Ernst Hafen: Catalogue data in Autumn Semester 2016 |
Name | Prof. em. Dr. Ernst Hafen |
Field | Molekulare Entwicklungsbiologie |
Address | Inst. f. Molekulare Systembiologie ETH Zürich, HPM H 29 Otto-Stern-Weg 3 8093 Zürich SWITZERLAND |
hafen@imsb.biol.ethz.ch | |
URL | http://www.imsb.ethz.ch/researchgroup/hafene |
Department | Biology |
Relationship | Professor emeritus |
Number | Title | ECTS | Hours | Lecturers | |
---|---|---|---|---|---|
551-0015-00L | Biology I | 2 credits | 2V | R. Glockshuber, E. Hafen | |
Abstract | The lecture Biology I, together with the lecture Biology II in the following summer semester, is a basic, introductory course into Biology for Students of Materials Sciences and other students with biology as subsidiary subject. | ||||
Objective | The goal of this course is to give the students a basic understanding of the molecules that build a cell and make it function, and the basic principles of metabolism and molecular genetics. | ||||
Content | Die folgenden Kapitelnummern beziehen sich auf das der Vorlesung zugrundeliegende Lehrbuch "Biology" (Campbell & Rees, 10th edition, 2015) Kapitel 1-4 des Lehrbuchs werden als Grundwissen vorausgesetzt 1. Aufbau der Zelle Kapitel 5: Struktur und Funktion biologischer Makromoleküle Kapitel 6: Eine Tour durch die Zelle Kaptiel 7: Membranstruktur und-funktion Kapitel 8: Einführung in den Stoffwechsel Kapitel 9: Zelluläre Atmung und Speicherung chemischer Energie Kapitel 10: Photosynthese Kapitel 12: Der Zellzyklus Kapitel 17: Vom Gen zum Protein 2. Allgemeine Genetik Kapitel 13: Meiose und Reproduktionszyklen Kapitel 14: Mendel'sche Genetik Kapitel 15: Die chromosomale Basis der Vererbung Kapitel 16: Die molekulare Grundlage der Vererbung Kapitel 18: Genetik von Bakterien und Viren Kapitel 46: Tierische Reproduktion Grundlagen des Stoffwechsels und eines Überblicks über molekulare Genetik | ||||
Lecture notes | Der Vorlesungsstoff ist sehr nahe am Lehrbuch gehalten, Skripte werden ggf. durch die Dozenten zur Verfügung gestellt. | ||||
Literature | Das folgende Lehrbuch ist Grundlage für die Vorlesungen Biologie I und II: „Biology“, Campbell and Rees, 10th Edition, 2015, Pearson/Benjamin Cummings, ISBN 978-3-8632-6725-4 | ||||
Prerequisites / Notice | Zur Vorlesung Biologie I gibt es während der Prüfungssessionen eine einstündige, schriftliche Prüfung. Die Vorlesung Biologie II wird separat geprüft. | ||||
551-0016-AAL | Biology II Enrolment ONLY for MSc students with a decree declaring this course unit as an additional admission requirement. Any other students (e.g. incoming exchange students, doctoral students) CANNOT enrol for this course unit. | 2 credits | 4R | M. Stoffel, E. Hafen | |
Abstract | The lecture course Biology II is a basic introductory course into biology for students who need to pass this course for admission to their MSc curriculum. | ||||
Objective | The objective of the lecture course Biology II is the understanding of form, function, and development of animals and of the basic underlying mechanisms. | ||||
Content | The following numbers of chapters refer to the text-book "Biology" (Campbell & Reece, 7th edition, 2005) on which the course is based. Chapters 1-4 are a basic prerequisite. The sections "Structure of the Cell" (Chapters 5-10, 12, 17) and "General Genetics" (Chapters 13-16, 18, 46) are covered by the lecture Biology I. 1. Genomes, DNA Technology, Genetic Basis of Development Chapter 19: Eukaryotic Genomes: Organization, Regulation, and Evolution Chapter 20: DNA Technology and Genomics Chapter 21: The Genetic Basis of Development 2. Form, Function, and Development of Animals I Chapter 40: Basic Principles of Animal Form and Function Chapter 41: Animal Nutrition Chapter 44: Osmoregulation and Excretion Chapter 47: Animal Development 3. Form, Function, and Develeopment of Animals II Chapter 42: Circulation and Gas Exchange Chapter 43: The Immune System Chapter 45: Hormones and the Endocrine System Chapter 48: Nervous Systems Chapter 49: Sensory and Motor Mechanisms | ||||
Literature | The following text-book is the basis for the courses Biology I and II: „Biology“, Campbell and Reece, 7th Edition, 2005, Pearson/Benjamin Cummings, ISBN 0-8053-7166-4 | ||||
Prerequisites / Notice | Prerequisite: Lecture course Biology I of winter semester | ||||
551-0103-AAL | Fundamentals of Biology II: Cell Biology Enrolment ONLY for MSc students with a decree declaring this course unit as an additional admission requirement. Any other students (e.g. incoming exchange students, doctoral students) CANNOT enrol for this course unit. | 5 credits | 11R | E. Hafen, J. Fernandes de Matos, U. Kutay, G. Schertler, U. Suter, S. Werner | |
Abstract | The goal of this course is to provide students with a wide general understanding in cell biology. With this material as a foundation, students have enough of a cell biological basis to begin their specialization not only in cell biology but also in related fields such as biochemistry, microbiology, pharmacological sciences, molecular biology, and others. | ||||
Objective | The goal of this course is to provide students with a wide general understanding cell biology. With this material as a foundation, students have enough of a cell biological basis to begin their specialization not only in cell biology but also in related fields such as biochemistry, microbiology, pharmacological sciences, molecular biology, and others. | ||||
Content | The focus is animal cells and the development of multicellular organisms with a clear emphasis on the molecular basis of cellular structures and phenomena. The topics include biological membranes, the cytoskeleton, protein sorting, energy metabolism, cell cycle and division, viruses, extracellular matrix, cell signaling, embryonic development and cancer research. | ||||
Literature | Alberts et al. 'Molecular Biology of the Cell' 6th edition, 2014, ISBN 9780815344322 (hard cover) and ISBN 9780815345244 (paperback). Topic/Lecturer/Chapter/Pages: Analyzing cells & molecules / Gebhard Schertler/8/ 439-463; Membrane structure / Gebhard Schertler/ 10/ 565-595; Compartments and Sorting/ Ulrike Kutay/12+14+6/641-694/755-758/782-783/315-320/325 -333/Table 6-2/Figure6-20, 6-21, 6-32, 6-34; Intracellular Membrane Traffic/ Ulrike Kutay/13/695-752; The Cytoskeleton/ Ulrike Kutay/ 16/889 - 948 (only the essentials); Membrane Transport of Small Molecules and the Electrical Properties of Membranes /Sabine Werner/11/597 - 633; Mechanisms of Cell Communication / Sabine Werner/15/813-876; Cancer/ Sabine Werner/20/1091-1141; Cell Junctions and Extracellular Matrix/Ueli Suter / 1035-1081; Stem Cells and Tissue Renewal/Ueli Suter /1217-1262; Development of Multicellular organisms/ Ernst Hafen/ 21/ 1145-1179 /1184-1198/1198-1213; Cell Migration/Joao Matos/951-960; Cell Death/Joao Matos/1021-1032; Cell Cycle/chromosome segregation/Cell division/Meiosis/Joao Matos/ 963-1018. | ||||
Prerequisites / Notice | none | ||||
551-0103-00L | Fundamentals of Biology II: Cell Biology | 5 credits | 5V | E. Hafen, J. Fernandes de Matos, U. Kutay, G. Schertler, U. Suter, S. Werner | |
Abstract | The goal of this course is to provide students with a wide general understanding in cell biology. With this material as a foundation, students have enough of a cell biological basis to begin their specialization not only in cell biology but also in related fields such as biochemistry, microbiology, pharmacological sciences, molecular biology, and others. | ||||
Objective | The goal of this course is to provide students with a wide general understanding cell biology. With this material as a foundation, students have enough of a cell biological basis to begin their specialization not only in cell biology but also in related fields such as biochemistry, microbiology, pharmacological sciences, molecular biology, and others. | ||||
Content | The focus is animal cells and the development of multicellular organisms with a clear emphasis on the molecular basis of cellular structures and phenomena. The topics include biological membranes, the cytoskeleton, protein sorting, energy metabolism, cell cycle and division, viruses, extracellular matrix, cell signaling, embryonic development and cancer research. | ||||
Lecture notes | The lectures are presented in the Powerpoint format. These are available on the WEB for ETH students over the nethz (Moodle). Some lectures are available on the ETH WEB site in a live format (Livestream) at the above WEB site. | ||||
Literature | The lectures follow Alberts et al. `Molecular Biology of the Cell' 6th edition, 2014, ISBN 9780815344322 (hard cover) and ISBN 9780815345244 (paperback). | ||||
Prerequisites / Notice | Some of the lectures are given in the English language. Certain sections of the text-book must be studied by self-instruction. | ||||
551-0105-00L | Fundamentals of Biology IA | 5 credits | 5G | M. Aebi, E. Hafen | |
Abstract | The course provides an introduction to the basics of molecular- and cell biology and genetics. | ||||
Objective | Introduction to modern biology and to principal biological concepts. | ||||
Content | The course is divided into several chapters: 1. Basic principles of Evolution. 2. Chemistry of Life: Water; Carbon and molecular diversity; biomolecules 3. The cell: structure; membrane structure and function, cell cycle 4. Metabolism: Respiration; Photosynthesis; Fermentation 5. Inheritance: meiosis and sexual reproduction; Mendelian genetics, chromosomal basis of inheritance, molecular basis of inheritance, from gene to protein, regulation of gene expression; genomes and their evolution | ||||
Lecture notes | None. | ||||
Literature | The text-book "Biology" (Campbell, Reece) (10th edition) is the basis of the course. The structure of the course is largely identical with that of the text-book. | ||||
Prerequisites / Notice | Certain sections of the text-book must be studied by self-instruction. | ||||
551-0371-00L | Growth Control: Insights from Yeast and Flies Number of participants limited to 8. | 6 credits | 7G | H. Stocker, R. C. Dechant, E. Hafen, M. Peter | |
Abstract | All organisms have to control their growth in accordance with environmental conditions. This course focuses on the analysis of growth regulation in the model organisms yeast and Drosophila. The participants will perform experiments in small teams to study insulin/TOR signaling as a key regulator of cellular growth. A particular focus will be the discussion of current research. | ||||
Objective | The aims of the block course are that participants (I) understand the function and evolution of insulin/TOR signaling (II) learn how genetic approaches in different organisms contribute to the understanding of human diseases such as cancer (III) will get familiarized with reading and discussing research articles (IV) get a first exposure to current research. | ||||
Content | The block course consists of (I) experiments: Teams of two students each will join research labs to work on current projects focusing on growth regulation in both single-cell eukaryotes (yeast) and multicellular animals (Drosophila). The students will present their projects and results to their colleagues. (II) lectures on growth regulation in yeast and Drosophila. (III) journal clubs to discuss recent literature. | ||||
Lecture notes | Lecture handouts | ||||
Literature | Original research articles will be discussed during the course. | ||||
551-0571-00L | From DNA to Diversity (University of Zurich) No enrolment to this course at ETH Zurich. Book the corresponding module directly at UZH. UZH Module Code: BIO336 Mind the enrolment deadlines at UZH: Link | 2 credits | 2V | A. Hajnal, D. Bopp, E. Hafen | |
Abstract | The evolution of the various body-plans is investigated by means of comparison of developmentally essential control genes of molecularly analysed model organisms. | ||||
Objective | By the end of this module, each student should be able to - recognize the universal principles underlying the development of different animal body plans. - explain how the genes encoding the molecular toolkit have evolved to create animal diversity. - relate changes in gene structure or function to evolutionary changes in animal development. Key skills: By the end of this module, each student should be able to - present and discuss a relevant evolutionary topic in an oral presentation - select and integrate key concepts in animal evolution from primary literature - participate in discussions on topics presented by others | ||||
551-0916-00L | Learning and Teaching Biology Does not take place this semester. Number of participants limited to 20 The block course will only take place with a minimum of 10 participants. | 6 credits | 7G | E. Hafen | |
Abstract | This course represents an introduction to recent research into student learning on the conceptual foundations of modern biology, together with pedagogical methods associated with effective instruction and its valuation. Students will be involved in active research into conceptual and practical issues involved in biology education and methods to discover student preconceptions. | ||||
Objective | Provides an overview on student's learning and shows ways to make the classroom experience more engaging and effective for students. Students will learn to produce a research-based paper on a project they work on during the course. | ||||
Literature | The course is not taught by a particular book, but recommended literature (review articles and selected primary literature) will be provided during the course. See the introductory video to the course here: http://youtu.be/GFJuNncSsdE | ||||
551-0963-00L | Specialized Biology Course with an Educational Focus: Teaching Diploma Specialised Courses in the Respective Subject with an Educational Focus in Biology for Teaching Diploma. | 12 credits | 26A | E. Hafen, J. Egli, W.‑D. Hardt, M. Zwicky | |
Abstract | Specialist aspects of biology are covered from the angle of imparting these to pupils, their historical development, and their significance for the subject, the individual and society. | ||||
Objective | After successfully completing the module, students should be in a position: - to call up more in-depth specialist knowledge of biology, covering a wide range of topics, and to impart this to others. - to explain biological concepts and principles, as well as the way they fit together. - to analyse controversial topics and to give factual explanations for these. - to conduct more in-depth work on a research topic and to compile a tuition unit based on this topic - to prepare tuition units involving complex learning matter at a high specialist level which are suitably tailored to the recipients, and to teach these in a manner conducive to learning. | ||||
Content | Demanding biological topics are dealt with under consideration of the special needs of persons involved in teaching. The module comprises the parts: 1) Lecture (Tues. 08.00-09.45 hrs) 2) Colloquium (every second Tues. 10.15-12.00 hrs., begins on first lecture day) 3) Seminar with presentation (every second Tues. 10.15-12.00 hrs., begins in second lecture week) 4) Semester thesis in a research group (7 weeks) | ||||
Lecture notes | Unterlagen für den Unterricht werden online mit Hilfe der e-learning Platform OLAT abgegeben. | ||||
Literature | Literatur und Literaturhinweise werden mit der e-learning Platform OLAT abgegeben. | ||||
Prerequisites / Notice | This Course lasts for two semesters. It can be started in autumn or in spring. Booking is only required once. Performance Assessment: Performance is assessed during the course of the entire modul, with a final test. Active participation in the colloquia and group seminars is required. The thesis report and an oral presentation have to be completed. The Specialized Biology Course with an Educational Focus (12 CP) can be acknowledged, in agreement with the advisor of the respective elective major, as one of the two obligatory research projects (each 15 CP). In such a case, additional 3 CP must be obtained in another course. In case of overbooking of the course, students enrolled in the Teaching Diploma in Biology will have priority for registration. The course is organized jointly with the University of Zurich (Fachbereich Biologie) and is held at the Life Science Zurich Learning Center of the ETH Zurich and the University of Zurich. | ||||
551-0963-02L | Specialized Biology Course with an Educational Focus II: Teaching Diploma Specialised Courses in the Respective Subject with an Educational Focus in Biology ONLY for students upgrading TC to Teaching Diploma. | 6 credits | 13A | E. Hafen, J. Egli, M. Zwicky | |
Abstract | Specialized aspects of biology are dealt with under the viewpoint of their presentation, their historical development, their significance for the field, the individual and society. | ||||
Objective | The goal is to promote the ability to understand biological concepts, principles and their interrelationships and to communicate specialist knoweldge to various groups of recipients in an understandable manner. | ||||
Content | Demanding biological topics are dealt with under consideration of the special needs of persons involved in teaching. The module: 1) Lecture (Tues. 08.00-09.45 hrs) 2) Colloquium (every second Tues. 10.15-12.00 hrs., begins on first lecture day) 3) Seminar with presentation (every second Tues. 10.15-12.00 hrs., begins in second lecture week) 4) Semester thesis in a research group (3.5 weeks) | ||||
Lecture notes | None. | ||||
Literature | Specific references will be made available for the individual projects. | ||||
Prerequisites / Notice | The program of this course represents one half (6 CP) of that of the Specialized Biology Course with an Educational Focus (551-0963-00, 12 CP). |