The spring semester 2021 will certainly take place online until Easter. Exceptions: Courses that can only be carried out with on-site presence. Please note the information provided by the lecturers.

227-0943-00L  Radiobiology

SemesterAutumn Semester 2016
LecturersM. Pruschy
Periodicityyearly recurring course
Language of instructionEnglish



Catalogue data

AbstractThe purpose of this course is to impart basic knowledge in radiobiology in order to handle ionizing radiation and to provide a basis for predicting the radiation risk.
ObjectiveBy the end of this course the participants will be able to:
a) interpret the 5 Rs of radiation oncology in the context of the hallmarks of cancer
b) understand factors which underpin the differing radiosensitivities of different tumors
c) follow rational strategies for combined treatment modalities of ionizing radiation with targeted agents
d) understand differences in the radiation response of normal tissue versus tumor tissue
e) understand different treatment responses of the tumor and the normal tissue to differential clinical-related parameters of radiotherapy (dose rate, LET etc.).
ContentEinführung in die Strahlenbiologie ionisierender Strahlen: Allgemeine Grundlagen und Begriffsbestimmungen; Mechanismen der biologischen Strahlenwirkung; Strahlenwirkung auf Zellen, Gewebe und Organe; Modifikation der biologischen Strahlenwirkung; Strahlenzytogenetik: Chromosomenveränderungen, DNA-Defekte, Reparaturprozesse; Molekulare Strahlenbiologie: Bedeutung inter- und intrazellulärer Signalübermittlungsprozesse, Apoptose, Zellzyklus-Checkpoints; Strahlenrisiko: Strahlensyndrome, Krebsinduktion, Mutationsauslösung, pränatale Strahlenwirkung; Strahlenbiologische Grundlagen des Strahlenschutzes; Nutzen-Risiko-Abwägungen bei der medizinischen Strahlenanwendung; Prädiktive strahlenbiologische Methoden zur Optimierung der therapeutischen Strahlenanwendung.
Lecture notesBeilagen mit zusammenfassenden Texten, Tabellen, Bild- und Grafikdarstellungen werden abgegeben
LiteratureLiteraturliste wird abgegeben.
Für NDS-Absolventen empfohlen: Hall EJ; Giacchia A: Radiobiology for the Radiologist, 7th Edition, 2011
Prerequisites / NoticeThe former number of this course unit is 465-0951-00L.

Performance assessment

Performance assessment information (valid until the course unit is held again)
Performance assessment as a semester course
ECTS credits2 credits
ExaminersM. Pruschy
Typesession examination
Language of examinationEnglish
RepetitionThe performance assessment is offered every session. Repetition possible without re-enrolling for the course unit.
Mode of examinationoral 30 minutes
This information can be updated until the beginning of the semester; information on the examination timetable is binding.

Learning materials

No public learning materials available.
Only public learning materials are listed.

Courses

NumberTitleHoursLecturers
227-0943-00 VRadiobiology
The lecture on October 20 will not take place.
2 hrs
Thu13-15HCI J 6 »
M. Pruschy

Groups

No information on groups available.

Restrictions

There are no additional restrictions for the registration.

Offered in

ProgrammeSectionType
Biomedical Engineering MasterTrack Core CoursesWInformation
MAS in Medical PhysicsCore CoursesWInformation
MAS in Medical PhysicsCore CoursesOInformation