From 2 November 2020, the autumn semester 2020 will take place online. Exceptions: Courses that can only be carried out with on-site presence.
Please note the information provided by the lecturers via e-mail.

535-0023-00L  Computer-Assisted Drug Design (Practical Course)

SemesterAutumn Semester 2017
LecturersG. Schneider, J. A. Hiss
Periodicityyearly recurring course
Language of instructionEnglish
CommentLimited number of participants.



Catalogue data

AbstractThe practical course is open for master and graduate students to get an introduction into hands-on computer-assisted drug design. The class includes an introduction to computer-based screening of a virtual compound library, subsequent synthesis of candidate ligands, and biochemically testing for activity on pharmacologically important drug targets.
ObjectiveParticipants become familiar with state-of-the-art methodologies in a real-life computer-aided medicinal chemistry project. Participants work as small teams, perform literature research and discuss recent research findings. A seminar talk is to be given presenting the molecular design strategy chosen and the results obtained during the course.
ContentThe course offers the possibility for people with and without computational and or laboratory background to get an introduction into computer-assisted drug design, as well as practical training in a modern chemical laboratory. Using various software suites, the participants will computationally create and screen a virtual compound library for potential active small molecules. The process will involve an introduction to screening a virtual compound library, synthesizing candidate inhibitors, and biophysical testing against a pharmacologically important drug target.
Lecture notesDetailed information will be handed out during the course.
LiteratureTextbook:
Schneider, G. and Baringhaus, K.-H. (2008) Molecular Design - Concepts and Applications. Wiley-VCH, Weinheim, New York.
Prerequisites / NoticeThe class is organized as a two-week block course.
The number of participants is limited.

Kick-off meeting and confirmation of registration (Vorbesprechung und Platzvergabe): During the last lecture of the class "Computer-Assisted Drug Design" (535-0022-00)

Ideally, students interested in the course participated and successfully passed the lecture "Computer-Assisted Drug Design" (535-0022-00).

Performance assessment

Performance assessment information (valid until the course unit is held again)
Performance assessment as a semester course
ECTS credits4 credits
ExaminersG. Schneider, J. A. Hiss
Typeungraded semester performance
Language of examinationEnglish
RepetitionRepetition possible without re-enrolling for the course unit.
Additional information on mode of examinationOral presentation with questions

Learning materials

No public learning materials available.
Only public learning materials are listed.

Courses

NumberTitleHoursLecturers
535-0023-00 PPraktikum Computer-Assisted Drug Design
Permission from lecturers required for all students.
Block lecture: 22 Jan 2018 - 2 Feb 2018
Room: HCI G496
Mandatory kick-off meeting: 12 Dec 2017, 17:00 s.t., HCI G496
80s hrsby appt.G. Schneider, J. A. Hiss

Groups

No information on groups available.

Restrictions

GeneralPermission from lecturers required for all students

Offered in

ProgrammeSectionType
Pharmaceutical Sciences MasterElectives IWInformation
Pharmacy MasterElectivesWInformation