Christian Frei: Catalogue data in Autumn Semester 2017 |
Name | Dr. Christian Frei |
Address | Inst. f. Biomedizinische Technik ETH Zürich, GLC F 12.2 Gloriastrasse 37/ 39 8092 Zürich SWITZERLAND |
Telephone | +41 44 632 45 85 |
frei@biomed.ee.ethz.ch | |
Department | Information Technology and Electrical Engineering |
Relationship | Lecturer |
Number | Title | ECTS | Hours | Lecturers | |
---|---|---|---|---|---|
227-0945-00L | Cell and Molecular Biology for Engineers I This course is part I of a two-semester course. | 3 credits | 3G | C. Frei | |
Abstract | The course gives an introduction into cellular and molecular biology, specifically for students with a background in engineering. The focus will be on the basic organization of eukaryotic cells, molecular mechanisms and cellular functions. Textbook knowledge will be combined with results from recent research and technological innovations in biology. | ||||
Objective | After completing this course, engineering students will be able to apply their previous training in the quantitative and physical sciences to modern biology. Students will also learn the principles how biological models are established, and how these models can be tested. | ||||
Content | Lectures will include the following topics: DNA, chromosomes, RNA, protein, genetics, gene expression, membrane structure and function, vesicular traffic, cellular communication, energy conversion, cytoskeleton, cell cycle, cellular growth, apoptosis, autophagy, cancer, development and stem cells. In addition, three journal clubs will be held, where one/two publictions will be discussed (part I: 1 Journal club, part II: 2 Journal Clubs). For each journal club, students (alone or in groups of up to three students) have to write a summary and discussion of the publication. These written documents will be graded and count as 25% for the final grade. | ||||
Lecture notes | Scripts of all lectures will be available. | ||||
Literature | "Molecular Biology of the Cell" (6th edition) by Alberts, Johnson, Lewis, Raff, Roberts, and Walter. | ||||
227-0949-00L | Biological Methods for Engineers (Basic Lab) Number of participants limited to 10. | 2 credits | 4P | C. Frei | |
Abstract | The course during 4 afternoons (13h to 18h) covers basic laboratory skills and safety, cell culture, protein analysis, RNA/DNA Isolation and RT-PCR. Each topic will be introduced, followed by practical work at the bench. Presence during the course is mandatory. | ||||
Objective | The goal of this laboratory course is to give students practical exposure to basic techniques of cell and molecular biology. | ||||
Content | The goal of this laboratory course is to give students practical exposure to basic techniques of cell and molecular biology. | ||||
Prerequisites / Notice | Enrollment is limited and students from the Master's programme in Biomedical Engineering (BME) have priority. | ||||
752-0100-AAL | Biochemistry Enrolment ONLY for MSc students with a decree declaring this course unit as an additional admission requirement. Any other students (e.g. incoming exchange students, doctoral students) CANNOT enrol for this course unit. | 2 credits | 4R | C. Frei | |
Abstract | Basic knowledge of enzymology, in particular the structure, kinetics and chemistry of enzyme-catalysed reaction in vitro and in vivo. Biochemistry of metabolism: Those completing the course are able to describe and understand fundamental cellular metabolic processes. | ||||
Objective | Based on the biology and chemistry courses in the 1. and 2. semester more detailed biochemical knowledge about enzymology, membrane biochemistry, and central metabolism will be presented | ||||
Content | Program Introduction, basics, composition of cells, biochemical units, repetition of relevant organic chemistry Structure and function of proteins Carbohydrates, structure of DNA Lipids an biological membranes Enzymes and enzyme kinetics Catalytic strategies Metabolism: Basic concepts and design. Repetition of basic thermodynamics Glycolysis The citric acid cycle Oxidative phosphorylation Fatty acid metabolism | ||||
Lecture notes | Principles of Biochemistry (5th Edition) 5th Edition by Laurence A. Moran (Author), Robert A Horton (Author), Gray Scrimgeour (Author), Marc Perry (Author) | ||||
Literature | Principles of Biochemistry (5th Edition) 5th Edition by Laurence A. Moran (Author), Robert A Horton (Author), Gray Scrimgeour (Author), Marc Perry (Author) | ||||
Prerequisites / Notice | Basic knowledge in biology and chemistry is a precondition. | ||||
752-0100-00L | Biochemistry | 2 credits | 2V | C. Frei | |
Abstract | Basic knowledge of enzymology, in particular the structure, kinetics and chemistry of enzyme-catalysed reaction in vitro and in vivo. Biochemistry of metabolism: Those completing the course are able to describe and understand fundamental cellular metabolic processes. | ||||
Objective | Students are able to understand - the structure and function of biological macromolecules - the kinetic bases of enzyme reactions - thermodynamic and mechanistic basics of relevant metabolic processes Students are able to describe the relevant metabolic reactions in detail | ||||
Content | Program Introduction, basics, composition of cells, biochemical units, repetition of relevant organic chemistry Structure and function of proteins Carbohydrates Lipids an biological membranes Enzymes and enzyme kinetics Catalytic strategies Metabolism: Basic concepts and design. Repetition of basic thermodynamics Glycolysis, fermentation The citric acid cycle Oxidative phosphorylation Fatty acid metabolism | ||||
Lecture notes | Horton et al. (Pearson) serves as lecture notes. | ||||
Prerequisites / Notice | Basic knowledge in biology and chemistry is a precondition. |