Christian Frei: Katalogdaten im Frühjahrssemester 2019
| Name | Herr Dr. Christian Frei |
| Adresse | Inst. f. Biomedizinische Technik ETH Zürich, ETZ F 83 Gloriastrasse 35 8092 Zürich SWITZERLAND |
| Telefon | +41 44 632 45 85 |
| frei@biomed.ee.ethz.ch | |
| Departement | Informationstechnologie und Elektrotechnik |
| Beziehung | Dozent |
| Nummer | Titel | ECTS | Umfang | Dozierende | |
|---|---|---|---|---|---|
| 227-0945-10L | Cell and Molecular Biology for Engineers II This course is part II of a two-semester course. Knowledge of part I is required. | 3 KP | 2G | C. Frei | |
| Kurzbeschreibung | The course gives an introduction into cellular and molecular biology, specifically for students with a background in engineering. The focus will be on the basic organization of eukaryotic cells, molecular mechanisms and cellular functions. Textbook knowledge will be combined with results from recent research and technological innovations in biology. | ||||
| Lernziel | After completing this course, engineering students will be able to apply their previous training in the quantitative and physical sciences to modern biology. Students will also learn the principles how biological models are established, and how these models can be tested. | ||||
| Inhalt | Lectures will include the following topics: DNA, chromosomes, RNA, protein, genetics, gene expression, membrane structure and function, vesicular traffic, cellular communication, energy conversion, cytoskeleton, cell cycle, cellular growth, apoptosis, autophagy, cancer, development and stem cells. In addition, 4 journal clubs will be held, where recent publications will be discussed (2 journal clubs in part I and 2 journal clubs in part II). For each journal club, students (alone or in groups of up to three students) have to write a summary and discussion of the publication. These written documents will be graded and count as 40% for the final grade. | ||||
| Skript | Scripts of all lectures will be available. | ||||
| Literatur | "Molecular Biology of the Cell" (6th edition) by Alberts, Johnson, Lewis, Morgan, Raff, Roberts, and Walter. | ||||
| 227-0949-10L | Biological Methods for Engineers (Advanced Lab)  Limited number of participants. Students of the MSc in Biomedical Engineering have priority. | 4 KP | 9P | C. Frei | |
| Kurzbeschreibung | The 2 week-long, full-time block course covers basic laboratory skills and safety, cell culture, protein analysis, RNA/DNA Isolation and RT-PCR. Each topic will be introduced, followed by practical work at the bench. | ||||
| Lernziel | The goal of this laboratory course is to give students practical exposure to basic techniques of cell and molecular biology. | ||||
| Inhalt | The goal of this laboratory course is to give students practical exposure to basic techniques of cell and molecular biology. | ||||
| Voraussetzungen / Besonderes | Enrollment is limited and preference given to students in the Masters of Biomedical Engineering program. | ||||
| 752-0100-AAL | Biochemistry Belegung ist NUR erlaubt für MSc Studierende, die diese Lerneinheit als Auflagenfach verfügt haben. Alle anderen Studierenden (u.a. auch Mobilitätsstudierende, Doktorierende) können diese Lerneinheit NICHT belegen. | 2 KP | 4R | C. Frei | |
| Kurzbeschreibung | Grundlegende Kenntnisse der Enzymologie, insbesondere die Struktur, Kinetik und Chemie von enzymkatalysierten Reaktionen in vitro und in vivo. Stoffwechselbiochemie: Absolvierende sind in der Lage, wesentliche zelluläre Stoffwechselvorgänge zu beschreiben und zu verstehen. | ||||
| Lernziel | In this self-study course, the students will gain solid biochemical knowledge about enzymology, membrane biochemistry, and central metabolism. | ||||
| Inhalt | Program Introduction, basics, composition of cells, biochemical units, repetition of relevant organic chemistry Structure and function of proteins Carbohydrates, structure of DNA Lipids an biological membranes Enzymes and enzyme kinetics Catalytic strategies Metabolism: Basic concepts and design. Repetition of basic thermodynamics Glycolysis The citric acid cycle Oxidative phosphorylation Fatty acid metabolism | ||||
| Skript | Horton et al. (Pearson) serves as lecture notes. | ||||
| Literatur | Horton, Moran, Scrimgeour, Perry, Rawn: Principles of Biochemistry, 4th ed. or Moran, Horton, Scrimgeour, Perry: Principles of Biochemistry, 5th ed. Pearson Education Limited, Essex | ||||
| Voraussetzungen / Besonderes | Basic knowledge in biology and chemistry is a precondition. | ||||