529-0733-01L Enzymes
Semester | Autumn Semester 2018 |
Lecturers | D. Hilvert |
Periodicity | yearly recurring course |
Language of instruction | English |
Abstract | Principles of enzymatic catalysis, enzyme kinetics, mechanisms of enzyme-catalyzed reactions (group transfer reactions, carbon-carbon bond formation, eliminations, isomerisations and rearrangements), cofactor chemistry, enzymes in organic synthesis and the biosynthesis of natural products, catalytic antibodies. |
Objective | Overview of enzymes, enzyme-catalyzed reactions and metabolic processes. |
Content | Principles of enzymatic catalysis, enzyme kinetics, mechanisms of enzyme catalyzed reactions (group transfer reactions, carbon-carbon bond formation, eliminations, isomerisations and rearrangements), cofactor chemistry, enzymes in organic synthesis and the biosynthesis of natural products, catalytic antibodies. |
Lecture notes | A script will not be handed out. |
Literature | General: T. Bugg, An Introduction to Enzyme and Coenzyme Chemistry, Blackwell Science Ltd., Oxford, 1997. In addition, citations from the original literature relevant to the individual lectures will be assigned weekly. |