Autumn Semester 2020 takes place in a mixed form of online and classroom teaching.
Please read the published information on the individual courses carefully.

Jacob Corn: Catalogue data in Autumn Semester 2019

Name Prof. Dr. Jacob Corn
FieldGenome Biology
Inst. f. Molecular Health Sciences
ETH Zürich, HPL J 36
Otto-Stern-Weg 7
8093 Zürich
Telephone+41 44 633 29 80
RelationshipFull Professor

551-0033-00LMolecular Genetics and Cell Biology Restricted registration - show details
Only for Health Sciences and Technology BSc and Human Medicine BSc.
5 credits5GJ. Corn, E. Hafen, K. Köhler
AbstractThis course teaches the basic principles of evolution, cell biology, molecular biology, genetics and developmental biology using the example of humans.
Objective1) Students can explain the importance of evolution for the development of humans and diseases.
2) The students know the cell as the smallest unit of the body. They can explain how the functions of the cell are disturbed in certain diseases and where therapies intervene. They can describe the multiplication of cells in the body and show how errors in this multiplication can lead to diseases.
3) The students know DNA as the basis of life. They can explain how the DNA information is stored and how this information can be reproduced and protected from damage. They can describe how the information is read and translated into proteins. They can explain which mechanisms at the level of DNA, RNA and proteins can cause diseases.
4) Students can explain which technologies can be used to diagnose and treat diseases.
5) Students can explain how people differ genetically and know the molecular basis of these differences. They can explain how these differences can lead to diseases and why some of these differences do not affect diseases.
6) The students know the molecular causes of the most common hereditary diseases and can determine the probability of occurrence and transmission to offspring.
7) Students can explain the biochemical and molecular basis of human reproduction and know the basic principles of human embryonic development. The students can explain which mechanisms can be disturbed by a faulty development.
8) Students know the historical development of biology and its effects on medicine and society.
551-1309-00LRNA-Biology Restricted registration - show details
Number of participants limited to 20.

The enrolment is done by the D-BIOL study administration.
6 credits7GF. Allain, C. Ciaudo, J. Corn, J. Hall, M. Jinek, S. Jonas, R. Santoro, O. Voinnet, K. Weis, A. Wutz
AbstractIntroduction to the diversity of current RNA-research at all levels from structural biology to systems biology using mainly model systems like S. cerevisiae (yeast), mammalian cells.
ObjectiveThe students will obtain an overview about the diversity of current RNA-research. They will learn to design experiments and use techniques necessary to analyze different aspects of RNA biology. Through lectures and literature seminars, they will learn about the burning questions of RNA research and discuss approaches to address these questions experimentally. In practical lab projects the students will work in one of the participating laboratories. Finally, they will learn how to present and discuss their data in an appropriate manner. Student assessment is a graded semester performance based on individual performance in the laboratory, the written exam and the poster presentation.
LiteratureDocumentation and recommended literature will be provided at the beginning and during the course.
Prerequisites / NoticeThe course will be taught in English.