Search result: Catalogue data in Spring Semester 2019

Biology Master Information
Elective Major Subject Areas
Elective Major: Neurosciences
Elective Concept Courses
551-0326-00LCell Biology Information W6 credits4VS. Werner, M. Bordoli, R. Henneberger, W. Kovacs, M. Schäfer, U. Suter, A. Wutz
AbstractThis Course introduces principle concepts, techniques, and experimental strategies used in modern Cell Biology. Major topics include: neuron-glia interactions in health and disease; mitochondrial dynamics; stem cell biology; growth factor action in development, tissue repair and disease; cell metabolism, in particular sensing and signaling mechanisms, cell organelles, and lipid metabolism.
Objective-To prepare the students for successful and efficient lab work by learning how to ask the right questions and to use the appropriate techniques in a research project.
-To convey knowledge about neuron-glia interactions in health and disease.
- To provide information on different types of stem cells and their function in health and disease
-To provide information on growth factor signaling in development, repair and disease and on the use of growth factors or their receptors as drug targets for major human diseases
-To convey knowledge on the mechanisms underlying repair of injured tissues
-To provide the students with an overview of mitochondrial dynamics.
-Providing an understanding of RNA processing reactions and their regulations.
-To provide a comprehensive understanding of metabolic sensing mechanisms occurring in different cell types and organelles in response to glucose, hormones, oxygen, nutrients as well as lipids, and to discuss downstream signaling pathways and cellular responses.
-To provide models explaining how disturbances in complex metabolic control networks and bioenergetics can lead to disease and to highlight latest experimental approaches to uncover the intricacies of metabolic control at the cellular and organismal level.
-Providing the background and context that foster cross-disciplinary scientific thinking.
551-0318-00LImmunology IIW3 credits2VA. Oxenius, M. Kopf, S. R. Leibundgut, E. Wetter Slack, further lecturers
AbstractIntroduction into the cellular and molecular basis of the immune system and immune responses against diverse pathogens, tumors, transplants, and self (autoimmunity)
ObjectiveThe lectures will provide a detailed understanding:
- how innate and adaptive immune responses interact at the cellular and molecular level.
- how the immune system recognizes and fights against pathogenic microorganisms including viruses, bacteria, and parasites.
- why lymphocytes tolerate self molecules.
- about function and dysfunction the intestinal immune system.
- immunopathology and inflammatory diseases.
ContentThe aim of lecture is to understand:
> How pathogens are recognized by the innate immune system
> Immune defense against various pathogens
> Immunology of the skin, lung and intestines
> Tumor immunology
> Migration and homing of immune cells
> tolerance and autoimmunity
> T cell memory
Lecture notesPresentations of the lecturers are available at the Moodle link
LiteratureRecommended: Kuby Immunology (Freeman)
551-0320-00LCellular Biochemistry (Part II)W3 credits2VY. Barral, R. Kroschewski, A. E. Smith
AbstractThis course will focus on molecular mechanisms and concepts underlying cellular biochemistry, providing advanced insights into the structural and functional details of individual cell components, and the complex regulation of their interactions. Particular emphasis will be on the spatial and temporal integration of different molecules and signaling pathways into global cellular processes.
ObjectiveThe full-year course (551-0319-00 & 551-0320-00) focuses on the molecular mechanisms and concepts underlying the biochemistry of cellular physiology, investigating how these processes are integrated to carry out highly coordinated cellular functions. The molecular characterization of complex cellular functions requires a combination of approaches such as biochemistry, but also cell biology and genetics. This course is therefore the occasion to discuss these techniques and their integration in modern cellular biochemistry.
The students will be able to describe the structural and functional details of individual cell components, and the spatial and temporal regulation of their interactions. In particular, they will learn to explain how different molecules and signaling pathways can be integrated during complex and highly dynamic cellular processes such as intracellular transport, cytoskeletal rearrangements, cell motility, and cell division. In addition, they will be able to illustrate the relevance of particular signaling pathways for cellular pathologies such as cancer or during cellular infection.
ContentSpatial and temporal integration of different molecules and signaling pathways into global cellular processes, such as cell division, cell infection and cell motility. Emphasis is also put on the understanding of pathologies associated with defective cell physiology, such as cancer or during cellular infection.
LiteratureRecommended supplementary literature (review articles and selected primary literature) will be provided during the course.
Prerequisites / NoticeTo attend this course the students must have a solid basic knowledge in chemistry, biochemistry, cell biology and general biology. Biology students have in general already attended the first part of the "Cellular Biochemistry" concept course (551-0319-00). The course will be taught in English.
In addition, the course will be based on a blended-learning scenario, where frontal lectures will be complemented with carefully chosen web-based teaching elements that students access through the ETH Moodle platform.
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