Search result: Catalogue data in Autumn Semester 2017

Biology Bachelor Information
2. Year, 3. Semester
Core Courses
NumberTitleTypeECTSHoursLecturers
529-1023-00LPhysical Chemistry I (for Biology and Pharmacy)O3 credits2V + 1UR. Riek, H. P. Lüthi
AbstractThe laws of thermodynamics: empirical temperature, energy, entropy. Models and standard states: ideal gases, ideal solutions and mixtures, activity, standard thermodynamic values. Reaction thermodynamics: chemical potential, thermodynamic parameters of reactions, equilibrium conditions and their temperature and pressure dependence, biochemical reactions, surface effects, colligative properties.
ObjectiveUnderstanding the fundamental thermodynamic properties of chemical and biological systems.
ContentThe laws of thermodynamics: empirical temperature, energy, entropy. Models and standard states: ideal gases, ideal solutions and mixtures, activity, standard thermodynamic values. Reaction thermodynamics: chemical potential, thermodynamic parameters of reactions, equilibrium conditions and their temperature and pressure dependence, biochemical reactions, surface effects, colligative properties.
Lecture notesin process, will be distributed at the beginning of the first lecture
Literature1) Atkins, P.W., 1999, Physical Chemistry, Oxford University Press, 6th ed., 1999.
2) Moore, W.J., 1990: Grundlagen der physikalischen Chemie, W. de Gruyter, Berlin.
3) Adam, G., Läuger, P., Stark, G., 1988: Physikalische Chemie und Biophysik, 2. Aufl., Springer Verlag, Berlin.
Prerequisites / NoticePrerequisite: mathematics I+II, functions of multiple variables, partial derivatives.
551-0103-00LFundamentals of Biology II: Cell BiologyO5 credits5VE. Hafen, J. Fernandes de Matos, U. Kutay, G. Schertler, U. Suter, S. Werner
AbstractThe goal of this course is to provide students with a wide general understanding in cell biology. With this material as a foundation, students have enough of a cell biological basis to begin their specialization not only in cell biology but also in related fields such as biochemistry, microbiology, pharmacological sciences, molecular biology, and others.
ObjectiveThe goal of this course is to provide students with a wide general understanding cell biology. With this material as a foundation, students have enough of a cell biological basis to begin their specialization not only in cell biology but also in related fields such as biochemistry, microbiology, pharmacological sciences, molecular biology, and others.
ContentThe focus is animal cells and the development of multicellular organisms with a clear emphasis on the molecular basis of cellular structures and phenomena. The topics include biological membranes, the cytoskeleton, protein sorting, energy metabolism, cell cycle and division, viruses, extracellular matrix, cell signaling, embryonic development and cancer research.
Lecture notesThe lectures are presented in the Powerpoint format. These are available on the WEB for ETH students over the nethz (Moodle). Some lectures are available on the ETH WEB site in a live format (Livestream) at the above WEB site.
LiteratureThe lectures follow Alberts et al. `Molecular Biology of the Cell' 6th edition, 2014, ISBN 9780815344322 (hard cover) and ISBN 9780815345244
(paperback).
Prerequisites / NoticeSome of the lectures are given in the English language. Certain sections of the text-book must be studied by self-instruction.
551-1323-00LFundamentals of Biology II: Biochemistry and Molecular Biology Information O4 credits4VK. Locher, N. Ban, R. Glockshuber, E. Weber-Ban
AbstractThe course provides an introduction to Biochemistry / Molecular Biology with some emphasis on chemical and biophysical aspects.
ObjectiveTopics include the structure-function
relationship of proteins / nucleic acids, protein folding, enzymatic catalysis, cellular pathways involved in bioenergetics and the biosynthesis and breakdown of amino acids, glycans, nucleotides, fatty acids and phospholipids, and steroids. There will also be a discussion of DNA replication and repair, transcription, and translation.
Lecture notesnone
Literaturemandatory: "Biochemistry",
Autoren: Berg/Tymoczko/Stryer, 8th edition, Palgrave Macmillan, International edition (the English version will be preordered at the Polybuchhandlung)
Prerequisites / NoticeSome of the lectures are given in the English language.
551-1003-00LMethods of Biological Analysis Information O3 credits3GR. Aebersold, M. Badertscher, K. Weis
Abstract529-1042-00
Principles of the most important separation techniques and the interpretation of molecular spectra.

551-1003-00
The course will teach the basis and typical applications of methods for the analysis of nucleic acid sequences, mass spectrometric analysis of proteins and proteomes and advanced light and fluorescent imaging methods.
Objective529-1042-00
Knowledge of the necessary basics and the possibilities of application of the relevant spectroscopical and separation methods in analytical chermistry.

551-1003-00
Knowledge of the theoretical basis of the methods for nucleic acid sequence analysis, mass spectrometry based protein and proteome analysis and advanced light and fluorescent imaging methods, and an understanding of the application of these principles in experimental biology.
Content529-1042-00
Application oriented basics of instrumental analysis in organic chemistry and the empirical employment of the methods of structure elucidation (mass spectrometry, NMR-, IR-, UV/VIS spectroscopy). Basics and application of chromatographic and electrophoretic separation methods. Application of the knowledge by practising.

551-1003-00
The course will consist of lectures covering the theoretical and technical base of the respective analytical methods and of exercises where typical applications of the methods in modern experimental biology are discussed.
Lecture notes529-1042-00
A comprehensive script is available in the HCI-Shop. A summary of the part "Spektroskopie" defines the relevant material for the exam.

551-1003-00
Materials supporting the lectures and exercises will be made available via Moodle.
Literature529-1042-00
- Pretsch E., Bühlmann P., Badertscher M. Structure Determination of Organic Compounds, 5th revised and enlarged English edition, Springer-Verlag, Berlin 2009;
- Pretsch E., Bühlmann P., Badertscher M., Spektroskopische Daten zur Strukturaufklärung organischer Verbindungen, fünfte Auflage, Springer-Verlag, Berlin 2010;
- D.A. Skoog, J.J. Leary, Instrumentelle Analytik, Grundlagen, Geräte, Anwendungen, Springer, Berlin, 1996;
- K. Cammann, Instrumentelle Analytische Chemie, Verfahren, Anwendungen, Qualitätssicherung, Spektrum Akademischer Verlag, Heidelberg, 2001;
- R. Kellner, J.-M. Mermet, M. Otto, H.M. Widmer, Analytical Chemistry, Wiley-VCH Verlag, Weinheim, 1998;
- K. Robards, P.R.Haddad, P.E. Jackson, Principles and practice of modern chromatographic methods, Academic Press, London, 1994;
Prerequisites / Notice529-1042-00
Prerequisites:
- 529-1001-01 V "Allgemeine Chemie I (für Biol./Pharm.Wiss.)"
- 529-1001-00 P "Allgemeine Chemie I (für Biol./Pharm.Wiss.)"
- 529-1011-00 G "Organische Chemie I (für Biol./Pharm.Wiss.)"
401-0643-13LStatistics IIO3 credits2V + 1UM. Kalisch
AbstractVertiefung von Statistikmethoden. Nach dem detailierten Fundament aus Statistik I liegt nun der Fokus auf konzeptueller Breite und konkreter Problemlösungsfähigkeit mit der Statistiksoftware R.
ObjectiveNach diesem Kurs können Sie mit der Statistiksoftware R Daten einlesen, auf vielfältige Art verarbeiten und Grafiken für Berichte oder Vorträge exportieren. Sie verstehen die Konzepte von Methoden wie Lineare Regression (mit Faktoren, Interaktion, Modellwahl), ANOVA (1-weg, 2-weg), Chi-Quadrat-Test, Fisher-Test, GLMs, Mixed Models, Clustering, PCA und können diese mit der Statistiksoftware R in der Praxis umsetzen. Zudem kennen Sie die Grundprinzipien von gutem experimentellem Design und können bestehende Studien kritisch hinterfragen.
Elective Blocks
Biodiversity
NumberTitleTypeECTSHoursLecturers
701-0245-00LIntroduction to Evolutionary BiologyO2 credits2VG. Velicer, S. Wielgoss
AbstractThis course introduces important questions about the evolutionary processes involved in the generation and maintenance of biological diversity across all domains of life and how evolutionary science investigates these questions.
ObjectiveThis course introduces important questions about the evolutionary processes involved in the generation and maintenance of biological diversity across all domains of life and how evolutionary science investigates these questions. The topics covered range from different forms of selection, phylogenetic analysis, population genetics, life history theory, the evolution of sex, social evolution to human evolution. These topics are important for the understanding of a number of evolutionary problems in the basic and applied sciences.
ContentTopics likely to be covered in this course include research methods in evolutionary biology, adaptation, evolution of sex, evolutionary transitions, human evolution, infectious disease evolution, life history evolution, macroevolution, mechanisms of evolution, phylogenetic analysis, population dynamics, population genetics, social evolution, speciation and types of selection.
LiteratureTextbook:
Evolutionary Analysis
Scott Freeman and Jon Herron
5th Edition, English.
Prerequisites / NoticeThe exam is based on lecture and textbook.
551-0435-00LSystematic Biology: Zoology Restricted registration - show details O3 credits2V + 2PO. Y. Martin, M. Greeff
AbstractLecture: The lecture provides an overview of animal diversity. Using key selected groups, phylogenetic, morphological and ecological aspects are addressed. Two priority topics are the arthropods and the vertebrates (including vertebrate fauna of Switzerland).

Practical: Knowledge of selected animal groups and their characteristics (supplementing the lecture) and of the basic methods.
ObjectiveLecture: The systematic classification of animals and the characteristics of the most important animal groups, basic animal body plans.

Practical: Examples of selected animal groups and their characteristics; acquire the relevant skills: simple preparations, dissection, microscopy, drawing, protocols.
ContentLecture: Body plans, characteristics, diversity and phylogenetic position of the main groups of Protozoa, Invertebrates, and Vertebrates, with a special focus on Arthropods and Vertebrates (including vertebrate fauna of Switzerland).

Practical: Macroscopic and microscopic study of selected Protozoa, Invertebrates (especially insects) and Vertebrates: morphology and anatomy; behaviour, mainly locomotion, feeding, and reproduction.
Lecture notesA script for the course will be sold in the lecture, and additional material will be handed out (particularly in the practical).
LiteratureNo further literature required, the script contains suggestions for further reading.
551-0227-00LMycologyO2 credits2VM. Künzler
AbstractThe lecture gives an introduction into the field of Mycology. It provides an overview of the fungal lifestyle (hyphal growth/mycelium; reproductive cycles; ecology of the fungi; use of fungi).
ObjectiveUnderstanding the fungal life form.
Knowledge of the specific properties of the fungal cell
Knowledge of the different reproductive cycles in all fungal phyla
Knowledge of the different nutritional modes of the fungi; correlation with habitat and ecology
Knowledge of the application of fungi in food production and biotechnology
ContentThe lecture focuses on the following topics within Mycology:
1. The fungal lifestyle
2. Differentiation processes of the Mycelium
3. Reproductive cycles and systematic grouping of fungi
4. Ecology of the fungi
5. Use of fungi
Lecture notesnone; Powerpoint presentation and literature will be provided via Moodle
Literature'Fungal Biology' by Jim Deacon (Blackwell Publishing, 4th Edition, 2006, ISBN-13: 978-1-4051-3066-0)

'21st Century Guidebook to Fungi' by David Moore, Geoffrey D. Robson, Anthony P.J. Trinci (Cambridge University Press, 3rd Printing, 2015, ISBN-13: 978-1-107-00676-7
Prerequisites / NoticeLecture starts on Sept. 25
Cellular and Molecular Biology
NumberTitleTypeECTSHoursLecturers
701-0245-00LIntroduction to Evolutionary BiologyO2 credits2VG. Velicer, S. Wielgoss
AbstractThis course introduces important questions about the evolutionary processes involved in the generation and maintenance of biological diversity across all domains of life and how evolutionary science investigates these questions.
ObjectiveThis course introduces important questions about the evolutionary processes involved in the generation and maintenance of biological diversity across all domains of life and how evolutionary science investigates these questions. The topics covered range from different forms of selection, phylogenetic analysis, population genetics, life history theory, the evolution of sex, social evolution to human evolution. These topics are important for the understanding of a number of evolutionary problems in the basic and applied sciences.
ContentTopics likely to be covered in this course include research methods in evolutionary biology, adaptation, evolution of sex, evolutionary transitions, human evolution, infectious disease evolution, life history evolution, macroevolution, mechanisms of evolution, phylogenetic analysis, population dynamics, population genetics, social evolution, speciation and types of selection.
LiteratureTextbook:
Evolutionary Analysis
Scott Freeman and Jon Herron
5th Edition, English.
Prerequisites / NoticeThe exam is based on lecture and textbook.
529-0229-00LPractical Course Organic Chemistry (for Students of Biology and Pharmaceutical Sciences) Restricted registration - show details
Latest online enrolment is 10 days before the beginning of the semester.
Students who did not pass the first-year examinations need the lecturers' written permission to take this course.
O8 credits12PC. Thilgen, Y. Yamakoshi
AbstractAnalytical part: basic operations for the separation of mixtures of organic compounds (recrystallization, distillation, extraction, chromatography)
Synthetic part (main part): at least 8 synthetic steps (one- or two-step syntheses).
ObjectiveLearn the basic techniques for the preparation and purification of organic compounds.
Learn to take accurate notes of the experiments.
Deepen the understanding of reaction mechanisms.
ContentAnalytical part: basic operations for the separation of mixtures of organic compounds (recrystallization, distillation, extraction, chromatography).
Synthetic part (main part): at least 8 synthetic steps (one- or two-step syntheses).
Introduction to database searches (Reaxys, SciFinder).
Lecture notesDocumentation will be handed out at the beginning of the course.
Literature1) P. Wörfel, M. Bitzer, U. Claus, H. Felber, M. Hübel, B. Vollenweider, Laborpraxis (Bd. 1: Einführung, allgemeine Methoden; Bd. 2: Messmethoden; Bd. 3: Trennungsmethoden; Bd. 4: Analytische Methoden), Birkhäuser Verlag.
2) J. Leonard, B. Lygo, G. Procter, Advanced Practical Organic Chemistry, Blackie Ltd., Glasgow, 1995. (Advanced level).
Prerequisites / NoticeThe basic reactions of Organic Chemistry and their mechanisms should be known (cf. course 529-1012-00L Organic Chemistry II for Students of Biology, Pharmaceutical Sciences, and Health Sci. and Tech.).

As a prerequisite, all participants need to pass the "Safety Test HCI Chemie_V2 English" (see Link). A printout of the certificate generated by the system needs to be presented to the teaching assistants prior to starting lab work.
Biological Chemistry
NumberTitleTypeECTSHoursLecturers
529-0229-00LPractical Course Organic Chemistry (for Students of Biology and Pharmaceutical Sciences) Restricted registration - show details
Latest online enrolment is 10 days before the beginning of the semester.
Students who did not pass the first-year examinations need the lecturers' written permission to take this course.
O8 credits12PC. Thilgen, Y. Yamakoshi
AbstractAnalytical part: basic operations for the separation of mixtures of organic compounds (recrystallization, distillation, extraction, chromatography)
Synthetic part (main part): at least 8 synthetic steps (one- or two-step syntheses).
ObjectiveLearn the basic techniques for the preparation and purification of organic compounds.
Learn to take accurate notes of the experiments.
Deepen the understanding of reaction mechanisms.
ContentAnalytical part: basic operations for the separation of mixtures of organic compounds (recrystallization, distillation, extraction, chromatography).
Synthetic part (main part): at least 8 synthetic steps (one- or two-step syntheses).
Introduction to database searches (Reaxys, SciFinder).
Lecture notesDocumentation will be handed out at the beginning of the course.
Literature1) P. Wörfel, M. Bitzer, U. Claus, H. Felber, M. Hübel, B. Vollenweider, Laborpraxis (Bd. 1: Einführung, allgemeine Methoden; Bd. 2: Messmethoden; Bd. 3: Trennungsmethoden; Bd. 4: Analytische Methoden), Birkhäuser Verlag.
2) J. Leonard, B. Lygo, G. Procter, Advanced Practical Organic Chemistry, Blackie Ltd., Glasgow, 1995. (Advanced level).
Prerequisites / NoticeThe basic reactions of Organic Chemistry and their mechanisms should be known (cf. course 529-1012-00L Organic Chemistry II for Students of Biology, Pharmaceutical Sciences, and Health Sci. and Tech.).

As a prerequisite, all participants need to pass the "Safety Test HCI Chemie_V2 English" (see Link). A printout of the certificate generated by the system needs to be presented to the teaching assistants prior to starting lab work.
529-1121-00LInorganic Chemistry (for Biology) Information O3 credits2V + 1UA. Mezzetti, A. Fedorov
AbstractOrbitals and chemical bonding in main-group elements and transition metals.
ObjectiveIntroduction to the orbital concept and to the binding theory in complexes of the transition metals.
ContentThe origin of quantum theory. The hydrogen atom. Polyelectronic atoms and the periodic table. Orbitals and small molecules. Symmetry and group theory. Chemical bonding in transition metal complexes (Valence Bond Theory, Crystal Field Theory, Molecular Orbital Theory (sigma- and pi-bonding). pi-Accepting ligands.
Lecture notesCan be bought at the HCI-shop.
Literature- J. E. Huheey: Anorganische Chemie, Prinzipien von Struktur und Reaktivität, Walter de Gruyter, Berlin, 3. Auflage, 2003.
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