551-0307-00L  Biomolecular Structure and Mechanism I: Protein Structure and Function

Semester Autumn Semester 2015
Lecturers R. Glockshuber, K. Locher, E. Weber-Ban
Periodicity yearly course
Language of instruction English
Comment D-BIOL BSc students are obliged to take part I and part II (next semester) as a two-semester course

Abstract Biophysics of protein folding, membrane proteins and biophysics of membranes, enzymatic catalysis, catalytic RNA and RNAi, current topics in protein biophysics and structural biology.
Objective Understanding of structure-function relationships in proteins and in protein folding, detailed understanding of biophysics and physical methods as well as modern methods for protein purification and microanalytics.
Lecture notes Scripts on the individual topics can be found under http://www.mol.biol.ethz.ch/teaching.
Literature Basics:
- Creighton, T.E., Proteins, Freeman, (1993)
- Fersht, A., Enzyme, Structure and Mechanism in Protein Science (1999), Freeman.
- Berg, Tymoczko, Stryer: Biochemistry (5th edition), Freeman (2001).

Current topics: References will be given during the lectures.