Karin Berger Büter: Catalogue data in Autumn Semester 2024 |
| Name | Dr. Karin Berger Büter |
| Address | bbi Emeligarten 6 breeding botanicals international 8592 Uttwil SWITZERLAND |
| Telephone | 071 669 37 81 |
| bekarin@ethz.ch | |
| Department | Chemistry and Applied Biosciences |
| Relationship | Lecturer |
| Number | Title | ECTS | Hours | Lecturers | |||||||||||||||||||||||||||||||||||||||||
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| 535-0360-00L | Evidence Based Phytotherapy | 1 credit | 1V | K. Berger Büter, S. Nicolussi | |||||||||||||||||||||||||||||||||||||||||
| Abstract | Based on epidemiology, economic importance and evidence-based medicine, basic principles of rational phytotherapy will be discussed: a) Identification of drug candidates, b) registration requirements, c) criteria to assess efficacy, d) biomarkers and pharmacokinetics, e) safety and f) principles of extract generation. Important prototypes will be discussed | ||||||||||||||||||||||||||||||||||||||||||||
| Learning objective | Content and aim of the lecture: Students should learn about the importance of rational (= evidence-based) pharmacotherapy with herbal extracts and know which factors influence the quality of such medicinal products. The following topics are covered: How are interesting development candidates identified. What are the strategies? What are the regulatory requirements (traditional use, well-established use, new herbal entities)? Determination of efficacy from (animal/human studies, biomarkers) Quality of clinical studies Pharmacokinetics of phytopharmaceuticals Safety (toxicity, adverse effects, interactions) Pharmaceutical quality Varietal purity (wild collections, cultivation) Influence of genetic variability on extract quality Ensuring consistent quality Which extraction methods? The topics are explained and critically discussed using various phytopharmaceuticals as examples (see programme below). | ||||||||||||||||||||||||||||||||||||||||||||
| Content | Effektive Zeiten 15.45 - 16.30; 16.45-17.30) Programm: 1) 18.09.2024 – KB - Online Aufzeichnung (link wird später bekannt gegeben) Einführung : Qualität Arzneipflanzen-Fertigprodukte, Monographien (Kommission E, ESCOP, HMPC), Unterschiede hinsichtlich des Registrierungsstatus und -anforderungen: traditional use, well established use und new herbal entities; Extrakte, Qualität Arzneidrogen 2) 25.09.2024 – SN - Präsenz: Phasen der klinischen Entwicklung, Grundbegriffe der evidenzbasierten Medizin; Hypericum perforatum 3) 02.10.2024 – SN - Präsenz: Echinacea; Pelargonium spp. 4) 09.10.2024 – SN - Präsenz: Lavandula oleum; Cimicifuga (Actea) racemosa 5) 16.10.2024 – KB - Präsenz: Phytotherapie bei funktionalen Darmbeschwerden; Serenoa repens 6) 23.10.2024 SN / KB - Präsenz Cannabis sativa; Silybum marianum 7) 30.10.2024 – KB - Präsenz Prüfung (MC) KB = Karin Berger Büter SN = Simon Nicolussi Die Auswahl der Pflanzen kann sich ev. noch ändern. | ||||||||||||||||||||||||||||||||||||||||||||
| Lecture notes | The scripts will be sent to the participants via email before the respective lectures | ||||||||||||||||||||||||||||||||||||||||||||
Competencies |
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| 751-4104-00L | Alternative Crops | 2 credits | 2V | A. Walter, K. Berger Büter | |||||||||||||||||||||||||||||||||||||||||
| Abstract | Few crops dominate the crop rotations worldwide. Following the goal of an increased agricultural biodiversity, species such as buckwheat but also medicinal plants might become more important in future. The biology, physiology, stress tolerance and central aspects of the value-added chain of the above-mentioned and of other alternative crops will be depicted. | ||||||||||||||||||||||||||||||||||||||||||||
| Learning objective | During this course, students learn to assess the potential of different minor or alternative crops compared to the dominant major crops based on their biological and agronomical features. Each student will assess and present a specific alternative crop of his or her choice based on information from scientific articles and Wikipedia. Wikipedia-entries will be generated. | ||||||||||||||||||||||||||||||||||||||||||||
| Competencies |
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