Search result: Catalogue data in Spring Semester 2019

Health Sciences and Technology Master Information
Major in Human Movement Science and Sport
Compulsory Courses
376-0302-00LPracticing Translational Science Restricted registration - show details
Only for Health Sciences and Technology MSc.
O2 credits4AJ. Goldhahn, S. Ben-Menahem, C. Ewald, W. Karlen
AbstractTranslational Science is a cross disciplinary scientific research that is motivated by the need for practical applications that help patients. The students should apply knowledge they gained in the prior course during a team approach focused on one topic provided by the supervisor. Each student has to take a role in the team and label clear responsibility and contribution.
ObjectiveAfter completing this course, students will be able to apply:
a) Principles of translational science (including project planning, ethics application, basics of resource management and interdisciplinary communication)
b) The use of a translational approach in project planning and management
Prerequisites / NoticePrerequisite: lecture 376-0300-00 "Translational Science for Health and Medicine" passed.
Electives Courses I
376-0224-00LClinical Exercise PhysiologyW3 credits2VC. Spengler, C. Schmied, further lecturers
AbstractThis lecture series provides a comprehensive overview of the most important aspects of clinical exercise testing for diagnosis and assessment of functional status in different patient populations, e.g. patients with pulmonary, cardiac or neuro-muscular disease, with obesity, young or old age. Also, special aspects in the context of training perscriptions in these populations will be discussed.
ObjectiveBy the end of this module, students:
- Have the theoretical basis for disease-specific exercise testing and interpretation in clinical settings
- Know important aspects for disease-specific exercise-training prescriptions and assessment of training progress
- Are able to critically review and interpret scientific literature in the context of physical fitness, performance and training in different patient populations
Lecture notesHandouts are provided via moodle.
LiteratureHandouts are provided via moodle.
Prerequisites / NoticeThe courses "Anatomie & Physiologie I+II", as well as "Sportphysiologie" (or Anatomy, Physiology and Exercise Physiology - equivalents for students without HST-BSc), are required.
376-1168-00LSports Biomechanics Restricted registration - show details W3 credits2VS. Lorenzetti
AbstractVarious types of sport are studied from a mechanical point of view. Of particular interest are the key parameters of a sport as well as the performance relevant indicators.
ObjectiveThe aim of this lecture is to enable the students to study a sport from a biomechanical viewpoint and to develop significant models for which evaluations of the limitations and verifications can be carried out.
ContentSport biomechanics is concerned with the physical and mechanical basic principles of sports. The lecture requires an in-depth mechanical understanding on the side of the student. In this respect, the pre-attendance of the lectures Biomechanics II and Movement and Sports Biomechanics or an equivalent course is expected. The human body is treated as a mechanical system during sport. The interaction of the active and passive movements and outside influences is analysed. Using sports such as ski-jumping, cycling, or weight training, applicable models are created, analyzed and suitable measuring methods are introduced. In particular, the constraints as well as the limitations of the models are of great relevance. The students develop their own models for different sport types, critically discuss the advantages and disadvantages and evaluate applicable measurement methods.
Lecture notesHandout will be distributed.
376-1306-00LClinical Neuroscience Information W3 credits3GG. Schratt, University lecturers
AbstractThe lecture series "Clinical Neuroscience" presents a comprehensive, condensed overview of the most important neurological diseases, their clinical presentation, diagnosis, therapy options and possible causes. Patient demonstrations (Übungen) follow every lecture that is dedicated to a particular disease.
ObjectiveBy the end of this module students should be able to:
- demonstrate their understanding and deep knowledge concerning the main neurological diseases
- identify and explain the different clinical presentation of these diseases, the methodology of diagnosis and the current therapies available
- summarize and critically review scientific literature efficiently and effectively
376-1660-00LScientific Writing, Reporting and Communication Restricted registration - show details
Number of participants limited to 30.

Only for Health Sciences and Technology MSc
W3 credits2VB. Taylor
AbstractThis course aims to teach many of the unwritten rules on how to communicate effectively, from writing reports or manuscripts (or indeed their Master thesis!) through to improving skills in oral presentations, and presenting themselves at interview.
ObjectiveThis course will teach students to communicate effectively in official environments, including:
- writing manuscripts, theses, CVs, reports etc
- presenting posters
- oral presentations
- critical reviews of literature
376-1719-00LStatistics for Experimental ResearchW3 credits2VR.  van de Langenberg
AbstractStudents will learn the necessary statistical concepts and skills to independently (1) design experiments (2) analyse experimental data and (3) report analyses and results in a scientifically appropriate manner.
ObjectiveAfter successful completion of the course, students should be able to:
1. Determine appropriate experimental designs and choose, justify and perform the appropriate statistical analyses using R.
2. Report analyses and results in a scientifically appropriate manner, as laid out by the Publication Manual of the American Psychological Association (APA, sixth edition).
ContentWe will cover basic statistical concepts (e.g., central tendency, variability, data distribution), the t-test (dependent and independent), ANOVA (univariate, factorial and repeated measures), correlation, multiple regression, nonparametric techniques, validity and reliability tests, effect size, data transformation, power and sample size estimation.
Lecture notesLecture notes will be delivered in the form of commented presentations in Microsoft Powerpoint (i.e. pptx) format. R practical session assignments will be delivered in pdf-format.
LiteratureBoth in the lectures and in the tutorials and practical sessions, we will refer students to the following publication:

Field A, Miles J, Field Z (2013) Discovering Statistics Using R. Sage Publications Ltd, London, UK
Elective Courses II
227-0384-00LUltrasound Fundamentals, Imaging, and Medical Applications Restricted registration - show details
Number of participants limited to 60.
W4 credits3GO. Göksel
AbstractUltrasound is the only imaging modality that is nonionizing (safe), real-time, cost-effective, and portable, with many medical uses in diagnosis, intervention guidance, surgical navigation, and as a therapeutic option. In this course, we introduce conventional and prospective applications of ultrasound, starting with the fundamentals of ultrasound physics and imaging.
ObjectiveStudents can use the fundamentals of ultrasound, to analyze and evaluate ultrasound imaging techniques and applications, in particular in the field of medicine, as well as to design and implement basic applications.
ContentUltrasound is used in wide range of products, from car parking sensors, to assessing fault lines in tram wheels. Medical imaging is the eye of the doctor into body; and ultrasound is the only imaging modality that is nonionizing (safe), real-time, cheap, and portable. Some of its medical uses include diagnosing breast and prostate cancer, guiding needle insertions/biopsies, screening for fetal anomalies, and monitoring cardiac arrhythmias. Ultrasound physically interacts with the tissue, and thus can also be used therapeutically, e.g., to deliver heat to treat tumors, break kidney stones, and targeted drug delivery. Recent years have seen several novel ultrasound techniques and applications – with many more waiting in the horizon to be discovered.

This course covers ultrasonic equipment, physics of wave propagation, numerical methods for its simulation, image generation, beamforming (basic delay-and-sum and advanced methods), transducers (phased-, linear-, convex-arrays), near- and far-field effect, imaging modes (e.g., A-, M-, B-mode), Doppler and harmonic imaging, ultrasound signal processing techniques (e.g., filtering, time-gain-compensation, displacement tracking), image analysis techniques (deconvolution, real-time processing, tracking, segmentation, computer-assisted interventions), acoustic-radiation force, plane-wave imaging, contrast agents, micro-bubbles, elastography, biomechanical characterization, high-intensity focused ultrasound and therapy, lithotripsy, histotripsy, photo-acoustics phenomenon and opto-acoustic imaging, as well as sample non-medical applications such as the basics of non-destructive testing (NDT).

Hands-on exercises: These will help to apply the concepts learned in the course, using simulation environments (such as Matlab k-Wave and FieldII toolboxes). The exercises will involve a mix of design, implementation, and evaluation examples commonly encountered in practical applications.

Project: These will be part of the assessment in grading. Projects will be carried out throughout the course, individually or in small groups. Project reporting and presentations will be due at the end of the semester. Topics highly relevant in the field of ultrasound are offered as suggested projects. Students are also welcome to propose custom project topics of their own.
Prerequisites / NoticePrerequisites: Familiarity with basic numerical methods.
Basic programming skills in Matlab.
327-2125-00LMicroscopy Training SEM I - Introduction to SEM Restricted registration - show details
Limited number of participants.

Master students will have priority over PhD students. PhD students may still enroll, but will be asked for a fee (
W2 credits3PK. Kunze, A. G. Bittermann, S. Gerstl, L. Grafulha Morales, J. Reuteler
AbstractThe introductory course on Scanning Electron Microscopy (SEM) emphasizes hands-on learning. Using 2 SEM instruments, students have the opportunity to study their own samples, or standard test samples, as well as solving exercises provided by ScopeM scientists.
Objective- Set-up, align and operate a SEM successfully and safely.
- Accomplish imaging tasks successfully and optimize microscope performances.
- Master the operation of a low-vacuum and field-emission SEM and EDX instrument.
- Perform sample preparation with corresponding techniques and equipment for imaging and analysis
- Acquire techniques in obtaining secondary electron and backscatter electron micrographs
- Perform EDX qualitative and semi-quantitative analysis
ContentDuring the course, students learn through lectures, demonstrations, and hands-on sessions how to setup and operate SEM instruments, including low-vacuum and low-voltage applications.
This course gives basic skills for students new to SEM. At the end of the course, students with no prior experience are able to align a SEM, to obtain secondary electron (SE) and backscatter electron (BSE) micrographs and to perform energy dispersive X-ray spectroscopy (EDX) qualitative and semi-quantitative analysis. The procedures to better utilize SEM to solve practical problems and to optimize SEM analysis for a wide range of materials will be emphasized.

- Discussion of students' sample/interest
- Introduction and discussion on Electron Microscopy and instrumentation
- Lectures on electron sources, electron lenses and probe formation
- Lectures on beam/specimen interaction, image formation, image contrast and imaging modes.
- Lectures on sample preparation techniques for EM
- Brief description and demonstration of the SEM microscope
- Practice on beam/specimen interaction, image formation, image contrast (and image processing)
- Student participation on sample preparation techniques
- Scanning Electron Microscopy lab exercises: setup and operate the instrument under various imaging modalities
- Lecture and demonstrations on X-ray micro-analysis (theory and detection), qualitative and semi-quantitative EDX and point analysis, linescans and spectral mapping
- Practice on real-world samples and report results
Literature- Detailed course manual
- Williams, Carter: Transmission Electron Microscopy, Plenum Press, 1996
- Hawkes, Valdre: Biophysical Electron Microscopy, Academic Press, 1990
- Egerton: Physical Principles of Electron Microscopy: an introduction to TEM, SEM and AEM, Springer Verlag, 2007
Prerequisites / NoticeNo mandatory prerequisites. Please consider the prior attendance to EM Basic lectures (551- 1618-00V; 227-0390-00L; 327-0703-00L) as suggested prerequisite.
327-2126-00LMicroscopy Training TEM I - Introduction to TEM Restricted registration - show details
Number of participants limited to 6. Master students will have priority over PhD students. PhD students may still enroll, but will be asked for a fee (

TEM 1 registration form: Link
W2 credits3PM. Willinger, E. J. Barthazy Meier, A. G. Bittermann, F. Gramm
AbstractThe introductory course on Transmission Electron Microscopy (TEM) provides theoretical and hands-on learning for new operators, utilizing lectures, demonstrations, and hands-on sessions.
Objective- Overview of TEM theory, instrumentation, operation and applications.
- Alignment and operation of a TEM, as well as acquisition and interpretation of images, diffraction patterns, accomplishing basic tasks successfully.
- Knowledge of electron imaging modes (including Scanning Transmission Electron Microscopy), magnification calibration, and image acquisition using CCD cameras.
- To set up the TEM to acquire diffraction patterns, perform camera length calibration, as well as measure and interpret diffraction patterns.
- Overview of techniques for specimen preparation.
ContentUsing two Transmission Electron Microscopes the students learn how to align a TEM, select parameters for acquisition of images in bright field (BF) and dark field (DF), perform scanning transmission electron microscopy (STEM) imaging, phase contrast imaging, and acquire electron diffraction patterns. The participants will also learn basic and advanced use of digital cameras and digital imaging methods.

- Introduction and discussion on Electron Microscopy and instrumentation.
- Lectures on electron sources, electron lenses and probe formation.
- Lectures on beam/specimen interaction, image formation, image contrast and imaging modes.
- Lectures on sample preparation techniques for EM.
- Brief description and demonstration of the TEM microscope.
- Practice on beam/specimen interaction, image formation, Image contrast (and image processing).
- Demonstration of Transmission Electron Microscopes and imaging modes (Phase contrast, BF, DF, STEM).
- Student participation on sample preparation techniques.
- Transmission Electron Microscopy lab exercises: setup and operate the instrument under various imaging modalities.
- TEM alignment, calibration, correction to improve image contrast and quality.
- Electron diffraction.
- Practice on real-world samples and report results.
Literature- Detailed course manual
- Williams, Carter: Transmission Electron Microscopy, Plenum Press, 1996
- Hawkes, Valdre: Biophysical Electron Microscopy, Academic Press, 1990
- Egerton: Physical Principles of Electron Microscopy: an introduction to TEM, SEM and AEM, Springer Verlag, 2007
Prerequisites / NoticeNo mandatory prerequisites. Please consider the prior attendance to EM Basic lectures (551- 1618-00V; 227-0390-00L; 327-0703-00L) as suggested prerequisite.
363-1066-00LDesigning Effective Projects for Promoting Health@Work Restricted registration - show details
Number of participants limited to 30.
W3 credits2GG. Bauer, R. Brauchli, G. J. Jenny
AbstractThe fast changing, flexible and performance-oriented economy implies increasing challenges and opportunities for the health of employees. Creating good working conditions and promoting healthy lifestyles of employees becomes more and more important for employers and employees. Students learn how to develop an effective, real-life project of their choice to promote health@work.
ObjectiveStudents become familiar with challenges and opportunities of a changing world of work. They get an overview of intervention approaches and principles in the fields of worksite health promotion as well as work and organizational psychology. On this basis, they learn how to develop an effective, real life worksite health promotion project of their choice – addressing lifestyle factors or working conditions.
During the project work, they learn to follow the typical phases of selecting/framing a relevant work-related health issue, conducting an analysis, formulating smart objectives, developing a realistic action plan, estimating the time and money needed for these actions, and finally evaluating the impact of the project. This will strengthen their general project management skills.
Students will know how to apply key quality criteria of health promotion projects: 1.) how to follow a systematic, evidence-based approach (project management), 2.) how to assure involvement of and thus acceptance by the users (participation), 3.) how to consider both individual, lifestyle-related and organizational, work-related factors (comprehensiveness), and 4.) how to integrate the project into the routine of the organization to assure sustainability (integration). This will increase the impact of future health promotion projects developed by the students.
D-MTEC students will be able to systematically address employee health and performance in their future management practice. D-HEST students will be able to apply their health promotion knowledge to the challenging context of corporations. D-USYS students will be able to consider lifestyle factors and the working environment in their future work. The exchange among these interdisciplinary student groups will foster their ability to solve real life problems in a transdisciplinary manner. Finally, students get acquainted how to design their future work in a health promoting way.
Content1. Challenges in health@work and intervention approaches
2. Lifestyle interventions at work incl. digital tools
3. Personal and organizational strategies for promoting healthy work
4. Core concepts, values and principles in promoting health@work;
introduction to project work & 7-pillar planning model
5. Framing and analysis of health@work issues
6. Participatory priority setting in health@work projects and defining outcome objectives
7. Combining levels of interventions and defining process objectives
8. Project management
9. Evaluation of process and outcomes
10. Preparation* & presentation of posters of group work

Each lecture combines an input by an expert in the respective field and group discussions. During 8 sessions students will directly apply the acquired knowledge to an own, individual project on a self-chosen topic on health@work. Tutors closely support the students in designing their projects. During the last two dates, the students present their projects to the entire class in a poster format. This presentation will be commented by the course leader and serves as the final course assessment.
Prerequisites / NoticeA course for students dedicated to applied learning through projects. As the whole course is designed as a hands-on workshop for the students, active participation in all lectures is expected. Class size limited to 30 students.
376-0131-00LLaboratory Course in Movement Biomechanics Restricted registration - show details
Only for Health Sciences and Technology MSc.
W3 credits4PR. List, B. Postolka
AbstractSelected experiments in Biomechanics. The practical course includes basic experiments to learn measurement methods and practical applications in Biomechanics.
ObjectiveStudents can gain their first experience in the practical application of measurement methods in Biomechanics by means of basic experimentation. They also learn how to keep records in the laboratory journal.
ContentVarious experiments are offered in the field of Biomechanics.
Lecture notesTexts and further handouts will be provided.
376-0202-00LNeural Control of Movement and Motor LearningW4 credits3GN. Wenderoth
AbstractThis course extends the students' knowledge regarding the neural control of movement and motor learning. Particular emphasis will be put on those methods and experimental findings that have shaped current knowledge of this area.
ObjectiveKnowledge of the physiological and anatomic basis underlying the neural control of movement and motor learning. One central element is that students have first hands-on experience in the lab where small experiments are independently executed, analysed and interpreted.
376-0204-00LExercise SciencesW4 credits3GE. de Bruin, P. Eggenberger, A. Krebs
AbstractEvidence-based findings on the training of endurance, strength, and speed, planning and periodization of training, as well as motor learning will be presented and discussed in relation to specific age groups (childhood to older age), and performance levels. The theoretical knowledge will be applied in an annual training plan for an individually chosen sport/performance level.
ObjectiveUnderstand and critically evaluate evidence-based training recommendations for specific groups (children/youth, adults, older adults, recreational/high performance sport) and apply and evaluate this knowledge within a goal-oriented training plan.
- Evidence-based research in exercise sciences
- Endurance, strength, and speed training
- Training in childhood and youth
- Training in older age
- Analysis of a specific sport, planning and periodization models
- Motor learning in sports practice

Training sessions:
- Development of a goal-oriented annual training plan for an individually chosen sport/performance level, based on evidence from the exercise sciences.

Practice in the gym:
- Practical examples for the training of strength and speed
- Motor learning experiments
Lecture notesLecture slides and papers on the Moodle platform.
LiteratureG.G. Haff & N.T. Triplett (eds): Essentials of Strength Training and Conditioning. Human Kinetics, 4th edition, 2016.

W.E. Amonette, K.L. English, W.J. Kraemer: Evidence-Based Practice in Exercise Science. The Six-Step Approach. Human Kinetics, 2016.
376-0206-00LBiomechanics IIW4 credits3GB. Taylor, P. Schütz, F. Vogl
AbstractIntroduction in dynamics, kinetics and kinematic of rigid and elastic multi-body systems with examples in biology, medicine and especially the human movement
ObjectiveThe students are able
- to analyse and describe dynamic systems
- to explain the mechanical laws and use them in biology and medicine
ContentThe human movement from a mechanical point of view. Kinetic and kinematic concepts and their mechanical description. Energy and momentum of a movement. Mechanical description of a multi-body system.
376-0905-00LFunctional Anatomy Information W3 credits2VD. P. Wolfer, I. Amrein
AbstractIntroduction to the anatomy of the musculoskeletal with the goal to better understand movements and the mechanisms of injuries.
Objective- understanding the three-dimensional organization of the human musculoskeletal system
- correct use of anatomical nomenclature in the description of structure and function
- understanding the connections between morphology and normal function of the musculoskeletal system
- knowledge of selected mechanisms of injury in terms of the underlying anatomy
Content- Allgemeine Anatomie des Bewegungsapparates (Bindegewebe, Knochen, Gelenke, Muskeln)
- Becken und freie untere Extremität (Skelett, Gelenke, Muskeln)
- Wirbelsäule, Brustkorb, Bauchwand (Skelett, Gelenke, Muskeln)
- Schulter und freie obere Extremität (Skelett, Gelenke, Muskeln)
Literature- Gehrke T, Sportanatomie, Rowohlt Taschenbuch Verlag
- Weineck J, Sportanatomie, Spitta-Verlag
- Appel H-J, Stang-Voss C, Funktionelle Anatomie, Springer-Verlag
376-1150-00LClinical Challenges in Musculoskeletal Disorders Restricted registration - show details W2 credits2GM. Leunig, S. J. Ferguson, A. Müller
AbstractThis course reviews musculoskeletal disorders focusing on the clinical presentation, current treatment approaches and future challenges and opportunities to overcome failures.
ObjectiveAppreciation of the surgical and technical challenges, and future perspectives offered through advances in surgical technique, new biomaterials and advanced medical device construction methods.
ContentFoot deformities, knee injuries, knee OA, hip disorders in the child and adolescent, hip OA, spine deformities, degenerative spine disease, shoulder in-stability, hand, rheumatoid diseases, neuromuscular diseases, sport injuries and prevention
376-1178-00LHuman Factors IIW3 credits2VM. Menozzi Jäckli, R. Huang, M. Siegrist
AbstractStrategies, abilities and needs of human at work as well as properties of products and systems are factors controlling quality and performance in everyday interactions. In Human Factors II (HF II), cognitive aspects are in focus therefore complementing the more physical oriented approach in HF I. A basic scientific approach is adopted and relevant links to practice are illustrated.
ObjectiveThe goal of the lecture is to empower students in designing products and systems enabling an efficient and qualitatively high standing interaction between human and the environment, considering costs, benefits, health, well-being, and safety as well. The goal is achieved in addressing a broad variety of topics and embedding the discussion in macroscopic factors such as the behavior of consumers and objectives of economy.
ContentCognitive factors in perception, information processing and action. Experimental techniques in assessing human performance and well-being, human factors and ergonomics in development of products and complex systems, innovation, decision taking, consumer behavior.
LiteratureSalvendy G. (ed), Handbook of Human Factors, Wiley & Sons, 2012
376-1217-00LRehabilitation Engineering I: Motor FunctionsW4 credits2V + 1UR. Riener, J. Duarte Barriga
Abstract“Rehabilitation engineering” is the application of science and technology to ameliorate the handicaps of individuals with disabilities in order to reintegrate them into society. The goal of this lecture is to present classical and new rehabilitation engineering principles and examples applied to compensate or enhance especially motor deficits.
ObjectiveProvide theoretical and practical knowledge of principles and applications used to rehabilitate individuals with motor disabilities.
Content“Rehabilitation” is the (re)integration of an individual with a disability into society. Rehabilitation engineering is “the application of science and technology to ameliorate the handicaps of individuals with disability”. Such handicaps can be classified into motor, sensor, and cognitive (also communicational) disabilities. In general, one can distinguish orthotic and prosthetic methods to overcome these disabilities. Orthoses support existing but affected body functions (e.g., glasses, crutches), while prostheses compensate for lost body functions (e.g., cochlea implant, artificial limbs). In case of sensory disorders, the lost function can also be substituted by other modalities (e.g. tactile Braille display for vision impaired persons).

The goal of this lecture is to present classical and new technical principles as well as specific examples applied to compensate or enhance mainly motor deficits. Modern methods rely more and more on the application of multi-modal and interactive techniques. Multi-modal means that visual, acoustical, tactile, and kinaesthetic sensor channels are exploited by displaying the patient with a maximum amount of information in order to compensate his/her impairment. Interaction means that the exchange of information and energy occurs bi-directionally between the rehabilitation device and the human being. Thus, the device cooperates with the patient rather than imposing an inflexible strategy (e.g., movement) upon the patient. Multi-modality and interactivity have the potential to increase the therapeutical outcome compared to classical rehabilitation strategies.
In the 1 h exercise the students will learn how to solve representative problems with computational methods applied to exoprosthetics, wheelchair dynamics, rehabilitation robotics and neuroprosthetics.
Lecture notesLecture notes will be distributed at the beginning of the lecture (1st session)
LiteratureIntroductory Books

Neural prostheses - replacing motor function after desease or disability. Eds.: R. Stein, H. Peckham, D. Popovic. New York and Oxford: Oxford University Press.

Advances in Rehabilitation Robotics – Human-Friendly Technologies on Movement Assistance and Restoration for People with Disabilities. Eds: Z.Z. Bien, D. Stefanov (Lecture Notes in Control and Information Science, No. 306). Springer Verlag Berlin 2004.

Intelligent Systems and Technologies in Rehabilitation Engineering. Eds: H.N.L. Teodorescu, L.C. Jain (International Series on Computational Intelligence). CRC Press Boca Raton, 2001.

Control of Movement for the Physically Disabled. Eds.: D. Popovic, T. Sinkjaer. Springer Verlag London, 2000.

Interaktive und autonome Systeme der Medizintechnik - Funktionswiederherstellung und Organersatz. Herausgeber: J. Werner, Oldenbourg Wissenschaftsverlag 2005.

Biomechanics and Neural Control of Posture and Movement. Eds.: J.M. Winters, P.E. Crago. Springer New York, 2000.

Selected Journal Articles

Abbas, J., Riener, R. (2001) Using mathematical models and advanced control systems techniques to enhance neuroprosthesis function. Neuromodulation 4, pp. 187-195.

Burdea, G., Popescu, V., Hentz, V., and Colbert, K. (2000): Virtual reality-based orthopedic telerehabilitation, IEEE Trans. Rehab. Eng., 8, pp. 430-432

Colombo, G., Jörg, M., Schreier, R., Dietz, V. (2000) Treadmill training of paraplegic patients using a robotic orthosis. Journal of Rehabilitation Research and Development, vol. 37, pp. 693-700.

Colombo, G., Jörg, M., Jezernik, S. (2002) Automatisiertes Lokomotionstraining auf dem Laufband. Automatisierungstechnik at, vol. 50, pp. 287-295.

Cooper, R. (1993) Stability of a wheelchair controlled by a human. IEEE Transactions on Rehabilitation Engineering 1, pp. 193-206.

Krebs, H.I., Hogan, N., Aisen, M.L., Volpe, B.T. (1998): Robot-aided neurorehabilitation, IEEE Trans. Rehab. Eng., 6, pp. 75-87

Leifer, L. (1981): Rehabilitive robotics, Robot Age, pp. 4-11

Platz, T. (2003): Evidenzbasierte Armrehabilitation: Eine systematische Literaturübersicht, Nervenarzt, 74, pp. 841-849

Quintern, J. (1998) Application of functional electrical stimulation in paraplegic patients. NeuroRehabilitation 10, pp. 205-250.

Riener, R., Nef, T., Colombo, G. (2005) Robot-aided neurorehabilitation for the upper extremities. Medical & Biological Engineering & Computing 43(1), pp. 2-10.

Riener, R., Fuhr, T., Schneider, J. (2002) On the complexity of biomechanical models used for neuroprosthesis development. International Journal of Mechanics in Medicine and Biology 2, pp. 389-404.

Riener, R. (1999) Model-based development of neuroprostheses for paraplegic patients. Royal Philosophical Transactions: Biological Sciences 354, pp. 877-894.
Prerequisites / NoticeTarget Group:
Students of higher semesters and PhD students of
- Biomedical Engineering
- Medical Faculty, University of Zurich
Students of other departments, faculties, courses are also welcome
376-1308-00LDevelopment Strategies for Medical Implants Restricted registration - show details
Number of participants limited to 25 until 30.
Assignments will be considered chronological.
W3 credits2V + 1UJ. Mayer-Spetzler, M. Rubert
AbstractIntroduction to development strategies for implantable devices considering the interdependecies of biocompatibility, clinical and economical requirements ; discussion of the state of the art and actual trends in in orthopedics, sports medicine, traumatology and cardio-vascular surgery as well as regenerative medicine (tissue engineering).
ObjectiveBasic considerations in implant development
Concept of structural and surface biocompatiblity and its relevance for the design of implant and surgical technique
Understanding of conflicting factors, e.g. clinical need, economics and regulatory requirements
Concepts of tissue engineering, its strengths and weaknesses as current and future clinical solution
ContentBiocompatibility as bionic guide line for the development of medical implants; implant and implantation related tissue reactions, biocompatible materials and material processing technologies; implant testing and regulatory procedures; discussion of the state of the art and actual trends in implant development in orthopedics, sports medicine, traumatology, spinal and cardio-vascular surgery; introduction to tissue engineering. Selected topics will be further illustrated by commented movies from surgeries.

Group seminars on selected controversial topics in implant development. Participation is mandatory

Planned excursions (limited availability, not mandatory, to be confirmed):
1. Participation (as visitor) on a life surgery (travel at own expense)
Lecture notesScribt (electronically available):
- presented slides
- selected scientific papers for further reading
LiteratureReference to key papers will be provided during the lectures
Prerequisites / NoticeAchieved Bachelor degree is mandatory

The number of participants in the course is limited to 25-30 students in total.

Students will be exposed to surgical movies which may cause emotional reactions. The viewing of the surgical movies is voluntary and is on the student's own responsability.
376-1392-00LMechanobiology: Implications for Development, Regeneration and Tissue EngineeringW3 credits2GA. Ferrari, K. Würtz-Kozak, M. Zenobi-Wong
AbstractThis course will emphasize the importance of mechanobiology to cell determination and behavior. Its importance to regenerative medicine and tissue engineering will also be addressed. Finally, this course will discuss how age and disease adversely alter major mechanosensitive developmental programs.
ObjectiveThis course is designed to illuminate the importance of mechanobiological processes to life as well as to teach good experimental strategies to investigate mechanobiological phenomena.
ContentTypically, cell differentiation is studied under static conditions (cells grown on rigid plastic tissue culture dishes in two-dimensions), an experimental approach that, while simplifying the requirements considerably, is short-sighted in scope. It is becoming increasingly apparent that many tissues modulate their developmental programs to specifically match the mechanical stresses that they will encounter in later life. Examples of known mechanosensitive developmental programs include osteogenesis (bones), chondrogenesis (cartilage), and tendogenesis (tendons). Furthermore, general forms of cell behavior such as migration, extracellular matrix deposition, and complex tissue differentiation are also regulated by mechanical stimuli. Mechanically-regulated cellular processes are thus ubiquitous, ongoing and of great clinical importance.

The overall importance of mechanobiology to humankind is illustrated by the fact that nearly 80% of our entire body mass arises from tissues originating from mechanosensitive developmental programs, principally bones and muscles. Unfortunately, our ability to regenerate mechanosensitive tissue diminishes in later life. As it is estimated that the fraction of the western world population over 65 years of age will double in the next 25 years, an urgency in the global biomedical arena exists to better understand how to optimize complex tissue development under physiologically-relevant mechanical environments for purposes of regenerative medicine and tissue engineering.
Lecture notesn/a
LiteratureTopical Scientific Manuscripts
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