The complex relation between structural analysis, methods leading to desired transformations, and insight into reaction mechanisms is exemplified. Relations between retrosynthetic analysis of target structures, synthetic methods and their combination in a synthetic strategy.
Objective
Extension and deepening of the knowledge in organic synthesis and the principles of structure and reactivity.
Content
Concepts of the planning of organic synthesis (strategy and tactics), retrosynthetic analysis. Structure-reactivity relation in the context of the synthesis of complex molecules.
Literature
K. C. Nicolaou, E. J. Sorensen, Classics in Total Synthesis, Wiley-VCH 1996. K. C. Nicolaou, S. A. Snyder, Classics in Total Synthesis II, Wiley-VCH 2003. K. C. Nicolaou, J. Chen, Classics in Total Synthesis III, Wiley-VCH 2011.
Prerequisites / Notice
OC I-IV
Taught competencies
Subject-specific Competencies
Concepts and Theories
assessed
Techniques and Technologies
not assessed
Method-specific Competencies
Analytical Competencies
assessed
Decision-making
assessed
Media and Digital Technologies
not assessed
Problem-solving
assessed
Project Management
not assessed
Social Competencies
Communication
assessed
Cooperation and Teamwork
not assessed
Customer Orientation
not assessed
Leadership and Responsibility
not assessed
Self-presentation and Social Influence
not assessed
Sensitivity to Diversity
not assessed
Negotiation
assessed
Personal Competencies
Adaptability and Flexibility
not assessed
Creative Thinking
assessed
Critical Thinking
assessed
Integrity and Work Ethics
not assessed
Self-awareness and Self-reflection
not assessed
Self-direction and Self-management
not assessed
Performance assessment
Performance assessment information (valid until the course unit is held again)
Performance assessment as a semester course