535-0250-00L  Biotransformation of Drugs and Xenobiotics

SemesterAutumn Semester 2016
LecturersS.‑D. Krämer
Periodicityyearly recurring course
Language of instructionEnglish



Courses

NumberTitleHoursLecturers
535-0250-00 VBiotransformation of Drugs and Xenobiotics1 hrs
Tue/107:45-09:30HCI H 2.1 »
01.11.07:45-08:30HCI G 3 »
S.‑D. Krämer

Catalogue data

AbstractKnowledge of the major reactions of biotransformation in drug therapy, prediction of possible metabolites of drugs and xenobiotics, recognition of structure elements and reactions which can lead to toxic metabolites. Knowledge of inter- and intraindividual factors influencing metabolism.
ObjectiveGoals: knowledge of the major reactions of biotransformation in drug therapy, prediction of possible metabolites of drugs and xenobiotics, recognition of structure elements and reactions which can lead to toxic metabolites. Knowledge of inter- and intraindividual factors influencing metabolism.
ContentMajor reactions of biotransformation. Major enzymes and reaction partners involved in the biotransformation of drugs and xenobiotics. Toxic reactions of metabolites. Factors which affect the biotransformation.
Lecture notesBiotransformation of drugs and xenobiotics
LiteratureB. Testa and S.D. Krämer. The Biochemistry of Drug Metabolism: Volumes 1 and 2, VHCA, Zürich, 2008 and 2010.

B. Testa and S.D. Krämer. The Biochemistry of Drug Metabolism: Parts 1 to 7. Published in Chemistry & Biodiversity, 2006-2009.

Performance assessment

Performance assessment information (valid until the course unit is held again)
Performance assessment as a semester course
ECTS credits1 credit
ExaminersS.-D. Krämer
Typegraded semester performance
Language of examinationEnglish
RepetitionRepetition possible without re-enrolling for the course unit.
Additional information on mode of examinationWritten exam towards the end of the cycle. Printouts and books but no electronic devices are allowed during the exam.

Learning materials

 
LiteratureB. Testa, S.D. Krämer. The Biochemistry of Drug Metabolism. Vol. 1 & 2. Wiley 2008, 2010
Only public learning materials are listed.

Groups

No information on groups available.

Restrictions

There are no additional restrictions for the registration.

Offered in

ProgrammeSectionType
DAS Preparation for the Swiss Federal Examination in PharmacyFirst Series of CoursesWInformation
Medicinal and Industrial Pharmaceutical Sciences MasterCompulsory CoursesOInformation
Pharmaceutical Sciences MasterElectivesW DrInformation