From 2 November 2020, the autumn semester 2020 will take place online. Exceptions: Courses that can only be carried out with on-site presence.
Please note the information provided by the lecturers via e-mail.

Martin Pilhofer: Catalogue data in Autumn Semester 2016

Name Prof. Dr. Martin Pilhofer
FieldCryo-Electron Microscopy
Inst. f. Molekularbiol.u.Biophysik
ETH Zürich, HPK F 13
Otto-Stern-Weg 5
8093 Zürich
Telephone+41 44 633 39 63
RelationshipAssociate Professor

551-0313-00LMicrobiology (Part I) Information 3 credits2VW.‑D. Hardt, L. Eberl, H.‑M. Fischer, J. Piel, M. Pilhofer
AbstractAdvanced lecture class providing a broad overview on bacterial cell structure, genetics, metabolism, symbiosis and pathogenesis.
ObjectiveThis concept class will be based on common concepts and introduce to the enormous diversity among bacteria and archaea. It will cover the current research on bacterial cell structure, genetics, metabolism, symbiosis and pathogenesis.
ContentAdvanced class covering the state of the research in bacterial cell structure, genetics, metabolism, symbiosis and pathogenesis.
Lecture notesUpdated handouts will be provided during the class.
LiteratureCurrent literature references will be provided during the lectures.
Prerequisites / NoticeEnglish
The lecture "Grundlagen der Biologie II: Mikrobiologie" is the basis for this advanced lecture.
551-1403-00LImaging Bacterial Cells in a Native State by Electron Cryotomography Restricted registration - show details
Number of participants limited to 3.
6 credits7GM. Pilhofer
AbstractThe goal is to acquire the techniques to image bacteria by electron cryotomography, resolving their structure in a native state, in 3D, and to macromolecular resolution. In a small group, students will perform wet lab experiments, data collection with stat-of-the-art equipment, data processing and analyses. The key method and its application in bacterial cell biology will be introduced by lectures
ObjectiveStudents will acquire the skills to cultivate bacteria, plunge-freeze samples for cryotomography, collect data using an electron cryomicroscope, process raw data, analyze tomograms, perform subtomogram averaging, model structures of interest, and generate movies for visualization.
551-1405-00LElectron Cryomicroscopy Seminar Information 0 credits0.5SM. Pilhofer, further lecturers
AbstractIntergroup seminar for scientists and students interested in electron cryomicroscopy
ObjectiveThe goal of the seminar is to provide an exchange forum for anyone interested in electron cryomicroscopy (tomography and single particle).
The first ~10 minutes are used for exchange on instrument status and technical issues, followed by a ~30 min presentation and discussion of a specific project.
The seminar can also be used to discuss current literature and report from conferences.
Prerequisites / NoticePresented project data are confidential. Sign-up for seminar announcements by emailing
551-1411-00LMolecular and Structural Biology III: Current Topics Restricted registration - show details
The course will only take place with a minimum of 6 participants.
2 credits1VK. Locher, F. Allain, N. Ban, R. Glockshuber, M. Pilhofer, E. Weber-Ban
AbstractThe course discusses current topics and cutting edge research in the structural, molecular, and biochemical study of cellular macromolecules. Student participation is an essential component of the course and will contribute to the exam grade
ObjectiveThe goal is to discuss cutting edge research in the structural, molecular, and biochemical study of cellular macromolecules. Students will also have an opportunity to present and discuss recent breakthroughs relevant to the research fields presented by the faculty teaching the course (see for details on the topics).
LiteratureWill be distributed by the instructors