From 2 November 2020, the autumn semester 2020 will take place online. Exceptions: Courses that can only be carried out with on-site presence.
Please note the information provided by the lecturers via e-mail.

Katharina Maniura: Catalogue data in Autumn Semester 2016

Name Prof. Dr. Katharina Maniura
EMPA St.Gallen
Lerchenfeldstrasse 5
9014 St. Gallen
Telephone071 274 7447
DepartmentHealth Sciences and Technology
RelationshipAdjunct Professor

376-1714-00LBiocompatible Materials4 credits3GK. Maniura, J. Möller, M. Zenobi-Wong
AbstractIntroduction to molecules used for biomaterials, molecular interactions between different materials and biological systems (molecules, cells, tissues). The concept of biocompatibility is discussed and important techniques from biomaterials research and development are introduced.
ObjectiveThe class consists of three parts:
1. Introdcution into molecular characteristics of molecules involved in the materials-to-biology interface. Molecular design of biomaterials.
2. The concept of biocompatibility.
3. Introduction into methodology used in biomaterials research and application.
ContentIntroduction into native and polymeric biomaterials used for medical applications. The concepts of biocompatibility, biodegradation and the consequences of degradation products are discussed on the molecular level. Different classes of materials with respect to potential applications in tissue engineering and drug delivery are introduced. Strong focus lies on the molecular interactions between materials having very different bulk and/or surface chemistry with living cells, tissues and organs. In particular the interface between the materials surfaces and the eukaryotic cell surface and possible reactions of the cells with an implant material are elucidated. Techniques to design, produce and characterize materials in vitro as well as in vivo analysis of implanted and explanted materials are discussed.
In addition, a link between academic research and industrial entrepreneurship is established by external guest speakers.
Lecture notesHandouts can be accessed online.
Biomaterials Science: An Introduction to Materials in Medicine, Ratner B.D. et al, 3rd Edition, 2013
Comprehensive Biomaterials, Ducheyne P. et al., 1st Edition, 2011

(available online via ETH library)

Handouts provided during the classes and references therin.