Search result: Catalogue data in Spring Semester 2019

Health Sciences and Technology Bachelor Information
Electives
NumberTitleTypeECTSHoursLecturers
151-0641-00LIntroduction to Robotics and Mechatronics Information Restricted registration - show details
Number of participants limited to 60.

Enrollment is only valid through registration on the MSRL website (www.msrl.ethz.ch). Online registrations begin on the 1st of February 2019. Registrations per e-mail is no longer accepted!
W4 credits2V + 2UB. Nelson, N. Shamsudhin
AbstractThe aim of this lecture is to expose students to the fundamentals of mechatronic and robotic systems. Over the course of these lectures, topics will include how to interface a computer with the real world, different types of sensors and their use, different types of actuators and their use.
ObjectiveAn ever-increasing number of mechatronic systems are finding their way into our daily lives. Mechatronic systems synergistically combine computer science, electrical engineering, and mechanical engineering. Robotics systems can be viewed as a subset of mechatronics that focuses on sophisticated control of moving devices.

The aim of this course is to practically and theoretically expose students to the fundamentals of mechatronic and robotic systems. Over the course of the semester, the lecture topics will include an overview of robotics, an introduction to different types of sensors and their use, the programming of microcontrollers and interfacing these embedded computers with the real world, signal filtering and processing, an introduction to different types of actuators and their use, an overview of computer vision, and forward and inverse kinematics. Throughout the course, students will periodically attend laboratory sessions and implement lessons learned during lectures on real mechatronic systems. By the end of the course, you will be able to independently choose, design and integrate these different building blocks into a working mechatronic system.
ContentThe course consists of weekly lectures and lab sessions. The weekly topics are the following:
0. Course Introduction
1. C Programming
2. Sensors
3. Data Acquisition
4. Signal Processing
5. Digital Filtering
6. Actuators
7. Computer Vision and Kinematics
8. Modeling and Control
9. Review and Outlook

The lecture schedule can be found on our course page on the MSRL website (www.msrl.ethz.ch)
Prerequisites / NoticeThe students are expected to be familiar with C programming.
252-0842-00LIntroduction to Programming and Problem Solving Information Restricted registration - show details
Number of participants limited to 40.
W3 credits2V + 0.5UD. Komm
AbstractIntroduction to programming in Java and to problem solving using standard algorithms and data structures.
ObjectiveThe goals of this lecture are first, to become familiar with the programming language Java, and second, to be able to solve given problems of the student's subject area (for example data processing) with their own programs.

The students should know standard algorithms and data structures, they should know how to use them and also what properties the algorithms and data structures have. The goal is, that students are able to make a reasonable choice of algorithms and data structures for a given problem and that they can implement their own program to solve the given problem.

The students will work on an own project during the lecture. They will need to present the project during the last lecture.
ContentThe following topics will be covered:
- Programming concepts vs. programming languages
- Introduction to Java
- Arrays
- Methods and parameters
- Classes, types and objects
- I/O, using the keyboard and the screen, reading and writing files
- Exceptions
- Lambda Expressions and the Stream API
- Data structures
- Introduction to GUI programming
Lecture notesLecture website: http://lec.inf.ethz.ch/ppl
Prerequisites / NoticeAttention: This is a block-course that takes place only during the first seven weeks of the semester. These seven weeks are very intensive as the graded projekt is also being implemented during this time.

Recommendation:
- Application of software tools (252-0839-00)
- Application Oriented Programming Using Python (252-0840-01)
376-0012-00LPractical Course in Motor Control Information Restricted registration - show details W2 credits2GB. Mattli Baur, M.‑M. Jäggi
AbstractImpact of the sensory systems for motor learning / self-awareness of the different coordinative competencies / strategies to optimize motor actions / phase analysis of selected movements / motor quality / feedback
ObjectiveThe students should be able to:
1. recognise the diverse causes and aspects which affect the motor action competency
2. differentiate and classify the basic requirements of the muscular adaptive control with regard to its coordinative competences
3. recognise and oppose the various coordinative abilities to one another
4. deeply experience and specifically improve their own coordinative competences in typical examples particularly in the area of auto movement
5. get to know and implement different learning strategies into their own motor movements
ContentImpact of the sensory systems for motor learning / self-awareness of the different coordinative competencies / strategies to optimize motor actions / phase analysis of selected movements / motor quality / feedback
Lecture notesDuring the semester the documents, incl. references are steadily available electronically
376-0014-00LPractical Course in Motor Learning Information Restricted registration - show details W2 credits2GA. Krebs, A. Sonderegger
AbstractIntroduction to principles of workout theory / practical exercise experience in the fields of strength, endurance, speed, and motility / undergoing a complete workout cycle / specific methods such as intermitted workouts etc. / training in different environments / workout monitoring and performance tests
ObjectiveThe participants' practical experience of basic workout principles will enhance their competence in scheduling and structuring workout sessions and programs.
ContentIntroduction to principles of workout theory / practical exercise experience in the fields of strength, endurance, speed, and motility / undergoing a complete workout cycle / specific methods such as intermitted workouts etc. / training in different environments / workout monitoring and performance tests
376-0905-00LFunctional Anatomy Information W3 credits2VD. P. Wolfer, I. Amrein
AbstractIntroduction to the anatomy of the musculoskeletal with the goal to better understand movements and the mechanisms of injuries.
Objective- understanding the three-dimensional organization of the human musculoskeletal system
- correct use of anatomical nomenclature in the description of structure and function
- understanding the connections between morphology and normal function of the musculoskeletal system
- knowledge of selected mechanisms of injury in terms of the underlying anatomy
Content- Allgemeine Anatomie des Bewegungsapparates (Bindegewebe, Knochen, Gelenke, Muskeln)
- Becken und freie untere Extremität (Skelett, Gelenke, Muskeln)
- Wirbelsäule, Brustkorb, Bauchwand (Skelett, Gelenke, Muskeln)
- Schulter und freie obere Extremität (Skelett, Gelenke, Muskeln)
Literature- Gehrke T, Sportanatomie, Rowohlt Taschenbuch Verlag
- Weineck J, Sportanatomie, Spitta-Verlag
- Appel H-J, Stang-Voss C, Funktionelle Anatomie, Springer-Verlag
376-1120-00LPsychology of Work and Health - an IntroductionW2 credits2VO. Hämmig, S. T. Güntert
AbstractInsight and overview over the broad, interdisciplinary and applied research field of work and health. Focus mainly on psychosocial factors (strains, stressors, resources) of paid work and their effects on psychological and physical health and on satisfaction and motivation of employees.
ObjectiveParticipants are aware of the health-related relevance of (paid) work and know the involved disciplines and the most important research topics, problem areas and associations in the field of work and health. In particular they are familiar with the most important work-related health disorders and with the psychosocial factors (risk and protective factors) that influence health, and with the data sources and research methods in this research field.
ContentDie Lehrveranstaltung gibt eine Einführung in die arbeitsbezogene Gesundheitspsychologie (Occupational Health Psychology) und die Sozialepidemiologie, zweier präventiv ausgerichteter wissenschaftlicher Subdisziplinen der (angewandten) Psychologie und der Medizin, die sich mit dem Thema "Arbeit und Gesundheit" beschäftigen und dabei soziale und insbesondere psychosoziale Faktoren und Stressoren bei der Arbeit in ihrer Wirkung auf die Gesundheit der Beschäftigten untersuchen. Auf der Suche nach sozialen und v.a. arbeitsbezogenen Ursachen von gesundheitlicher Ungleichheit und von vielfältigen Gesundheitsproblemen oder Krankheiten wie Herz-Kreislauf-Erkrankungen, muskuloskelettale Beschwerden oder Burnoutsymptome und andere psychische Störungen werden wichtige arbeitspsychologische Konzepte und Konstrukte thematisiert. Dazu zählen gesundheitliche Risikofaktoren und Belastungen bei der Arbeit wie etwa Stress, mangelnder Handlungs- und Entscheidungsspielraum, berufliche Gratifikationskrisen, Rollenkonflikte und Vereinbarkeitsprobleme zwischen Erwerbs- und Privatleben usw. Zur Sprache kommen aber auch gesundheitliche Protektivfaktoren und Ressourcen bei der Arbeit wie Zeitautonomie oder soziale Unterstützung am Arbeitsplatz sowie positive, potenziell gesundheitsförderliche Aspekte und Formen der Arbeit wie Arbeitsengagement oder Freiwilligenarbeit.
376-1148-00LFrom Symptoms to the DiagnosisW1 credit1VW. O. Frey
AbstractThis lecture addresses students who have to deal with medical problems, such as for example heart-pain during bicacle loading. Finding the medical causes of the pain, defining its classification and the emergency aid are some of the aims of these lessons. Consolidated knowledge in physiology and anatomy is required.
ObjectiveThis lecture addresses students who have to deal with medical problems, such as for example heart-pain during bicacle loading. Finding the medical causes of the pain, defining its classification and the emergency aid are some of the aims of these lessons.
ContentFinding the medical causes of the pain, defining its classification and the emergency aid are some of the aims of these lessons.
LiteratureLebensqualität: Bewegung- Ernähurng- Erholung
ISBN 3-906466-22-1
Beiträge zur Gesundheitsförderung
v. Paolo C. Colombani, Walter O. Frey, Caspar Wenk
376-1175-00LThermoregulation and SportswearW1 credit1VR. M. Rossi
AbstractThis lecture deals with fundamentals of human thermoregulation and treats different topics as the heat transfer of the body, hyper- and hypothermia, acclimatisation as well as thermal comfort and clothing thermal physiology.
ObjectiveThe goal of this lecture is to show the thermoregulatory mechanisms to maintain the body in thermal balance, as well as to treat the different heat exchange mechanisms with the environment and to demonstrate how state-of-the-art sports apparel can help maintaining the performance of the athlete.
ContentAls homöothermes Wesen muss der Mensch seine Körperkerntemperatur in engen Grenzen um 37°C halten. Die Wärmeproduktion muss im Gleichgewicht zur Wärmeabgabe stehen. Der menschliche Körper besitzt verschiedene Mechanismen, um Temperaturschwankungen der Umgebung zu kompensieren, wie z.B. die Vasodilatation und –konstriktion, Schwitzen, oder Frostzittern. Zusätzlich kann die Wahl einer adäquaten Kleidung die Klimaspanne, bei welcher ein Überleben möglich ist, fast beliebig vergrössern.
Zudem werden Grundlagen der Bekleidungsphysiologie präsentiert, und gezeigt, wie funktionelle Bekleidung bei unterschiedlichen Sportarten die thermophysiologischen Funktionen des Körpers unterstützen kann.
Lecture noteswird jeweils vor der Vorlesung elektronisch zur Verfügung gestellt.
376-1582-00LAdvances in Translational Cancer ResearchW2 credits2VH. Nägeli
AbstractThe goal of this course is that students meet leading scientists in cancer research from the Zurich area and get the possibility to discuss with them their current advances. The focus will be on translational cancer research with applications in diagnosis and therapy.
ObjectiveStudents understand selected topic of translational cancer research. They gain insights into the methodology of leading cancer research scientist from the Zurich area.
ContentSelected topics of current translational cancer research at ETH, University, University Hospital and Childrens' Hospital Zurich. Examples: molecular cancer biomarkers, clinical studies, diagnostic imaging, radiotherapy, immunotherapy, management of metastasis, cancer viruses, new therapeutic strategies. The presentations are in English or German.
Lecture notesLecturers provide their presentations in the form of handouts.
LiteratureThe lecturers recommend specific publications for further reading.
Prerequisites / NoticePrevious attendance at the lecture 376-1581-00L, Krebs: Grundlagen, Ursachen und Therapie
376-1666-00LTraining and Coaching II Restricted registration - show details
Number of participants limited to 30.

Can be attended independently of Training and Coaching I (376-1665-00).
W3 credits2GO. Buholzer
AbstractTrainer/Coach as personality and Advisor/ Tutor:
Strengths and weaknesses are judged/ graded on the basis of the personality analysis (Integro model) and are done so by outside as well as self- analysis.
Tools/ skills which can be utilised in Training and/ or Coaching are developed.
ObjectiveTo obtain a personal competency in training and coaching
To reflect and work on a personal profile of competency and elaborate on the formulation of aims
To reflect on your own personality as a trainer and to recognise your strengths and weaknesses
To widen the self-competency in relation to your trainer personality and self-guidance
To experience practical examples
To elaborate on your competencies in relation to subjects such as communication, motivation and guidance
To discuss a chosen subject area
ContentTheorie: Persönlichkeitsprofil - Modelle
Selbst- und Fremdeinschätzung
Typologie und Flexibilität
Kompetenzfelder
Praxis:
Führungsphilosophie, Führen und Coachen im Training (Einzelathlet und Team)
Der Trainer und Coach im Wettkampf
Fallbeispiele erarbeiten und planen
Umsetzung an ausgewählten Beispielen
Konkrete Umsetzung an ausgewählten Beispielen
Lecture notesDie Unterlagen werden auf der Homepage zugänglich gemacht. Im Unterricht wird ein Skript abgegeben.
Prerequisites / NoticeSemesterstart
Die Informationsveranstaltung findet zu Beginn des Semesters statt. Die genauen Daten (Zeit/Ort) werden per Mail zugestellt. Diese Veranstaltung ist obligatorisch.

Zeit/Ort
Der Unterricht findet im Normalunterricht und in Blockveranstaltungen statt.

Planung
Die Planungsunterlagen werden zu Semesterbeginn abgegebenen, sind provisorisch und können vom Dozenten geändert werden.

Kosten
Für die abgebene Literatur, die Unterlagen und die Analyse wird ein Kostenbeitrag verrechnet.

Anwesenheit
Es wird während des Semesters vollständige Präsenz erwünscht. Einzelne Veranstaltungen sind obligatorsich.
376-1715-00LIntroduction to Sports and Exercise Therapy
Prerequisite: Successful participation in the course Practical Course in Motor Learning (376-0014-00L).
W2 credits2VK. Marschall
AbstractThe lecture provides a theoretical and practical introduction to sports and exercise therapy and forms the basis for a qualification as sports and exercise therapist.
ObjectiveThe students are familiar with the profession Sports and Exercise Therapist. They are familiar with political and psychological aspects of health in sports and exercise therapy and gain knowledge of basic quality management.
Students are able to apply models such as ICF and modification of health behavior in case studies.
ContentThe role of physical activity and exercise in the health care system of Switzerland; project management;
ICF International Classification of Functioning; indication, goal setting, assessments, evaluation, epidemiology, health models such as salutogenesis, Rokeach; health psychology
LiteratureSchüle/Huber: Grundlagen der Sport- und Bewegungstherapie, Deutscher Ärzteverlag, Köln 2012;
H.Deimel et al.: Neue aktive Wege in Prävention und Rehabilitation, Deutscher Ärzte-Verlag, Köln 2007
Prerequisites / NoticeRequirement:"Introduction of Exercise Therapy" passed or during the first half of FS 2019.
The course forms the starting point for a qualification as exercise therapist. Together with the courses "Basics of Sports and Exercise Therapy" and "Practical basics of Sports and Exercise Therapy" 3 it is recognised as basic level toward the certificate of advanced studies in sports and exercise therapy (equivalent to "Basismodul").
At the last day will be an open-book-test.
529-0732-00LProteins and LipidsW6 credits3GD. Hilvert
AbstractAn overview of the relationship between protein sequence, conformation and function.
ObjectiveOverview of the relationship between protein sequence, conformation and function.
ContentProteins, structures and properties, (bio)synthesis of polypeptides, protein folding and design, protein engineering, chemical modification of proteins, proteomics.
LiteratureGeneral Literature:
- T.E. Creighton: Proteins: Structures and Molecular Properties, 2nd Edition, H.W. Freeman and Company, New York, 1993.
- C. Branden, J. Tooze , Introduction to Protein Structure, Garland Publishing, New York, 1991.
- J. M. Berg, J. L. Tymoczko, L. Stryer: Biochemistry, 5th edition, H.W. Freeman and Company, New York, 2002.
- G.A. Petsko, D. Ringe: Protein Structure and Function, New Science Press Ltd., London, 2004.

Original Literature:
Citations from the original literature relevant to the individual lectures will be assigned weekly.
529-1024-00LPhysical Chemistry II (for Biology and Pharmacy) Information W4 credits2V + 1UR. Riek
AbstractKinetics of chemical and biochemical reactions, in particular catalyzed reactions. Surface- and transport-phenomena, characterization of open systems.
ObjectiveKnowledge on the basics of time dependent process in chemical and biological systems.
ContentGrundbegriffe: Stofftransport, Transport in kontinuierlichen Systemen, Wärmeleitung, Viskosität von Gasen, Laminare Strömung durch Rohre, Ionenleitfähigkeit, Elektrisch geladene Grenzflächen, Elektrophorese, Sedimentation im Zentrifugalfeld, Eigenschaften der Plasmamembran, Transport durch Membranen, Membranpotentiale Reaktionsgeschwindigkeitsgesetze, Elementarreaktionen und zusammengesetzte Reaktionen, Molekularität, Reaktionsordnung, Experimentelle Methoden der Reaktionskinetik. Einfache Theorie chemischer Reaktionen: Temperaturabhängigkeit der Gleichgewichtskonstante und Arrheniusgleichung, Stosstheorie, Reaktionsquerschnitte, Theorie des Übergangszustandes. Zusammengesetzte Reaktionen: Reaktionsmechanismen und komplexe kinetische Systeme, Näherungsverfahren. Enzymkinetik. Kinetik geladener Teilchen. Diffusion und diffusionskontrollierte Reaktionen.
Lecture notesHandouts werden in der Vorlesung verteilt
LiteratureAdam, G., Läuger, P., Stark, G., 2003: Physikalische Chemie und Biophysik, 4. Aufl., Springer Verlag, Berlin.
Prerequisites / NoticeVoraussetzungen: Physikalische Chemie I
535-0231-00LMedicinal Chemistry IIW2 credits2VJ. Hall
AbstractThe lectures give an overview of selected drugs and the molecular mechanisms underlying their therapeutic effects in disease. The historical and modern-day methods by which these drugs were discovered and developed are described. Structure-function relationships and the biophysical rules underlying ligand-target interactions will be discussed and illustrated with examples.
ObjectiveBasic understanding of therapeutic agents with respect to molecular, pharmacological and pharmaceutical properties.
ContentMolecular mechanisms of action of drugs. Structure function and biophysical basis of ligand-target interactions.
Lecture notesWill be provided electronically in parts before each individual lecture.
Literature- G.L. Patrick, "An Introduction to Medicinal Chemistry", 5th edition, Oxford University Press (2013)
- D. Steinhilber, M. Schubert-Zsilavecz, H.J. Roth, "Medizinische Chemie", Deutscher Apotheker Verlag Stuttgart (2005)
- J.H. Block, J.M. Beale, "Organic Medicinal and Pharmaceutical Chemistry", 11th edition, Lippincott, Williams, Wilkins (2002)
- A. Gringauz, "How Drugs Act and Why", Wiley (1997)
- R. Silverman and M. Holladay, "The Organic Chemistry of Drug Design and Drug Action" 3rd Edition, Academic Press, (2014)
Prerequisites / NoticeRequirements: Knowledge of physical and organic chemistry, biochemistry and biology; Medicinal Chemistry I.
535-0241-03LBiopharmacyW3 credits3VS.‑D. Krämer
AbstractIntroduction to the Basics in Biopharmacy. Pharmacokinetic processes (absorption, distribution, metabolism and excretion, ADME), which determine the fate of a drug in the body. Knowledge of the most important pharmacokinetic parameters. Interpretation of concentration-time-profiles of drugs. Pharmacokinetic profiling of drugs in view of therapy optimization and analysis of interaction potential.
ObjectiveIntroduction to the Basics in Biopharmacy. Pharmacokinetic processes (absorption, distribution, metabolism and excretion, ADME), which determine the fate of a drug in the body. Knowledge of the most important pharmacokinetic parameters. Interpretation of concentration-time-profiles of drugs. Pharmacokinetic profiling of drugs in view of therapy optimization and analysis of interaction potential.
ContentIntroduction to pharmacokinetics; definition of the most important pharmacokinetic parameters and their calculation from clinical data (compartment model, statistical model); kinetics of absorption (absorption profiles); distribution of drugs and role of protein binding; kinetics of elimination: excretion and biotransformation (physiological model); pharmacokinetic profiling of drugs for therapy optimization and for the analysis of the interaction potential; dosage regimen design.
LiteratureP. Langguth, G. Fricker, H. Wunderli-Allenspach "Biopharmazie", Wiley-VCH Verlag, Weinheim, 2004.
535-0422-00LGalenical Pharmacy IIW2 credits2GJ.‑C. Leroux, B. A. Gander
AbstractContinues Galenical Pharmacy I. Powder technology. Tablets and tabletting. Coating technologies. Drug dissolution and release. Hard and soft gelatin capsules. Suppositories. Introduction to drug delivery and targeting. Drug delivery systems for peroral, transdermal, parenteral and mucosal administration.
ObjectiveIntroduction and overview of important fundamentals, principles and technologies for the development and manufacturing of dosage forms and drug delivery systems. In continuation of Galenical Pharmacy I. The students dispose of knowledge of properties, function, quality and application of dosage forms. The following topics will be covered: Powder technology. Tablets and tabletting. Coating technologies. Drug dissolution and release. Hard and soft gelatin capsules. Suppositories. Introduction to drug delivery and targeting. Drug delivery systems for peroral, transdermal, parenteral and mucosal administration. Formulation of biotechnology products.
ContentOverview of important fundamentals, principles and technologies for the development and manufacturing of solid dosage forms and drug delivery systems. Powder technology. Tablets and tabletting. Coating technologies. Drug dissolution and release. Hard and soft gelatin capsules. Introduction to drug delivery and targeting. Drug delivery systems for peroral, transdermal, parenteral and mucosal administration.
Lecture notesScripts, documentations to the lectures and additional supporting materials can be either downloaded via the indicated link to the course , or they will be directly provided at each lecture.
LiteratureA.T. Florence - An introduction to clinical pharmaceutics. Pharmaceutical Press, London 2010.
L.V. Allen, N.G. Popovich, H.C. Ansel, Ansel's Pharmaceutical Dosage Forms and Drug Delivery Systems, 10th Ed, Lippincott Williams & Wilkins, Baltimore 2014.
L. Felton, Remington - Essentials of Pharmaceutics, Pharmaceutical Press, London, 2013.
M.E. Aulton. Pharmaceutics - The design and manufacture of medicines. 5th Ed. Elsevier, Philadelphia, 2017.
Sinko P.J., Martin's Physical Pharmacy and Pharmaceutical Sciences, 7th ed, Wolters Kluwer, Philadelphia, 2017.
Prerequisites / NoticePrior attendance of Galenical Pharmacy I is recommended.
535-0522-00LPharmacology and Toxicology IIW2 credits2VU. Quitterer
AbstractThe two-semester lecture course will provide a basic understanding of mechanisms of drug action, pharmacological properties and therapeutic uses of important classes of drugs. The lectures are intended for students of pharmacy and health sciences.
ObjectiveThe lectures will provide a comprehensive survey of pharmacology and toxicology. Special emphasis is placed on the interrelationship between pharmacological, pathophysiological and clinical aspects.
ContentTopics include disease-relevant macroscopic, microscopic, pathobiochemical and functional disturbances of specific organs and organ systems. The lectures integrate disease pathology with mechanisms of drug action, usage, pharmacokinetics, side effects, toxicology, contraindications and dosage of relevant drug classes. Basic principles of clinical pharmacology and pharmacotherapy will be covered.
Lecture notesA script is provided for each lecture, which contains major contents of the lecture and defines exam-relevant topics. The scripts do not replace the lectures.
LiteratureKlaus Aktories, Ulrich Förstermann, Franz Hofmann, Klaus Starke.
Allgemeine und spezielle Pharmakologie und Toxikologie.
12. Auflage, 1146 Seiten
2017
Urban & Fischer Verlag/Elsevier GmbH,
ISBN-10: 3437425250; ISBN-13: 978-3437425257


The classic textbook on pharmacology:
Goodman & Gilman`s The Pharmacological Basis of Therapeutics.
Laurence Brunton, Björn Knollmann, Randa Hilal-Dandan
13th edition, 1440 pages
2017; McGraw - Hill Education
ISBN-10: 1259584739
ISBN-13: 978-1259584732
Prerequisites / NoticeAbschluss Grundstudium.

Gleichzeitiger oder vorgängiger Besuch des Seminars 535-0523-00 Aktuelle Themen aus Pharmakologie und Toxikologie ist dringend empfohlen.
535-0534-00LDrug, Society and Public HealthW1 credit1VJ. Steurer, R. Heusser
AbstractIntroduction of basic concepts and methods in Public Health, epidemiology, and Evidence Based Medicine. An overview on concepts and principles of clinical trials on efficacy of drugs
ObjectiveStudents know the concepts and principles of epidemiological and clinical research, they are informed about the principles of evidence based medicine and know how and where to search for evidence.
ContentEinführung in Epidemiologie / Pharmakoepidemiologie / Evidence-based Medicine: Grundbegriffe, Studiendesigns, object-design, statistische Grundlagen, Kausalität in der Pharmako-Epidemiologie, Methoden und Konzepte, Fallbeispiele.
Lecture notesWird abgegeben
Literature- F. Gutzwiller/ F. Paccaud (Hrsg.): Sozial- und Präventivmedizin - Public Health. 4. Aufl. 2011, Verlag Hans Huber, Bern
- R. Beaglehole, R. Bonita, T. Kjellström: Einführung in die Epidemiologie. 1997, Verlag Hans Huber, Bern
- L. Gordis: Epidemiology, 4 th Ed. 2009, W.B. Saunders Comp.
- K.J. Rothman, S. Greenland: Modern Epidemiology, 2. Ed. 1998, Lippincott Williams & Wilkins
- A.G. Hartzema, M. Porta, H.H. Tilson (Eds.): Pharmacoepidemiology - An Introduction. 3. Ed. Harvey Whitney Comp., Cincinnati
- R. Bonita, R. Beaglehole. Einführung in die Epidemiologie, 2. überarbeitete Auflage, 2008 Huber Verlag.
- B.L. Strom (Eds.): Pharmacoepidemiology. 3. Ed. 2000, Wiley & Sons Ltd., Chichester
- S.E. Straus, W.S. Richardson, P.Glasziou, R.B. Haynes: Evidence-based Medicine. 2005, Churchill Livingstone, London
- U. Jaehde, R.Radziwill, S. Mühlebach, W. Schnack (Hrsg): Lehrbuch der Klinischen Pharmazie
- L.M. Bachmann, M.A. Puhan, J.Steurer (Eds.): Patientenorientierte Forschung. EInführung in die Planung und Durchführung einer Studie. Verlag Hans Huber, 2008
551-0318-00LImmunology IIW3 credits2VA. Oxenius, M. Kopf, S. R. Leibundgut, E. Wetter Slack, further lecturers
AbstractIntroduction into the cellular and molecular basis of the immune system and immune responses against diverse pathogens, tumors, transplants, and self (autoimmunity)
ObjectiveThe lectures will provide a detailed understanding:
- how innate and adaptive immune responses interact at the cellular and molecular level.
- how the immune system recognizes and fights against pathogenic microorganisms including viruses, bacteria, and parasites.
- why lymphocytes tolerate self molecules.
- about function and dysfunction the intestinal immune system.
- immunopathology and inflammatory diseases.
ContentThe aim of lecture is to understand:
> How pathogens are recognized by the innate immune system
> Immune defense against various pathogens
> Immunology of the skin, lung and intestines
> Tumor immunology
> Migration and homing of immune cells
> tolerance and autoimmunity
> T cell memory
Lecture notesPresentations of the lecturers are available at the Moodle link
LiteratureRecommended: Kuby Immunology (Freeman)
551-0320-00LCellular Biochemistry (Part II)W3 credits2VY. Barral, R. Kroschewski, A. E. Smith
AbstractThis course will focus on molecular mechanisms and concepts underlying cellular biochemistry, providing advanced insights into the structural and functional details of individual cell components, and the complex regulation of their interactions. Particular emphasis will be on the spatial and temporal integration of different molecules and signaling pathways into global cellular processes.
ObjectiveThe full-year course (551-0319-00 & 551-0320-00) focuses on the molecular mechanisms and concepts underlying the biochemistry of cellular physiology, investigating how these processes are integrated to carry out highly coordinated cellular functions. The molecular characterization of complex cellular functions requires a combination of approaches such as biochemistry, but also cell biology and genetics. This course is therefore the occasion to discuss these techniques and their integration in modern cellular biochemistry.
The students will be able to describe the structural and functional details of individual cell components, and the spatial and temporal regulation of their interactions. In particular, they will learn to explain how different molecules and signaling pathways can be integrated during complex and highly dynamic cellular processes such as intracellular transport, cytoskeletal rearrangements, cell motility, and cell division. In addition, they will be able to illustrate the relevance of particular signaling pathways for cellular pathologies such as cancer or during cellular infection.
ContentSpatial and temporal integration of different molecules and signaling pathways into global cellular processes, such as cell division, cell infection and cell motility. Emphasis is also put on the understanding of pathologies associated with defective cell physiology, such as cancer or during cellular infection.
LiteratureRecommended supplementary literature (review articles and selected primary literature) will be provided during the course.
Prerequisites / NoticeTo attend this course the students must have a solid basic knowledge in chemistry, biochemistry, cell biology and general biology. Biology students have in general already attended the first part of the "Cellular Biochemistry" concept course (551-0319-00). The course will be taught in English.
In addition, the course will be based on a blended-learning scenario, where frontal lectures will be complemented with carefully chosen web-based teaching elements that students access through the ETH Moodle platform.
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