Search result: Catalogue data in Autumn Semester 2017

Health Sciences and Technology Bachelor Information
Electives
NumberTitleTypeECTSHoursLecturers
151-0255-00LEnergy Conversion and Transport in BiosystemsW4 credits2V + 1UA. Ferrari
AbstractTheory and application of thermodynamics and energy conversion in biological systems with focus on the cellular level.
ObjectiveTheory and application of energy conversion at the cellular level. Understanding of the basic features governing solutes transport in the principal systems of the human cell. Connection of characteristics and patterns from other fields of engineering to biofluidics. Heat and mass transport processes in the cell, generation of forces, work and relation to biomedical technologies.
ContentMass transfer models for the transport of chemical species in the human cell. Organization and function of the cell membrane and of the cell cytoskeleton. The role of molecular motors in cellular force generation and their function in cell migration. Description of the functionality of these systems and of analytical experimental and computational techniques for understanding of their operation. Introduction to cell metabolism, cellular energy transport and cellular thermodynamics.
Lecture notesMaterial in the form of hand-outs will be distributed.
LiteratureLecture notes and references therein.
151-0575-01LSignals and Systems Information W4 credits2V + 2UR. D'Andrea
AbstractSignals arise in most engineering applications. They contain information about the behavior of physical systems. Systems respond to signals and produce other signals. In this course, we explore how signals can be represented and manipulated, and their effects on systems. We further explore how we can discover basic system properties by exciting a system with various types of signals.
ObjectiveMaster the basics of signals and systems. Apply this knowledge to problems in the homework assignments and programming exercise.
ContentDiscrete-time signals and systems. Fourier- and z-Transforms. Frequency domain characterization of signals and systems. System identification. Time series analysis. Filter design.
Lecture notesLecture notes available on course website.
Prerequisites / NoticeControl Systems I is helpful but not required.
151-0604-00LMicrorobotics Information W4 credits3GB. Nelson
AbstractMicrorobotics is an interdisciplinary field that combines aspects of robotics, micro and nanotechnology, biomedical engineering, and materials science. The aim of this course is to expose students to the fundamentals of this emerging field. Throughout the course students are expected to submit assignments. The course concludes with an end-of-semester examination.
ObjectiveThe objective of this course is to expose students to the fundamental aspects of the emerging field of microrobotics. This includes a focus on physical laws that predominate at the microscale, technologies for fabricating small devices, bio-inspired design, and applications of the field.
ContentMain topics of the course include:
- Scaling laws at micro/nano scales
- Electrostatics
- Electromagnetism
- Low Reynolds number flows
- Observation tools
- Materials and fabrication methods
- Applications of biomedical microrobots
Lecture notesThe powerpoint slides presented in the lectures will be mad available as pdf files. Several readings will also be made available electronically.
Prerequisites / NoticeThe lecture will be taught in English.
151-0917-00LMass TransferW4 credits2V + 2UR. Büchel, K. Wegner, M. Eggersdorfer
AbstractThis course presents the fundamentals of transport phenomena with emphasis on mass transfer. The physical significance of basic principles is elucidated and quantitatively described. Furthermore the application of these principles to important engineering problems is demonstrated.
ObjectiveThis course presents the fundamentals of transport phenomena with emphasis on mass transfer. The physical significance of basic principles is elucidated and quantitatively described. Furthermore the application of these principles to important engineering problems is demonstrated.
ContentFick's laws; application and significance of mass transfer; comparison of Fick's laws with Newton's and Fourier's laws; derivation of Fick's 2nd law; diffusion in dilute and concentrated solutions; rotating disk; dispersion; diffusion coefficients, viscosity and heat conduction (Pr and Sc numbers); Brownian motion; Stokes-Einstein equation; mass transfer coefficients (Nu and Sh numbers); mass transfer across interfaces; Reynolds- and Chilton-Colburn analogies for mass-, heat-, and momentum transfer in turbulent flows; film-, penetration-, and surface renewal theories; simultaneous mass, heat and momentum transfer (boundary layers); homogenous and heterogenous reversible and irreversible reactions; diffusion-controlled reactions; mass transfer and first order heterogenous reaction. Applications.
LiteratureCussler, E.L.: "Diffusion", 3nd edition, Cambridge University Press, 2009.
Prerequisites / NoticeTwo tests are offered for practicing the course material. Participation is mandatory.
227-0045-00LSignals and Systems IW4 credits2V + 2UH. Bölcskei
AbstractSignal theory and systems theory (continuous-time and discrete-time): Signal analysis in the time and frequency domains, signal spaces, Hilbert spaces, generalized functions, linear time-invariant systems, sampling theorems, discrete-time signals and systems, digital filter structures, Discrete Fourier Transform (DFT), finite-dimensional signals and systems, Fast Fourier Transform (FFT).
ObjectiveIntroduction to mathematical signal processing and system theory.
ContentSignal theory and systems theory (continuous-time and discrete-time): Signal analysis in the time and frequency domains, signal spaces, Hilbert spaces, generalized functions, linear time-invariant systems, sampling theorems, discrete-time signals and systems, digital filter structures, Discrete Fourier Transform (DFT), finite-dimensional signals and systems, Fast Fourier Transform (FFT).
Lecture notesLecture notes, problem set with solutions.
327-0103-00LIntroduction to Materials ScienceW3 credits3GM. Niederberger, L. Heyderman, N. Spencer, P. Uggowitzer
AbstractFundamental knowledge and understanding of the atomistic and macroscopic concepts of material science.
ObjectiveBasic concepts in materials science.
ContentContents:
Atomic structure
Atomic bonds
Crystalline structure, perfection - imperfection
Diffusion
Mechanical and thermal properties
Phase diagrams
Kinetics
Structural materials
Electric, magnetic and optical properties of materials
Surfaces
Materials selection criteria
Lecture notesLink
LiteratureJames F. Shackelford
Introduction to Materials Science for Engineers
5th Ed., Prentice Hall, New Jersey, 2000
376-0130-00LLaboratory Course in Exercise Physiology Information Restricted registration - show details
Number of participants limited to 48.

HST: Possible from the 5th semester on,
W3 credits4PC. Spengler
AbstractConduct physical performance tests and measurements that are typically used to assess performance of athletes and/or patients and that deepen the understanding of physiological processes in response to physical exertion.
ObjectiveGain hands-on experience in exercise physiology and consolidate knowledge on physiological adaptations to different types and degrees of physical activity and climatic influences. Learn fundamental assessment techniques of the muscular system, the cardio-respiratory system and of whole-body performance, learn scientifically correct data analysis and interpretation of results. Insight into today's Sports Medicine.
ContentLaboratory course:
Various exercise tests assessing human performance and assessments of physiological responses to activity (examples are VO2max-test, Conconi-Tests, Determination of anaerobic threshold, Cooper-Test, 1-repetition maximum test, lactate minimum test), dynamometry, mechanography, body composition etc.). Insight into measurements in Sports Medicine.
Lecture notesTutorial on Laboratory Experiments in Exercise Physiology
(Editor: Exercise Physiology Lab)
LiteratureSchmidt/Lang/Heckmann: Physiologie des Menschen, Springer-Verlag, Heidelberg

Kenney/Wilmore/Costill: Physiology of Sport and Exercise, Human Kinetics
Prerequisites / NoticePrerequisite:
Anatomy and physiology classes and lab course in physiology successfully completed (BWS students please contact C. M. Spengler)

Desirable:
Exercise Physiology Lecture (concomitantly or passed; is selection criterion in case of more applications than lab spaces)
376-1033-00LHistory of SportsW2 credits2VM. Gisler
AbstractComprehension for development and changes of sports from the ancient world to the presence. Description of sports in services of national idea, from education and health promotion from the middle of the 18th century till this day.
ObjectiveUnderstanding for the development and adaptation of sports from the ancient world to present times.
ContentKurzüberblick über Antike bis frühe Neuzeit. Darstellung des Sports im Dienst nationaler Ideen, von Bildung und Erziehung, der Gesundheitsförderung von der Mitte des 18. Jahrhunderts bis heute.Überblick über die Geschichte der Olympischen Spiele in der Antike und Gegenwart.
Lecture notesEin Skript für die aktuelle Veranstaltung wird abgegeben.
LiteratureLiteraturangaben für eine Vertiefung der Inhalte werden im Skript gemacht. Die Anschaffung von Spezialliteratur ist allerdings nicht notwendig.
376-1107-00LSport PedagogyW2 credits2VM. Wagner
AbstractThe teacher-student interaction presents a complex psychosocial event, demonstrating the need for a psychological extension of the classical social science / sports pedagogical perspective. Therefore, this lecture will be focused on "pedagogical-psychological aspects of competence development in the context of a multi-perspective physical education".
ObjectiveDevelopment of pedagogical-psychological competences for the optimisation of future teaching activities.
Content- Gegenstandsbereich der pädagogischen Psychologie
- Schüler im Sportunterricht motivieren
- Selbstwirksamkeit aufbauen und das Selbstkonzept stärken
- Positive Emotionen und einen positiven Umgang mit Angst fördern
- Selbstgesteuertes Lernen anregen
- Klassen führen und Kooperation fördern
- Effizient mit Schülern kommunizieren
- Eigene Erwartungen kritisch reflektieren
- Mit Geschlechterfragen sensibel umgehen
- Inklusion fördern / Soziale und moralische Entwicklung stärken
- Mit schwierigen Schülern umgehen
- Leistungen von Schülern bewerten
Lecture notesUnterrichtsmaterialien zu den einzelnen Veranstaltungen werden den Studierenden über moodle zur Verfügung gestellt.
LiteraturePrimärliteratur:
Gerber, M. (2014). Pädagogische Psychologie im Sportunterricht. Ein Lehrbuch in 14 Lektionen. Aachen: Meyer & Meyer Verlag.
376-1117-00LSport PsychologyW2 credits2VH. Gubelmann
AbstractThis lecture is intended as an introduction to sport psychology and imparts knowledge on selected areas of the subject.
ObjectiveStudents are given insight into different work areas of sport psychology. In order to understand what «sport psychology» is, it is necessary to explain the essence and tasks of sport psychology and what it relates to, and to work out an underlying basis for key topics, such as cognition and emotions. Students' expertise is furthered by presenting and providing more in-depth treatment of additional topics of sport psychology. Selected intervention forms are intended to provide insight into applied sport psychology and ensure that mental processes and their impact in sport can be recognised. Case studies and practical exercises (e.g. objective training) are intended to prompt students to reflect to a greater extent on the forms in which sport psychology can be applied in their practice of sports and to integrate these in their teaching.
ContentMain Topics
- Introduction to sport psychology
- Cognitions in sports: mental rehearsal and mental training
- Emotions and stress
- Motivation: goal-setting in sports
- Career and career transition in elite sport
- Coach-Athlete-Interaction
- Psychological aspects of sport-injury rehabilitation
- Group dynamics in sport
Lecture notesUnterrichtsmaterialien zu den einzelnen Veranstaltungen werden den Studierenden zur Verfügung gestellt.
LiteraturePflichtlektüre: Alfermann, D. & Stoll, O. (2010). Sportpsychologie: Ein Lehrbuch in 12 Lektionen. (3. Aufl.), Aachen u.a.: Meyer & Meyer.

Empfohlen: Gerrig, J.P. (2014). Psychologie. (20. Aufl.), München u.a.: Pearson.
376-1121-00LSocio-Scientific Health Research: A Thematic Insight and Overview Restricted registration - show details
Only for Health Sciences and Technology BSc
Number of participants limited to 24
W2 credits2GO. Hämmig, S. T. Güntert, M. Knecht-Meier
AbstractPresentation of and work with different topics and particularly relevent focal points of socio-scientific health research as well as communication of contents and becoming more familiar with ways of thinking and working in socio-scientific health research.
ObjectiveThe students get to know important and particularly health relevant socio-scientific topics, phenomena and problems and learn how to handle related issues and questions.
ContentThere are many different socio-scientific disciplines or rather subdisciplines which deal with health relevant topics such as social or health psychology, medical or health sociology, gerontology, health economics, social epidemiology etc. They all belong to the health sciences and address societal and individual causes and conditions of health and disease. These causes and conditions include experiences such as social integration or isolation, poverty, migration, violence, social deprivation and discriminiation, lifestyle, socialisation and family, personality, profession, unemployment, but also psychosocial aspects of biological characteristics like sex or age. The course gives an insight and overview of these social and personal determinants of health, which turned out to be highly relevant with regard to health, disease, life quality and mortality or life expectancy.
Prerequisites / NoticeWillingness to be regularly present and to play an active part in the course.
376-1127-00LSociology of SportW2 credits2VM. Lamprecht
AbstractThese lectures deal with the current changes in society and sport and provide an overview of the many different problems and perspectives of sport sociology.
ObjectiveThe lectures set out to:
- present the different dimensions, functions and interrelationships of present-day sport
- provide an introduction to the central theories and models of (sport) sociology
- show how far sport reflects society and how it changes and becomes more differentiated in the process
- take current examples from newspapers, magazines and television to highlight the sociological view of sport.
Content• Sport and social change: developments and trends
• The economy and the media: dependencies, consequences, scandals
• Social inequalities and distinctions: gender differences and group behavior
• Conflicts and politics: sports organizations, doping, violence
Lecture notesSelected materials for the lecture are available under Link --> Lehre
Literature- Coakley, Jay und Elizabeth Pike (2009): Sport in Society: Issues and Controversies. New York: Mc.Graw-Hill.
- Lamprecht, Markus und Hanspeter Stamm (2002): Sport zwischen Kultur, Kult und Kommerz. Zürich: Seismo.
- Thiel Ansgar, Klaus Seiberth und Jochen Mayer (2013): Sportsoziologie: Ein Lehrbuch in 13 Lektionen. Aachen: Meyer & Meyer.
- Weis, Kurt und Robert Gugutzer (Hg.) (2008): Handbuch Sportsoziologie. Schorndorf: Hofmann.

A detailed program with additional references will be delivered at the beginning of the lecture.
376-1155-00LThe Musculoskeletal System and Work Information
Does not take place this semester.
W3 credits2Vto be announced
AbstractConsolidated findings of movement sciences concerning deterioration, overload and regeneration of the musculoskeletal system are an important basis for an ergonomic working environment. The following topics are covered: Muscle fatigue during the 8-hour day, use of the computer mouse, backaches, Tendinitis, nerve compression, epidemiology, prevention, rehabiliatation, laws, measuring procedures.
ObjectiveGoal of the course is the activation of physiological and patho-physiological insights for the understanding of loads of the musculoskeletal system during work. Prevention and rehabilitation of work related musculoskeletal disease will be discussed with the help of a bio-psycho-social model. Furthermore, evidence based methods for a healthy work design will be presented.
ContentInsights of human movement sciences concerning wear, overstraining and regeneration of the musculoskeletal system form an important base for an ergonomic work design. The following topics will be covered: Muscle fatigue in an 8-hours-day, mouse appliance, back pain, insertion tendinitis, nerve compression, epidemiology, prevention, rehabilitation, laws, and measurement methods.
Lecture notesSkript und Folien auf NETZ als PDF-Datei zur Verfügung
Prerequisites / NoticeAls Semesterleistung wird von allen eine kleinere, ergonomische Arbeitsplatzbeurteilung erwartet. Zusätzlich wird bis zum 31. Januar eine schriftliche Zusammenfassung oder im Verlauf der Vorlesung ein kurzer Vortrag einer aktuellen Publikation zum Thema verlangt. Alternativ kann eine schriftliche Prüfung am Semesterende abgelegt werden. Bei Wahl von Vortrag oder schriftlichen Zusammenfassung als Semesterleistung wird Vorlesungsbesuch zu mindestens 75% erwartet.
376-1581-00LCancer: Fundamentals, Origin and TherapyW2 credits2GH. Nägeli
AbstractGeneral aspects and etiology of cancer. Epidemiology of cancer. Impact of food, physical activity and infections. Genetic predispositions. Molecular basis of cancer development. Concept of oncogenes and tumor suppressor genes. Cancer stem cells. Interactions between chemicals and DNA. Test systems to recognize mutagenic chemicals. Conventional and new therapeutic strategies.
ObjectiveStudents are able to describe selected chemicals, biological and molecular processes that occur in cells spontaneously or after physical or chemical exposure and resulting in a tumor. They are able to list important cancer-inducing agents and explain the respective mechanism of action. They have knowledge of significant risk factors for cancer diseases. They are confronted with the basics of toxicology and they can explain the principle of the most common therapeutic strategies.
ContentThe lecture deals with problems of tumor epidemiology (causes, mortality, incidence). Cancer is delineated as a multi-step process. Classes of chemical compounds that induce cancer are discussed as well as the reactive metabolites that may be built from. Covalent binding to DNA is discussed and different types of mutations resulting therof. A selection of proto-oncogenes and tumor suppressor genes is presented. Their function will be discussed as well as the changes which are found in these genes in tumor cells, starting from single nucleotide exchanges up to large deletions.
The reason for genetic predisposition to cancer will be discussed as well as cancer relevant aspects of cell cycle regulation. The role of tumor microenvironments and phenomenons like angiogenesis and metastasis are presented as well as the mechanisms that protect the genome from mutagenic damage. Further subjects address old and new strategies of cancer treatment. Personalised cancer treatment.
Lecture notesHandouts with reproductions of all presented transparencies will be distributed.
Literature- Weinberg, Robert: The biology of Cancer. 2014. 876 S.; ISBN 978-0-8153-4220-5, Garland Science, New York, USA

additional informations are given during the lecture
Prerequisites / NoticeThe lecture requires an active participation of the students. All students will participate in individual or group work focussing on specific subject of the lecture. Students will have ample time for preparation during lecture time.
376-1665-00LTraining and Coaching I Restricted registration - show details W3 credits2GO. Buholzer
AbstractThe combining of training and coaching as in the example of sport analysis, which has an effect on youth training and athlete development
Objective-To develop basics for a differentiate analyses of sports (model)
-To develop a profile of requirements for specific sports
-To develop competencies of training with youth and talents
-To develop the basics of talent training in theory and practice
-To observe athletes in case studies, make judgments and conclusion
ContentDas Modell der Sportartenanalyse
Die Relevanz der einzelnen Leistungsfaktoren
Das Modell der Wettkampfanalyse
Folgerungen für das Training und Coaching in der Sportart
Folgerungen für das Nachwuchstraining
Folgerungen für die Athletenauswahl, Athletenbeobachtung und -betreuung
Das Nachwuchs- und Talenttraining (Sichtung, Selektion, Förderung)
Projekte aus der Praxis (Talent- und Nachwuchstraining)
Praxisinput zum Thema Koordination, motorische Grundbedürfnisse, Kraft und Gesundheit
Praxisbeispiele erarbeiten und planen
Konkrete Athletenbeobachtung
Lecture notesDie Skript- (Lektionsunterlagen) werden im Rahmen des Semesters abgeben und auf Homepage veröffentlicht.
LiteratureStruktur sportlicher Leistung (Modellansatz von Gundlach; (Trainingswissenschaften S. 45 - 49; Stiehler(Konzag/Döbler)

Leistungsdiagnostische Verfahren, Stiehler(Konzag/Döbler)

Training fundiert erklärt, Handbuch der Trainingslehre, Ingold Verlag 2006

Optimales Training, J. Weineck, 14. Auflage permid Verlag, 2007

Das sportliche Talent, W. Joch, Meyer&Meyer Verlag, 2002

Das neue Konditionstraining, Grosser/Starischka/Zimmermann, blv 2002
Prerequisites / NoticeKredit/Prüfung
Für die Kreditvergabe sind die vorgeschriebenen Semesterarbeiten und die Präsenz zwingend. Die Benotung erfolgt durch eine schriftliche Arbeit.

Planung
Die Planungsunterlagen werden zu Semesterbeginn abgegebenen, sind provisorisch und können vom Dozenten geändert werden.
Die Praxislektionen werden jeweils am Mittwoch von 13.00 - 15.00 abgehalten. Die Termine werden in Absprache festgelegt.

Die Semesterarbeit ist 4 Wochen nach Semesterende abzugeben.

Die Veranstaltung (Theorie) findet am Do von 16.15 - 18.00 statt, die Praxis findet in der Regel am Mi 12.30 - 14.30 statt. Die Ausschreibung wird 4 Wochen vor Semesterbeginn veröffentlicht.
376-1716-00LBasics of Exercise Therapy Restricted registration - show details
Number of participants limited to 30.

Possible from the 5th semester on. Requirement:"Introduction of Exercise Therapy" passed.
W2 credits2VK. Marschall
AbstractBasics of Exercise Therapy:
A: diagnostic, anamnesis, diagnostic of movement and funktion, assessments in exercise therapy, diagnostic of experience and behavior in relation to movement
B: biological-medical basics, pathophysiological Basics (internal, orthopedic and psychological deseases.

C: didactic knowledge, Reha-didactic
ObjectiveStudents learn the assessments to plan an exercise-therapy-treatment.
They are able to use them. They're able to integrate biological and medical basics.
They are able to preparate a therapy-session
ContentGrundlagen der Diagnostik, Anamnese,
Bewegungsdiagnostik, Funktionsdiagnostik
Sport- und Bewegungstherapeutische Testverfahren
Motorische Basisdiagnostik
Diagnostik bewegungsbezogenen Erlebens und Verhaltens
Biologisch-medizinische Grundlagen
Biomechanik (v.a. Gelenke), Pathophysiologische Grundlagen, Modelle der Methodik und Didaktik, Lektionsplanung
Lecture noteswird vor Semesterbeginn elektronisch zur Verfügung gestellt
Literature- Schüle / Huber: Grundlagen der Sporttherapie, Deutscher Ärzteverlag , Köln 2012
- Deimel et al.: Neue aktive Wege in Prävention und Rehabilitation, Deutscher Ärzteverlag, Köln 2007
Prerequisites / Noticelecture "Introduction in Exercise Therapie" ist prerequisite

90% of the lections students must be present.

open-book-test in the last sessions at 20.12.2017
376-1717-00LApplied Basics in Sports and Exercise Therapy Restricted registration - show details
Number of participants limited to 30.

Possible from the 5th semester on. Requirement:"Introduction of Exercise Therapy" passed.
W2 credits2VB. Spörri Kälin, B. Keller
AbstractCommunication skills and methods of psychoregulation applied to the area of Sports and Exersice Therapy
ObjectiveThe students are able to plan, lead through and evaluate conversations with patients.
The students are familiar with one method of psychoregulation.
The students are able to apply their knowledge from the previous two courses to practical situations of Sports Therapy and Exercise Therapy.
Contentcommunication/conversation with patients
psychoregulation: relaxation
Lecture notesskript will be on e-learning-platform
Prerequisites / NoticeThe two courses "Introduction in Sports and Exersice Therapy" have been completed successfully.
Taking part in the lecture 90% or above.
376-1722-00LSpinal Cord Injury and Exercise
Prerequisite: Anatomy and Physiology
W2 credits2VC. Perret
AbstractIntensive discussion concerning complications of a spinal cord injury and their consequences on trainability and exercise performance of persons sitting in a wheelchair. Overview on the clinical application of exercise testing as well as on the implementation of sport scientific findings to optimise performance of spinal cord injured subjects in rehabilitation and elite sports.
ObjectiveKnowledge of the pathophysiology and the concomitant complications of a spinal cord injury and the consequences for physical exercise and trainability during rehabilitation as well as in recreational and elite sport.
ContentThe following issues will be discussed: Epidemiology and etiology of spinal cord injury; complications and consequences of spinal cord injury; trainability/exercise physiology and spinal cord injury; history and organisation of wheelchair sports; elite sport and spinal cord injury
LiteratureGeneral literature:

G.A. Zäch, H. G. Koch
Paraplegie - ganzheitliche Rehabilitation
Karger-Verlag, 2006
ISBN 3-8055-7980-2

V. Goosey-Tolfrey
Wheelchair sport: A complete guide for athletes, coaches and teachers
Human Kinetics, 2010

Y.C. Vanlandewijck, W.R. Thompson
The Paralympic Athlete
Wiley-Blackwell, 2011
ISBN 978-1-4443-3404-3

Liz Broad
Sports Nutrition for Paralympic Athletes
CRC Press 2014
ISBN 978-1-4665-0756-2

Y.C. Vanlandewijck, W.R. Thompson
Training and Coaching the Paralympic Athlete
Wiley-Blackwell, 2016
ISBN 978-1-119-04433-8
Prerequisites / NoticeVoraussetzung:Vorlesung Anatomie/Physiologie besucht!
529-0731-00LNucleic Acids and CarbohydratesW6 credits3GD. Hilvert, P. A. Kast, S. J. Sturla, H. Wennemers
AbstractStructure, function and chemistry of nucleic acids and carbohydrates. DNA/RNA structure and synthesis; recombinant DNA technology and PCR; DNA arrays and genomics; antisense approach and RNAi; polymerases and transcription factors; catalytic RNA; DNA damage and repair; carbohydrate structure and synthesis; carbohydrate arrays; cell surface engineering; carbohydrate vaccines
ObjectiveStructure, function and chemistry of nucleic acids and carbohydrates. DNA/RNA structure and synthesis; recombinant DNA technology and PCR; DNA arrays and genomics; antisense approach and RNAi; polymerases and transcription factors; catalytic RNA; DNA damage and repair; carbohydrate structure and synthesis; carbohydrate arrays; cell surface engineering; carbohydrate vaccines
ContentStructure, function and chemistry of nucleic acids and carbohydrates. DNA/RNA structure and synthesis; recombinant DNA technology and PCR; DNA arrays and genomics; antisense approach and RNAi; polymerases and transcription factors; catalytic RNA; DNA damage and repair; carbohydrate structure and synthesis; carbohydrate arrays; cell surface engineering; carbohydrate vaccines
Lecture notesNo script; illustrations from the original literature relevant to the individual lectures will be provided weekly (typically as handouts downloadable from the Moodle server).
LiteratureMainly based on original literature, a detailed list will be distributed during the lecture
529-1023-00LPhysical Chemistry I (for Biology and Pharmacy)W3 credits2V + 1UR. Riek, H. P. Lüthi
AbstractThe laws of thermodynamics: empirical temperature, energy, entropy. Models and standard states: ideal gases, ideal solutions and mixtures, activity, standard thermodynamic values. Reaction thermodynamics: chemical potential, thermodynamic parameters of reactions, equilibrium conditions and their temperature and pressure dependence, biochemical reactions, surface effects, colligative properties.
ObjectiveUnderstanding the fundamental thermodynamic properties of chemical and biological systems.
ContentThe laws of thermodynamics: empirical temperature, energy, entropy. Models and standard states: ideal gases, ideal solutions and mixtures, activity, standard thermodynamic values. Reaction thermodynamics: chemical potential, thermodynamic parameters of reactions, equilibrium conditions and their temperature and pressure dependence, biochemical reactions, surface effects, colligative properties.
Lecture notesin process, will be distributed at the beginning of the first lecture
Literature1) Atkins, P.W., 1999, Physical Chemistry, Oxford University Press, 6th ed., 1999.
2) Moore, W.J., 1990: Grundlagen der physikalischen Chemie, W. de Gruyter, Berlin.
3) Adam, G., Läuger, P., Stark, G., 1988: Physikalische Chemie und Biophysik, 2. Aufl., Springer Verlag, Berlin.
Prerequisites / NoticePrerequisite: mathematics I+II, functions of multiple variables, partial derivatives.
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