551-0347-00L Molecular Mechanisms of Cell Growth and Polarity
|Semester||Autumn Semester 2016|
|Lecturers||R. Kroschewski, Y. Barral, S. Jessberger, M. Peter|
|Periodicity||yearly recurring course|
|Language of instruction||English|
|Comment||Number of participants limited to 12.|
|Abstract||Introduction to the principles and molecular mechanisms of cell polarity, using animal cells and fungi as model systems.|
|Objective||The students learn to describe the principles and molecular mechanisms of cell polarity, using different model systems as examples: |
- Animal cells during epithelial and neuronal differentiation
- Fungi during morphogenesis and aging.
Based on lectures, literature reading, discussions, presentations and practical lab work the students will be able to compare experimental strategies in different model systems, and to develop open questions in the field of cell polarity. Students will also know about the mechanisms and consequences of asymmetric cell division such as those performed by stem cells and asymmetric protein functions during morphogenesis and aging.
|Content||During this Block-Course, the students will learn to |
(1) describe and compare the principles and molecular mechanisms of cell polarity in fungi and animal cells,
(2) apply, evaluate and compare experimental strategies in the different model systems, and
(3) select the best model system to answer a particular question.
Students - in groups of 2 or max 3- will be integrated into a research project connected to the subject of the course, within one of the participating research groups.
Lectures and technical notes will be given and informal discussions held to provide you with the theoretical background.
|Lecture notes||There will be optional papers to be read before the course start. They serve as framework orientation for the practical parts of this block course and will be made accessible to you shortly before the course starts on the relevant Moodle site.|
|Literature||Documentation and recommended literature (review articles) will be provided during the course.|