Jeffrey W. Bode: Catalogue data in Autumn Semester 2021 |
Name | Prof. Dr. Jeffrey W. Bode |
Field | Synthetic Organic Chemistry |
Address | Lab. für Organische Chemie ETH Zürich, HCI F 315 Vladimir-Prelog-Weg 1-5/10 8093 Zürich SWITZERLAND |
Telephone | +41 44 633 21 03 |
bode@org.chem.ethz.ch | |
Department | Chemistry and Applied Biosciences |
Relationship | Full Professor |
Number | Title | ECTS | Hours | Lecturers | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
529-0016-00L | BCB III: Organic Chemistry | 8 credits | 12P | J. W. Bode | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Abstract | Laboratory course in Organic Chemistry for students of "Biochemisty - Chemical Biology" | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Objective | Introduction into basic techniques used in the organic laboratory. Understanding organic reactions through experiments. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Content | Part I: Basic operations such as the isolation, purification, and characterization of organic compounds: distillation, extraction, chromatography, crystallization, IR (UV/1H-NMR)-spectroscopy for the identification of the constitution of organic compounds. Part II: Organic reactions: preparative chemistry. From simple, one-step to multi-step syntheses. The syntheses include classic Organic Chemistry as well as methods widely used in a Chemical Biology context. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Lecture notes | see https://bode.ethz.ch/education/bcb-iii/bcb-iii-lab-course.html | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Literature | R. K. Müller, R. Keese: "Grundoperationen der präparativen organischen Chemie"; J. Leonard, B. Lygo, G. Procter: "Praxis der Organischen Chemie" (Übersetzung herausgegeben von G. Dyker), VCH, Weinheim, 1996, ISBN 3-527-29411-2 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Prerequisites / Notice | Basisprüfung + BCB I: General Chemistry | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Competencies |
| |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
529-0241-10L | Advanced Methods and Strategies in Synthesis | 6 credits | 3G | J. W. Bode | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Abstract | Advanced Modern Methods and Strategies in Synthesis | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Objective | Knowledge of modern methods in asymmetric stereocontrol, enantioselective catalysis, and organic reaction mechanisms. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Content | Current trends in methods for and approaches to synthesis of complex natural products, pharmaceuticals, and biological molecules; fragment coupling and protecting group strategies; chemical ligation and biomolecules synthesis; enantioselective catalysis including ligand design and optimization; cross coupling reactions from preactivated precursors; C-H activation and oxidation chemistry; building block synthesis with chiral auxiliaries and reagents; new concepts in asymmetric catalysis. Analysis of key primarily literature including identification of trends, key precendents, and emerging topics will be emphasized. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Lecture notes | will be provided in class and online | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Literature | Suggesting Textbooks 1. Walsh and Kozlowski, Fundamentals of Asymmetric Catalysis, 1st Ed., University Science Books, 2009. 2. Anslyn and Dougherty, Modern Physical Organic Chemistry, 1st Ed., University Science Books, 2006. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
529-0290-00L | Organic Chemistry (Seminar) | 0 credits | 2S | E. M. Carreira, J. W. Bode, H. Wennemers, R. Zenobi | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Abstract | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Objective | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
529-0299-00L | Organic Chemistry | 0 credits | 1.5K | J. W. Bode, E. M. Carreira, P. Chen, H. Wennemers, R. Zenobi | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Abstract | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Objective |