Fundamentals in functional genome analysis will be teached in this interactive lecture and the practical part. The topics will include the areas transcriptomics, proteomics, and epigenetics, and their impact on research in domestic animals.
The conveyed knowledge shall enable the students to recognize the potential impact of omics technologies on the research in the context of animal physiology and genetics as well as on future animal production. Recently published studies in the field of reproductive biology will be discussed with regard to agricultural sciences.
A main focus of this lecture and the corresponding practical course will be on next-generation sequencing technologies, e.g., RNA sequencing (RNA-Seq), small RNA-Seq, as well as methyl-Seq und ChIP-Seq. In proteomics, methodological basics will be given, such as 2D gel-based and mass spectrometry approaches. An important point of the lecture and the subsequent practical course will be the bioinformatics data analysis. Fundamental principles and strategies for the analysis of genomics data will be discussed and basic bioinformatics analyses will be performed.
A selection of review articles will be provided at the beginning oft he lecture series.