Stefanie Jonas: Catalogue data in Autumn Semester 2023 |
| Name | Prof. Dr. Stefanie Jonas |
| Field | RNA Biology and Disease |
| Address | Inst. f. Molekularbiol.u.Biophysik ETH Zürich, HPP L 24 Hönggerbergring 64 8093 Zürich SWITZERLAND |
| Telephone | +41 44 633 07 22 |
| stefanie.jonas@mol.biol.ethz.ch | |
| Department | Biology |
| Relationship | Associate Professor |
| Number | Title | ECTS | Hours | Lecturers | |||||||||||||||||||||||||||||||||||||||||
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| 551-1309-00L | RNA-Biology  Number of participants limited to 17. The enrolment is done by the D-BIOL study administration. | 6 credits | 7P | F. Allain, J. Corn, J. Hall, M. Jinek, S. Jonas, B. Mateescu, R. Santoro, O. Voinnet | |||||||||||||||||||||||||||||||||||||||||
| Abstract | Introduction to the diversity of current RNA-research at all levels from structural biology to systems biology using mainly model systems like S. cerevisiae (yeast), mammalian cells. | ||||||||||||||||||||||||||||||||||||||||||||
| Learning objective | The students will obtain an overview about the diversity of current RNA-research. They will learn to design experiments and use techniques necessary to analyze different aspects of RNA biology. Through lectures and literature seminars, they will learn about the burning questions of RNA research and discuss approaches to address these questions experimentally. In practical lab projects the students will work in one of the participating laboratories. Finally, they will learn how to present and discuss their data in an appropriate manner. Student assessment is a graded semester performance based on individual performance in the laboratory, the written exam and the poster presentation. | ||||||||||||||||||||||||||||||||||||||||||||
| Literature | Documentation and recommended literature will be provided at the beginning and during the course. | ||||||||||||||||||||||||||||||||||||||||||||
| Prerequisites / Notice | The course will be taught in English. | ||||||||||||||||||||||||||||||||||||||||||||
Competencies |
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| 551-1407-00L | RNA Biology Lecture Series I: Transcription & Processing & Translation Does not take place this semester. | 4 credits | 2V | F. Allain, N. Ban, S. Jonas, U. Kutay, further lecturers | |||||||||||||||||||||||||||||||||||||||||
| Abstract | This course covers aspects of RNA biology related to gene expression at the posttranscriptional level. These include RNA transcription, processing, alternative splicing, editing, export and translation. | ||||||||||||||||||||||||||||||||||||||||||||
| Learning objective | The students should obtain an understanding of these processes, which are at work during gene expression. | ||||||||||||||||||||||||||||||||||||||||||||
| Content | Transcription & 3'end formation ; splicing, alternative splicing, RNA editing; the ribosome & translation, translation regulation, RNP biogenesis & nuclear export, mRNA surveillance & mRNA turnover; signal transduction & RNA. | ||||||||||||||||||||||||||||||||||||||||||||
| Prerequisites / Notice | Basic knowledge of cell and molecular biology. | ||||||||||||||||||||||||||||||||||||||||||||