Christian Frei: Catalogue data in Spring Semester 2022 |
| Name | Dr. Christian Frei |
| Address | Inst. f. Biomedizinische Technik ETH Zürich, GLC F 12.2 Gloriastrasse 37/ 39 8092 Zürich SWITZERLAND |
| Telephone | +41 44 632 45 85 |
| frei@biomed.ee.ethz.ch | |
| Department | Information Technology and Electrical Engineering |
| Relationship | Lecturer |
| Number | Title | ECTS | Hours | Lecturers | |
|---|---|---|---|---|---|
| 227-0945-10L | Cell and Molecular Biology for Engineers II This course is part II of a two-semester course. Knowledge of part I is required. | 3 credits | 2G | C. Frei | |
| Abstract | The course gives an introduction into cellular and molecular biology, specifically for students with a background in engineering. The focus will be on the basic organization of eukaryotic cells, molecular mechanisms and cellular functions. Textbook knowledge will be combined with results from recent research and technological innovations in biology. | ||||
| Learning objective | After completing this course, engineering students will be able to apply their previous training in the quantitative and physical sciences to modern biology. Students will also learn the principles how biological models are established, and how these models can be tested. | ||||
| Content | Lectures will include the following topics (part I and II): DNA, chromosomes, genome engineering, RNA, proteins, genetics, synthetic biology, gene expression, membrane structure and function, vesicular traffic, cellular communication, energy conversion, cytoskeleton, cell cycle, cellular growth, apoptosis, autophagy, cancer and stem cells. In addition, 4 journal clubs will be held, where recent publications will be discussed (2 journal clubs in part I and 2 journal clubs in part II). For each journal club, students (alone or in groups of up to three students) have to write a summary and discussion of the publication. These written documents will be graded and count as 40% for the final grade. | ||||
| Lecture notes | Scripts of all lectures will be available. | ||||
| Literature | "Molecular Biology of the Cell" (6th edition) by Alberts, Johnson, Lewis, Morgan, Raff, Roberts, and Walter. | ||||
| 227-0949-10L | Biological Methods for Engineers (Advanced Lab)  Limited number of participants. Students of the MSc in Biomedical Engineering have priority. | 4 credits | 9P | C. Frei | |
| Abstract | The 2 week-long, full-time block course covers basic laboratory skills and safety, cell culture, protein analysis, RNA/DNA Isolation and RT-PCR. Each topic will be introduced, followed by practical work at the bench. | ||||
| Learning objective | The goal of this laboratory course is to give students practical exposure to basic techniques of cell and molecular biology. | ||||
| Content | The goal of this laboratory course is to give students practical exposure to basic techniques of cell and molecular biology. | ||||
| Prerequisites / Notice | Enrollment is limited and preference given to students in the Masters of Biomedical Engineering program. | ||||
| 752-0100-AAL | Biochemistry Enrolment ONLY for MSc students with a decree declaring this course unit as an additional admission requirement. Any other students (e.g. incoming exchange students, doctoral students) CANNOT enrol for this course unit. | 2 credits | 4R | C. Frei | |
| Abstract | Basic knowledge of enzymology, in particular the structure, kinetics and chemistry of enzyme-catalysed reaction in vitro and in vivo. Biochemistry of metabolism: Those completing the course are able to describe and understand fundamental cellular metabolic processes. | ||||
| Learning objective | In this self-study course, the students will gain solid biochemical knowledge about enzymology, membrane biochemistry, and central metabolism. | ||||
| Content | Program Introduction, basics, composition of cells, biochemical units, Structure and function of proteins Enzymes and enzyme kinetics Carbohydrates Lipids and biological membranes Cellular metabolism: Glycolysis, gluconeogenesis, pentose phosphate pathway, glycogen metabolism, citric acid cycle, electron transport and ATP synthesis | ||||
| Lecture notes | Principles of Biochemistry (5th Edition) 5th Edition by Laurence A. Moran (Author), Robert A Horton (Author), Gray Scrimgeour (Author), Marc Perry (Author) | ||||
| Literature | Principles of Biochemistry (5th Edition) 5th Edition by Laurence A. Moran (Author), Robert A Horton (Author), Gray Scrimgeour (Author), Marc Perry (Author) | ||||
| Prerequisites / Notice | Basic knowledge in biology and chemistry | ||||