Search result: Catalogue data in Spring Semester 2019

Health Sciences and Technology Bachelor Information
Bachelor Studies (Programme Regulations 2013)
Second Year Compulsary Subjects
Examination Blocks
Examination Block 3
NumberTitleTypeECTSHoursLecturers
376-0152-00LAnatomy and Physiology II Information O5 credits4VM. Ristow, K. De Bock, M. Kopf, L. Slomianka, C. Spengler
AbstractBasic knowledge of the anatomy and physiology of the gastrointestinal tract, endocrine organs, urinary system and the reproductive system. Knowlewdge of the basic mechanisms of pathobiology. Study of all human tissues and selected organs by examining slides under the light microscope.
ObjectiveFoundations of human anatomy and physiology and basics of clinical pathophysiology
ContentShort overview of human anatomy, physiology and general pathology.
3rd semester:
Principles of histology and embryology. Anatomy and physiology: nervous system, muscle, sensory organs, circulatory system, respiratory system.
4rd semester:
Anatomy and physiology: gastrointestinal tract, endocrine system, metabolism and thermoregulation, integumentary system, blood and immune system, urinary system, circadian rhythm, reproductive system, pregnancy and birth.
LiteratureAnatomie: Martini, Timmons, Tallitsch, "Anatomie", Pearson; oder Schiebler, Korf, "Anatomie", Steinkopff / Springer; oder Spornitz, "Anatomie und Physiologie, Lehrbuch und Atlas für Pflege-und Gesundheitsfachberufe", Springer

Physiologie: Thews/Mutschler/Vaupel: Anatomie, Physiologie, Pathophysiologie des Menschen,
Wissenschaftliche Verlagsgesellschaft, Stuttgart

oder

Schmidt/Lang/Thews: Physiologie des Menschen, Springer-Verlag, Heidelberg
Prerequisites / NoticeDer Besuch der Anatomie und Physiologie I - Vorlesung ist Voraussetzung, da die Anatomie und Physiologie II - Vorlesung auf dem Wissen der im vorangegangenen Semester gelesenen Anatomie und Physiologie I - Vorlesung aufbaut.
376-0153-00LHistology Information O2 credits2GD. P. Wolfer, I. Amrein, L. Slomianka
AbstractPractical at the light microscope based on the lectures "Anatomie" 1+2 with an introduction in histological techniques. In the first part participants study examples of epithelia, connective and supporting tissues, muscle and nervous tissue. The second part is devoted to the microscopic anatomy of selected organs.
ObjectiveBy working with the microscope, participants gain a deeper understating of the lecture topics, in particular in microscopic anatomy. They acquire the ability to examine tissue sections with the microscope, to recognize organ-typical structures and to identify the organ of origin.
LiteratureSuggested reading
Lüllmann-Rauch R, Asan E: Taschenlehrbuch Histologie
Kühnel W: Taschenatlas Histologie
Prerequisites / NoticeBased on:
376-0151-00 "Anatomie und Physiologie" I
376-0150-00 "Anatomie und Physiologie" II
402-0084-00LPhysics II4 credits3V + 1UG. Dissertori
AbstractThis course is an introduction to classical physics, with special focus on applications in medicine.
ObjectiveObtain an understanding of basic concepts in classical physics and their application (using mathematical pre-knowledge) to the solution of simple problems, including certain applications in medicine.

Obtain an understanding of relevant quantities and of orders of magnitude.
ContentElectromagnetism;
Thermodynamics;
Optics.
Lecture notesWill be distributed at the start of the semester.
Literature"Physik für Mediziner, Biologen, Pharmazeuten", von Alfred Trautwein, Uwe Kreibig, Jürgen Hüttermann; De Gruyter Verlag.
Prerequisites / NoticeVoraussetzung Mathematik I+II (Studiengänge Gesundheitswissenschaften und Technologie bzw. Humanmedizin) / Mathematik-Lehrveranstaltungen des Basisjahres (Studiengänge Chemie, Chemieingenieurwissenschaften bzw. Interdisziplinäre Naturwissenschaften)
Examination Block 4
NumberTitleTypeECTSHoursLecturers
376-0008-00LAdvanced Anatomy and Physiology II: Advanced Physiology and Pathophysiology Restricted registration - show details
Only for Health Sciences and Technology BSc.
O4 credits4VK. De Bock, O. Bar-Nur, M. Detmar, G. A. Kuhn, M. Ristow, G. Schratt, C. Spengler, C. Wolfrum, M. Zenobi-Wong
AbstractIn-depth theory to molecular and pathophysiological aspects of nerves, muscles, heart , circulatory , respiratory and sensory organs .
ObjectiveIn-depth knowledge of anatomy and physiology.
ContentMolecular fundamentals of physiological processes, processes of disease development.
376-0206-00LBiomechanics IIO4 credits3GB. Taylor, P. Schütz, F. Vogl
AbstractIntroduction in dynamics, kinetics and kinematic of rigid and elastic multi-body systems with examples in biology, medicine and especially the human movement
ObjectiveThe students are able
- to analyse and describe dynamic systems
- to explain the mechanical laws and use them in biology and medicine
ContentThe human movement from a mechanical point of view. Kinetic and kinematic concepts and their mechanical description. Energy and momentum of a movement. Mechanical description of a multi-body system.
376-1611-00LBiomedical Interfaces Information O4 credits2V + 1UJ. Möller, R. Konradi, V. Vogel
AbstractThis class serves as an introduction into the design of materials for biomedical applications. Its focus lies on controlling interactions at the interface between biomolecules or living cells and synthetic materials. Knowing some basic concepts allows us to define prototypical requirements for material surfaces and to utilize molecular engineering principles for their realization.
Objective1. The students will know basic rules that determine the interaction of biological molecules or cells with synthetic materials on the nanoscale.
2. The students will be able to define essential requirements how to functionalize materials in the context of specific biomedical applications.
3. The students will be able to predict the outcome of self-assembly processes and utilize these to achieve a desired function or biological behavior at interfaces.
Content- protein-surface interactions
- anti-adhesive surface coatings
- biosensors
- bacteria-surface interactions
- cell-nanoparticle interactions
- drug delivery systems
- cell-matrix interactions
- soft tissue engineering
Lecture notesHandouts of the lecture can be accessed online.
LiteratureSelected chapters of
- Biomaterials Science: an Introduction to Materials in Medicine, by B. Ratner, 3rd Ed. Academic Press (2013).
- Biomimetic Materials and Design: Biointerfacial Strategies, Tissue Engineering and Targeted Drug Delivery, by A.K. Dillow and A.M. Lowman, CRC Press (2002).
- Biomaterials: Principles and Practices, by J.Y. Wong et al., CRC Press (2013).
- Molecular Biology of the Cell, by B. Alberts et al., Taylor & Francis, 5th Ed. (2007).
Detailed literature references will be provided in the lectures.
Prerequisites / NoticeThis interdisciplinary class addresses students from all disciplines at the Bachelor level. We premise a profound basic knowledge of cell biology and biochemistry.
Third Year Focus Courses
Focus Courses: Human Movement Science and Sport
NumberTitleTypeECTSHoursLecturers
376-0204-00LExercise SciencesW4 credits3GE. de Bruin, P. Eggenberger, A. Krebs
AbstractEvidence-based findings on the training of endurance, strength, and speed, planning and periodization of training, as well as motor learning will be presented and discussed in relation to specific age groups (childhood to older age), and performance levels. The theoretical knowledge will be applied in an annual training plan for an individually chosen sport/performance level.
ObjectiveUnderstand and critically evaluate evidence-based training recommendations for specific groups (children/youth, adults, older adults, recreational/high performance sport) and apply and evaluate this knowledge within a goal-oriented training plan.
ContentLecture:
- Evidence-based research in exercise sciences
- Endurance, strength, and speed training
- Training in childhood and youth
- Training in older age
- Analysis of a specific sport, planning and periodization models
- Motor learning in sports practice

Training sessions:
- Development of a goal-oriented annual training plan for an individually chosen sport/performance level, based on evidence from the exercise sciences.

Practice in the gym:
- Practical examples for the training of strength and speed
- Motor learning experiments
Lecture notesLecture slides and papers on the Moodle platform.
LiteratureG.G. Haff & N.T. Triplett (eds): Essentials of Strength Training and Conditioning. Human Kinetics, 4th edition, 2016.

W.E. Amonette, K.L. English, W.J. Kraemer: Evidence-Based Practice in Exercise Science. The Six-Step Approach. Human Kinetics, 2016.
376-0202-00LNeural Control of Movement and Motor LearningW4 credits3GN. Wenderoth
AbstractThis course extends the students' knowledge regarding the neural control of movement and motor learning. Particular emphasis will be put on those methods and experimental findings that have shaped current knowledge of this area.
ObjectiveKnowledge of the physiological and anatomic basis underlying the neural control of movement and motor learning. One central element is that students have first hands-on experience in the lab where small experiments are independently executed, analysed and interpreted.
Focus Courses: Molecular Health Sciences
NumberTitleTypeECTSHoursLecturers
551-0318-00LImmunology IIW3 credits2VA. Oxenius, M. Kopf, S. R. Leibundgut, E. Wetter Slack, further lecturers
AbstractIntroduction into the cellular and molecular basis of the immune system and immune responses against diverse pathogens, tumors, transplants, and self (autoimmunity)
ObjectiveThe lectures will provide a detailed understanding:
- how innate and adaptive immune responses interact at the cellular and molecular level.
- how the immune system recognizes and fights against pathogenic microorganisms including viruses, bacteria, and parasites.
- why lymphocytes tolerate self molecules.
- about function and dysfunction the intestinal immune system.
- immunopathology and inflammatory diseases.
ContentThe aim of lecture is to understand:
> How pathogens are recognized by the innate immune system
> Immune defense against various pathogens
> Immunology of the skin, lung and intestines
> Tumor immunology
> Migration and homing of immune cells
> tolerance and autoimmunity
> T cell memory
Lecture notesPresentations of the lecturers are available at the Moodle link
LiteratureRecommended: Kuby Immunology (Freeman)
551-0326-00LCell Biology Information W6 credits4VS. Werner, M. Bordoli, R. Henneberger, W. Kovacs, M. Schäfer, U. Suter, A. Wutz
AbstractThis Course introduces principle concepts, techniques, and experimental strategies used in modern Cell Biology. Major topics include: neuron-glia interactions in health and disease; mitochondrial dynamics; stem cell biology; growth factor action in development, tissue repair and disease; cell metabolism, in particular sensing and signaling mechanisms, cell organelles, and lipid metabolism.
Objective-To prepare the students for successful and efficient lab work by learning how to ask the right questions and to use the appropriate techniques in a research project.
-To convey knowledge about neuron-glia interactions in health and disease.
- To provide information on different types of stem cells and their function in health and disease
-To provide information on growth factor signaling in development, repair and disease and on the use of growth factors or their receptors as drug targets for major human diseases
-To convey knowledge on the mechanisms underlying repair of injured tissues
-To provide the students with an overview of mitochondrial dynamics.
-Providing an understanding of RNA processing reactions and their regulations.
-To provide a comprehensive understanding of metabolic sensing mechanisms occurring in different cell types and organelles in response to glucose, hormones, oxygen, nutrients as well as lipids, and to discuss downstream signaling pathways and cellular responses.
-To provide models explaining how disturbances in complex metabolic control networks and bioenergetics can lead to disease and to highlight latest experimental approaches to uncover the intricacies of metabolic control at the cellular and organismal level.
-Providing the background and context that foster cross-disciplinary scientific thinking.
376-0209-00LMolecular Disease MechanismsW6 credits4VC. Wolfrum, H. Gahlon, M. Kopf
AbstractIn this course the mechanisms of disease development will be studied. Main topics will be:

1. Influence of environmental factors with an emphasis on inflammation and the immune response.
2. Mechanisms underlying disease progression in metabolic disorders, integrating genetic and environmental factors.
3. Mechanisms underlying disease progression in cancer, integrating genetic and environment
ObjectiveTo understand the mechanisms governing disease development with a special emphasis on genetic and environmental associated components
Lecture notesAll information can be found at:

https://moodle-app2.let.ethz.ch/course/view.php?id=690

The enrollment key will be provided by email
Focus Courses: Medical Technology
NumberTitleTypeECTSHoursLecturers
376-0210-00LBiomechatronics
Primarily designed for HSTstudents

The Biomechatronics lecture is not appropriate for students who already attended the lecture "Physical Human-Robot Interaction"(376-1504-00L), because it covers similar topics.

Matlab skills are beneficial-> online Tutorial http://www.imrtweb.ethz.ch/matlab/
W4 credits3GR. Riener, R. Gassert
AbstractDevelopment of mechatronic systems (i.e. mechanics, electronics, computer science and system integration) with inspiration from biology and application in the living (human) organism.
ObjectiveThe objective of this course is to give an introduction to the fundamentals of biomechatronics, through lectures on the underlying theoretical/mechatronics aspects and application fields. In the exercises, these concepts will be intensified and trained on the basis of specific examples. The course will guide students through the design and evaluation process of such systems, and highlight a number of applications.

By the end of this course, you should understand the critical elements of biomechatronics and their interaction with biological systems, both in terms of engineering metrics and human factors. You will be able to apply the learned methods and principles to the design, improvement and evaluation of safe and efficient biomechatronics systems.
ContentThe course will cover the interdisciplinary elements of biomechatronics, ranging from human factors to sensor and actuator technologies, real-time signal processing, system kinematics and dynamics, modeling and simulation, controls and graphical rendering as well as safety/ethical aspects, and provide an overview of the diverse applications of biomechatronics technology.
Lecture notesSlides will be distributed through moodle before the lectures.
LiteratureBrooker, G. (2012). Introduction to Biomechatronics. SciTech Publishing.
Riener, R., Harders, M. (2012) Virtual Reality in Medicine. Springer, London.
Prerequisites / NoticeNone
376-0022-00LImaging and Computing in Medicine Restricted registration - show details W4 credits3GR. Müller, P. Christen
AbstractImaging and computing methods are key to advances and innovation in medicine. This course introduces established fundamental as well as modern techniques and methods of imaging and computing in medicine.
Objective1. Understanding and practical implementation of biosignal processes methods for imaging
2. Understanding of imaging techniques including radiation imaging, radiographic imaging systems, computed tomography imaging, diagnostic ultrasound imaging, and magnetic resonance imaging
3. Knowledge of computing, programming, modelling and simulation fundamentals
4. Computational and systems thinking as well as scripting and programming skills
5. Understanding and practical implementation of emerging computational methods and their application in medicine including artificial intelligence, deep learning, big data, and complexity
6. Understanding of the emerging concept of personalised and in silico medicine
7. Encouragement of critical thinking and creating an environment for independent and self-directed studying
ContentImaging and computing methods are key to advances and innovation in medicine. This course introduces established fundamental as well as modern techniques and methods of imaging and computing in medicine. In imaging, biosignal processing, radiation imaging, radiographic imaging systems, computed tomography imaging, diagnostic ultrasound imaging, and magnetic resonance imaging are covered. In computing, computing, programming, and modelling and simulation fundamentals are covered as well as their application in artificial intelligence and deep learning, complexity and systems medicine, big data and personalised medicine, and computational physiology and in silico medicine.
The course is structured as a seminar in three parts of 45 minutes with video lectures and a flipped class room setup: in the first part (TORQUEs: Tiny, Open-with-Restrictions courses focused on QUality and Effectiveness), students study the basic concepts in short video lectures on the online learning platform Moodle. At the end of this first part, must post a number of questions in the Moodle forum that will be addressed in the second part of the lectures using a flipped classroom concept. First, the lecturers may prepare additional teaching material to answer the posted questions and potentially discuss further questions (Q&A). Second, the students will form small groups to acquire additional knowledge online or from additionally distributed material and to present their findings to the rest of the class.
Lecture notesStored on Moodle.
Focus Courses: Neurosciences
NumberTitleTypeECTSHoursLecturers
376-1306-00LClinical Neuroscience Information W3 credits3GG. Schratt, University lecturers
AbstractThe lecture series "Clinical Neuroscience" presents a comprehensive, condensed overview of the most important neurological diseases, their clinical presentation, diagnosis, therapy options and possible causes. Patient demonstrations (Übungen) follow every lecture that is dedicated to a particular disease.
ObjectiveBy the end of this module students should be able to:
- demonstrate their understanding and deep knowledge concerning the main neurological diseases
- identify and explain the different clinical presentation of these diseases, the methodology of diagnosis and the current therapies available
- summarize and critically review scientific literature efficiently and effectively
376-0202-00LNeural Control of Movement and Motor LearningW4 credits3GN. Wenderoth
AbstractThis course extends the students' knowledge regarding the neural control of movement and motor learning. Particular emphasis will be put on those methods and experimental findings that have shaped current knowledge of this area.
ObjectiveKnowledge of the physiological and anatomic basis underlying the neural control of movement and motor learning. One central element is that students have first hands-on experience in the lab where small experiments are independently executed, analysed and interpreted.
551-0326-00LCell Biology Information W6 credits4VS. Werner, M. Bordoli, R. Henneberger, W. Kovacs, M. Schäfer, U. Suter, A. Wutz
AbstractThis Course introduces principle concepts, techniques, and experimental strategies used in modern Cell Biology. Major topics include: neuron-glia interactions in health and disease; mitochondrial dynamics; stem cell biology; growth factor action in development, tissue repair and disease; cell metabolism, in particular sensing and signaling mechanisms, cell organelles, and lipid metabolism.
Objective-To prepare the students for successful and efficient lab work by learning how to ask the right questions and to use the appropriate techniques in a research project.
-To convey knowledge about neuron-glia interactions in health and disease.
- To provide information on different types of stem cells and their function in health and disease
-To provide information on growth factor signaling in development, repair and disease and on the use of growth factors or their receptors as drug targets for major human diseases
-To convey knowledge on the mechanisms underlying repair of injured tissues
-To provide the students with an overview of mitochondrial dynamics.
-Providing an understanding of RNA processing reactions and their regulations.
-To provide a comprehensive understanding of metabolic sensing mechanisms occurring in different cell types and organelles in response to glucose, hormones, oxygen, nutrients as well as lipids, and to discuss downstream signaling pathways and cellular responses.
-To provide models explaining how disturbances in complex metabolic control networks and bioenergetics can lead to disease and to highlight latest experimental approaches to uncover the intricacies of metabolic control at the cellular and organismal level.
-Providing the background and context that foster cross-disciplinary scientific thinking.
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