Sven Panke: Katalogdaten im Herbstsemester 2016

NameHerr Prof. Dr. Sven Panke
Bioverfahrenstechnik, Panke
ETH Zürich, BSA M 740
Mattenstr. 26
4058 Basel
Telefon+41 61 387 32 09
BeziehungOrdentlicher Professor

626-0007-AALMicrobial Biotechnology
Belegung ist NUR erlaubt für MSc Studierende, die diese Lerneinheit als Auflagenfach verfügt haben.

Alle anderen Studierenden (u.a. auch Mobilitätsstudierende, Doktorierende) können diese Lerneinheit NICHT belegen.
4 KP9RS. Panke
KurzbeschreibungIntroduction into the field of microbial biotechnology, covering possible products of enzyme and fermentation technology.
LernzielThe student should be able to identify opportunities for microbial bioprocesses and to go through basic and advanced design procedures for microbial bioprocesses.
InhaltBioprocess development - An interdisciplinary challenge
Introduction to engineering calculations
Presentation and analysis of data
Material balances
Energy balances
Unsteady-state material and energy balances
Fluid flow
Mass transfer
Homogeneous rearctions
Heterogeneous reactions
Reactor engineering
LiteraturPauline Doran, Bioprocess Engineering Principles, edition 2013, chapters
1 to 8, 10, 12-14

Other literature:
Nielsen/Villadsen, Bioreaction Engineering Principles (Kluwer)
van´t Riet/Tramper: Basic bioreactor design
Stephanopoulos/Aristidou/Nielsen: Metabolic Engineering
Voraussetzungen / BesonderesThere will be two opportunities for tutorials during the semester.
636-0001-00LSeparations in Biotechnology and Bioprocess Economy6 KP3GS. Panke
KurzbeschreibungSeparations play an integral part of any biotechnological process. This course aims at enabling students specifically with a chemistry/biology background to select & roughly design suitable separation processes for typical biotechnological products such as monoclonal antibodies, antibiotics, and fine chemicals and at providing a basic set of purification operations & judge on process economy.
LernzielStudents should be able to select for a given biotechnological product a suitable set of purification operations and judge on process economy.
InhaltIntroduction – membrane operations – adsorption and chromatography – crystallization – overall process economics –
SkriptHandouts during course
636-0301-00LCurrent Topics in Biosystems Science and Engineering2 KP1ST. Stadler, N. Beerenwinkel, Y. Benenson, K. M. Borgwardt, P. S. Dittrich, M. Fussenegger, A. Hierlemann, D. Iber, M. H. Khammash, D. J. Müller, S. Panke, P. Pantazis, R. Paro, R. Platt, S. Reddy, T. Schroeder, J. Stelling
KurzbeschreibungThis seminar will feature invited lectures about recent advances and developments in systems biology, including topics from biology, bioengineering, and computational biology.
LernzielTo provide an overview of current systems biology research.
InhaltThe final list of topics will be available at
636-0507-00LSynthetic Biology II Belegung eingeschränkt - Details anzeigen 4 KP4AS. Panke, Y. Benenson, J. Stelling
Kurzbeschreibung7 months biological design project, during which the students are required to give presentations on advanced topics in synthetic biology (specifically genetic circuit design) and then select their own biological system to design. The system is subsequently modeled, analyzed, and experimentally implemented. Results are presented at an international student competition at the MIT (Cambridge).
LernzielThe students are supposed to acquire a deep understanding of the process of biological design including model representation of a biological system, its thorough analysis, and the subsequent experimental implementation of the system and the related problems.
InhaltPresentations on advanced synthetic biology topics (eg genetic circuit design, adaptation of systems dynamics, analytical concepts, large scale de novo DNA synthesis), project selection, modeling of selected biological system, design space exploration, sensitivity analysis, conversion into DNA sequence, (DNA synthesis external,) implementation and analysis of design, summary of results in form of scientific presentation and poster, presentation of results at the iGEM international student competition (
SkriptHandouts during course
Voraussetzungen / BesonderesThe final presentation of the project is typically at the MIT (Cambridge, US). Other competing schools include regularly Imperial College, Cambridge University, Harvard University, UC Berkeley, Princeton Universtiy, CalTech, etc.

This project takes place between end of Spring Semester and beginning of Autumn Semester. Registration in April.

Please note that the number of ECTS credits and the actual work load are disconnected.