636-0109-00L  Stem Cells: Biology and Therapeutic Manipulation

SemesterSpring Semester 2018
LecturersT. Schroeder
Periodicityyearly recurring course
Language of instructionEnglish
CommentAttention: This course was offered in previous semesters with the number: 636-0013-00L "Stem Cells: Biology and Therapeutic Manipulation". Students that already passed course 636-0013-00L cannot receive credits for course 636-0109-00L.



Courses

NumberTitleHoursLecturers
636-0109-00 GStem Cells: Biology and Therapeutic Manipulation3 hrs
Wed14-17BSA E 46 »
T. Schroeder

Catalogue data

AbstractStem cells are central in tissue regeneration and repair, and hold great potential for therapy. We will discuss the role of stem cells in health and disease, and possibilities to manipulate their behavior for therapeutic application. Basic molecular and cell biology, engineering and novel technologies relevant for stem cell research and therapy will be discussed.
ObjectiveUnderstanding of current knowledge, and lack thereof, in stem cell biology, regenerative medicine and required technologies. Theoretical preparation for practical laboratory experimentation with stem cells.
ContentWe will use different diseases to discuss how to potentially model, diagnose or heal them by stem cell based therapies. This will be used as a guiding framework to discuss relevant concepts and technologies in cell and molecular biology, engineering, imaging, bioinformatics, tissue engineering, that are required to manipulate stem cells for therapeutic application.

Topics will include:
- Embryonic and adult stem cells and their niches
- Induced stem cells by directed reprogramming
- Relevant basic cell biology and developmental biology
- Relevant molecular biology
- Cell culture systems
- Cell fates and their molecular control by transcription factors and signalling pathways
- Cell reprogramming
- Disease modelling
- Tissue engineering
- Bioimaging, Bioinformatics
- Single cell technologies

Performance assessment

Performance assessment information (valid until the course unit is held again)
Performance assessment as a semester course
ECTS credits4 credits
ExaminersT. Schroeder
Typeend-of-semester examination
Language of examinationEnglish
RepetitionA repetition date will be offered in the first two weeks of the semester immediately consecutive.
Additional information on mode of examinationJournal club paper presentation (individually or in teams) is a central element of this course, will be graded as pass/fail, and is required to enroll for the examination and to pass this course.
Oral exam 20 Minutes

Learning materials

No public learning materials available.
Only public learning materials are listed.

Groups

No information on groups available.

Restrictions

There are no additional restrictions for the registration.

Offered in

ProgrammeSectionType
Biotechnology MasterBiomelecular-OrientatedWInformation
Biotechnology MasterSystem-OrientatedWInformation
Computational Biology and Bioinformatics MasterBiologyWInformation