551-0337-00L  Cell Biology of the Nucleus

SemesterAutumn Semester 2024
LecturersR. Kroschewski, Y. Barral, M. Jagannathan, S. Jessberger, K. Weis
Periodicityyearly recurring course
Language of instructionEnglish
CommentNumber of participants limited to 14.
The enrolment is done by the D-BIOL study administration.



Courses

NumberTitleHoursLecturers
551-0337-00 PCell Biology of the Nucleus
Permission from lecturers required for all students.
Block course in the 1st semester quarter.
100s hrs
Tue/112:45-16:30HPM E 7 »
Wed/107:45-16:30HPM E 7 »
Thu/107:45-16:30HPM E 7 »
Fri/107:45-16:30HPM E 7 »
R. Kroschewski, Y. Barral, M. Jagannathan, S. Jessberger, K. Weis

Catalogue data

AbstractIntroduction to the organizational principles of the nucleus using budding yeast, drosophila and vertebrate cells as model systems.
Learning objectiveThe aim of our course is to introduce the students to the organizational principles of the nucleus using budding yeast, drosophila and vertebrate cells as model systems. Emphasis is given to:
• Establishment of nuclear identity and nuclear-cytoplasmic communication
• Reorganization of the nucleus in aging
• Animal cells during the generation of cell diversity and neuronal differentiation

By the end of the course, based on lectures, literature reading and practical lab work, the students will be able to formulate open questions concerning the function of the nucleus. Thus, the students will know about the mechanisms and consequences of nuclear-cytoplasmic compartmentalization, DNA clustering in the nucleus and cytoplasm during cell divisions and aging.
ContentDuring this block-course, the students will
- learn how organelles establish and maintain identity with a focus on the nucleus
- discover the evolutionary and functional plasticity of the nucleus
- design, apply, evaluate and compare experimental strategies


Students - in groups of 2 or max. 3 - will be integrated into a research project connected to the subject of the course, within one of the participating research groups.

Lectures and technical notes will be given and informal discussions held to provide you with the theoretical background.
Lecture notesAbout 1 week before course start you will be invited to express your preference for a practical lab project on the course moodle site.
Optional papers linked to the projects shall support you in that choice. They can also serve as framework orientation for the practical parts of this block course.
LiteratureDocumentation and recommended literature (review articles) will be provided during the course.
CompetenciesCompetencies
Subject-specific CompetenciesConcepts and Theoriesassessed
Techniques and Technologiesassessed
Method-specific CompetenciesAnalytical Competenciesassessed
Decision-makingassessed
Problem-solvingassessed
Project Managementfostered
Social CompetenciesCommunicationassessed
Cooperation and Teamworkassessed
Personal CompetenciesAdaptability and Flexibilityfostered
Creative Thinkingfostered
Critical Thinkingassessed
Integrity and Work Ethicsfostered
Self-awareness and Self-reflection fostered

Performance assessment

Performance assessment information (valid until the course unit is held again)
Performance assessment as a semester course
ECTS credits6 credits
ExaminersR. Kroschewski
Typegraded semester performance
Language of examinationEnglish
RepetitionRepetition only possible after re-enrolling for the course unit.
Additional information on mode of examinationOnly the main examiner is listed above, the additional examiners are the other lecturers of the course.

Students are obliged to be present throughout the block course.
Cancellation: If you have to deregister from a course that has been assigned to you (just emergency reasons), please notify in written the course coordinator at least four weeks before the course starts, for courses in the 1st quarter, a cancellation period of one week applies. The study secretariat D-BIOL must also be informed (email CC to studies@biol.ethz.ch) so that the enrollment is deleted. Otherwise the course is considered as "failed".

Learning materials

 
Moodle courseMoodle-Kurs / Moodle course
Only public learning materials are listed.

Groups

No information on groups available.

Restrictions

GeneralPermission from lecturers required for all students

Offered in

ProgrammeSectionType
Biology BachelorBlock Courses in 1st Quarter of the SemesterWInformation