Autumn Semester 2020 takes place in a mixed form of online and classroom teaching.
Please read the published information on the individual courses carefully.

511-0000-00L  Drug Discovery and Development

SemesterAutumn Semester 2017
LecturersU. Thibaut, J. Hall
Periodicityyearly recurring course
Language of instructionEnglish



Catalogue data

AbstractThis course provides an overview over the concepts and processes employed in today's drug discovery and development. It has an introductory character but will also provide more detailed insights employing real life examples. The course combines lectures and interactive elements with active participation of the students.
ObjectiveStudents
- Understand the drug discovery process and can explain major approaches and relevant technical terms (for details see lecture notes).
- Understand and appreciate the content and timing of drug development process steps, development phases and decision criteria.
- Understand the concepts underlying drug product development through all the phases from preclinical and clinical development to regulatory submission, approval and market launch.
- Can differentiate between small molecule drug development and biological drug development.
- Understand the most important differences between legal and regulatory requirements for drug development and approval for the major markets EU and USA.
ContentDrug Discovery (day 1):

Introduction to drug discovery: the concepts of drug target selection, ligands/leads, the developability of drug candidates;
Overview over the principal approaches to drug discovery: rational drug design, the natural product approach, serendipity, repurposing as well as chemical libraries and high-throughput screening.

Drug Development (days 2 and 3):

Introduction to the industrial drug product development processes covering the following phases: preclinical research and development, clinical development, regulatory processes and market launch.
R&D support processes such as project management, quality management, pharmacovigilance and pharmacoeconomics will be covered as well as organizational and governance aspects of the pharmaceutical industry.
Lecture notesWill be published on "mystudies"
LiteratureG. Nahler (Hrsg.) Dictionary of pharmaceutical medicine, Springer, Wien, 2013 (3rd edition)
Further readings will be listed in the lecture notes.
Prerequisites / NoticeThis course provides the essential basic knowledge required for the industry-specific modules of the spring semester.

Performance assessment

Performance assessment information (valid until the course unit is held again)
Performance assessment as a semester course
ECTS credits2 credits
ExaminersU. Thibaut, J. Hall
Typeungraded semester performance
Language of examinationEnglish
RepetitionRepetition possible without re-enrolling for the course unit.
Admission requirementStudents have fully attended days 1, 2 and 3.
Additional information on mode of examinationWritten examination (multiple choice test) and oral participation.

Learning materials

No public learning materials available.
Only public learning materials are listed.

Courses

NumberTitleHoursLecturers
511-0000-00 GDrug Discovery and Development Special students and auditors need a special permission from the lecturers.
Permission from lecturers required for all students.
24s hrs
28.09.08-17HIT K 52 »
18.10.08-17HIT K 52 »
19.10.08-17HIT K 52 »
U. Thibaut, J. Hall

Groups

No information on groups available.

Restrictions

General : Special students and auditors need a special permission from the lecturers
Permission from lecturers required for all students
PriorityRegistration for the course unit is only possible for the primary target group
Primary target groupPharmaceutical Sciences MSc (512000)

Offered in

ProgrammeSectionType
Pharmaceutical Sciences MasterCore Courses IOInformation