Markus Aebi: Katalogdaten im Herbstsemester 2019 |  |
| Name | Herr Prof. em. Dr. Markus Aebi |
| Lehrgebiet | Mykologie |
| Adresse | Institut für Mikrobiologie ETH Zürich, HCI F 439 Vladimir-Prelog-Weg 1-5/10 8093 Zürich SWITZERLAND |
| markus.aebi@micro.biol.ethz.ch | |
| Departement | Biologie |
| Beziehung | Professor emeritus |
| Nummer | Titel | ECTS | Umfang | Dozierende | |
|---|---|---|---|---|---|
| 551-0105-00L | Grundlagen der Biologie IA | 5 KP | 5G | M. Aebi, E. Hafen, M. Peter | |
| Kurzbeschreibung | Die Vorlesung vermittelt eine Einführung in die Grundlagen der Molekular- und Zellbiologie und der Genetik. | ||||
| Lernziel | Einführung in die Gebiete der modernen Biologie und in grundlegende biologischer Konzepte. | ||||
| Inhalt | Die Lehrveranstaltung ist in verschiedene Kapitel gegliedert: 1. Grundzüge der Evolution 2. Chemie des Lebens: Wasser; Kohlenstoff und molekulare Diversität; Biomoleküle 3. Die Zelle: Aufbau,Membranen, Zellzyklus 4. Metabolismus: Zellatmung, Photosynthese, Gärung 5. Vererbung: Meiose und sexuelle Reproduktion, Mendel-Genetik, chromosomale Basis der Vererbung, molekulare Basis der Vererbung, vom Gen zum Protein, Regulation der Genexpression, das Genom und dessen Evolution | ||||
| Skript | Kein Skript. | ||||
| Literatur | Das Lehrbuch "Biology" (Campbell, Reece) (11th Edition) ist die Grundlage der Vorlesung. Der Aufbau der Vorlesung ist in weiten Teilen mit jenem des Lehrbuchs identisch. Es wird den Studierenden empfohlen, das in Englisch geschriebene Lehrbuch zu verwenden. | ||||
| Voraussetzungen / Besonderes | Einzelne Teile des Inhalts des Lehrbuchs müssen im Selbststudium erarbeitet werden. | ||||
| 551-0363-00L | Complex Carbohydrates - Biosynthesis, Structure & Function   Number of participants limited to minimum 2 and maximum 16. The enrolment is done by the D-BIOL study administration. | 6 KP | 7G | T. Keys, M. Aebi | |
| Kurzbeschreibung | In vitro & in vivo experiments will introduce current research on the biosynthesis, structure & function of protein-bound glycans in different pro- and eukaryotic microorganisms. | ||||
| Lernziel | Participants are familiar with the biosynthesis, structure and function of N-glycans in microorganisms and with the methods for their analysis. | ||||
| Inhalt | * Topics: biosynthesis of asparagine-linked glycans in pro- and eukaryotes; structure of glycans in different organisms; methods to analyse the structure of glycans; brief introduction to function of glycans * Introductory lectures * Seminar with presentation and discussion of recent publications * Experiments that exemplify the current research done in the group | ||||
| 551-1105-00L | Glycobiology | 4 KP | 2V | M. Aebi, T. Hennet | |
| Kurzbeschreibung | Structural principles, nomenclature and different classes of glycosylation. The different pathways of N- and O-linked protein glycosylation and glycolipid biosynthesis in prokaryotes and eukaryotes are discussed. Specific glycan binding proteins and their role in deciphering the glycan code are presented. The role of glycans in infectious diseases, antigen mimicry and autoimmunity are discussed. | ||||
| Lernziel | Detailed knowledge in 1) the different areas of prokaryotic and eukaryotic glycobiology, in particular in the biosynthesis of glycoproteins and glycolipids, 2) the cellular machinery required for these pathways, 3) the principles of carbohydrate/protein interaction, 4) the function of lectins, 5) the role of glycans in infectious disease. | ||||
| Inhalt | Structure and linkages; analytical approaches; N-linked protein glycosylation (ER, Golgi); glycan-assisted protein folding and quality control; O-linked protein glycosylation; glucosaminoglycans; glycolipids; prokaryotic glycosylation pathways; lectins; glycans and infectious disease | ||||
| Skript | handouts | ||||
| Literatur | Introduction to Glycobiology; M.E.Taylor, K.Drickamer, Oxford University Press, 2003 Essentials of Glycobiology (third edition); A.Varki et al. Cold Spring Harbor Laboratory Press, 2017 | ||||
| Voraussetzungen / Besonderes | The course will be in English. It will include the preparation of short essays (marked) about defined topics in Glycobiology. | ||||
| 551-1106-00L | Progress Reports in Microbiology and Immunology Students must sign up via secr.micro.biol.ethz.ch | 0 KP | 5S | J. Piel, M. Aebi, H.‑M. Fischer, W.‑D. Hardt, A. Oxenius, J. Vorholt-Zambelli | |
| Kurzbeschreibung | Presentation and discussion of current research results in the field of Microbiology and Infection Immunology | ||||
| Lernziel | Precise and transparent presentation of research findings in relation to the current literature, critical discussion of experimental data and their interpretation, development and presentation of future research aims | ||||
| 551-1109-00L | Seminars in Microbiology | 0 KP | 2K | M. Aebi, H.‑M. Fischer, W.‑D. Hardt, M. Künzler, J. Piel, S. Sunagawa, J. Vorholt-Zambelli | |
| Kurzbeschreibung | Seminars by invited speakers covering selected microbiology themes. | ||||
| Lernziel | Discussion of selected microbiology themes presented by invited speakers. | ||||