227-0393-10L Bioelectronics and Biosensors
| Semester | Autumn Semester 2021 |
| Lecturers | J. Vörös, M. F. Yanik |
| Periodicity | yearly recurring course |
| Language of instruction | English |
| Abstract | The course introduces bioelectricity and the sensing concepts that enable obtaining information about neurons and their networks. The sources of electrical fields and currents in the context of biological systems are discussed. The fundamental concepts and challenges of measuring bioelectronic signals and the basic concepts to record optogenetically modified organisms are introduced. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Learning objective | During this course the students will: - learn the basic concepts of bioelectronics - be able to solve typical problems in bioelectronics - learn about the remaining challenges in this field | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Content | Lecture 1. Introduction to the field of bioelectronics and its challenges Sources of bioelectronic signals L2. Membrane and Transport L3. Action potential and Hodgkin-Huxley L4. Action potential and Hodgkin-Huxley 2 Measuring bioelectronic signals L5. Detection and Noise L6. Measuring currents in solutions, nanopore sensing and patch clamp pipettes L7. Measuring potentials in solution and core conductance L8. Measuring electronic signals with wearable electronics, ECG, EEG L9. Measuring mechanical signals with bioelectronics In vivo stimulation and recording L10. Functional electric stimulation L11. In vivo electrophysiology Optical recording and control of neurons (optogenetics) L12. Measuring neurons optically, fundamentals of optical microscopy L13. Fluorescent probes and scanning microscopy, optogenetics, in vivo microscopy L14. Measuring chemical signals | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Lecture notes | The course has its own script including the exercises. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Prerequisites / Notice | The course requires an open attitude to the interdisciplinary approach of bioelectronics. In addition, it requires undergraduate entry-level familiarity with electric & magnetic fields/forces, resistors, capacitors, electric circuits, differential equations, calculus, probability calculus, Fourier transformation & frequency domain, lenses / light propagation / refractive index, pressure, diffusion. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Competencies |
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