Suchergebnis: Katalogdaten im Herbstsemester 2017

Biologie Bachelor Information
3. Studienjahr, 5. Semester
Blockkurse
Anmeldung zu Blockkursen muss zwingend über die website Link erfolgen. Anmeldung möglich von 24.7.2017 bis 6.8.2017.
Blockkurse im 3. Semesterviertel
Von 7.11.2017 13:00 Uhr bis 29.11.2017 17:00 Uhr
NummerTitelTypECTSUmfangDozierende
551-0355-00LPhytopathology Belegung eingeschränkt - Details anzeigen
Number of participants limited to 12.

The enrolment is done by the D-BIOL study administration.
W6 KP7GM. Maurhofer Bringolf, B. McDonald
KurzbeschreibungTheoretische und praktische Grundkenntnisse der Phytopathologie (Interaktion von Pflanzen und pathogenen Mikroorganismen, Morphologie und Lebensweise von pflanzenpathogenen Pilzen, Evolution von pflanzenpathogenen Pilzen, biologische Bekämpfung von Pflanzenkrankheiten)
LernzielGrundkenntnisse der Phytopathologie (Interaktionen zwischen Pflanzen und pflanzenpathogenen Mikroorganismen, Morphologie und Lebensweise von pflanzenpathogenen Pilzen, Evolution von pflanzenpathogenen Pilzenpflanzenpathogenen Pilzen, biologische Bekämpfung von Pflanzenkrankheiten)

Einblick in aktuelle Forschungsprojekte in Theorie und Praxis
InhaltPraktischer Unterricht:

Durchführung von Versuchen im Rahmen von aktuellen Forschungsprojekten in der Phytopathologie
Makro- und mikroskopische Diagnostik von Pflanzenkrankheiten

Theoretischer Unterricht:

Einführung in die Phytopathologie. Schwerpunkte: Interaktionen zwischen Pflanzen und pflanzenpathogenen Mikroorganismen, Morphologie und Lebensweise von pflanzenpathogenen Pilzen, Evolution von pflanzenpathogenen Pilzen, biologische Bekämpfung von Pflanzenkrankheiten.

Unterrichtssprache ist Englisch und Deutsch
Skriptwird am Anfang des Blockkurses verteilt
529-0739-01LBiological Chemistry B: New Enzymes from Directed Evolution Experiments Belegung eingeschränkt - Details anzeigen
Number of participants limited to 12.
W6 KP7GP. A. Kast
KurzbeschreibungDuring the block course in the fall semester, we will carry out biological-chemical enzyme evolution experiments using molecular genetic mutation technologies and in vivo selection in recombinant bacterial strains. The class with its very dense program consists of the practical course itself and an integrated series of seminar/lecture sessions.
LernzielAll technologies used for the experiments will be explained to the students in theory and in practice with the goal that they will be able to independently apply them for the course project and in future research endeavors. After the course, an individual report about the results obtained has to be prepared.
InhaltThe class deals with a specifically designed and genuine research project. We intend to carry out biological-chemical enzyme evolution experiments using molecular genetic mutation technologies and in vivo selection in recombinant bacterial strains. By working in parallel, teams of 2 participants each will generate a variety of different variants of a chorismate mutase. Individual enzyme catalysts will be purified and subsequently characterized using several different spectroscopic methods. The detailed chemical-physical analyses include determination of the enzymes' kinetic parameters, their molecular mass, and the integrity of the protein structure. The results obtained from the individual evolution experiments will be compared and discussed at the end of the class in a final seminar. We expect that during this lab course we will not only generate novel enzymes, but also gain new mechanistic insights into the investigated catalyst.
SkriptA script will be distributed to the participants on the first day of the course.
LiteraturGeneral literature to "Directed Evolution" and chorismate mutases, e.g.:

– Taylor, S. V., P. Kast & D. Hilvert. 2001. Investigating and engineering enzymes by genetic selection. Angew. Chem. Int. Ed. 40: 3310-3335.

– Jäckel, C., P. Kast & D. Hilvert. 2008. Protein design by directed evolution. Annu. Rev. Biophys. 37: 153-173.

– Roderer, K. & P. Kast. 2009. Evolutionary cycles for pericyclic reactions – Or why we keep mutating mutases. Chimia 63: 313-317.

Further literature will be indicated in the distributed script.
Voraussetzungen / BesonderesThis laboratory course will involve experiments that require a tight schedule and, particularly in the second half, very long (!) working days. The maximum number of participants for the laboratory class is limited, but surplus applicants may contact P. Kast directly to have their names added to a waiting list. A valid registration is considered a commitment for attendance of the entire course, as involved material orders and experimental preparations are necessary and, once the class has started, the flow of the experiments must not be interrupted by individual absences. In case of an emergency, please immediately notify P. Kast. For more information see Link, from where you can also download a flyer.
551-0336-00LMethods in Cellular Biochemistry Information Belegung eingeschränkt - Details anzeigen
Number of participants limited to 18.

The enrolment is done by the D-BIOL study administration.
W6 KP7GP. Picotti, J. Fernandes de Matos, U. Kutay, M. Peter, K. Weis
KurzbeschreibungStudents will learn about biochemical approaches to analyze cellular functions. The course consists of practical projects in small groups, lectures and literature discussions. The course concludes with the presentation of results at a poster session.
LernzielStudents will learn to design, carry out and assess experiments using current biochemical and cell biological strategies to analyze cellular functions in a wide range of model systems. In particular they will learn novel imaging techniques along with biochemical approaches to understand fundamental cellular pathways. Furthermore, they will learn to assess strengths and limitations of the different approaches and be able to discuss their validity for the analysis of cellular functions.
LiteraturDocumentation and recommended literature (review articles and selected primary literature) will be provided during the course.
Voraussetzungen / BesonderesThis course will be taught in English.
551-1515-00LInsulin Signaling Information Belegung eingeschränkt - Details anzeigen
Number of participants limited to 12.

The enrolment is done by the D-BIOL study administration.
W6 KP7GM. Stoffel
KurzbeschreibungIntroduction to the physiological and biochemical action of insulin signaling and its role in the fasted/feeding response and in obesity and diabetes.
LernzielThe students will obtain an overview about the current topics of research in insulin signaling and how it impacts on growth, metabolism and cell differentiation. They will learn to design experiments and use techniques necessary to analyze different aspects of insulin signaling,including physiological actions in whole animals as well as in tissue culture. Through lectures and literature seminars, they will learn about the open questions of insulin signaling research and discuss approaches to address these questions experimentally.

In practical lab projects the students will perform physiological in vivo studies as well as biochemical experiments. Finally, they will learn how to present and discuss their data. Student assessment is a graded semester performance based on individual performance in the laboratory, a written exam and the lab data presentation.
752-4020-00LExpt. Lebensmittelmikrobiologie für Biologen Belegung eingeschränkt - Details anzeigen
Maximale Teilnehmerzahl: 20

Voraussetzung: Als Vorbereitung für das Praktikum, wird der Besuch der LE Lebensmittel-Mikrobiologie (752-4005-00L) dringend empfohlen.
W6 KP7GM. Schuppler, M. Loessner, M. Schmelcher
KurzbeschreibungVermittlung des praktischen Basiswissens zur Diagnostik von Mikroorganismen in Lebensmitteln. Die vielfältigen Laborexperimente werden durch theoretische Einführungen ergänzt. Der Schwerpunkt liegt auf modernen Methoden der molekularen Diagnostik und dem Schnellnachweis von Krankheitserregern in Lebensmitteln in Anlehnung an aktuelle Forschungsthemen des Labors für Lebensmittelmikrobiologie.
LernzielEinführung in Methodik und Techniken der Lebensmittelmikrobiologie
InhaltVermittlung des praktischen Basiswissens zur mikrobiologischen Untersuchung von Lebensmitteln anhand der Durchführung sowohl klassischer Nachweisverfahren als auch moderner Methoden zur molekularen Diagnostik und zum Schnellnachweis von Krankheitserregern in Lebensmitteln.
SkriptSkripte werden zu Beginn des Praktikums ausgegeben
Literatur- Krämer: "Lebensmittel-Mikrobiologie" (Ulmer; UTB)
- Süssmuth et al.: "Mikrobiologisch-Biochemisches Praktikum" (Thieme)
Voraussetzungen / BesonderesWichtiger Hinweis!
Im Praktikum wird unter anderem mit dem Krankheitserreger Listeria monocytogenes gearbeitet, welcher eine erhebliche Gefährdung für Schwangere darstellt. Aus Gründen der Biosicherheit ist daher eine Teilnahme am Praktikum bei bestehender Schwangerschaft nicht möglich!
551-0363-00LComplex Carbohydrates - Biosynthesis, Structure & Function Information Belegung eingeschränkt - Details anzeigen
Number of participants limited to minimum 2 and maximum 8.

The enrolment is done by the D-BIOL study administration.
W6 KP7GM. Aebi, T. Keys
KurzbeschreibungIn vitro & in vivo Experimente führen in die aktuelle Forschung über Biosynthese, Struktur & Funktion von protein-gebundenen Glykanen in verschiedenen pro- und eukaryotischen Mikroorganismen ein.
LernzielDie Teilnehmer sind vertraut mit der Biosynthese, Struktur und Funktion von N-Glykanen in Mikroorganismen und den Methoden zur Untersuchung derselben.
Inhalt* Themen: Biosynthese von Asparagin-gebundenen Glykanen in Pro- und Eukaryoten; Struktur der Glykane in verschiedenen Organismen; Methoden zur Analyse der Glykanstruktur; Funktion von Glykanen in der Proteinqualitätskontrolle
* Einführende Vorlesungen in die behandelten Themen
* Seminar mit Präsentation und Besprechung aktueller Veröffentlichungen
* Experimente, die Themen aus der aktuellen Forschung der Arbeitsgruppe beispielhaft darstellen
551-0117-00LPlant Volatiles in Plant Insect Interactions Belegung eingeschränkt - Details anzeigen
Findet dieses Semester nicht statt.
Number of participants limited to 16.

The enrolment is done by the D-BIOL study administration.
W6 KP7GC. De Moraes
KurzbeschreibungDuring the course students will become familiar with methods for the collection and analysis of plant-derived volatile organic compounds and explore the role of these compounds in mediating plant-insect interactions.
LernzielThe course will cover six main topics that will be connected throughout the experimental phase:
1) Plant volatile biosynthesis and classification
2) Insect olfactory physiology
3) Volatile-mediated plant-herbivore interactions
4) Volatile-mediated multitrophic interactions
5) Manipulation of plant volatile emission by vector- borne disease agents
6) Methods for volatile collection and analysis
The lab practical will be performed in a system consisting of the cabbage butterfly Pieris brasicae, its host plant Brassica oleracea (Brussels sprouts), and the parasitoid wasp Cotesia glomerata (natural enemy of P. brasicae).
Students will collect volatiles from herbivore-damaged and undamaged plants and learn how to identify and quantify these compounds through gas chromatography coupled with mass spectrometry and flame ionization detection (GG-MS-FID). Afterwards, they will be able to compare volatile emissions from herbivore-damaged and undamaged plants and identify important volatile compounds associated with herbivory. Finally, students will evaluate the effect of herbivore-induced volatile compounds on the behavior of the herbivore (P. brassicae) and its natural enemy (C. glomerata), using different behavioral assays, inculding Y-tube olfactometers and wind tunnels.
SkriptNo script
LiteraturThe recommended literature, including reviews and primary research articles, will be provided during the course.
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