529-0229-00L Practical Course Organic Chemistry (for Students of Biology and Pharmaceutical Sciences)
Semester | Autumn Semester 2016 |
Lecturers | C. Thilgen, F. Diederich, Y. Yamakoshi |
Periodicity | yearly recurring course |
Language of instruction | German |
Comment | Latest online enrolment is 10 days before the beginning of the semester. |
Abstract | Analytical part: basic operations for the separation of mixtures of organic compounds (recrystallization, distillation, extraction, chromatography) Synthetic part (main part): at least 8 synthetic steps (one- or two-step syntheses). |
Objective | Learn the basic techniques for the preparation and purification of organic compounds. Learn to take accurate notes of the experiments. Deepen the understanding of reaction mechanisms. |
Content | Analytical part: basic operations for the separation of mixtures of organic compounds (recrystallization, distillation, extraction, chromatography). Synthetic part (main part): at least 8 synthetic steps (one- or two-step syntheses). Introduction to database searches (Reaxys, SciFinder). |
Lecture notes | Documentation will be handed out at the beginning of the course. |
Literature | 1) P. Wörfel, M. Bitzer, U. Claus, H. Felber, M. Hübel, B. Vollenweider, Laborpraxis (Bd. 1: Einführung, allgemeine Methoden; Bd. 2: Messmethoden; Bd. 3: Trennungsmethoden; Bd. 4: Analytische Methoden), Birkhäuser Verlag. 2) J. Leonard, B. Lygo, G. Procter, Advanced Practical Organic Chemistry, Blackie Ltd., Glasgow, 1995. (Advanced level). 3) R. K. Müller, R. Keese: "Grundoperationen der präparativen organischen Chemie", 5. Aufl. 1994, ISBN 3 260 05364 6. |
Prerequisites / Notice | The basic reactions of Organic Chemistry and their mechanisms should be known (cf. course 529-1012-00L Organic Chemistry II for Students of Biology, Pharmaceutical Sciences, and Health Sci. and Tech.). As a prerequisite, all participants need to pass the "Safety Test HCI Chemie_V2 English" (see Link). A printout of the certificate generated by the system needs to be presented to the teaching assistants prior to starting lab work. |