529-0233-01L  Organic Synthesis: Methods and Strategies

SemesterAutumn Semester 2021
LecturersE. M. Carreira
Periodicityyearly recurring course
Language of instructionEnglish


AbstractThe complex relation between structural analysis, methods leading to desired transformations, and insight into reaction mechanisms is exemplified. Relations between retrosynthetic analysis of target structures, synthetic methods and their combination in a synthetic strategy.
ObjectiveExtension and deepening of the knowledge in organic synthesis and the principles of structure and reactivity.
ContentConcepts of the planning of organic synthesis (strategy and tactics), retrosynthetic analysis. Structure-reactivity relation in the context of the synthesis of complex molecules.
LiteratureK. C. Nicolaou, E. J. Sorensen, Classics in Total Synthesis, Wiley-VCH 1996.
K. C. Nicolaou, S. A. Snyder, Classics in Total Synthesis II, Wiley-VCH 2003.
K. C. Nicolaou, J. Chen, Classics in Total Synthesis III, Wiley-VCH 2011.
Prerequisites / NoticeOC I-IV
Taught competenciesTaught competencies
Subject-specific CompetenciesConcepts and Theoriesassessed
Techniques and Technologiesnot assessed
Method-specific CompetenciesAnalytical Competenciesassessed
Decision-makingassessed
Media and Digital Technologiesnot assessed
Problem-solvingassessed
Project Managementnot assessed
Social CompetenciesCommunicationassessed
Cooperation and Teamworknot assessed
Customer Orientationnot assessed
Leadership and Responsibilitynot assessed
Self-presentation and Social Influence not assessed
Sensitivity to Diversitynot assessed
Negotiationassessed
Personal CompetenciesAdaptability and Flexibilitynot assessed
Creative Thinkingassessed
Critical Thinkingassessed
Integrity and Work Ethicsnot assessed
Self-awareness and Self-reflection not assessed
Self-direction and Self-management not assessed