barral, R. Kroschewski, A. E. Smith
KurzbeschreibungThis course will focus on molecular mechanisms and concepts underlying cellular biochemistry, providing advanced insights into the structural and functional details of individual cell components, and the complex regulation of their interactions. Particular emphasis will be on the spatial and temporal integration of different molecules and signaling pathways into global cellular processes.
LernzielThe full-year course (551-0319-00 & 551-0320-00) focuses on the molecular mechanisms and concepts underlying the biochemistry of cellular physiology, investigating how these processes are integrated to carry out highly coordinated cellular functions. The molecular characterization of complex cellular functions requires a combination of approaches such as biochemistry, but also cell biology and genetics. This course is therefore the occasion to discuss these techniques and their integration in modern cellular biochemistry.
The students will be able to describe the structural and functional details of individual cell components, and the spatial and temporal regulation of their interactions. In particular, they will learn to explain how different molecules and signaling pathways can be integrated during complex and highly dynamic cellular processes such as intracellular transport, cytoskeletal rearrangements, cell motility, and cell division. In addition, they will be able to illustrate the relevance of particular signaling pathways for cellular pathologies such as cancer or during cellular infection.
InhaltSpatial and temporal integration of different molecules and signaling pathways into global cellular processes, such as cell division, cell infection and cell motility. Emphasis is also put on the understanding of pathologies associated with defective cell physiology, such as cancer or during cellular infection.
LiteraturRecommended supplementary literature may be provided during the course.
Voraussetzungen / BesonderesTo attend this course the students must have a solid basic knowledge in chemistry, biochemistry, cell biology and general biology. Biology students have in general already attended the first part of the "Cellular Biochemistry" concept course (551-0319-00). The course will be taught in English.
In addition, the course will be based on a blended-learning scenario, where frontal lectures will be complemented with carefully chosen web-based teaching elements that students access through the ETH Moodle platform.
551-0339-00LMolecular Mechanisms of Cell Dynamics Belegung eingeschränkt - Details anzeigen
Number of participants limited to 18.

The enrolment is done by the D-BIOL study administration.

General safety regulations for all block courses:
-Whenever possible the distance rules have to be respected
-All students have to wear masks throughout the course. Please keep reserve masks ready. Surgical masks (IIR) or medical grade masks (FFP2) without a valve are permitted. Community masks (fabric masks) are not allowed.
-The installation and activation of the Swiss Covid-App is highly encouraged
-Any additional rules for individual courses have to be respected
-Students showing any COVID-19 symptoms are not allowed to enter ETH buildings and have to inform the course responsible
6 KP7PE. Dultz, Y. Barral, U. Kutay, M. Peter, K. Weis
KurzbeschreibungApplication of current experimental strategies to study the dynamics of complex and highly regulated cellular processes.
LernzielIn this course, students will
- learn what principles govern cellular dynamics and how these are regulated.
- learn to evaluate and to apply current strategies to study the dynamics of complex and highly regulated cellular processes
InhaltDuring this Block-Course, the students will learn to
(1) describe the important mechanisms and regulators of dynamic processes in cells,
(2) perform experimental techniques to quantify dynamic cellular processes,
(3) evaluate and compare experimental strategies and model systems,
(4) formulate and present scientific concepts in an oral presentation.

Topics discussed will include
- mobility in the cell (passive and active)
- compartmentalization (by membranes and via phase separation)
- examples of cell biological processes dependent on mobility and compartmentalization.

Students will work in small groups in individual labs on one research project (8 full days of practical work; every group of students will stay in the same lab during the entire course). The projects are close to the actual research carried out in the participating research groups, but with a clear connection to the subject of the course.
LiteraturDocumentation and recommended literature (review articles and selected primary literature) will be provided during the course.
Voraussetzungen / BesonderesThis course will be taught in english.
551-1300-00LCause and Consequences of Unstable Genomes Belegung eingeschränkt - Details anzeigen
Number of participants limited to 14.

The enrolment is done by the D-BIOL study administration.

General safety regulations for all block courses:
-Whenever possible the distance rules have to be respected
-All students have to wear masks throughout the course. Please keep reserve masks ready. Surgical masks (IIR) or medical grade masks (FFP2) without a valve are permitted. Community masks (fabric masks) are not allowed.
-The installation and activation of the Swiss Covid-App is highly encouraged
-Any additional rules for individual courses have to be respected
-Students showing any COVID-19 symptoms are not allowed to enter ETH buildings and have to inform the course responsible
6 KP7PM. Jagannathan, Y. Barral, C. Beyer, K. Bomblies, R. Kroschewski, G. Neurohr
KurzbeschreibungThe course will introduce students to key concepts and laboratory research within the broad field of "Genome stability".
LernzielStudents will learn to design, apply and evaluate current research strategies in a wide range of modern research areas encompassing the broad field of "Genome stability".
InhaltThe course will consist of lectures, practical laboratory work in small groups, informal progress report sessions, and the presentation of laboratory work. Lectures will expose students to key concepts and techniques in the field. Students will team into small groups and work in one laboratory for the duration of the course. Students will meet regularly for informal "progress report" discussions of their projects. Student performance will be assessed based on the quality of their practical work, a written exam on frontal lecture material, and a presentation of their practical work.
LiteraturDocumentation and recommended literature in the form of review articles and selected primary literature will be provided during the course.
Voraussetzungen / BesonderesThis course will be taught in English.