Volodymyr Korkhov: Katalogdaten im Herbstsemester 2023 |
| Name | Herr Prof. Dr. Volodymyr Korkhov |
| Lehrgebiet | Membranproteine und Signaltransduktion |
| Adresse | Dep. Biologie OSRA/001 Paul Scherrer Institut 5232 Villigen PSI SWITZERLAND |
| volodymyr.korkhov@mol.biol.ethz.ch | |
| Departement | Biologie |
| Beziehung | Ausserordentlicher Professor |
| Nummer | Titel | ECTS | Umfang | Dozierende | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| 551-0336-00L | Methods in Cellular Biochemistry  Number of participants limited to 19. The enrolment is done by the D-BIOL study administration. | 6 KP | 7P | I. Zemp, T. Kleele, V. Korkhov, U. Kutay, T. Michaels, M. Peter | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Kurzbeschreibung | Students will learn about biochemical approaches to analyze cellular functions. The course consists of practical projects in small groups, lectures and literature discussions. The course concludes with the presentation of results at a poster session. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Lernziel | Students will learn to design, carry out and assess experiments using current biochemical and cell biological strategies to analyze cellular functions in model systems. In particular they will learn novel imaging techniques along with biochemical approaches to understand fundamental cellular pathways. Furthermore, they will learn to assess strengths and limitations of the different approaches and be able to discuss their validity for the analysis of cellular functions. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Literatur | Documentation and recommended literature (review articles and selected primary literature) will be provided during the course. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Voraussetzungen / Besonderes | This course will be taught in English. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Kompetenzen |
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| 551-0351-00L | Membrane Biology Number of participants limited to 12. The enrolment is done by the D-BIOL study administration. | 6 KP | 7P | V. Korkhov, U. Kutay, S. C. Zeeman | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Kurzbeschreibung | The course will introduce the students to the key concepts in membrane biology and will allow them to be involved in laboratory projects related to that broad field. The course will consist of lectures, literature discussions, and practical laboratory work in small groups. Results of the practical projects will be presented during the poster session at the end of the course. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Lernziel | The aim of the course is to expose the students to a wide range of modern research areas encompassed by the field of membrane biology. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Inhalt | Students will be engaged in research projects aimed at understanding the biological membranes at the molecular, organellar and cellular levels. Students will design and perform experiments, evaluate experimental results, analyze the current scientific literature and understand the relevance of their work in the context of the current state of the membrane biology field. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Skript | No script | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Literatur | The recommended literature, including reviews and primary research articles, will be provided during the course | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Voraussetzungen / Besonderes | The course will be taught in English. All general lectures will be held at ETH Hoenggerberg. Students will be divided into small groups to carry out experiments at ETH or at the Paul Scherrer Institute. Travel to the Paul Scherrer Institute will be by public transportation. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Kompetenzen |
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| 551-1005-00L | Bioanalytics | 4 KP | 4G | P. Picotti, F. Allain, V. Korkhov, M. Pilhofer, R. Schlapbach, K. Weis, K. Wüthrich, weitere Dozierende | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Kurzbeschreibung | Der Kurs gibt eine Einführung in die wichtigsten der modernen biologischen Forschung zugrunde liegenden Labortechniken. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Lernziel | Für jede der besprochenen Techniken können die Studierenden am Ende des Kurses erklären: a) die physikalischen, chemischen und biologischen Prinzipien die der Technik zugrunde liegen, b) welche Anforderungen Technik an die verwendeten Proben stellt c) welche Rohdaten erhoben werden d) welche Annahmen und Zusatzdaten bei der Interpretation der Daten verwendet werden. e) wie die Daten und die Resultate der Analyse benutzt werden um biologische Fragen zu beantworten. Am Ende des Kurses werden die Studierenden in der Lage sein unter den besprochenen Techniken diejenigen auszuwählen, die am besten geeignet sind um eine bestimmte biologische Frage zu beantworten. Sie werden zusätzlich in der Lage sein die Vor- und Nachteile der in Frage kommenden Techniken zu diskutieren und zu beschreiben wie verschiedene Techniken kombiniert werden können um ein umfassenderes Verständnis der biologische Frage zu erhalten. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Inhalt | Der Kurs wird aus einer Kombination von Vorlesungen, Selbststudiumseinheiten und Übungen bestehen. Der Fokus des Kurses liegt auf folgenden Techniken: -DNA Sequenzierung - Chromatographische Techniken - Massenspektrometrie - UV/Vis- und Fluoreszensspektroskopie - Lichtmikroskopie - Elektronenmikroskopie - Röntgenkristallographie - NMR Spektroskopie | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Skript | Der Kurs wird durch eine Moodle Seite unterstützt auf der für den Kurs notwendigen Materialen zur Verfügung gestellt werden. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Kompetenzen |
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| 551-1303-00L | Cellular Biochemistry of Health and Disease | 4 KP | 2S | T. Kleele, V. Korkhov, G. Neurohr, V. Panse, M. Peter, A. E. Smith, F. van Drogen | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Kurzbeschreibung | During this Masters level seminar style course, students will explore current research topics in cellular biochemistry focused on the structure, function and regulation of selected cell components, and the consequences of dysregulation for pathologies. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Lernziel | Students will work with experts toward a critical analysis of cutting-edge research in the domain of cellular biochemistry, with emphasis on normal cellular processes and the consequences of their dysregulation. At the end of the course, students will be able to evaluate, critically discuss and write about scientific articles in the research area of cellular biochemistry, and they will identify open testable research questions. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Inhalt | Guided by an expert in the field, students will engage in classical round-table style discussions of current literature with occasional frontal presentations. Students will alternate as discussion leaders throughout the semester, with the student leader responsible to briefly summarize key general knowledge and context of the assigned primary research paper. Together with the faculty expert, all students will participate in discussion of the primary paper, including the foundation of the biological question, specific questions addressed, key methods, key results, remaining gaps and research implications. By the end of the semester, students will formulate their ideas about open testable research questions that extend from the published work. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Literatur | The literature will be provided during the course | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Voraussetzungen / Besonderes | The course will be taught in English. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Kompetenzen |
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