Suchergebnis: Katalogdaten im Herbstsemester 2014

Biomedical Engineering Master Information
Master-Studium gemäss Studienreglement 2013
Vertiefungsfächer
Bioimaging
Wahlfächer der Vertiefung
Diese Fächer sind für die Vertiefung in Bioimaging besonders empfohlen. Bei abweichender Fächerwahl konsultieren Sie bitte den Track Adviser.
NummerTitelTypECTSUmfangDozierende
465-0953-00LBiostatistikW2 KP2V + 1UB. Sick
KurzbeschreibungDer Kurs behandelt einfache quantitative und graphische als auch komplexere Methoden der Biostatistik. Inhalt: Deskriptive Statistik, Wahrscheinlichkeitsrechnung und Versuchsplanung, Prüfung von Hypothesen, Konfidenzintervalle, Korrelation, einfache und multiple lineare Regression, Varianzanalyse, logistische Regression, Survivalanalyse (Kaplan-Meier Kurven und Cox-Regression).
Lernziel
551-1295-00LIntroduction to Bioinformatics: Concepts and Applications Information W6 KP4GW. Gruissem, K. Bärenfaller, A. Caflisch, G. Capitani, J. Fütterer, M. Robinson, A. Wagner
KurzbeschreibungSpeicherung, Verarbeitung und Analyse grosser Datenmengen sind in vielen Forschungsbereichen der modernen Biologie essentiell geworden. Die Vorlesung gibt eine grundlegende Einführung in Anwendungsbereiche von Bioinformatik in der Biologie und stellt einige leicht zugängliche Programme und Datenbanken für den Anwender in Theorie und Praxis vor.
LernzielIntroduction to Bioinformatics I: Concepts and Applications (formerly Bioinformatics I) will provide students with the theoretical background of approaches to store and retrieve information from large databases. Concepts will be developed how DNA sequence information can be used to understand phylogentic relationships, how RNA sequence relates to structure, and how protein sequence information can be used for genome annotation and to predict protein folding and structure. Students will be introduced to quantitative methods for measuring gene expression and how this information can be used to model gene networks. Methods will be discussed to construct protein interaction maps and how this information can be used to simulate dynamic molecular networks.

In addition to the theoretical background, the students will develop hands-on experiences with the bioinformatics methods through guided exercises. The course provides students from different backgrounds with basic training in bioinformatics approaches that have impact on biological, chemical and physics experimentation. Bioinformatics approaches draw significant expertise from mathematics, statistics and computational science.

Although "Intoduction to Bioinformatics I" will focus on theory and praxis of bioinformatics approaches, the course provides an important foundation for the course "Introduction to Bioinformatics II: Fundamentals of computer science, modeling and algorithms" that will be offered in the following semester.
InhaltBioinformatics I will cover the following topics:

From genes to databases and information
BLAST searches
Prediction of gene function and regulation
RNA structure prediction
Gene expression analysis using microarrays
Protein sequence and structure databases
WWW for bioinformatics
Protein sequence comparisons
Proteomics and de novo protein sequencing
Protein structure prediction
Cellular and protein interaction networks
Molecular dynamics simulation
Biologiefächer
NummerTitelTypECTSUmfangDozierende
227-0945-00LCell and Molecular Biology for EngineersO6 KP4GC. Frei
KurzbeschreibungThe course gives an introduction into cellular and molecular biology, specifically for students with a background in engineering. The focus will be on the basic organization of eukaryotic cells, molecular mechanisms and cellular functions. Textbook knowledge will be combined with results from recent research and technological innovations in biology.
LernzielAfter completing this course, engineering students will be able to apply their previous training in the quantitative and physical sciences to modern biology. Students will also learn the principles how biological models are established, and how these models can be tested.
InhaltLectures will include the following topics: DNA, chromosomes, RNA, protein, genetics, gene expression, membrane structure and function, vesicular traffic, cellular communication, energy conversion, cytoskeleton, cell cycle, cellular growth, apoptosis, autophagy, cancer, development and stem cells.

In addition, three journal clubs will be held, where one/two publictions will be discussed. For each journal club, students (alone or in groups of up to three students) have to write a summary and discussion of the publication. These written documents will be graded, and count as 25% for the final grade.
SkriptScripts of all lectures will be available.
Literatur"Molecular Biology of the Cell" (5th edition) by Alberts, Johnson, Lewis, Raff, Roberts, and Walter.
Biomechanics
Kernfächer der Vertiefung
Während des Studiums müssen mindestens 12 KP aus Kernfächern einer Vertiefung (Track) erreicht werden.
NummerTitelTypECTSUmfangDozierende
227-0385-00LBiomedical Imaging Information W4 KP3GS. Kozerke, U. Moser, M. Rudin
KurzbeschreibungIntroduction and analysis of medical imaging technology including X-ray procedures, computed tomography, nuclear imaging techniques using single photon and positron emission tomography, magnetic resonance imaging and ultrasound imaging techniques.
LernzielUnderstand the physical and technical principles underlying X-ray imaging, computed tomography, single photon and positron emission tomography, magnetic resonance imaging, ultrasound and Doppler imaging techniques. Develop the mathematical framework to describe image encoding/decoding, point-spread function/modular transfer function, signal-to-noise ratio, contrast behavior for each of the methods.
InhaltX-ray imaging
Computed tomography
Single photon emission tomography
Positron emission tomography
Magnetic resonance imaging
Ultrasound/Doppler imaging
SkriptLecture notes and handouts: Biomedical Imaging
LiteraturIntroduction to Medical Imaging: Physics, Engineering and Clinical Applications by Andrew Webb, Nadine Barrie Smith,
Cambridge University Press
227-0386-00LBiomedical Engineering Information W4 KP3GJ. Vörös, S. J. Ferguson, S. Kozerke, U. Moser, M. Rudin, M. P. Wolf, M. Zenobi-Wong
KurzbeschreibungIntroduction into selected topics of biomedical engineering as well as their relationship with physics and physiology. The focus is on learning the concepts that govern common medical instruments and the most important organs from an engineering point of view. In addition, the most recent achievements and trends of the field of biomedical engineering are also outlined.
LernzielIntroduction into selected topics of biomedical engineering as well as their relationship with physics and physiology. The course provides an overview of the various topics of the different tracks of the biomedical engineering master course and helps orienting the students in selecting their specialized classes and project locations.
InhaltIntroduction into neuro- and electrophysiology. Functional analysis of peripheral nerves, muscles, sensory organs and the central nervous system. Electrograms, evoked potentials. Audiometry, optometry. Functional electrostimulation: Cardiac pacemakers. Function of the heart and the circulatory system, transport and exchange of substances in the human body, pharmacokinetics. Endoscopy, medical television technology. Lithotripsy. Electrical Safety. Orthopaedic biomechanics. Lung function. Bioinformatics and Bioelectronics. Biomaterials. Biosensors. Microcirculation.Metabolism.
Practical and theoretical exercises in small groups in the laboratory.
SkriptIntroduction to Biomedical Engineering
by Enderle, Banchard, and Bronzino

AND

Link
227-0447-00LImage Analysis and Computer Vision Information W6 KP3V + 1UG. Székely, O. Göksel, L. Van Gool
KurzbeschreibungLight and perception. Digital image formation. Image enhancement and feature extraction. Unitary transformations. Color and texture. Image segmentation and deformable shape matching. Motion extraction and tracking. 3D data extraction. Invariant features. Specific object recognition and object class recognition.
LernzielOverview of the most important concepts of image formation, perception and analysis, and Computer Vision. Gaining own experience through practical computer and programming exercises.
InhaltThe first part of the course starts off from an overview of existing and emerging applications that need computer vision. It shows that the realm of image processing is no longer restricted to the factory floor, but is entering several fields of our daily life. First it is investigated how the parameters of the electromagnetic waves are related to our perception. Also the interaction of light with matter is considered. The most important hardware components of technical vision systems, such as cameras, optical devices and illumination sources are discussed. The course then turns to the steps that are necessary to arrive at the discrete images that serve as input to algorithms. The next part describes necessary preprocessing steps of image analysis, that enhance image quality and/or detect specific features. Linear and non-linear filters are introduced for that purpose. The course will continue by analyzing procedures allowing to extract additional types of basic information from multiple images, with motion and depth as two important examples. The estimation of image velocities (optical flow) will get due attention and methods for object tracking will be presented. Several techniques are discussed to extract three-dimensional information about objects and scenes. Finally, approaches for the recognition of specific objects as well as object classes will be discussed and analyzed.
SkriptCourse material Script, computer demonstrations, exercises and problem solutions
Voraussetzungen / BesonderesPrerequisites:
Basic concepts of mathematical analysis and linear algebra. The computer exercises are based on Linux and C.
The course language is English.
227-0965-00LMicro and Nano-Tomography of Biological TissuesW4 KP3GM. Stampanoni, K. S. Mader
KurzbeschreibungEinführung in die physikalischen und technischen Grundkenntnisse der tomographischen Röntgenmikroskopie. Verschiedene Röntgenbasierten-Abbildungsmechanismen (Absorptions-, Phasen- und Dunkelfeld-Kontrast) werden erklärt und deren Einsatz in der aktuellen Forschung vorgestellt, insbesondere in der Biologie. Die quantitative Auswertung tomographische Datensätzen wird ausführlich beigebracht.
LernzielEinführung in die Grundlagen der Röntgentomographie auf der Mikrometer- und Nanometerskala, sowie in die entsprechenden Bildbearbeitungs- und Quantifizierungsmethoden, unter besonderer Berücksichtigung von biologischen Anwendungen.
InhaltSynchrotron basierte Röntgenmikro- und Nanotomographie ist heutzutage eine leistungsfähige Technik für die hochaufgelösten zerstörungsfreien Untersuchungen einer Vielfalt von Materialien. Die aussergewöhnlichen Stärke und Kohärenz der Strahlung einer Synchrotronquelle der dritten Generation erlauben quantitative drei-dimensionale Aufnahmen auf der Mikro- und Nanometerskala und erweitern die klassischen Absorption-basierten Verfahrensweisen auf die kontrastreicheren kantenverstärkten und phasenempfindlichen Methoden, die für die Analyse von biologischen Proben besonders geeignet sind.

Die Vorlesung umfasst eine allgemeine Einführung in die Grundsätze der Röntgentomographie, von der Bildentstehung bis zur 3D Bildrekonstruktion. Sie liefert die physikalischen und technischen Grundkentnisse über die bildgebenden Synchrotronstrahllinien, vertieft die neusten Phasenkontrastmethoden und beschreibt die ersten Anwendungen nanotomographischer Röntgenuntersuchungen.

Schliesslich liefert der Kurs den notwendigen Hintergrund, um die quantitative Auswertung tomographischer Daten zu verstehen, von der grundlegenden Bildanalyse bis zur komplexen morphometrischen Berechnung und zur 3D-Visualisierung, unter besonderer Berücksichtigung von biomedizinischen Anwendungen.
SkriptOnline verfügbar
LiteraturWird in der Vorlesung angegeben.
376-1651-00LClinical and Movement BiomechanicsW4 KP3GS. Lorenzetti, R. List, N. Singh
KurzbeschreibungMeasurement and modeling of the human movement during daily activities and in a clinical environment.
LernzielThe students are able to analyse the human movement from a technical point of view, to process the data and perform modeling with a focus towards clinical application.
InhaltThis course includes ethical considerations, measurement techniques, clinical testing, accessing movement data and anysis as well as modeling with regards to human movement.
376-1985-00LTrauma-BiomechanikW4 KP2V + 1UK.‑U. Schmitt, M. H. Muser
KurzbeschreibungTrauma-Biomechanik ist ein interdiszipliäres Fach, das sich mit der Biomechanik von Verletzungen sowie Möglichkeiten zur Prävention von Verletzungen beschäftigt. Die Vorlesung stellt die Grundlagen der Trauma-Biomechanik dar.
LernzielVermittlung von Grundlagen der Trauma-Biomechanik.
InhaltDie Vorlesung beschäftigt sich mit Verletzungen des menschlichen Körpers und den zugrunde liegenden Verletzungsmechanismen. Hierbei bilden Verletzungen, die im Strassenverkehr erlitten werden, den Schwerpunkt. Weitere Vorlesungsthemen sind: Crash-Tests und die dazugehörige Messtechnik (z. B. Dummys), sowie aktuelle Themen der Trauma-Biomechanik wie z.B. Fussgänger-Kollisionen, Kinderrückhaltesysteme und Fahrzeugsitze.
SkriptUnterlagen können via Homepage bezogen werden.
LiteraturSchmitt K-U, Niederer P, M. Muser, Walz F: "Trauma Biomechanics - An Introduction to Injury Biomechanics" bzw. "Trauma-Biomechanik - Einführung in die Biomechanik von Verletzungen", beide Springer Verlag.
Wahlfächer der Vertiefung
Diese Fächer sind für die Vertiefung in Biomechanics besonders empfohlen. Bei abweichender Fächerwahl konsultieren Sie bitte den Track Adviser.
NummerTitelTypECTSUmfangDozierende
151-0255-00LEnergy Conversion and Transport in Biosystems
Findet dieses Semester nicht statt.
W4 KP2V + 1UD. Poulikakos, A. Ferrari
KurzbeschreibungGrundlagen und Anwendungen von Thermodynamik, Energieumwandlung und Fluiddynamik in Biosystemen und Biomedizin auf Makro- und Zellebene.
LernzielGrundlagen und Anwendungen von Thermodynamik (Wärmeübertragung) Energieumwandlung und Fluiddynamik in Biosystemen und Biomedizin. Diese Grundlagen werden auf der Makro- als auch der Mikroebene (Zellebene) untersucht. Die Vorlesung vermittelt das für die Analysierung solcher Probleme nötige Wissen.
InhaltModellierung von Wärmeübergang und Stofftransport (thermische Energie, chemisch gebundene Energie) im menschlichen Körper. Physiologie, Pathologie und biomedizinische Eingriffe mittels extremer Temperaturen (medizinische Radiofrequenztherapie, Einfrieren von Gewebe und Tieftemperaturbehandlungen) . Einführung in die wichtigsten Flüssigkeitssysteme des menschlichen Körpers (Herz-Kreislauf, Hirn-Rückenmarksflüssigkeit usw.). Beschreibung der Funktionalität dieser Systeme mittels analytischer, experimenteller und numerischer Methoden, um ihre Eigenheiten zu erfassen. Einführung in biomedizinische Methoden zur Behandlung von Erkrankungen dieser Flüssigkeitssysteme.
Einführung in den Zellstoffwechsel, Energietransport in Zellen und Zell-Thermodynamik.
SkriptSkript und weitere Literatur wird verteilt.
LiteraturIm Skript gegeben.
151-0511-00LMechanics of Nano- and Micro-MaterialsW4 KP2V + 1UC. Daraio
KurzbeschreibungThe course provides an introduction to the mechanics of nano- and micro-materials and devices, in the quasistatic and dynamic domains. It reviews scale effects in materials, surveys available characterization techniques and describes the effects of surfaces and microscale contacts. Recent applications of nano- and micro-materials in engineering systems will be discussed.
LernzielLearn the fundamental mechanical properties of nano- and micro-system. Understand the effects of scales on the response of materials. Explore applications and devices exploiting the response of materials at small scales.
Inhaltfollows soon
SkriptSlides and notes from the course will be provided.
LiteraturRelevant articles and reading materials will be provided. Various books will be recommended pertaining to the topics covered.
Voraussetzungen / BesonderesMechanics I, II, III
151-0524-00LContinuum Mechanics for EngineersW4 KP2V + 1UE. Mazza
KurzbeschreibungKonstitutive Gleichungen für strukturmechanische Berechnungen werden behandelt. Dies beinhaltet anisotrope lineare Elastizität, lineare Viskoelastizität, Plastizität und Viscoplastizität. Es werden die Grundlagen der Mikro-Makro Modellierung und der Laminattheorie eingeführt. Die theoretischen Ausführungen werden durch Beispiele aus Ingenieuranwendungen und Experimente ergänzt.
LernzielBehandlung von Grundlagen zur Lösung kontinuumsmechanischer Probleme der Anwendung, mit besonderem Fokus auf konstitutive Gesetze.
InhaltAnisotrope Elastizität, Linearelastisches und linearviskoses Stoffverhalten, Viskoelastizität, mikro-makro Modellierung, Laminattheorie, Plastizität, Viscoplastizität, Beispiele aus der Ingenieuranwendung, Vergleich mit Experimenten.
Skriptja
151-0604-00LMicrorobotics Information W4 KP3GB. Nelson
KurzbeschreibungMicrorobotics is an interdisciplinary field that combines aspects of robotics, micro and nanotechnology, biomedical engineering, and materials science. The aim of this course is to expose students to the fundamentals of this emerging field. Throughout the course students are expected to submit assignments. The course concludes with an end-of-semester examination.
LernzielThe objective of this course is to expose students to the fundamental aspects of the emerging field of microrobotics. This includes a focus on physical laws that predominate at the microscale, technologies for fabricating small devices, bio-inspired design, and applications of the field.
InhaltMain topics of the course include:
- Scaling laws at micro/nano scales
- Electrostatics
- Electromagnetism
- Low Reynolds number flows
- Observation tools
- Materials and fabrication methods
- Applications of biomedical microrobots
SkriptThe powerpoint slides presented in the lectures will be made available in hardcopy and as pdf files. Several readings will also be made available electronically.
Voraussetzungen / BesonderesThe lecture will be taught in English.
151-0605-00LNanosystemsW4 KP4GA. Stemmer
KurzbeschreibungFrom atoms to molecules to condensed matter: characteristic properties of simple nanosystems and how they evolve when moving towards complex ensembles.
Intermolecular forces, their macroscopic manifestations, and ways to control such interactions.
Self-assembly and directed assembly of 2D and 3D structures.
Special emphasis on the emerging field of molecular electronic devices.
LernzielFamiliarize students with basic science and engineering principles governing the nano domain.
InhaltThe course addresses basic science and engineering principles ruling the nano domain. We particularly work out the links between topics that are traditionally taught separately.

Special emphasis is placed on the emerging field of molecular electronic devices, their working principles, applications, and how they may be assembled.

Topics are treated in 2 blocks:

(I) From Quantum to Continuum
From atoms to molecules to condensed matter: characteristic properties of simple nanosystems and how they evolve when moving towards complex ensembles.

(II) Interaction Forces on the Micro and Nano Scale
Intermolecular forces, their macroscopic manifestations, and ways to control such interactions.
Self-assembly and directed assembly of 2D and 3D structures.
Literatur- Kuhn, Hans; Försterling, H.D.: Principles of Physical Chemistry. Understanding Molecules, Molecular Assemblies, Supramolecular Machines. 1999, Wiley, ISBN: 0-471-95902-2
- Chen, Gang: Nanoscale Energy Transport and Conversion. 2005, Oxford University Press, ISBN: 978-0-19-515942-4
- Ouisse, Thierry: Electron Transport in Nanostructures and Mesoscopic Devices. 2008, Wiley, ISBN: 978-1-84821-050-9
- Wolf, Edward L.: Nanophysics and Nanotechnology. 2004, Wiley-VCH, ISBN: 3-527-40407-4

- Israelachvili, Jacob N.: Intermolecular and Surface Forces. 2nd ed., 1992, Academic Press,ISBN: 0-12-375181-0
- Evans, D.F.; Wennerstrom, H.: The Colloidal Domain. Where Physics, Chemistry, Biology, and Technology Meet. Advances in Interfacial Engineering Series. 2nd ed., 1999, Wiley, ISBN: 0-471-24247-0
- Hunter, Robert J.: Foundations of Colloid Science. 2nd ed., 2001, Oxford, ISBN: 0-19-850502-7
Voraussetzungen / BesonderesCourse format:

Lectures: Thursday 10-12, ML F 36

Homework: Mini-Reviews
Students select a paper (list distributed in class) and expand the topic into a Mini-Review that illuminates the particular field beyond the immediate results reported in the paper.
227-2037-00LPhysical Modelling and Simulation Information W5 KP4GC. Hafner, J. Smajic
KurzbeschreibungPhysical modelling plays an important role in the analysis and design of new structures, especially for micro and nano devices where fabrication and measurement are difficult. After the fundamentals of electromagnetics, mechanics, and thermodynamics, an introduction to the main concepts and most widely used codes for physical modelling is given and commercial codes are applied.
LernzielBasic knowledge of the fundamental equations and effects of electromagnetics, mechanics, and thermodynamics. Knowledge of the main concepts of numerical methods for physical modelling and simulation. Ability 1) to select appropriate software, 2) to apply it for solving given problems, 3) to validate the results, 4) to interactively improve the models until sufficiently accurate results are obtained.
InhaltSince the fabrication and characterization of micro- and nanostructures is difficult, expensive, and time-consuming, numerical modelling drastically reduced the design process. Although many commercial software packages are available, it is important to know the drawbacks and difficulties of the numerical methods behind them and to be able to validate the results obtained with such packages.
First, an introduction to the fundamental equations and effects of electromagnetics, mechanics, and thermodynamics is given. This is important for understanding the problems to be analyzed and for validating results obtained from software packages. After this, the main concepts of numerical methods and of the most widely used codes for physical modelling are outlined and compared, which is essential for the adequate selection of software for solving given problems. After this, prominent commercial software packages are applied to various types of problems, ranging from electrodynamics to multiphysics. For becoming able to select appropriate software and to validate the results obtained, different commercial software packages will be used and compared during the exercises in form of small projects.
263-5001-00LIntroduction to Finite Elements and Sparse Linear System Solving Information W4 KP2V + 1UP. Arbenz, T. Kaman
KurzbeschreibungThe finite element (FE) method is the method of choice for (approximately) solving partial differential equations on complicated domains. In the first third of the lecture, we give an introduction to the method. The rest of the lecture will be devoted to methods for solving the large sparse linear systems of equation that a typical for the FE method. We will consider direct and iterative methods.
LernzielStudents will know the most important direct and iterative solvers for sparse linear systems. They will be able to determine which solver to choose in particular situations.
InhaltI. THE FINITE ELEMENT METHOD

(1) Introduction, model problems.

(2) 1D problems. Piecewise polynomials in 1D.

(3) 2D problems. Triangulations. Piecewise polynomials in 2D.

(4) Variational formulations. Galerkin finite element method.

(5) Implementation aspects.


II. DIRECT SOLUTION METHODS

(6) LU and Cholesky decomposition.

(7) Sparse matrices.

(8) Fill-reducing orderings.


III. ITERATIVE SOLUTION METHODS

(9) Stationary iterative methods, preconditioning.

(10) Preconditioned conjugate gradient method (PCG).

(11) Incomplete factorization preconditioning.

(12) Multigrid preconditioning.

(13) Nonsymmetric problems (GMRES, BiCGstab).

(14) Indefinite problems (SYMMLQ, MINRES).
Literatur[1] M. G. Larson, F. Bengzon: The Finite Element Method: Theory, Implementation, and Applications. Springer, Heidelberg, 2013.

[2] H. Elman, D. Sylvester, A. Wathen: Finite elements and fast iterative solvers. OUP, Oxford, 2005.

[3] Y. Saad: Iterative methods for sparse linear systems (2nd ed.). SIAM, Philadelphia, 2003.

[4] T. Davis: Direct Methods for Sparse Linear Systems. SIAM, Philadelphia, 2006.

[5] H.R. Schwarz: Die Methode der finiten Elemente (3rd ed.). Teubner, Stuttgart, 1991.
Voraussetzungen / BesonderesPrerequisites: Linear Algebra, Analysis, Computational Science.
The exercises are made with Matlab.
376-1219-00LRehabilitation Engineering II: Rehabilitation of Sensory and Vegetative Functions Information W3 KP2VR. Riener, R. Gassert
KurzbeschreibungRehab. Engineering is the application of science and technology to ameliorate the handicaps of individuals with disabilities to reintegrate them into society.The goal is to present classical and new rehabilitation engineering principles applied to compensate or enhance motor, sensory, and cognitive deficits. Focus is on the restoration and treatment of the human sensory and vegetative system.
LernzielProvide knowledge on the anatomy and physiology of the human sensory system, related dysfunctions and pathologies, and how rehabilitation engineering can provide sensory restoration and substitution.
InhaltIntroduction, problem definition, overview
Rehabilitation of visual function
- Anatomy and physiology of the visual sense
- Technical aids (glasses, sensor substitution)
- Retina and cortex implants
Rehabilitation of hearing function
- Anatomy and physiology of the auditory sense
- Hearing aids
- Cochlea Implants
Rehabilitation and use of kinesthetic and tactile function
- Anatomy and physiology of the kinesthetic and tactile sense
- Tactile/haptic displays for motion therapy (incl. electrical stimulation)
- Role of displays in motor learning
Rehabilitation of vestibular function
- Anatomy and physiology of the vestibular sense
- Rehabilitation strategies and devices (e.g. BrainPort)
Rehabilitation of vegetative Functions
- Cardiac Pacemaker
- Phrenic stimulation, artificial breathing aids
- Bladder stimulation, artificial sphincter
Brain stimulation and recording
- Deep brain stimulation for patients with Parkinson, epilepsy, depression
- Brain-Computer Interfaces
LiteraturIntroductory Books:

An Introduction to Rehabilitation Engineering. R. A. Cooper, H. Ohnabe, D. A. Hobson (Eds.). Taylor & Francis, 2007.

Principles of Neural Science. E. R. Kandel, J. H. Schwartz, T. M Jessell (Eds.). Mc Graw Hill, New York, 2000.

Force and Touch Feedback for Virtual Reality. G. C. Burdea (Ed.). Wiley, New York, 1996 (available on NEBIS).

Human Haptic Perception, Basics and Applications. M. Grunwald (Ed.). Birkhäuser, Basel, 2008.

The Sense of Touch and Its Rendering, Springer Tracts in Advanced Robotics 45, A. Bicchi et al.(Eds). Springer-Verlag Berlin, 2008.

Interaktive und autonome Systeme der Medizintechnik - Funktionswiederherstellung und Organersatz. Herausgeber: J. Werner, Oldenbourg Wissenschaftsverlag 2005.

Neural prostheses - replacing motor function after desease or disability. Eds.: R. Stein, H. Peckham, D. Popovic. New York and Oxford: Oxford University Press.

Advances in Rehabilitation Robotics - Human-Friendly Technologies on Movement Assistance and Restoration for People with Disabilities. Eds: Z.Z. Bien, D. Stefanov (Lecture Notes in Control and Information Science, No. 306). Springer Verlag Berlin 2004.

Intelligent Systems and Technologies in Rehabilitation Engineering. Eds: H.N.L. Teodorescu, L.C. Jain (International Series on Computational Intelligence). CRC Press Boca Raton, 2001.


Selected Journal Articles and Web Links:

Abbas, J., Riener, R. (2001) Using mathematical models and advanced control systems techniques to enhance neuroprosthesis function. Neuromodulation 4, pp. 187-195.

Bach-y-Rita P., Tyler M., and Kaczmarek K (2003). Seeing with the brain. International journal of human-computer-interaction, 15(2):285-295.

Burdea, G., Popescu, V., Hentz, V., and Colbert, K. (2000): Virtual reality-based orthopedic telerehabilitation, IEEE Trans. Rehab. Eng., 8, pp. 430-432
Colombo, G., Jörg, M., Schreier, R., Dietz, V. (2000) Treadmill training of paraplegic patients using a robotic orthosis. Journal of Rehabilitation Research and Development, vol. 37, pp. 693-700.

Hayward, V. (2008): A Brief Taxonomy of Tactile Illusions and
Demonstrations That Can Be Done In a Hardware Store. Brain Research Bulletin, Vol 75, No 6, pp 742-752

Krebs, H.I., Hogan, N., Aisen, M.L., Volpe, B.T. (1998): Robot-aided neurorehabilitation, IEEE Trans. Rehab. Eng., 6, pp. 75-87

Levesque. V. (2005). Blindness, technology and haptics. Technical report, McGill University. Available at: Link

Quintern, J. (1998) Application of functional electrical stimulation in paraplegic patients. NeuroRehabilitation 10, pp. 205-250.

Riener, R., Nef, T., Colombo, G. (2005) Robot-aided neurorehabilitation for the upper extremities. Medical & Biological Engineering & Computing 43(1), pp. 2-10.

Riener, R. (1999) Model-based development of neuroprostheses for paraplegic patients. Royal Philosophical Transactions: Biological Sciences 354, pp. 877-894.

The vOICe. Link.

VideoTact, ForeThought Development, LLC. Link
Voraussetzungen / BesonderesTarget Group:
Students of higher semesters and PhD students of
- D-MAVT, D-ITET, D-INFK, D-HEST
- Biomedical Engineering, Robotics, Systems and Control
- Medical Faculty, University of Zurich
Students of other departments, faculties, courses are also welcome
376-1279-00LVirtual Reality in Medicine Belegung eingeschränkt - Details anzeigen
Findet dieses Semester nicht statt.
W3 KP2VR. Riener
KurzbeschreibungVirtual Reality has the potential to support medical training and therapy. This lecture will derive the technical principles of multi-modal (audiovisual, haptic, tactile etc.) input devices, displays and rendering techniques. Examples are presented in the fields of surgical training, intra-operative augmentation, and rehabilitation. The lecture is accompanied by practical courses and excursions.
LernzielProvide theoretical and practical knowledge of new principles and applications of multi-modal simulation and interface technologies in medical education, therapy, and rehabilitation.
InhaltVirtual Reality has the potential to provide descriptive and practical information for medical training and therapy while relieving the patient and/or the physician. Multi-modal interactions between the user and the virtual environment facilitate the generation of high-fidelity sensory impressions, by using not only visual and auditory modalities, but also kinesthetic, tactile, and even olfactory feedback. On the basis of the existing physiological constraints, this lecture will derive the technical requirements and principles of multi-modal input devices, displays, and rendering techniques. Several examples are presented that are currently being developed or already applied for surgical training, intra-operative augmentation, and rehabilitation. The lecture will be accompanied by several practical courses on graphical and haptic display devices as well as excursions to facilities equipped with large-scale VR equipment.

Target Group:
Students of higher semesters and PhD students of
- D-HEST, D-MAVT, D-ITET, D-INFK, D-PHYS
- Robotics, Systems and Control Master
- Biomedical Engineering/Movement Science and Sport
- Medical Faculty, University of Zurich
Students of other departments, faculties, courses are also welcome!
LiteraturBook: Virtual Reality in Medicine. Riener, Robert; Harders, Matthias; 2012 Springer.
Voraussetzungen / BesonderesThe course language is English.
Basic experience in Information Technology and Computer Science will be of advantage
More details will be announced in the lecture.
376-1714-00LBiocompatible MaterialsW4 KP3GK. Maniura, P. M. Kollmannsberger, J. Möller, M. Zenobi-Wong
KurzbeschreibungIntroduction to molecules used for biomaterials, molecular interactions between different materials and biological systems (molecules, cells, tissues). The concept of biocompatibility is discussed and important techniques from biomaterials research and development are introduced.
LernzielThe class consists of three parts:
1. Introdcution into molecular characteristics of molecules involved in the materials-to-biology interface. Molecular design of biomaterials.
2. The concept of biocompatibility.
3. Introduction into methodology used in biomaterials research and application.
InhaltIntroduction into native and polymeric biomaterials used for medical applications. The concepts of biocompatibility, biodegradation and the consequences of degradation products are discussed on the molecular level. Different classes of materials with respect to potential applications in tissue engineering and drug delivery are introduced. Strong focus lies on the molecular interactions between materials having very different bulk and/or surface chemistry with living cells, tissues and organs. In particular the interface between the materials surfaces and the eukaryotic cell surface and possible reactions of the cells with an implant material are elucidated. Techniques to design, produce and characterize materials in vitro as well as in vivo analysis of implanted and explanted materials are discussed.
In addition, a link between academic research and industrial entrepreneurship is established by external guest speakers.
SkriptHandouts can be accessed online.
LiteraturLiteratur
Biomaterials Science: An Introduction to Materials in Medicine, Ratner B.D. et al, 3rd Edition, 2013
Comprehensive Biomaterials, Ducheyne P. et al., 1st Edition, 2011

(available online via ETH library)

Handouts provided during the classes and references therin.
376-1351-00LMicro/Nanotechnology and Microfluidics for Biomedical ApplicationsW2 KP2VE. Delamarche
KurzbeschreibungThis course is an introduction to techniques in micro/nanotechnology and to microfluidics. It reviews how many familiar devices are built and can be used for research and biomedical applications. Transistors for DNA sequencing, beamers for patterning proteins, hard-disk technology for biosensing and scanning microfluidics for analyzing tissue sections are just a few examples of the covered topics.
LernzielThe main objective of the course is to introduce micro/nanotechnology and microfluidics to students having a background in the life sciences. The course should familiarize the students with the techniques used in micro/nanotechnology and show them how micro/nanotechnology pervades throughout life sciences. Microfluidics will be emphasized due to their increasing importance in research and medical applications. The second objective is to have life students less intimidated by micro/nanotechnology and make them able to link instruments and techniques to specific problems that they might have in their projects/studies. This will also help students getting access to the ETHZ/IBM Nanotech Center infrastructure if needed.
InhaltMostly formal lectures (2 × 45 min), with a 2 hour visit and introduction to cleanroom and micro/nanotechnology instruments, last 3 sessions would be dedicated to the presentation and evaluation of projects by students (3 students per team).
Voraussetzungen / BesonderesNanotech center and lab visit at IBM would be mandatory, as well as attending the student project presentations.
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