529-0229-00L  Practical Course Organic Chemistry (for Students of Biology and Pharmaceutical Sciences)

SemesterAutumn Semester 2016
LecturersC. Thilgen, F. Diederich, Y. Yamakoshi
Periodicityyearly recurring course
Language of instructionGerman
CommentLatest online enrolment is 10 days before the beginning of the semester.


AbstractAnalytical part: basic operations for the separation of mixtures of organic compounds (recrystallization, distillation, extraction, chromatography)
Synthetic part (main part): at least 8 synthetic steps (one- or two-step syntheses).
ObjectiveLearn the basic techniques for the preparation and purification of organic compounds.
Learn to take accurate notes of the experiments.
Deepen the understanding of reaction mechanisms.
ContentAnalytical part: basic operations for the separation of mixtures of organic compounds (recrystallization, distillation, extraction, chromatography).
Synthetic part (main part): at least 8 synthetic steps (one- or two-step syntheses).
Introduction to database searches (Reaxys, SciFinder).
Lecture notesDocumentation will be handed out at the beginning of the course.
Literature1) P. Wörfel, M. Bitzer, U. Claus, H. Felber, M. Hübel, B. Vollenweider, Laborpraxis (Bd. 1: Einführung, allgemeine Methoden; Bd. 2: Messmethoden; Bd. 3: Trennungsmethoden; Bd. 4: Analytische Methoden), Birkhäuser Verlag.
2) J. Leonard, B. Lygo, G. Procter, Advanced Practical Organic Chemistry, Blackie Ltd., Glasgow, 1995. (Advanced level).
3) R. K. Müller, R. Keese: "Grundoperationen der präparativen organischen Chemie", 5. Aufl. 1994, ISBN 3 260 05364 6.
Prerequisites / NoticeThe basic reactions of Organic Chemistry and their mechanisms should be known (cf. course 529-1012-00L Organic Chemistry II for Students of Biology, Pharmaceutical Sciences, and Health Sci. and Tech.).

As a prerequisite, all participants need to pass the "Safety Test HCI Chemie_V2 English" (see Link). A printout of the certificate generated by the system needs to be presented to the teaching assistants prior to starting lab work.