From 2 November 2020, the autumn semester 2020 will take place online. Exceptions: Courses that can only be carried out with on-site presence.
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535-0421-00L  Galenical Pharmacy I

SemesterAutumn Semester 2017
LecturersJ.‑C. Leroux, B. A. Gander
Periodicityyearly recurring course
Language of instructionEnglish


AbstractPrinciples and technologies for the manufacturing of dosage forms and drug delivery systems. Knowledge of pharm. excipients, materials, containers, liquid and semi-solid dosage forms, their production, function, quality and application. Comprehension of molecular interactions in solution and colloidal systems. Comprehension of interfacial phenomena and stabilization measures in dosage forms.
ObjectiveKnowledge of the most important pharmaceutical excipients, materials, containers, liquid and semi-solid dosage forms, of their production, function, quality, stability and application. Comprehension of the molecular interactions in solution and colloidal systems. Comprehension of interfacial phenomena and stabilization measures in disperse dosage forms.
ContentIntroduction and overview of important fundamentals, principles and technologies for the development and manufacturing of dosage forms and drug delivery systems. Overview of the most important pharmaceutical excipients and polymers, their structure, properties and processing; importance of materials properties for containers. Pharmaceutical solvents, fundamentals of solubility and solubilization of drugs. Water treatment processes, sterilization techniques and quality requirements of pharmaceutical water. Parenteral dosage forms and liquid ophthalmics. Surfactants, micelle formation and colloidal systems. Liquid suspensions and emulsions. Stabilization measures in dosage forms.
LiteratureL.V. Allen, N.G. Popovich, H.C. Ansel, Ansel's Pharmaceutical Dosage Forms and Drug Delivery Systems, 10th Ed, Lippincott Williams & Wilkins, Baltimore 2014.

M. E. Aulton and K. M. G. Taylor, Aulton's Pharmaceutics: The design and manufacture of medicines, 4th ed, Churchill Livingston, Philadelphia, 2013.

L. Felton, Remington - Essentials of Pharmaceutics, Pharmaceutical Press, London, 2013.

Sinko P.J., Martin's Physical Pharmacy and Pharmaceutical Sciences, 7th ed, Wolters Kluwer, Philadelphia, 2017.
Prerequisites / NoticeLanguage: German and English