Detailed discussion of selected modern transition metal catalyzed reactions from a synthetic and mechanistic viewpoint
Lernziel
Understanding and critical evaluation of current research in transition metal catalysis. Design of mechanistic experiments to elucidate reaction mechanisms. Synthetic relevance of transition metal catalysis. Students will also learn about writing an original research proposal during a workshop.
Inhalt
Detailed discussion of selected modern transition metal catalyzed reactions from a synthetic and mechanistic viewpoint. Synthetic applications of these reactions. Introduction and application of tools for the elucidation of mechanisms. Selected examples of topics include: C-H activation, C-O activation, C-C activation, redox active ligands, main group redox catalysis, bimetallic catalysis.
Skript
Lecture slides will be provided online. A Handout summarizing important concepts in organometallic and physical organic chemistry will also be provided. Useful references and handouts will also be provided during the workshop.
Primary literature and review articles will be cited during the course.
The following textbooks can provide useful support for the course:
- Anslyn and Dougherty, Modern Physical Organic Chemistry, 1st Ed., University Science Books. - Crabtree R., The Organometallic Chemistry of the Transition Metals, John Wiley & Sons, Inc. - Hartwig J., Organotransition Metal Chemistry: From Bonding to Catalysis, University Science Books. - J. P. Collman, L. S. Hegedus, J. R. Norton, R. G. Finke, Principles and Applications of Organotransition Metal Chemistry.
Voraussetzungen / Besonderes
Required level: Courses in organic and physical chemistry (kinetics in particular) of the first and second year as well as ACI and III
Kompetenzen
Fachspezifische Kompetenzen
Konzepte und Theorien
geprüft
Methodenspezifische Kompetenzen
Analytische Kompetenzen
geprüft
Problemlösung
geprüft
Persönliche Kompetenzen
Anpassung und Flexibilität
geprüft
Kreatives Denken
geprüft
Kritisches Denken
geprüft
Leistungskontrolle
Information zur Leistungskontrolle (gültig bis die Lerneinheit neu gelesen wird)
Leistungskontrolle als Semesterkurs