# 401-4788-16L Mathematics of (Super-Resolution) Biomedical Imaging

Semester | Spring Semester 2017 |

Lecturers | H. Ammari |

Periodicity | yearly course |

Language of instruction | English |

Abstract | The aim of this course is to review different methods used to address challenging problems in biomedical imaging. The emphasis will be on scale separation techniques, hybrid imaging, spectroscopic techniques, and nanoparticle imaging. These approaches allow one to overcome the ill-posedness character of imaging reconstruction in biomedical applications and to achieve super-resolution imaging. |

Objective | Super-resolution imaging is a collective name for a number of emerging techniques that achieve resolution below the conventional resolution limit, defined as the minimum distance that two point-source objects have to be in order to distinguish the two sources from each other. In this course we describe recent advances in scale separation techniques, spectroscopic approaches, multi-wave imaging, and nanoparticle imaging. The objective is fivefold: (i) To provide asymptotic expansions for both internal and boundary perturbations that are due to the presence of small anomalies; (ii) To apply those asymptotic formulas for the purpose of identifying the material parameters and certain geometric features of the anomalies; (iii) To design efficient inversion algorithms in multi-wave modalities; (iv) to develop inversion techniques using multi-frequency measurements; (v) to develop a mathematical and numerical framework for nanoparticle imaging. In this course we shall consider both analytical and computational matters in biomedical imaging. The issues we consider lead to the investigation of fundamental problems in various branches of mathematics. These include asymptotic analysis, inverse problems, mathematical imaging, optimal control, stochastic modelling, and analysis of physical phenomena. On the other hand, deriving mathematical foundations, and new and efficient computational frameworks and tools in biomedical imaging, requires a deep understanding of the different scales in the physical models, an accurate mathematical modelling of the imaging techniques, and fine analysis of complex physical phenomena. An emphasis is put on mathematically analyzing acoustic-electric imaging, thermo-elastic imaging, Lorentz force based imaging, elastography, multifrequency electrical impedance tomography, and plasmonic resonant nanoparticles. |