Search result: Catalogue data in Spring Semester 2021
Biology Master | ||||||
Elective Major Subject Areas | ||||||
Elective Major: Neurosciences The major in Neurosciences in the Master program Biology ETHZ will no longer be offered from autumn 2019 onwards. | ||||||
Elective Compulsory Concept Courses See D-BIOL Master Studies Guide | ||||||
Number | Title | Type | ECTS | Hours | Lecturers | |
---|---|---|---|---|---|---|
551-0318-00L | Immunology II | W | 3 credits | 2V | A. Oxenius, M. Kopf, S. R. Leibundgut, E. Slack, further lecturers | |
Abstract | Introduction into the cellular and molecular basis of the immune system and immune responses against diverse pathogens, tumors, transplants, and self (autoimmunity) | |||||
Objective | The lectures will provide a detailed understanding: - how innate and adaptive immune responses interact at the cellular and molecular level. - how the immune system recognizes and fights against pathogenic microorganisms including viruses, bacteria, and parasites. - why lymphocytes tolerate self molecules. - about function and dysfunction the intestinal immune system. - immunopathology and inflammatory diseases. | |||||
Content | The aim of lecture is to understand: > How pathogens are recognized by the innate immune system > Immune defense against various pathogens > Immunology of the skin, lung and intestines > Tumor immunology > Migration and homing of immune cells > tolerance and autoimmunity > T cell memory | |||||
Lecture notes | Presentations of the lecturers are available at the Moodle link | |||||
Literature | Recommended: Kuby Immunology (Freeman) | |||||
551-0320-00L | Cellular Biochemistry (Part II) | W | 3 credits | 2V | Y. Barral, R. Kroschewski, A. E. Smith | |
Abstract | This course will focus on molecular mechanisms and concepts underlying cellular biochemistry, providing advanced insights into the structural and functional details of individual cell components, and the complex regulation of their interactions. Particular emphasis will be on the spatial and temporal integration of different molecules and signaling pathways into global cellular processes. | |||||
Objective | The full-year course (551-0319-00 & 551-0320-00) focuses on the molecular mechanisms and concepts underlying the biochemistry of cellular physiology, investigating how these processes are integrated to carry out highly coordinated cellular functions. The molecular characterization of complex cellular functions requires a combination of approaches such as biochemistry, but also cell biology and genetics. This course is therefore the occasion to discuss these techniques and their integration in modern cellular biochemistry. The students will be able to describe the structural and functional details of individual cell components, and the spatial and temporal regulation of their interactions. In particular, they will learn to explain how different molecules and signaling pathways can be integrated during complex and highly dynamic cellular processes such as intracellular transport, cytoskeletal rearrangements, cell motility, and cell division. In addition, they will be able to illustrate the relevance of particular signaling pathways for cellular pathologies such as cancer or during cellular infection. | |||||
Content | Spatial and temporal integration of different molecules and signaling pathways into global cellular processes, such as cell division, cell infection and cell motility. Emphasis is also put on the understanding of pathologies associated with defective cell physiology, such as cancer or during cellular infection. | |||||
Literature | Recommended supplementary literature may be provided during the course. | |||||
Prerequisites / Notice | To attend this course the students must have a solid basic knowledge in chemistry, biochemistry, cell biology and general biology. Biology students have in general already attended the first part of the "Cellular Biochemistry" concept course (551-0319-00). The course will be taught in English. In addition, the course will be based on a blended-learning scenario, where frontal lectures will be complemented with carefully chosen web-based teaching elements that students access through the ETH Moodle platform. | |||||
Elective Compulsory Master Courses | ||||||
Number | Title | Type | ECTS | Hours | Lecturers | |
227-1034-00L | Computational Vision (University of Zurich) No enrolment to this course at ETH Zurich. Book the corresponding module directly at UZH. UZH Module Code: INI402 Mind the enrolment deadlines at UZH: Link | W | 6 credits | 2V + 1U | D. Kiper | |
Abstract | This course focuses on neural computations that underlie visual perception. We study how visual signals are processed in the retina, LGN and visual cortex. We study the morpholgy and functional architecture of cortical circuits responsible for pattern, motion, color, and three-dimensional vision. | |||||
Objective | This course considers the operation of circuits in the process of neural computations. The evolution of neural systems will be considered to demonstrate how neural structures and mechanisms are optimised for energy capture, transduction, transmission and representation of information. Canonical brain circuits will be described as models for the analysis of sensory information. The concept of receptive fields will be introduced and their role in coding spatial and temporal information will be considered. The constraints of the bandwidth of neural channels and the mechanisms of normalization by neural circuits will be discussed. The visual system will form the basis of case studies in the computation of form, depth, and motion. The role of multiple channels and collective computations for object recognition will be considered. Coordinate transformations of space and time by cortical and subcortical mechanisms will be analysed. The means by which sensory and motor systems are integrated to allow for adaptive behaviour will be considered. | |||||
Content | This course considers the operation of circuits in the process of neural computations. The evolution of neural systems will be considered to demonstrate how neural structures and mechanisms are optimised for energy capture, transduction, transmission and representation of information. Canonical brain circuits will be described as models for the analysis of sensory information. The concept of receptive fields will be introduced and their role in coding spatial and temporal information will be considered. The constraints of the bandwidth of neural channels and the mechanisms of normalization by neural circuits will be discussed. The visual system will form the basis of case studies in the computation of form, depth, and motion. The role of multiple channels and collective computations for object recognition will be considered. Coordinate transformations of space and time by cortical and subcortical mechanisms will be analysed. The means by which sensory and motor systems are integrated to allow for adaptive behaviour will be considered. | |||||
Literature | Books: (recommended references, not required) 1. An Introduction to Natural Computation, D. Ballard (Bradford Books, MIT Press) 1997. 2. The Handbook of Brain Theorie and Neural Networks, M. Arbib (editor), (MIT Press) 1995. | |||||
227-1046-00L | Computer Simulations of Sensory Systems | W | 3 credits | 3G | T. Haslwanter | |
Abstract | This course deals with computer simulations of the human auditory, visual, and balance system. The lecture will cover the physiological and mechanical mechanisms of these sensory systems. And in the exercises, the simulations will be implemented with Python. The simulations will be such that their output could be used as input for actual neuro-sensory prostheses. | |||||
Objective | Our sensory systems provide us with information about what is happening in the world surrounding us. Thereby they transform incoming mechanical, electromagnetic, and chemical signals into “action potentials”, the language of the central nervous system. The main goal of this lecture is to describe how our sensors achieve these transformations, how they can be reproduced with computational tools. For example, our auditory system performs approximately a “Fourier transformation” of the incoming sound waves; our early visual system is optimized for finding edges in images that are projected onto our retina; and our balance system can be well described with a “control system” that transforms linear and rotational movements into nerve impulses. In the exercises that go with this lecture, we will use Python to reproduce the transformations achieved by our sensory systems. The goal is to write programs whose output could be used as input for actual neurosensory prostheses: such prostheses have become commonplace for the auditory system, and are under development for the visual and the balance system. For the corresponding exercises, at least some basic programing experience is required!! | |||||
Content | The following topics will be covered: • Introduction into the signal processing in nerve cells. • Introduction into Python. • Simplified simulation of nerve cells (Hodgkins-Huxley model). • Description of the auditory system, including the application of Fourier transforms on recorded sounds. • Description of the visual system, including the retina and the information processing in the visual cortex. The corresponding exercises will provide an introduction to digital image processing. • Description of the mechanics of our balance system, and the “Control System”-language that can be used for an efficient description of the corresponding signal processing (essentially Laplace transforms and control systems). | |||||
Lecture notes | For each module additional material will be provided on the e-learning platform "moodle". The main content of the lecture is also available as a wikibook, under Link | |||||
Literature | Open source information is available as wikibook Link For good overviews of the neuroscience, I recommend: • Principles of Neural Science (5th Ed, 2012), by Eric Kandel, James Schwartz, Thomas Jessell, Steven Siegelbaum, A.J. Hudspeth ISBN 0071390111 / 9780071390118 THE standard textbook on neuroscience. NOTE: The 6th edition will be released on February 5, 2021! • L. R. Squire, D. Berg, F. E. Bloom, Lac S. du, A. Ghosh, and N. C. Spitzer. Fundamental Neuroscience, Academic Press - Elsevier, 2012 [ISBN: 9780123858702]. This book covers the biological components, from the functioning of an individual ion channels through the various senses, all the way to consciousness. And while it does not cover the computational aspects, it nevertheless provides an excellent overview of the underlying neural processes of sensory systems. • G. Mather. Foundations of Sensation and Perception, 2nd Ed Psychology Press, 2009 [ISBN: 978-1-84169-698-0 (hardcover), oder 978-1-84169-699-7 (paperback)] A coherent, up-to-date introduction to the basic facts and theories concerning human sensory perception. • The best place to get started with Python programming are the Link On signal processing with Python, my upcoming book • Hands-on Signal Analysis with Python (Due: January 13, 2021 ISBN 978-3-030-57902-9, Link) will contain an explanation to all the required programming tools and packages. | |||||
Prerequisites / Notice | • Since I have to gravel from Linz, Austria, to Zurich to give this lecture, I plan to hold this lecture in blocks (every 2nd week). • In addition to the lectures, this course includes external lab visits to institutes actively involved in research on the relevant sensory systems. | |||||
227-0390-00L | Elements of Microscopy | W | 4 credits | 3G | M. Stampanoni, G. Csúcs, A. Sologubenko | |
Abstract | The lecture reviews the basics of microscopy by discussing wave propagation, diffraction phenomena and aberrations. It gives the basics of light microscopy, introducing fluorescence, wide-field, confocal and multiphoton imaging. It further covers 3D electron microscopy and 3D X-ray tomographic micro and nanoimaging. | |||||
Objective | Solid introduction to the basics of microscopy, either with visible light, electrons or X-rays. | |||||
Content | It would be impossible to imagine any scientific activities without the help of microscopy. Nowadays, scientists can count on very powerful instruments that allow investigating sample down to the atomic level. The lecture includes a general introduction to the principles of microscopy, from wave physics to image formation. It provides the physical and engineering basics to understand visible light, electron and X-ray microscopy. During selected exercises in the lab, several sophisticated instrument will be explained and their capabilities demonstrated. | |||||
Literature | Available Online. | |||||
376-1306-00L | Clinical Neuroscience (University of Zurich) No enrolment to this course at ETH Zurich. Book the corresponding module directly at UZH. UZH Module Code: BIO389 Mind the enrolment deadlines at UZH: Link | W | 3 credits | 3V | G. Schratt, University lecturers | |
Abstract | The lecture series "Clinical Neuroscience" presents a comprehensive, condensed overview of the most important neurological diseases, their clinical presentation, diagnosis, therapy options and possible causes. Patient demonstrations (Übungen) follow every lecture that is dedicated to a particular disease. | |||||
Objective | By the end of this module students should be able to: - demonstrate their understanding and deep knowledge concerning the main neurological diseases - identify and explain the different clinical presentation of these diseases, the methodology of diagnosis and the current therapies available - summarize and critically review scientific literature efficiently and effectively | |||||
376-1414-01L | Current Topics in Brain Research (FS) | W | 1 credit | 1.5K | I. Mansuy, F. Helmchen, further lecturers | |
Abstract | Different national and international scientific guests are invited to present and discuss their most recent scientific results. | |||||
Objective | The aim is to exchange scientific knowledge and data as well as to promote communication and collaboration among researchers. Students taking the course participate in all seminars within one semester and write a critical report about one seminar of their choice. Prof. Isabelle / Dr. Alberto Corcoba will send instructions for this report to students who have registered for the course one week before the start of the semester. | |||||
Content | Various scientific guests from the fields of neuroepigenetics, neurochemistry, neuromorphology and neurophysiology will report on their latest scientific findings. | |||||
Lecture notes | no handout | |||||
Literature | no literature | |||||
Elective Concept Courses | ||||||
Number | Title | Type | ECTS | Hours | Lecturers | |
551-0326-00L | Cell Biology | W | 6 credits | 4V | S. Werner, H. Gehart, W. Kovacs, M. Schäfer, U. Suter, A. Wutz, further lecturers | |
Abstract | This Course introduces principle concepts, techniques, and experimental strategies used in modern Cell Biology. Major topics include: neuron-glia interactions in health and disease; mitochondrial dynamics; stem cell biology; growth factor action in development, tissue repair and disease; cell metabolism, in particular sensing and signaling mechanisms, cell organelles, and lipid metabolism. | |||||
Objective | -To prepare the students for successful and efficient lab work by learning how to ask the right questions and to use the appropriate techniques in a research project. -To convey knowledge about neuron-glia interactions in health and disease. - To provide information on different types of stem cells and their function in health and disease -To provide information on growth factor signaling in development, repair and disease and on the use of growth factors or their receptors as drug targets for major human diseases -To convey knowledge on the mechanisms underlying repair of injured tissues -To provide the students with an overview of mitochondrial dynamics. -Providing an understanding of RNA processing reactions and their regulations. -To provide a comprehensive understanding of metabolic sensing mechanisms occurring in different cell types and organelles in response to glucose, hormones, oxygen, nutrients as well as lipids, and to discuss downstream signaling pathways and cellular responses. -To provide models explaining how disturbances in complex metabolic control networks and bioenergetics can lead to disease and to highlight latest experimental approaches to uncover the intricacies of metabolic control at the cellular and organismal level. -Providing the background and context that foster cross-disciplinary scientific thinking. | |||||
551-0318-00L | Immunology II | W | 3 credits | 2V | A. Oxenius, M. Kopf, S. R. Leibundgut, E. Slack, further lecturers | |
Abstract | Introduction into the cellular and molecular basis of the immune system and immune responses against diverse pathogens, tumors, transplants, and self (autoimmunity) | |||||
Objective | The lectures will provide a detailed understanding: - how innate and adaptive immune responses interact at the cellular and molecular level. - how the immune system recognizes and fights against pathogenic microorganisms including viruses, bacteria, and parasites. - why lymphocytes tolerate self molecules. - about function and dysfunction the intestinal immune system. - immunopathology and inflammatory diseases. | |||||
Content | The aim of lecture is to understand: > How pathogens are recognized by the innate immune system > Immune defense against various pathogens > Immunology of the skin, lung and intestines > Tumor immunology > Migration and homing of immune cells > tolerance and autoimmunity > T cell memory | |||||
Lecture notes | Presentations of the lecturers are available at the Moodle link | |||||
Literature | Recommended: Kuby Immunology (Freeman) | |||||
551-0320-00L | Cellular Biochemistry (Part II) | W | 3 credits | 2V | Y. Barral, R. Kroschewski, A. E. Smith | |
Abstract | This course will focus on molecular mechanisms and concepts underlying cellular biochemistry, providing advanced insights into the structural and functional details of individual cell components, and the complex regulation of their interactions. Particular emphasis will be on the spatial and temporal integration of different molecules and signaling pathways into global cellular processes. | |||||
Objective | The full-year course (551-0319-00 & 551-0320-00) focuses on the molecular mechanisms and concepts underlying the biochemistry of cellular physiology, investigating how these processes are integrated to carry out highly coordinated cellular functions. The molecular characterization of complex cellular functions requires a combination of approaches such as biochemistry, but also cell biology and genetics. This course is therefore the occasion to discuss these techniques and their integration in modern cellular biochemistry. The students will be able to describe the structural and functional details of individual cell components, and the spatial and temporal regulation of their interactions. In particular, they will learn to explain how different molecules and signaling pathways can be integrated during complex and highly dynamic cellular processes such as intracellular transport, cytoskeletal rearrangements, cell motility, and cell division. In addition, they will be able to illustrate the relevance of particular signaling pathways for cellular pathologies such as cancer or during cellular infection. | |||||
Content | Spatial and temporal integration of different molecules and signaling pathways into global cellular processes, such as cell division, cell infection and cell motility. Emphasis is also put on the understanding of pathologies associated with defective cell physiology, such as cancer or during cellular infection. | |||||
Literature | Recommended supplementary literature may be provided during the course. | |||||
Prerequisites / Notice | To attend this course the students must have a solid basic knowledge in chemistry, biochemistry, cell biology and general biology. Biology students have in general already attended the first part of the "Cellular Biochemistry" concept course (551-0319-00). The course will be taught in English. In addition, the course will be based on a blended-learning scenario, where frontal lectures will be complemented with carefully chosen web-based teaching elements that students access through the ETH Moodle platform. | |||||
Elective Major: Microbiology and Immunology | ||||||
Compulsory Concept Courses | ||||||
Number | Title | Type | ECTS | Hours | Lecturers | |
551-0314-00L | Microbiology (Part II) | O | 3 credits | 2V | W.‑D. Hardt, L. Eberl, J. Piel, J. Vorholt-Zambelli | |
Abstract | Advanced lecture class providing a broad overview on bacterial cell structure, genetics, metabolism, symbiosis and pathogenesis. | |||||
Objective | This concept class will be based on common concepts and introduce to the enormous diversity among bacteria and archaea. It will cover the current research on bacterial cell structure, genetics, metabolism, symbiosis and pathogenesis. | |||||
Content | Advanced class covering the state of the research in bacterial cell structure, genetics, metabolism, symbiosis and pathogenesis. | |||||
Lecture notes | Updated handouts will be provided during the class. | |||||
Literature | Current literature references will be provided during the lectures. | |||||
Prerequisites / Notice | English | |||||
551-0318-00L | Immunology II | O | 3 credits | 2V | A. Oxenius, M. Kopf, S. R. Leibundgut, E. Slack, further lecturers | |
Abstract | Introduction into the cellular and molecular basis of the immune system and immune responses against diverse pathogens, tumors, transplants, and self (autoimmunity) | |||||
Objective | The lectures will provide a detailed understanding: - how innate and adaptive immune responses interact at the cellular and molecular level. - how the immune system recognizes and fights against pathogenic microorganisms including viruses, bacteria, and parasites. - why lymphocytes tolerate self molecules. - about function and dysfunction the intestinal immune system. - immunopathology and inflammatory diseases. | |||||
Content | The aim of lecture is to understand: > How pathogens are recognized by the innate immune system > Immune defense against various pathogens > Immunology of the skin, lung and intestines > Tumor immunology > Migration and homing of immune cells > tolerance and autoimmunity > T cell memory | |||||
Lecture notes | Presentations of the lecturers are available at the Moodle link | |||||
Literature | Recommended: Kuby Immunology (Freeman) | |||||
Elective Compulsory Master Courses | ||||||
Number | Title | Type | ECTS | Hours | Lecturers | |
701-1310-00L | Environmental Microbiology | W | 3 credits | 2V | M. H. Schroth, M. Lever | |
Abstract | Microorganisms catalyze a large number of reactions that are of great importance to terrestrial and aquatic environments. To improve our understanding of the dynamics of a specific environment, it is important to gain a better understanding of microbial structures and their functions under varying environmental conditions. | |||||
Objective | Students will learn basic concepts in microbial ecology. Qualitative and quantitative concepts will be presented to assess microbial communities and associated processes in terrestrial and aquatic environments. Microbial diversity in such ecosystems will be illustrated in discussions of selected habitats. | |||||
Content | Lectures will cover general concepts of environmental microbiology including (i) quantification of microbial processes, (ii) energy fluxes in microbial ecosystems, (iii) application of state-of-the-art microbiological and molecular tools, and (iv) use of isotope methods for identification of microbial structures and functions. Topics to illustrate the microbial diversity of terrestrial and aquatic ecosystems will include (i) interactions between microbes and mineral/metallic solid phases, (ii) microbial carbon and nutrient cycling, (iii) microbial processes involved in the turnover of greenhouse gases, (iv) biofilms and microbial mats, (v) bioremediation, (vi) microorganisms in extreme habitats, and (vii) microbial evolution and astrobiology. | |||||
Lecture notes | available at time of lecture - will be distributed electronically as pdf's | |||||
Literature | Brock Biology of Microorganisms, Madigan M. et al., Pearson, 14th ed., 2015 | |||||
551-1100-00L | Infectious Agents: From Molecular Biology to Disease Number of participants limited to 22. Requires application until 2 weeks before the start of the semester; selected applicants will be notified one week before the first week of lectures. (if you missed the deadline, please come to the first date to see, if there are any slots left) | W | 4 credits | 2S | W.‑D. Hardt, A. B. Hehl, M. Kopf, S. R. Leibundgut, C. Münz, A. Oxenius, P. Sander, further lecturers | |
Abstract | Literature seminar for students at the masters level and PhD students. Introduction to the current research topics in infectious diseases; Introduction to key pathogens which are studied as model organisms in this field; Overview over key research groups in the field of infectious diseases in Zürich. | |||||
Objective | Working with the current research literature. Getting to know the key pathogens serving as model organisms and the research technologies currently used in infection biology. | |||||
Content | for each model pathogen (or key technology): 1. introduction to the pathogen 2. Discussion of one current research paper. The paper will be provided by the respective supervisor. He/she will give advice (if required) and guide the respective literature discussion. | |||||
Lecture notes | Teachers will provide the research papers to be discussed. Students will prepare handouts for the rest of the group for their assigned seminar. | |||||
Literature | Teachers will provide the research papers to be discussed. | |||||
Prerequisites / Notice | Restricted to max 22 students. Please sign up until two weeks before the beginning of the semester via e-mail to Link and include the following information: 551-1100-00L; your name, your e-mail address, university/eth, students (specialization, semester), PhD students (research group, member of a PhD program? which program?). The 22 students admitted to this seminar will be selected and informed by e-mail in the week befor the beginning of the semester by W.-D. Hardt. The first seminar date will serve to form groups of students and assign a paper to each group. | |||||
551-1118-00L | Cutting Edge Topics: Immunology and Infection Biology II | W | 2 credits | 2S | A. Oxenius, B. Becher, C. Halin Winter, N. C. Joller, M. Kopf, S. R. Leibundgut, C. Münz, F. Sallusto, R. Spörri, M. van den Broek, University lecturers | |
Abstract | Weekly seminar about cutting edge topics in immunology and infection biology. Internationally renowned experts present their current research followed by an open discussion. | |||||
Objective | Weekly seminar about cutting edge topics in immunology and infection biology. Internationally renowned experts present their current research followed by an open discussion. The aim of this course is to confront students with current research topics and with scientific presentation. The course offers the opportunity to gain in depth knowledge about diverse topics which are often only briefly touched in the concept courses and to engage in discussion with experts in the field. | |||||
Content | Immunology and infection biology. The specific topics are variable and depend each semester on the list of invited experts. | |||||
551-1104-00L | Selected Topics in Forest Mycology | W | 2 credits | 1V | I. L. Brunner, M. Peter Baltensweiler, D. H. Rigling | |
Abstract | Lifestyles and functions of symbiotic, saprobic and pathogenic fungi, communities of mycorrhizas and its functional aspects, evolution and phylogenetic aspects of plant-fungal interactions, inter- and intraspecific interactions of mycelia, role of fungi in nutrient mobilisation and weathering. | |||||
Objective | In-depth knowledge of the biology and ecology of fungi in the forest. Self-examination of the current literature. | |||||
Content | In-depth treatment of selected topics of fungi in the forest ecosystem: Lifestyles and functions of symbiotic, saprobic and pathogenic fungi, communities of mycorrhizas and its functional aspects, evolution and phylogenetic aspects of plant-fungal interactions, inter- and intraspecific interactions of mycelia, role of fungi in nutrient mobilisation and weathering. Basics will be presented in lectures. In addition, individual study of the learning matter with the help of current literature and presentations. | |||||
Lecture notes | Documents for the course will be handed out. | |||||
Literature | Smith S.E. and Read D.J. 1997. Mycorrhizal Symbiosis. Academic Press, 2nd ed., pp. 605. | |||||
551-0216-00L | Field Course in Mycology Number of participants limited to 8. | W | 3 credits | 3.5P | R. Berndt, M. A. Garcia Otalora | |
Abstract | This mycology class combines field excursions and a practical training in the lab. The participants will be introduced to the species diversity and morphology of basidio- and ascomycetes, learn how fungi are collected for scientific purposes and how they are determined by macroscopic and microscopic characters using specialist literature. This year’s course will focus on lichenized fungi. | |||||
Objective | Recognizing fungal species diversity and learning to determine basidio- and ascomycete species. Collecting, documenting and preparing herbarium specimens of fungi for scientific purposes. Introduction to the light microscopy of fungi. Learning how to use specialist mycology literature and understanding the technical terminology. Knowledge of the relevant macroscopic und microscopic characters of fungi. | |||||
Content | Introduction to the taxonomy of basidio- and ascomycetes. Field excursions to study fungi in their habitats. Study and determination of the collections in the lab. Micromorphology of basidio- and ascomycetes (incl. lichenized fungi). Introduction to major groups of plant-pathogenic fungi, especially rust fungi. | |||||
Lecture notes | Scripts will be handed out. | |||||
Literature | Technical literature will be provided in the lecture room. | |||||
Prerequisites / Notice | The course is restricted to eight persons who are requested to enroll by a written application to the lecturers. Requirements: The participants need to read in advance selected chapters from mycology textbooks (to be announced) to gather the basic mycology knowledge necessary for the course. | |||||
551-1132-00L | Basic Virology | W | 2 credits | 1V | K. Tobler, C. Fraefel | |
Abstract | Introduction into the basics of virology, including characterization of viruses, virus-cell interactions, virus-host interactions, virus-host population interactions, basics of prevention and prophylaxis as well as diagnostics. | |||||
Objective | Introduction into the basics of virology. | |||||
Content | Basics in virology. Characterization of viruses, virus-cell interactions, virus-host interactions, virus-host population interactions, basics of prevention and prophylaxis as well as diagnostics. | |||||
Lecture notes | The lecture uses the lecturer's 'Allgemeine Virologie' as a basis. The lecturer's slides as well as selected primary literature will be provided 24-48 hrs prior to the lecture in pdf format. | |||||
Literature | Flint et al., 2009. Principles of Virology, 3rd Edition. ASM Press, Washington, DC, USA. Vol I. ISBN 978-1-55581-479-3 Vol II. ISBN 978-1-55581-480-9 | |||||
Prerequisites / Notice | Basic knowledge in molecular biology, cell biology, immunology. | |||||
551-0140-00L | Epigenetics | W | 4 credits | 2V | A. Wutz, U. Grossniklaus, R. Paro, R. Santoro | |
Abstract | Epigenetics studies the inheritance of traits that cannot be attributed to changes in the DNA sequence. The lecture will present an overview of different epigenetic phenomena and provide detailed insight into the underlying molecular mechanisms. The role of epigenetic processes in the development of cancer and other disorders will be discussed. | |||||
Objective | The aim of the course is to gain an understanding of epigenetic mechanisms and their impact on the development of organisms, regenerative processes or manifestation of disease. | |||||
Content | Topics - historical overview, concepts and comparison Genetics vs. Epigenetics - Biology of chromatin: structure and function, organization in the nucleus and the role of histone modifications in processes like transcription and replication - DNA methylation as an epigenetic modification - Inheritance of epigenetic modifications during cell division: cellular memory - Stability and reversibility of epigenetic modifications: cellular plasticity and stem cells - Genomic imprinting in plants and mammals - X chromosome inactivation and dosis compensation - position effects, paramutations and transvection - RNA-induced gene silencing - The role of epigenetic processes in cancer development or cell aging | |||||
751-4904-00L | Microbial Pest Control | W | 2 credits | 2G | J. Enkerli, G. Grabenweger | |
Abstract | This lecture provides conceptual as well as biological and ecological background on microbial pest management. Methods and techniques applied to develop and monitor microbial control agents are elucidated. | |||||
Objective | To know the most important groups of insect pathogens and their characteristics. To become familiar with the basic steps necessary for the development of microbial control agents. To understand the techniques and methods used to monitor field applications and the procedures involved in registration of products for microbial pest management. | |||||
Content | Definitions and general terms used in microbial control are presented. Biological and ecological aspects of all arthropod-pathogenic groups (virus, bacteria, fungi and nematodes) as well as their advantages and disadvantages in relation to biocontrol are discussed. Particular emphasis is put on hypocrealean and entomophthoralean fungi. Examples are used to demonstrate how projects in microbial control can be set up, how pathogens can be applied and how efficacy, non-target effects, persistence and dissemination are monitored. Furthermore, the necessary steps for product development, commercial aspects and registration requirements are discussed. | |||||
Lecture notes | Lecture notes comprising the basic aspects will be provided. | |||||
Literature | Additional literature will be indicated in the lecture |
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