Matthias Peter: Katalogdaten im Frühjahrssemester 2012 |
Name | Herr Prof. Dr. Matthias Peter |
Lehrgebiet | Biochemie |
Adresse | Institut für Biochemie ETH Zürich, HPM G 8.1 Otto-Stern-Weg 3 8093 Zürich SWITZERLAND |
Telefon | +41 44 633 65 86 |
Fax | +41 44 633 12 28 |
matthias.peter@bc.biol.ethz.ch | |
Departement | Biologie |
Beziehung | Ordentlicher Professor |
Nummer | Titel | ECTS | Umfang | Dozierende | |
---|---|---|---|---|---|
551-0102-AAL | Fundamentals of Biology IB: Molecular Biology and Biochemistry Die Lerneinheit kann nur von MSc Studierenden mit Zulassungsauflagen belegt werden. | 5 KP | 11R | R. Glockshuber, N. Ban, D. Hilvert, K. Locher, M. Peter | |
Kurzbeschreibung | Amino acids; structure of proteins; folding; dynamics and evolution; protein purification; sugars and polysaccharides; lipids and membranes. Enzymatic catalysis. Metabolism; Gene expression and propagation of genetic information; structure of DNA; transcription; protein biosynthesis; DNA replication. Gene technology; production of recombinant proteins. | ||||
Lernziel | Knowledge on the structural construction of biological macromolecules, principles of enyme catalysed reactions, basics of molecular genetics and protein biochemistry, basic mechanisms of metabolism and of DNA replication and gene expression. | ||||
Inhalt | Part 1: Biomolecules; amino acids; covalent assembly of proteins; three dimensional structure of proteins; folding; dynamics and evolution of proteins; methods of protein purification; sugars and polysaccharides; lipids and membranes. Part 2: Enzymatic catalysis: classes of enzymes; kinetics of non catalysed versus catalysed reactions. Examples for the mechanisms of enzyme catalysis. Part 3: Metabolism: Principles of metabolic pathways in living cells; glycolysis; glycogen metabolism; mechanisms of membrane transport; citric acid cycle; electron transport and oxidative phosphorylation. Part 4: Gene expression and propagation of genetic information; structure of DNA; DNA modifying enzymes and manupulation of nucleic acids; transcription; protein biosynthesis; DNA replication. Part 5: Gene technology; production of recombinant proteins | ||||
Literatur | "Biochemistry" (Voet & Voet; Wiley & Sons, 2nd edition). | ||||
551-0102-00L | GL der Biologie IB: Molekularbiologie und Biochemie | 5 KP | 5V | R. Glockshuber, N. Ban, D. Hilvert, K. Locher, M. Peter | |
Kurzbeschreibung | Aminosäuren; Struktur von Proteinen; Faltung, Dynamik und Evolution ; Proteinreinigung; Zucker und Polysaccharide; Lipide und Membranen. Enzymatische Katalyse. Stoffwechsel; Genexpression und Weitergabe der Erbinformation: Struktur von DNA; Transkription; Proteinbiosynthese; DNA-Replikation. Gentechnologie: Produktion rekombinanter Proteine. | ||||
Lernziel | Kenntnis von strukturellem Aufbau biologischer Makromoleküle, Prinzipien enzymatisch katalysierter Reaktionen, Grundlagen der Molekulargenetik und Proteinbiochemie, grundlegenden Stoffwechselreaktionen und Mechanismen der DNA Replikation und Genexpression. | ||||
Inhalt | Teil 1: Biomoleküle: Aminosäuren; kovalente Struktur von Proteinen; dreidimensionale Struktur von Proteinen; Faltung, Dynamik und Evolution von Proteinen; Methoden der Proteinreinigung; Zucker und Polysaccharide; Lipide und Membranen. Teil 2: Enzymatische Katalyse: Enzymklassen, Kinetik unkatalysierter und katalysierter Stoffwechselreaktionen, Beispiele für Mechanismen enzymatischer Katalyse. Teil 3: Stoffwechsel: Grundprinzipien von Stoffwechselvorgängen in lebenden Zellen; Glykolyse; Glykogenstoffwechsel; Membrantransportprozesse; Citratzyklus; Elektronentransport und oxidative Phosphorylierung. Teil 4: Genexpression und Weitergabe der Erbinformation: Struktur von DNA; DNA-modifizierende Enzyme und Manipulation von Nukleinsäuren; Transkription; Proteinbiosynthese; DNA-Replikation. Teil 5: Gentechnologie: Produktion rekombinanter Proteine. | ||||
Skript | Teilweise vorhanden. Siehe z.B. unter www.micro.biol.ethz.ch | ||||
Literatur | "Biochemistry" (Voet & Voet; Wiley & Sons, 2nd edition). | ||||
551-0339-00L | Molecular Mechanisms of Cell Division | 6 KP | 7G | P. Meraldi, Y. Barral, M. de Medina Redondo, U. Kutay, M. Peter | |
Kurzbeschreibung | Application of the current strategies to study complex and highly regulated cellular processes such as cell division. | ||||
Lernziel | The students learn to evaluate and to apply the current strategies to study complex and highly regulated cellular precesses such as cell division. | ||||
Inhalt | During this Block-Course, the students will learn to (1) describe the main regulators and the mechanics of cell division and growth, (2) perform standard lab techniques and quantitate mitosis, (3) evaluate and compare experimental strategies and model systems, (4) independently search and critically evaluate scientific literature on a specific problem and present it in a seminar, and (5) formulate scientific concepts (preparation and presentation of a poster). Students will work in small groups in individual labs on one research project (8 full days of practical work; every group of students will stay in the same lab during the entire course). The projects are close to the actual research carried out in the participating research groups, but with a clear connection to the subject of the course. | ||||
Literatur | Documentation and recommended literature (review articles and selected primary literature) will be provided during the course. | ||||
Voraussetzungen / Besonderes | This course will be taught in english. | ||||
551-1310-00L | A Problem-Based Approach to Cellular Biochemistry | 4 KP | 2G | M. Peter, A. Helenius, B. Kornmann, P. Meraldi, V. Panse, P. Picotti, A. E. Smith | |
Kurzbeschreibung | Independent, guided acquisition of an overview over a defined area of research, identification of important open questions, development of an experimental strategy to address a defined question, and formulation of this strategy within the framework of a research grant. | ||||
Lernziel | The students will learn to acquire independently an overview over a defined area of research, and to identify important open questions. In addition, they will learn to develop an experimental strategy to address a defined question, and to formulate this strategy within the framework of a research grant. | ||||
Inhalt | The students will work in groups of two to three, in close contact with a tutor (a group leader from the Institute of Biochemistry). The overview and the small research grant will be developed independently by the students, with guidance from the tutor (regular meetings are mandatory). The students will write up both the overview and the grant in short reports, and present them to their colleagues. | ||||
Literatur | The identification of appropriate literature is a component of the course. | ||||
Voraussetzungen / Besonderes | This course will be taught in english, and requires extensive independent work. | ||||
551-1316-00L | CIMST Interdisciplinary Summer School on Bio-Medical Imaging | 3 KP | 6G | R. Kroschewski, S. M. Ametamey, Y. Barral, G. Csúcs, F. Helmchen, P. Horvath, T. Ishikawa, B. Kornmann, P. Koumoutsakos, S. Kozerke, M. Peter, M. Rudin, R. Schibli, B. Schuler, M. Stampanoni, G. Székely, R. A. Wepf, M. P. Wolf | |
Kurzbeschreibung | The school will discuss recent progress and current challenges in biological and medical imaging. Topics include computer aided image analysis and modeling. The students will have theoretical training in the form of lectures and practical sessions (either hands-on lab work or lab demonstrations). | ||||
Lernziel | The students know about the possibilities and limitations of a wide range of modern imaging methods and can propose suitable methods for a given imaging problem. | ||||
Inhalt | The CIMST (Center for Imaging Science and Technology, a Competence Center of ETH Zurich) summer school discusses recent progress and current challenges in biological and medical imaging. The students will have theoretical training in the form of lectures and practical sessions (either hands-on lab work or lab demonstrations). A specialization on medical or biological imaging will be offered. Some lectures will be given in parallel for life scientists and physical scientists. Cutting edge techniques using a wide range of imaging mechanisms such as magnetic resonance, positron emission, infrared and optical microscopy, electron microscopy and x-ray imaging will be put in the context of selected biomedical problems. In particular, multimodal and multiscale imaging methods as well as supporting technologies such as computer aided imaging analysis and modeling will be discussed. The school aims to point out possibilities of the integration of different imaging methods. | ||||
Skript | None | ||||
Voraussetzungen / Besonderes | We plan to admit about 50 Master or PhD students with background in either biology, chemistry, mathematics, physics, computer or medical science or engineering (Zürich area and from abroad). The school will be taught in English. Admission will be given via a selection process based on the curriculum vitae, a statement of purpose. For details of the program and the application procedure please consult http://www.cimst.ethz.ch/education/summer_school/12. The application deadline is May 28, 2012. A decision on whether your application is accepted or not will be given in June 2012. Only after a positive decision is received, you may sign in via my-studies in the course. |