Search result: Catalogue data in Autumn Semester 2017
Biology Bachelor | ||||||
2. Year, 3. Semester | ||||||
Core Courses | ||||||
Number | Title | Type | ECTS | Hours | Lecturers | |
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529-1023-00L | Physical Chemistry I (for Biology and Pharmacy) | O | 3 credits | 2V + 1U | R. Riek, H. P. Lüthi | |
Abstract | The laws of thermodynamics: empirical temperature, energy, entropy. Models and standard states: ideal gases, ideal solutions and mixtures, activity, standard thermodynamic values. Reaction thermodynamics: chemical potential, thermodynamic parameters of reactions, equilibrium conditions and their temperature and pressure dependence, biochemical reactions, surface effects, colligative properties. | |||||
Objective | Understanding the fundamental thermodynamic properties of chemical and biological systems. | |||||
Content | The laws of thermodynamics: empirical temperature, energy, entropy. Models and standard states: ideal gases, ideal solutions and mixtures, activity, standard thermodynamic values. Reaction thermodynamics: chemical potential, thermodynamic parameters of reactions, equilibrium conditions and their temperature and pressure dependence, biochemical reactions, surface effects, colligative properties. | |||||
Lecture notes | in process, will be distributed at the beginning of the first lecture | |||||
Literature | 1) Atkins, P.W., 1999, Physical Chemistry, Oxford University Press, 6th ed., 1999. 2) Moore, W.J., 1990: Grundlagen der physikalischen Chemie, W. de Gruyter, Berlin. 3) Adam, G., Läuger, P., Stark, G., 1988: Physikalische Chemie und Biophysik, 2. Aufl., Springer Verlag, Berlin. | |||||
Prerequisites / Notice | Prerequisite: mathematics I+II, functions of multiple variables, partial derivatives. | |||||
551-0103-00L | Fundamentals of Biology II: Cell Biology | O | 5 credits | 5V | E. Hafen, J. Fernandes de Matos, U. Kutay, G. Schertler, U. Suter, S. Werner | |
Abstract | The goal of this course is to provide students with a wide general understanding in cell biology. With this material as a foundation, students have enough of a cell biological basis to begin their specialization not only in cell biology but also in related fields such as biochemistry, microbiology, pharmacological sciences, molecular biology, and others. | |||||
Objective | The goal of this course is to provide students with a wide general understanding cell biology. With this material as a foundation, students have enough of a cell biological basis to begin their specialization not only in cell biology but also in related fields such as biochemistry, microbiology, pharmacological sciences, molecular biology, and others. | |||||
Content | The focus is animal cells and the development of multicellular organisms with a clear emphasis on the molecular basis of cellular structures and phenomena. The topics include biological membranes, the cytoskeleton, protein sorting, energy metabolism, cell cycle and division, viruses, extracellular matrix, cell signaling, embryonic development and cancer research. | |||||
Lecture notes | The lectures are presented in the Powerpoint format. These are available on the WEB for ETH students over the nethz (Moodle). Some lectures are available on the ETH WEB site in a live format (Livestream) at the above WEB site. | |||||
Literature | The lectures follow Alberts et al. `Molecular Biology of the Cell' 6th edition, 2014, ISBN 9780815344322 (hard cover) and ISBN 9780815345244 (paperback). | |||||
Prerequisites / Notice | Some of the lectures are given in the English language. Certain sections of the text-book must be studied by self-instruction. | |||||
551-1323-00L | Fundamentals of Biology II: Biochemistry and Molecular Biology | O | 4 credits | 4V | K. Locher, N. Ban, R. Glockshuber, E. Weber-Ban | |
Abstract | The course provides an introduction to Biochemistry / Molecular Biology with some emphasis on chemical and biophysical aspects. | |||||
Objective | Topics include the structure-function relationship of proteins / nucleic acids, protein folding, enzymatic catalysis, cellular pathways involved in bioenergetics and the biosynthesis and breakdown of amino acids, glycans, nucleotides, fatty acids and phospholipids, and steroids. There will also be a discussion of DNA replication and repair, transcription, and translation. | |||||
Lecture notes | none | |||||
Literature | mandatory: "Biochemistry", Autoren: Berg/Tymoczko/Stryer, 8th edition, Palgrave Macmillan, International edition (the English version will be preordered at the Polybuchhandlung) | |||||
Prerequisites / Notice | Some of the lectures are given in the English language. | |||||
551-1003-00L | Methods of Biological Analysis | O | 3 credits | 3G | R. Aebersold, M. Badertscher, K. Weis | |
Abstract | 529-1042-00 Principles of the most important separation techniques and the interpretation of molecular spectra. 551-1003-00 The course will teach the basis and typical applications of methods for the analysis of nucleic acid sequences, mass spectrometric analysis of proteins and proteomes and advanced light and fluorescent imaging methods. | |||||
Objective | 529-1042-00 Knowledge of the necessary basics and the possibilities of application of the relevant spectroscopical and separation methods in analytical chermistry. 551-1003-00 Knowledge of the theoretical basis of the methods for nucleic acid sequence analysis, mass spectrometry based protein and proteome analysis and advanced light and fluorescent imaging methods, and an understanding of the application of these principles in experimental biology. | |||||
Content | 529-1042-00 Application oriented basics of instrumental analysis in organic chemistry and the empirical employment of the methods of structure elucidation (mass spectrometry, NMR-, IR-, UV/VIS spectroscopy). Basics and application of chromatographic and electrophoretic separation methods. Application of the knowledge by practising. 551-1003-00 The course will consist of lectures covering the theoretical and technical base of the respective analytical methods and of exercises where typical applications of the methods in modern experimental biology are discussed. | |||||
Lecture notes | 529-1042-00 A comprehensive script is available in the HCI-Shop. A summary of the part "Spektroskopie" defines the relevant material for the exam. 551-1003-00 Materials supporting the lectures and exercises will be made available via Moodle. | |||||
Literature | 529-1042-00 - Pretsch E., Bühlmann P., Badertscher M. Structure Determination of Organic Compounds, 5th revised and enlarged English edition, Springer-Verlag, Berlin 2009; - Pretsch E., Bühlmann P., Badertscher M., Spektroskopische Daten zur Strukturaufklärung organischer Verbindungen, fünfte Auflage, Springer-Verlag, Berlin 2010; - D.A. Skoog, J.J. Leary, Instrumentelle Analytik, Grundlagen, Geräte, Anwendungen, Springer, Berlin, 1996; - K. Cammann, Instrumentelle Analytische Chemie, Verfahren, Anwendungen, Qualitätssicherung, Spektrum Akademischer Verlag, Heidelberg, 2001; - R. Kellner, J.-M. Mermet, M. Otto, H.M. Widmer, Analytical Chemistry, Wiley-VCH Verlag, Weinheim, 1998; - K. Robards, P.R.Haddad, P.E. Jackson, Principles and practice of modern chromatographic methods, Academic Press, London, 1994; | |||||
Prerequisites / Notice | 529-1042-00 Prerequisites: - 529-1001-01 V "Allgemeine Chemie I (für Biol./Pharm.Wiss.)" - 529-1001-00 P "Allgemeine Chemie I (für Biol./Pharm.Wiss.)" - 529-1011-00 G "Organische Chemie I (für Biol./Pharm.Wiss.)" | |||||
401-0643-13L | Statistics II | O | 3 credits | 2V + 1U | M. Kalisch | |
Abstract | Vertiefung von Statistikmethoden. Nach dem detailierten Fundament aus Statistik I liegt nun der Fokus auf konzeptueller Breite und konkreter Problemlösungsfähigkeit mit der Statistiksoftware R. | |||||
Objective | Nach diesem Kurs können Sie mit der Statistiksoftware R Daten einlesen, auf vielfältige Art verarbeiten und Grafiken für Berichte oder Vorträge exportieren. Sie verstehen die Konzepte von Methoden wie Lineare Regression (mit Faktoren, Interaktion, Modellwahl), ANOVA (1-weg, 2-weg), Chi-Quadrat-Test, Fisher-Test, GLMs, Mixed Models, Clustering, PCA und können diese mit der Statistiksoftware R in der Praxis umsetzen. Zudem kennen Sie die Grundprinzipien von gutem experimentellem Design und können bestehende Studien kritisch hinterfragen. | |||||
Elective Blocks | ||||||
Biodiversity | ||||||
Number | Title | Type | ECTS | Hours | Lecturers | |
701-0245-00L | Introduction to Evolutionary Biology | O | 2 credits | 2V | G. Velicer, S. Wielgoss | |
Abstract | This course introduces important questions about the evolutionary processes involved in the generation and maintenance of biological diversity across all domains of life and how evolutionary science investigates these questions. | |||||
Objective | This course introduces important questions about the evolutionary processes involved in the generation and maintenance of biological diversity across all domains of life and how evolutionary science investigates these questions. The topics covered range from different forms of selection, phylogenetic analysis, population genetics, life history theory, the evolution of sex, social evolution to human evolution. These topics are important for the understanding of a number of evolutionary problems in the basic and applied sciences. | |||||
Content | Topics likely to be covered in this course include research methods in evolutionary biology, adaptation, evolution of sex, evolutionary transitions, human evolution, infectious disease evolution, life history evolution, macroevolution, mechanisms of evolution, phylogenetic analysis, population dynamics, population genetics, social evolution, speciation and types of selection. | |||||
Literature | Textbook: Evolutionary Analysis Scott Freeman and Jon Herron 5th Edition, English. | |||||
Prerequisites / Notice | The exam is based on lecture and textbook. | |||||
551-0435-00L | Systematic Biology: Zoology | O | 3 credits | 2V + 2P | O. Y. Martin, M. Greeff | |
Abstract | Lecture: The lecture provides an overview of animal diversity. Using key selected groups, phylogenetic, morphological and ecological aspects are addressed. Two priority topics are the arthropods and the vertebrates (including vertebrate fauna of Switzerland). Practical: Knowledge of selected animal groups and their characteristics (supplementing the lecture) and of the basic methods. | |||||
Objective | Lecture: The systematic classification of animals and the characteristics of the most important animal groups, basic animal body plans. Practical: Examples of selected animal groups and their characteristics; acquire the relevant skills: simple preparations, dissection, microscopy, drawing, protocols. | |||||
Content | Lecture: Body plans, characteristics, diversity and phylogenetic position of the main groups of Protozoa, Invertebrates, and Vertebrates, with a special focus on Arthropods and Vertebrates (including vertebrate fauna of Switzerland). Practical: Macroscopic and microscopic study of selected Protozoa, Invertebrates (especially insects) and Vertebrates: morphology and anatomy; behaviour, mainly locomotion, feeding, and reproduction. | |||||
Lecture notes | A script for the course will be sold in the lecture, and additional material will be handed out (particularly in the practical). | |||||
Literature | No further literature required, the script contains suggestions for further reading. | |||||
551-0227-00L | Mycology | O | 2 credits | 2V | M. Künzler | |
Abstract | The lecture gives an introduction into the field of Mycology. It provides an overview of the fungal lifestyle (hyphal growth/mycelium; reproductive cycles; ecology of the fungi; use of fungi). | |||||
Objective | Understanding the fungal life form. Knowledge of the specific properties of the fungal cell Knowledge of the different reproductive cycles in all fungal phyla Knowledge of the different nutritional modes of the fungi; correlation with habitat and ecology Knowledge of the application of fungi in food production and biotechnology | |||||
Content | The lecture focuses on the following topics within Mycology: 1. The fungal lifestyle 2. Differentiation processes of the Mycelium 3. Reproductive cycles and systematic grouping of fungi 4. Ecology of the fungi 5. Use of fungi | |||||
Lecture notes | none; Powerpoint presentation and literature will be provided via Moodle | |||||
Literature | 'Fungal Biology' by Jim Deacon (Blackwell Publishing, 4th Edition, 2006, ISBN-13: 978-1-4051-3066-0) '21st Century Guidebook to Fungi' by David Moore, Geoffrey D. Robson, Anthony P.J. Trinci (Cambridge University Press, 3rd Printing, 2015, ISBN-13: 978-1-107-00676-7 | |||||
Prerequisites / Notice | Lecture starts on Sept. 25 | |||||
Cellular and Molecular Biology | ||||||
Number | Title | Type | ECTS | Hours | Lecturers | |
701-0245-00L | Introduction to Evolutionary Biology | O | 2 credits | 2V | G. Velicer, S. Wielgoss | |
Abstract | This course introduces important questions about the evolutionary processes involved in the generation and maintenance of biological diversity across all domains of life and how evolutionary science investigates these questions. | |||||
Objective | This course introduces important questions about the evolutionary processes involved in the generation and maintenance of biological diversity across all domains of life and how evolutionary science investigates these questions. The topics covered range from different forms of selection, phylogenetic analysis, population genetics, life history theory, the evolution of sex, social evolution to human evolution. These topics are important for the understanding of a number of evolutionary problems in the basic and applied sciences. | |||||
Content | Topics likely to be covered in this course include research methods in evolutionary biology, adaptation, evolution of sex, evolutionary transitions, human evolution, infectious disease evolution, life history evolution, macroevolution, mechanisms of evolution, phylogenetic analysis, population dynamics, population genetics, social evolution, speciation and types of selection. | |||||
Literature | Textbook: Evolutionary Analysis Scott Freeman and Jon Herron 5th Edition, English. | |||||
Prerequisites / Notice | The exam is based on lecture and textbook. | |||||
529-0229-00L | Practical Course Organic Chemistry (for Students of Biology and Pharmaceutical Sciences) Latest online enrolment is 10 days before the beginning of the semester. Students who did not pass the first-year examinations need the lecturers' written permission to take this course. | O | 8 credits | 12P | C. Thilgen, Y. Yamakoshi | |
Abstract | Analytical part: basic operations for the separation of mixtures of organic compounds (recrystallization, distillation, extraction, chromatography) Synthetic part (main part): at least 8 synthetic steps (one- or two-step syntheses). | |||||
Objective | Learn the basic techniques for the preparation and purification of organic compounds. Learn to take accurate notes of the experiments. Deepen the understanding of reaction mechanisms. | |||||
Content | Analytical part: basic operations for the separation of mixtures of organic compounds (recrystallization, distillation, extraction, chromatography). Synthetic part (main part): at least 8 synthetic steps (one- or two-step syntheses). Introduction to database searches (Reaxys, SciFinder). | |||||
Lecture notes | Documentation will be handed out at the beginning of the course. | |||||
Literature | 1) P. Wörfel, M. Bitzer, U. Claus, H. Felber, M. Hübel, B. Vollenweider, Laborpraxis (Bd. 1: Einführung, allgemeine Methoden; Bd. 2: Messmethoden; Bd. 3: Trennungsmethoden; Bd. 4: Analytische Methoden), Birkhäuser Verlag. 2) J. Leonard, B. Lygo, G. Procter, Advanced Practical Organic Chemistry, Blackie Ltd., Glasgow, 1995. (Advanced level). | |||||
Prerequisites / Notice | The basic reactions of Organic Chemistry and their mechanisms should be known (cf. course 529-1012-00L Organic Chemistry II for Students of Biology, Pharmaceutical Sciences, and Health Sci. and Tech.). As a prerequisite, all participants need to pass the "Safety Test HCI Chemie_V2 English" (see Link). A printout of the certificate generated by the system needs to be presented to the teaching assistants prior to starting lab work. | |||||
Biological Chemistry | ||||||
Number | Title | Type | ECTS | Hours | Lecturers | |
529-0229-00L | Practical Course Organic Chemistry (for Students of Biology and Pharmaceutical Sciences) Latest online enrolment is 10 days before the beginning of the semester. Students who did not pass the first-year examinations need the lecturers' written permission to take this course. | O | 8 credits | 12P | C. Thilgen, Y. Yamakoshi | |
Abstract | Analytical part: basic operations for the separation of mixtures of organic compounds (recrystallization, distillation, extraction, chromatography) Synthetic part (main part): at least 8 synthetic steps (one- or two-step syntheses). | |||||
Objective | Learn the basic techniques for the preparation and purification of organic compounds. Learn to take accurate notes of the experiments. Deepen the understanding of reaction mechanisms. | |||||
Content | Analytical part: basic operations for the separation of mixtures of organic compounds (recrystallization, distillation, extraction, chromatography). Synthetic part (main part): at least 8 synthetic steps (one- or two-step syntheses). Introduction to database searches (Reaxys, SciFinder). | |||||
Lecture notes | Documentation will be handed out at the beginning of the course. | |||||
Literature | 1) P. Wörfel, M. Bitzer, U. Claus, H. Felber, M. Hübel, B. Vollenweider, Laborpraxis (Bd. 1: Einführung, allgemeine Methoden; Bd. 2: Messmethoden; Bd. 3: Trennungsmethoden; Bd. 4: Analytische Methoden), Birkhäuser Verlag. 2) J. Leonard, B. Lygo, G. Procter, Advanced Practical Organic Chemistry, Blackie Ltd., Glasgow, 1995. (Advanced level). | |||||
Prerequisites / Notice | The basic reactions of Organic Chemistry and their mechanisms should be known (cf. course 529-1012-00L Organic Chemistry II for Students of Biology, Pharmaceutical Sciences, and Health Sci. and Tech.). As a prerequisite, all participants need to pass the "Safety Test HCI Chemie_V2 English" (see Link). A printout of the certificate generated by the system needs to be presented to the teaching assistants prior to starting lab work. | |||||
529-1121-00L | Inorganic Chemistry (for Biology) | O | 3 credits | 2V + 1U | A. Mezzetti, A. Fedorov | |
Abstract | Orbitals and chemical bonding in main-group elements and transition metals. | |||||
Objective | Introduction to the orbital concept and to the binding theory in complexes of the transition metals. | |||||
Content | The origin of quantum theory. The hydrogen atom. Polyelectronic atoms and the periodic table. Orbitals and small molecules. Symmetry and group theory. Chemical bonding in transition metal complexes (Valence Bond Theory, Crystal Field Theory, Molecular Orbital Theory (sigma- and pi-bonding). pi-Accepting ligands. | |||||
Lecture notes | Can be bought at the HCI-shop. | |||||
Literature | - J. E. Huheey: Anorganische Chemie, Prinzipien von Struktur und Reaktivität, Walter de Gruyter, Berlin, 3. Auflage, 2003. |
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