Antonio Lanzavecchia: Catalogue data in Autumn Semester 2016 |
Name | Prof. em. Dr. Antonio Lanzavecchia |
Address | Institut für Mikrobiologie ETH Zürich, HCI F 417 Vladimir-Prelog-Weg 1-5/10 8093 Zürich SWITZERLAND |
lanzavecchia@micro.biol.ethz.ch | |
Department | Biology |
Relationship | Professor emeritus |
Number | Title | ECTS | Hours | Lecturers | |
---|---|---|---|---|---|
551-0223-00L | Immunology III | 4 credits | 2V | M. Kopf, M. Bachmann, J. Kisielow, A. Lanzavecchia, S. R. Leibundgut, A. Oxenius, R. Spörri | |
Abstract | This course provides a detailed understanding of - development of T and B cells - the dynamics of a immune response during acute and chronic infection - mechanisms of immunopathology - modern vaccination strategies Key experimental results will be shown to help understanding how immunological text book knowledge has evolved. | ||||
Objective | Obtain a detailed understanding of - the development, activation, and differentiation of different types of T cells and their effectormechanisms during immune responses, - Recognition of pathogenic microorganisms by the host cells and molecular events thereafter, - events and signals for maturation of naive B cells to antibody producing plasma cells and memory B cells. - Optimization of B cell responses by intelligent design of new vaccines | ||||
Content | o Development and selection of CD4 and CD8 T cells, natural killer T cells (NKT), and regulatory T cells (Treg) o NK T cells and responses to lipid antigens o Differentiation, characterization, and function of CD4 T cell subsets such as Th1, Th2, and Th17 o Overview of cytokines and their effector function o Co-stimulation (signals 1-3) o Dendritic cells o Evolution of the "Danger" concept o Cells expressing Pattern Recognition Receptors and their downstream signals o T cell function and dysfunction in acute and chronic viral infections | ||||
Literature | Documents of the lectures are available for download at: https://moodle-app2.let.ethz.ch/course/view.php?id=2581¬ifyeditingon=1 | ||||
Prerequisites / Notice | Immunology I and II recommended but not compulsory | ||||
551-0509-00L | Current Immunological Research in Zürich | 0 credits | 1K | R. Spörri, M. Detmar, C. Halin Winter, W.‑D. Hardt, M. Kopf, A. Lanzavecchia, S. R. Leibundgut, A. Oxenius, University lecturers | |
Abstract | This monthly meeting is a platform for Zurich-based immunology research groups to present and discuss their ongoing research projects. At each meeting three PhD students or Postdocs from the participating research groups present an ongoing research project in a 30 min seminar followed by a plenary discussion. | ||||
Objective | The aim of this monthly meeting is to provide further education for master and doctoral students as well as Postdocs in diverse topics of immunology and to give an insight in the related research. Furthermore, this platform fosters the establishment of science- and technology-based interactions between the participating research groups. | ||||
Content | Presentation and discussion of current research projects carried out by various immunology-oriented research groups in Zurich. | ||||
Lecture notes | none | ||||
551-1143-00L | Analysis of Human T and B Cell Responses to Infectious Agents Number of participants limited to 8. | 6 credits | 7G | A. Lanzavecchia | |
Abstract | Students actively participate in ongoing research projects on the analysis of human T and B cell response to pathogens and vaccines. They will be tutored in small groups by doctoral students and postdocs. In a lecture series, the theoretical background for the projects will be provided and the students will have the opportunity to present their projects and discuss recent publications. | ||||
Objective | To learn current methodologies in human immunology through experimental work in the lab. To learn current concepts through lectures and discussion of original papers. Requirement for obtaining the credit points: oral presentation of the research project in a ppt format. |