Marcy Zenobi-Wong: Katalogdaten im Frühjahrssemester 2021

NameFrau Prof. Dr. Marcy Zenobi-Wong
LehrgebietKnorpeltechnologie und -regeneration
Adresse
Gewebetechnol. und Biofabrikation
ETH Zürich, HPL J 22
Otto-Stern-Weg 7
8093 Zürich
SWITZERLAND
Telefon+41 44 632 50 89
E-Mailmarcy.zenobi@hest.ethz.ch
DepartementGesundheitswissenschaften und Technologie
BeziehungOrdentliche Professorin

NummerTitelECTSUmfangDozierende
376-0008-00LVertiefung Physiologie und Pathophysiologie Belegung eingeschränkt - Details anzeigen
Nur für Gesundheitswissenschaften und Technologie BSc.
4 KP4VK. De Bock, O. Bar-Nur, M. Detmar, G. A. Kuhn, M. Ristow, G. Schratt, C. Spengler, C. Wolfrum, M. Zenobi-Wong
KurzbeschreibungVertiefende Theorie zu molekularen und pathophysiologischen Aspekten von Nerven, Muskeln, Herz, Kreislauf, Atmung und Sinnesorganen.
LernzielVertiefendes Wissen über Anatomie und Physiologie.
InhaltMolekulare Grundlagen von physiologischen Prozessen, Prozesse der Krankheitsentwicklung.
Voraussetzungen / BesonderesDer Kurs wird in Deutsch und Englisch gehalten
376-1614-00LPrinciples in Tissue Engineering3 KP2VK. Maniura, M. Rottmar, M. Zenobi-Wong
KurzbeschreibungFundamentals in blood coagulation; thrombosis, blood rheology, immune system, inflammation, foreign body reaction on the molecular level and the entire body are discussed. Applications of biomaterials for tissue engineering in different tissues are introduced. Fundamentals in medical implantology, in situ drug release, cell transplantation and stem cell biology are discussed.
LernzielUnderstanding of molecular aspects for the application of biodegradable and biocompatible Materials. Fundamentals of tissue reactions (eg. immune responses) against implants and possible clinical consequences will be discussed.
InhaltThis class continues with applications of biomaterials and devices introduced in Biocompatible Materials I. Fundamentals in blood coagulation; thrombosis, blood rheology; immune system, inflammation, foreign body reaction on the level of the entire body and on the molecular level are introduced. Applications of biomaterials for tissue engineering in the vascular system, skeletal muscle, heart muscle, tendons and ligaments, bone, teeth, nerve and brain, and drug delivery systems are introduced. Fundamentals in medical implantology, in situ drug release, cell transplantation and stem cell biology are discussed.
SkriptHandouts provided during the classes and references therin.
LiteraturThe molecular Biology of the Cell, Alberts et al., 5th Edition, 2009.
Principles in Tissue Engineering, Langer et al., 2nd Edition, 2002
376-1624-00LPractical Methods in Biofabrication Belegung eingeschränkt - Details anzeigen
Number of participants limited to 12.
5 KP4PM. Zenobi-Wong, S. J. Ferguson, S. Schürle-Finke
KurzbeschreibungBiofabrication involves the assembly of materials, cells, and biological building blocks into grafts for tissue engineering and in vitro models. The student learns techniques involving the fabrication and characterization of tissue engineered scaffolds and the design of 3D models based on medical imaging data. They apply this knowledge to design, manufacture and evaluate a biofabricated graft.
LernzielThe objective of this course is to give students hands-on experience with the tools required to fabricate tissue engineered grafts. During the first part of this course, students will gain practical knowledge in hydrogel synthesis and characterization, fuse deposition modelling and stereolithography, bioprinting and bioink design, electrospinning, and cell culture and viability testing. They will also learn the properties of common biocompatible materials used in fabrication and how to select materials based on the application requirements. The students learn principles for design of 3D models. Finally the students will apply their knowledge to a problem-based Project in the second half of the Semester. The Project requires significant time outside of class Hours, strong commitment and ability to work independently.
Voraussetzungen / BesonderesNot recommended if passed 376-1622-00 Practical Methods in Tissue Engineering
376-1714-AALBiocompatible Materials
Belegung ist NUR erlaubt für MSc Studierende, die diese Lerneinheit als Auflagenfach verfügt haben.

Alle anderen Studierenden (u.a. auch Mobilitätsstudierende, Doktorierende) können diese Lerneinheit NICHT belegen.
4 KP9RK. Maniura, M. Zenobi-Wong
KurzbeschreibungIntroduction to molecules used for biomaterials, molecular interactions between different materials and biological systems (molecules, cells, tissues). The concept of biocompatibility is discussed and important techniques from biomaterials research and development are introduced.
LernzielThe course covers the follwing topics:
1. Introdcution into molecular characteristics of molecules involved in the materials-to-biology interface. Molecular design of biomaterials.
2. The concept of biocompatibility.
3. Introduction into methodology used in biomaterials research and application.
4. Introduction to different material classes in use for medical applications.
InhaltIntroduction into natural and polymeric biomaterials used for medical applications. The concepts of biocompatibility, biodegradation and the consequences of degradation products are discussed on the molecular level. Different classes of materials with respect to potential applications in tissue engineering, drug delivery and for medical devices are introduced. Strong focus lies on the molecular interactions between materials having very different bulk and/or surface chemistry with living cells, tissues and organs. In particular the interface between the materials surfaces and the eukaryotic cell surface and possible reactions of the cells with an implant material are elucidated. Techniques to design, produce and characterize materials in vitro as well as in vivo analysis of implanted and explanted materials are discussed.
A link between academic research and industrial entrepreneurship is demonstrated by external guest speakers, who present their current research topics.
SkriptHandouts are deposited online (moodle).
LiteraturLiterature:
- Biomaterials Science: An Introduction to Materials in Medicine, Ratner B.D. et al, 3rd Edition, 2013
- Comprehensive Biomaterials, Ducheyne P. et al., 1st Edition, 2011

(available online via ETH library)

Handouts and references therin.
376-1974-00LColloquium in Biomechanics Information 2 KP2KB. Helgason, S. J. Ferguson, R. Müller, J. G. Snedeker, B. Taylor, M. Zenobi-Wong
KurzbeschreibungCurrent topics in biomechanics presented by speakers from academia and industry.
LernzielGetting insight into actual areas and problems of biomechanics.