Andrew de Mello: Catalogue data in Autumn Semester 2014 |
Name | Prof. Dr. Andrew de Mello |
Field | Biochemical Engineering |
Address | Inst. f. Chemie- u. Bioing.wiss. ETH Zürich, HCI F 115 Vladimir-Prelog-Weg 1-5/10 8093 Zürich SWITZERLAND |
Telephone | +41 44 633 66 10 |
andrew.demello@chem.ethz.ch | |
URL | https://www.demellogroup.ethz.ch |
Department | Chemistry and Applied Biosciences |
Relationship | Full Professor |
Number | Title | ECTS | Hours | Lecturers | |
---|---|---|---|---|---|
529-0010-00L | Chemistry | 3 credits | 2V + 1U | A. de Mello, C. S. Elvira Bermejo | |
Abstract | This is a general chemistry course aimed at first year undergraduate students in the Department of Mechanical and Process Engineering (D-MAVT). | ||||
Objective | The aims of the course are as follows: 1) To provide a thorough understanding of the basic principles of chemistry and its application. 2) To develop an understanding of the atomic and molecular nature of matter and of the chemical reactions that describe their transformations. 3) To emphasize areas considered most relevant in an engineering context. | ||||
Content | Electronic structure of atoms, chemical bonding, molecular shape and bonding theory, gases, thermodynamics, chemical thermodynamics, chemical kinetics, equilibria, solutions and intermolecular forces, redox and electrochemistry. | ||||
Literature | The course is based on "Chemistry the Central Science" by Brown, LeMay, Bursten, Murphy and Woodward. Pearson, 12th Edition (international edition). | ||||
529-0837-00L | Biomicrofluidic Engineering | 7 credits | 3G | A. de Mello | |
Abstract | Microfluidics describes the behaviour, control and manipulation of fluids that are geometrically constrained within sub-microliter environments. The use of microfluidic devices offers an opportunity to control physical and chemical processes with unrivalled precision, and in turn provides a route to performing chemistry and biology in an ultra-fast and high-efficiency manner. | ||||
Objective | In the course students will investigate the theoretical concepts behind microfluidic device operation, the methods of microfluidic device manufacture and the application of microfluidic architectures to important problems faced in modern day chemical and biological analysis. A design workshop will allow students to develop new microscale flow processes by appreciating the dominant physics at the microscale. The application of these basic ideas will primarily focus on biological problems and will include a treatment of diagnostic devices for use at the point-of-care, advanced functional material synthesis, DNA analysis, proteomics and cell-based assays. Lectures, assignments and the design workshop will acquaint students with the state-of-the-art in applied microfluidics. | ||||
Content | Specific topics in the course include, but not limited to: 1. Theoretical Concepts Features of mass and thermal transport on the microscale Key scaling laws 2. Microfluidic Device Manufacture Conventional lithographic processing of rigid materials Soft lithographic processing of plastics and polymers Mass fabrication of polymeric devices 3. Unit operations and functional components Analytical separations (electrophoresis and chromatography) Chemical and biological synthesis Sample pre-treatment (filtration, SPE, pre-concentration) Molecular detection 4. Design Workshop Design of microfluidic architectures for PCR, distillation & mixing 5. Contemporary Applications in Biological Analysis Microarrays Cellular analyses (single cells, enzymatic assays, cell sorting) Proteomics 6. System integration Applications in radiochemistry, diagnostics and high-throughput experimentation | ||||
Lecture notes | Lecture handouts will be provided | ||||
Prerequisites / Notice | This lecture will be recorded for Students of Basel (BSSE), details will be announced later. |