Introduction to the organizational principles of the nucleus using budding yeast, drosophila and vertebrate cells as model systems.
Lernziel
The aim of our course is to introduce the students to the organizational principles of the nucleus using budding yeast, drosophila and vertebrate cells as model systems. Emphasis is given to: • Establishment of nuclear identity and nuclear-cytoplasmic communication • Reorganization of the nucleus in aging • Animal cells during the generation of cell diversity and neuronal differentiation
By the end of the course, based on lectures, literature reading and practical lab work, the students will be able to formulate open questions concerning the function of the nucleus. Thus, the students will know about the mechanisms and consequences of nuclear-cytoplasmic compartmentalization, DNA clustering in the nucleus and cytoplasm during cell divisions and aging.
Inhalt
During this block-course, the students will - learn how organelles establish and maintain identity with a focus on the nucleus - discover the evolutionary and functional plasticity of the nucleus - design, apply, evaluate and compare experimental strategies
Students - in groups of 2 or max. 3 - will be integrated into a research project connected to the subject of the course, within one of the participating research groups.
Lectures and technical notes will be given and informal discussions held to provide you with the theoretical background.
Skript
About 1 week before course start you will be invited to express your preference for a practical lab project on the course moodle site. Optional papers linked to the projects shall support you in that choice. They can also serve as framework orientation for the practical parts of this block course.
Literatur
Documentation and recommended literature (review articles) will be provided during the course.
Kompetenzen
Fachspezifische Kompetenzen
Konzepte und Theorien
geprüft
Verfahren und Technologien
geprüft
Methodenspezifische Kompetenzen
Analytische Kompetenzen
geprüft
Entscheidungsfindung
geprüft
Problemlösung
geprüft
Projektmanagement
gefördert
Soziale Kompetenzen
Kommunikation
geprüft
Kooperation und Teamarbeit
geprüft
Persönliche Kompetenzen
Anpassung und Flexibilität
gefördert
Kreatives Denken
gefördert
Kritisches Denken
geprüft
Integrität und Arbeitsethik
gefördert
Selbstbewusstsein und Selbstreflexion
gefördert
Leistungskontrolle
Information zur Leistungskontrolle (gültig bis die Lerneinheit neu gelesen wird)
Repetition nur nach erneuter Belegung der Lerneinheit möglich.
Zusatzinformation zum Prüfungsmodus
Only the main examiner is listed above, the additional examiners are the other lecturers of the course.
Students are obliged to be present throughout the block course. Cancellation: If you have to deregister from a course that has been assigned to you (just emergency reasons), please notify in written the course coordinator at least four weeks before the course starts, for courses in the 1st quarter, a cancellation period of one week applies. The study secretariat D-BIOL must also be informed (email CC to studies@biol.ethz.ch) so that the enrollment is deleted. Otherwise the course is considered as "failed".