Search result: Catalogue data in Autumn Semester 2021
Pharmaceutical Sciences Bachelor  | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
 Bachelor Studies (Programme Regulations 2020) | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| First Year Compulsory Subjects | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| First Year Examinations | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| First Year Examination Block 1 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Number | Title | Type | ECTS | Hours | Lecturers | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| 529-1001-01L | General Chemistry (for Biol./Pharm.Sc.) | O | 4 credits | 4V + 2U | J. Cvengros | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Abstract | The lecture deals with a number of basic chemistry concepts. These include (amongst others) chemical reactions, energy transfer during chemical reactions, properties of ionic and covalent bonds, Lewis structures, properties of solutions, kinetics, thermodynamics, acid-base equilibria, electrochemistry and properties of metal complexes. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Learning objective | The course is designed to provide an understanding of the basic principles and concepts of general and inorganic chemistry. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Literature | Charles E. Mortimer, CHEMIE - DAS BASISWISSEN DER CHEMIE. 12. Auflage, Georg Thieme Verlag Stuttgart, 2015. Weiterführende Literatur: Theodore L. Brown, H. Eugene LeMay, Bruce E. Bursten, CHEMIE. 10. Auflage, Pearson Studium, 2011. (deutsch) Catherine Housecroft, Edwin Constable, CHEMISTRY: AN INTRODUCTION TO ORGANIC, INORGANIC AND PHYSICAL CHEMISTRY, 3. Auflage, Prentice Hall, 2005.(englisch) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| 529-1011-00L | Organic Chemistry I (for Biol./Pharm.Sc./HST)  | O | 4 credits | 4G | C. Thilgen | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Abstract | Fundamentals of Organic Chemistry: molecular structure. Bonding and functional groups; nomenclature; resonance and aromaticity; stereochemistry; conformation; bond strength; organic acids and bases; basic reaction thermodynamics and kinetcs; reactive intermediates: carbanions, carbenium ions and radicals. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Learning objective | Understanding the basic concepts and definitions of organic chemistry. Knowledge of the functional groups and classes of compounds that are important in biological systems. Foundations for the understanding of the relationship between structure and reactivity. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Content | Organic molecules: Isolation, separation and characterization of organic compounds. Classical structure theory: constitution, covalent bonding, bonding geometry, functional groups, classes of compounds, nomenclature. Electron delocalization: resonance, aromaticity. Stereochemistry: chirality, configuration, topicity. Conformational analysis. Bond energies, non-covalent interactions. Organic acids and bases. Basic reaction thermodynamics and kinetcs; reactive intermediates: carbanions, carbenium ions and radicals. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Lecture notes | Printed lecture notes are available. Exercises, answer keys and other handouts can be downloaded from the Moodle course "Organic Chemistry I" of the current semester (https://moodle-app2.let.ethz.ch). | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Literature | • Basisbuch Organische Chemie. Carsten Schmuck, Pearson Studium, 2018. (Kompaktes Lehrbuch für die ersten beiden Semester; 412 Seiten). • Organische Chemie. K. Peter C. Vollhardt, Neil E. Schore, Übers. hrsg. von Holger Butenschön, 5. Aufl., Wiley-VCH, 2011. • Organic Chemistry: Structure and Function. K. Peter C. Vollhardt, Neil E. Schore, 8th ed., W. H. Freeman & Company, 2018. • Organic Chemistry. T. W. Graham Solomons, Craig B. Fryhle, Scott A. Snyder, 11th ed., internat. stud. vers., Wiley, Hoboken, N. J., 2014. • Organische Chemie. J. Clayden, N. Greeves, S. Warren, 2. Aufl., Springer Spektrum, 2013. • Organic Chemistry. J. Clayden, N. Greeves, S. Warren, 2nd ed., Oxford University Press, 2012. • Organische Chemie. Paula Y. Bruice, 5. akt. Aufl., Pearson. • Organic Chemistry (Global Edition). Paula Y. Bruice, 8th ed., Pearson. • Essential Organic Chemistry (Global Edition). Paula Y. Bruice, 3rd ed., Pearson. (Designed for a one-term course) • Organic Chemistry I as a Second Language – Translating the basic concepts. Taschenbuch mit Übungen: 656 Seiten; David R. Klein; Verlag: John Wiley & Sons Inc; ISBN-10: 0470198699, ISBN-13: 978-0470198698. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Prerequisites / Notice | The course consists of lectures (36 hours) and problem-solving lessons (20 hours, groups of ca. 25 people). In addition, online exercises are available in the e-learning environment Moodle (Course OC I). | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| 551-0125-00L | Fundamentals of Biology I: From Molecules to the Biochemistry of Cells | O | 6 credits | 5G | J. Vorholt-Zambelli, N. Ban, R. Glockshuber, K. Locher, J. Piel | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Abstract | The lecture provides an introduction to the basics of biochemistry and molecular biology as well as evolutionary principles. The focus is on bacteria and archaea under consideration of universal concepts. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Learning objective | Introduction to biochemistry, molecular biology and evolutionary principles | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Content | The lecture introduces biology as an interdisciplinary science. Links to physics and chemistry will manifest as biological processes that operate within the laws of thermodynamics and are rooted in elements, molecules and chemical reactions. The transition from geochemistry to biochemistry is discussed and considered in relation to the origin of life. Evolutionary principles are introduced and resulting processes are used as a guiding principle. Unifying concepts in biology are presented, including the structure and function of cellular macromolecules and the ways in which hereditary information is encoded, decoded and replicated. Central principles of universal energy conversion are looked at, starting from redox processes and focusing on bacteria and archaea. Finally, biological processes are put into an ecosystems perspective. The lecture is divided into different sections: 1. Geochemical perspectives on Earth and introduction to evolution 2. Building blocks of life 3. Macromolecules: Proteins 4. Membranes and transport across the plasma membrane 5. Universal mechanisms of inheritance, transcription and translation 6. Reaction Kinetics, binding equilibria and enzymatic catalysis 7. Essentials of Catabolism 8. Essentials of Anabolism 9. Metabolism and biogeochemical cycling of elements | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Lecture notes | The newly conceived lecture is supported by scripts. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Literature | The lecture is supported by scripts. The lecture contains elements of "Brock Biology of Microorganisms", Madigan et al. 15th edition, Pearson und "Biochemistry" (Stryer), Berg et al. 9th edition, Macmillan international. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| First Year Examination Block 2 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Number | Title | Type | ECTS | Hours | Lecturers | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| 535-0001-00L | Introduction to Pharmaceutical Sciences I | O | 2 credits | 2V | J. Hall, K.‑H. Altmann, M. Detmar, C. Halin Winter, J.‑C. Leroux, U. Quitterer, J. Scheuermann, R. Schibli, H. U. Zeilhofer | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Abstract | First identification with Pharmaceutical Sciences; motivation for profiling in the Natural Sciences, which are focused on within the first two years as a preparation for the specialized studies; sensitization for the duties and the responsibilities of a person with a federal diploma in Pharmacy; information about job opportunities. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Learning objective | First identification with Pharmaceutical Sciences; motivation for profiling in the Natural Sciences as a preparation for the specialized studies; sensitization for the duties and the responsibilities of a person with a federal diploma in Pharmacy; information about job opportunities. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Content | Introduction to Pharmaceutical Sciences by selected milestones of research and development. Overview on research activities at the Institute of Pharmaceutical Sciences that is focussed on drug delivery and development (from concepts to prototypes). Sensitization for communication skills and information management. Demonstration of job opportunities in community pharmacies, in the hospital, in industry, and in the public sector by experts in the different fields. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Lecture notes | Handouts for individual lectures. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Prerequisites / Notice | Interactive teaching | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| 401-0291-00L | Mathematics I | O | 6 credits | 4V + 2U | A. Caspar | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Abstract | Mathematics I/II is an introduction to one- and multidimensional calculus and linear algebra emphasizing on applications. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Learning objective | Students understand mathematics as a language for modeling and as a tool for solving practical problems in natural sciences. Students can analyze models, describe solutions qualitatively or calculate them explicitly if need be. They can solve examples as well as their practical applications manually and using computer algebra systems. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Content | ## Eindimensionale diskrete Entwicklungen ## - linear, exponentiell, begrenzt, logistisch - Fixpunkte, diskrete Veränderungsrate - Folgen und Grenzwerte ## Funktionen in einer Variablen ## - Reproduktion, Fixpunkte - Periodizität - Stetigkeit ## Differentialrechnung (I) ## - Veränderungsrate/-geschwindigkeit - Differentialquotient und Ableitungsfunktion - Anwendungen der Ableitungsfunktion ## Integralrechnung (I) ## - Stammfunktionen - Integrationstechniken ## Gewöhnliche Differentialgleichungen (I) ## - Qualitative Beschreibung an Beispielen: Beschränkt, Logistisch, Gompertz - Stationäre Lösungen - Lineare DGL 1. Ordnung - Trennung der Variablen ## Lineare Algebra ## - Erste Arithmetische Aspekte - Matrizenrechnung - Eigenwerte / -vektoren - Quadratische LGS und Determinante | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Lecture notes | In Ergänzung zu den Vorlesungskapiteln der Lehrveranstaltungen fassen wir wichtige Sachverhalte, Formeln und weitere Ausführungen jeweils in einem Vademecum zusammen. Dabei gilt: * Die Skripte ersetzen nicht die Vorlesung und/oder die Übungen! * Ohne den Besuch der Lehrveranstaltungen verlieren die Ausführungen ihren Mehrwert. * Details entwickeln wir in den Vorlesungen und den Übungen, um die hier bestehenden Lücken zu schliessen. * Prüfungsrelevant ist, was wir in der Vorlesung und in den Übungen behandeln. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Literature | Siehe auch Lernmaterial > Literatur **Th. Wihler** Mathematik für Naturwissenschaften, 2 Bände: Einführung in die Analysis, Einführung in die Lineare Algebra; Haupt-Verlag Bern, UTB. **H. H. Storrer** Einführung in die mathematische Behandlung der Naturwissenschaften I; Birkhäuser. Via ETHZ-Bibliothek: https://link.springer.com/book/10.1007/978-3-0348-8598-0 **Ch. Blatter** Lineare Algebra; VDF auch als [pdf](<https://people.math.ethz.ch/~blatter/linalg.pdf>) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Prerequisites / Notice | ## Übungen und Prüfungen ## + Die Übungsaufgaben (inkl. Multiple-Choice) sind ein wichtiger Bestandteil der Lehrveranstaltung. + Es wird erwartet, dass Sie mindestens 75 % der wöchentlichen Serien bearbeiten und zur Korrektur einreichen. + Der Prüfungsstoff ist eine Auswahl von Themen aus Vorlesung und Übungen. Für eine erfolgreiche Prüfung ist die konzentrierte Bearbeitung der Aufgaben unerlässlich. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| 402-0073-00L | Physics I | O | 3 credits | 2V + 2U | T. M. Ihn | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Abstract | Introduction to the concepts and tools in physics with the help of demonstration experiments: mechanics and elements of quantum mechanics | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Learning objective | Students know and understand the basic ideas of the scientific description of nature. They understand the fundamental concepts and laws of mechanics and they are able to apply them in practical problems. They know the concepts of quantization and quantum numbers. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Content | 1. Description of Motion 2. The laws of Newton 3. Work and energy 4. Collision problems 5. Wave properties of particles 6. The atomic structure of matter | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Lecture notes | T. Ihn: Physics for Students in Biology and Pharmazeutical Sciences (unpublished lecture notes) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Literature | The lecture contains elements of: Paul A. Tipler and Gene P. Mosca, "Physik für Wissenschaftler und Ingenieure", Springer Spektrum. Feynman, Leighton, Sands, "The Feynman Lectures on Physics", Volume I (http://www.feynmanlectures.caltech.edu/) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| Additional First Year Courses | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Number | Title | Type | ECTS | Hours | Lecturers | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| 535-0667-00L | Communication and Social Competences | O | 1 credit | 1V | J. Stadelwieser | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Abstract | Introduction in basic skills for increasing the effectiveness and efficiency of students daily work. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Learning objective | Students . . . 1) know tools to "study in a paperless way"; have tried out these tools and made their own conscious choice of useful tools. 2) know tools to work efficiently and goal-oriented in teams. 3) can approach problems methodically correct; know important problem-solving techniques. 4) are able to handle scientific texts and sources correctly; know how to write scientific papers. 5) know how to avoid social problems in workingteams and how to solve them when they exist. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Content | corresponding learning goals | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Lecture notes | Handouts and working papers. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Literature | - Braun Walter, Die (Psycho-) Logik des Entscheidens, Fallstricke, Strategien und Techniken im Umgang mit schwierigen Situationen, Huber, 2010 - Haberfellner/de Weck, Systems Engineering, Grundlagen und Anwendungen, Zürich 2015. - Metzger Christoph, Wie lerne ich?: Ein Fachbuch für Studierende, Sauerländer, 2010. - Stadelwieser Jürg, Kommunikation als Schlüssel zum Erfolg, Tobler, 2000 (vergriffen/Bibliothek). - Steiner Verena: Exploratives Lernen, Pendo, 2013. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Prerequisites / Notice | None | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| 535-1001-00L | Laboratory Course General Chemistry (for Biology and Pharmacy) Information about the practical course will be given on the first day. Register in myStudies as early as possible, because the fire protection courses take place separately before the internship starts. | O | 6 credits | 8P | S. Gruber, K.‑H. Altmann, J. Hall | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Abstract | Introduction to the practical work in a chemistry laboratory. The most important manipulations and techniques are treated, as well as the most fundamental chemical reaction types. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Learning objective | - Knowledge of the basic chemical laboratory methods - Basic knowledge of the scientific approach in experimenting - Observation and interpretation of chemical processes - Keeping of a reliable laboratory journal | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Content | - Simple chemical working techniques/methods - Separation techniques - Physical measurements: mass, volume, pH - Ionic solids (salts) - Acid/base chemistry, buffers - Redox reactions - Metal complexes - Titration methods and quantitative spectrometry - Introduction to qualitative analysis | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Lecture notes | Course manual in German (is handed out to the students at the begin of the lessons) Language: German, English upon request | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Literature | Basic Concepts of Chemistry, International Student Version, 8th Edition, Leo J. Malone, Theodore Dolter Wiley is a suitable textbook. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Prerequisites / Notice | This practical course causes costs for materials and chemicals. The costs are charged to the students at the end of semester. Safety conceptt: https://chab.ethz.ch/studium/bachelor1.html | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| Core Courses | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Number | Title | Type | ECTS | Hours | Lecturers | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| 252-0852-00L | Foundations of Computer Science | O | 4 credits | 2V + 2U | L. E. Fässler, M. Dahinden | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Abstract | Students learn to apply selected concepts and tools from computer science for working on interdisciplinary projects. The following topics are covered: modeling and simulations, introduction to programming, introduction matrices, managing data with lists and tables and with relational databases, universal methods for algorithm design. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Learning objective | The students learn to - understand the role of computer science in science, - to control computer and automate processes of problem solving by programming, - choose and apply appropriate tools from computer science, - process and analyze real-world data from their subject of study, - handle the complexity of real-world data. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Content | 1. The role of computer science in science 2. Introduction to Programming with Python 3. Modeling and simulations 4. Data management with lists and tables 5. Data management with a relational database 6. Introduction to Matrices | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Lecture notes | All materials for the lecture are available at www.gdi.ethz.ch | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Literature | L. Fässler, M. Dahinden, D. Komm, and D. Sichau: Einführung in die Programmierung mit Python und Matlab. Begleitunterlagen zum Onlinekurs und zur Vorlesung, 2016. ISBN: 978-3741250842. L. Fässler, M. Dahinden, and D. Sichau: Verwaltung und Analyse digitaler Daten in der Wissenschaft. Begleitunterlagen zum Onlinekurs und zur Vorlesung, 2017. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Prerequisites / Notice | This course is based on application-oriented learning. The students spend most of their time working through projects with data from natural science and discussing their results with teaching assistants. To learn the computer science basics there are electronic tutorials available. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| 401-0643-13L | Statistics II | O | 3 credits | 2V + 1U | M. Kalisch | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Abstract | Vertiefung von Statistikmethoden. Nach dem detailierten Fundament aus Statistik I liegt nun der Fokus auf konzeptueller Breite und konkreter Problemlösungsfähigkeit mit der Statistiksoftware R. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Learning objective | Nach diesem Kurs können Sie mit der Statistiksoftware R Daten einlesen, auf vielfältige Art verarbeiten und Grafiken für Berichte oder Vorträge exportieren. Sie verstehen die Konzepte von Methoden wie Lineare Regression (mit Faktoren, Interaktion, Modellwahl), ANOVA (1-weg, 2-weg), Chi-Quadrat-Test, Fisher-Test, GLMs, Mixed Models, Clustering, PCA und können diese mit der Statistiksoftware R in der Praxis umsetzen. Zudem kennen Sie die Grundprinzipien von gutem experimentellem Design und können bestehende Studien kritisch hinterfragen. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| 551-0127-00L | Fundamentals of Biology III: Multicellularity | O | 8 credits | 6G | M. Stoffel, M. Künzler, O. Y. Martin, U. Suter, S. Werner, A. Wutz, S. C. Zeeman | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Abstract | The lecture conveys the fundamental concepts underlying multicellularity with an emphasis on the molecular basis of multicellular biological systems and their functional integration into coherent wholes. The structural and functional specialization in multicellular organisms will be discussed by highlighting common and specific functions in fungi, plants, and animals (including humans). | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Learning objective | 1.Students can describe advantages and challenges associated with being multicellular and outline independent solutions that organisms have developed to cope with the challenges of complex multicellularity . 2.Students can explain how the internal and external structures of fungi, plants and animals function to support survival, growth, behavior, and reproduction. 3.Students can explain the basic pathways and mechanisms of cellular communication regulating cellular behavior (cell adhesion, metabolism, proliferation, reproduction, development). 4.Students can describe how a single cell develops from one cell into many, each with different specialized functions. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Content | The lecture introduces the structural and functional specialization in fungi, plants and animals, including humans. After providing an overview on the diversity of eukaryotic organisms, the lecture will discuss how fungi, plants, animals and humans have evolved structures and strategies to cope with the challenges of multicellularity. The molecular basis underlying communication, coordination and differentiation will be conveyed and complemented by key aspects of reproduction, metabolism development, and regeneration. Topics include form and function of fungi and plants, human anatomy and physiology, metabolism, cell signaling, adhesion, stem cells, regeneration, reproduction, and development. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Literature | Alberts et al. 'Molecular Biology of the Cell' 6th edition Smith A.M., et al. “Plant Biology” Garland Science, New York, Oxford Campbell “Biology”, 11th Edition | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Prerequisites / Notice | Some lecture are held in English. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| 376-0151-00L | Anatomy and Physiology I | O | 5 credits | 4V | D. P. Wolfer, K. De Bock, R. Fiore, S. Meissner, L. Slomianka, C. Spengler, M. Willecke | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Abstract | Basic knowledge of the anatomy and physiology of tissues, of the embryonal and postnatal development, the sensory organs, the neuro-muscular system, the cardiovascular system and the respiratory system. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Learning objective | Basic knowledge of human anatomy and physiology and basics of clinical pathophysiology. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Content | The lecture series provides a short overview of human anatomy and physiology Anatomy and Physiology I (fall term): Basics of cytology, histology, embryology; nervous system, sensory organs, muscles, cardiovascular system, respiratory system Anatomy and Physiology II (spring term): digestive tract, endocrine organs, metabolism and thermoregulation, skin, blood and immune system, urinary system, circadian rhythm, reproductive organs, pregnancy and birth. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Prerequisites / Notice | Requirements: 1st year, scientific part. Part of the course is read and checked in English. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| 535-0225-00L | Pharmaceutical Analytics I | O | 3 credits | 3G | C. Steuer | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Abstract | This course provides the basic concepts of pharmaceutical analytics in the context of pharmacopeial regulation by Ph. Eur and Ph. Helv. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Learning objective | Summarize the structure of the Ph. Eur. Summarize the most important pharmacopeias and their commonalities and differences (USP, JP, Ph.Eur., Ph. Helv.) Discuss the structure of a monograph Explain qualification of instruments and validation of methods Explain and compare most important analytical techniques for pharmacies and pharmaceutical industry | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Content | Knowledge in pharmaceutical analytics to fulfill regulatory equirements in pharmaceutical industry based on the pharmacopeia in force. Focus is set on method validation, equipment qualification, identification of functional groups and content determination of active pharmaceutical ingredients and excipients. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Lecture notes | The slides of the lectures will be provided. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Literature | Instrumentelle Analytik, G. Rücker, M. Neugebauer, G.G. Willems; Deutscher Apotheker Verlag, Stuttgart Arzneistoffanalyse; H. J. Roth, K. Eger, R. Troschütz; Deutscher Apotheker Verlag, Stuttgart Introduction to Pharmaceutical Chemical Analysis; S.H. Hansen, S. Pedersen-Bjergaard, K. Rasmussen; Wiley & Sons | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Prerequisites / Notice | Requirements for the practical course Pharmaceutical Analytics: SR 2013: 6 credits Analytics/Pharmaceutical Analytics or 36 credits of compulsory lectures 2nd year SR 2020: 7 credits Pharmazeutische Analytik I und II or 36 credits of compulsory lectures 2nd year | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Laboratory Courses | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Number | Title | Type | ECTS | Hours | Lecturers | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| 529-0229-00L | Practical Course Organic Chemistry (for Students of Biology and Pharmaceutical Sciences) Latest online enrolment is 10 days before the beginning of the semester. Students who did not pass the first-year examinations need the lecturers' written permission to take this course. | O | 8 credits | 12P | C. Thilgen, Y. Yamakoshi | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Abstract | Analytical part: basic operations for the separation of mixtures of organic compounds (recrystallization, distillation, extraction, chromatography) Synthetic part (main part): at least 8 synthetic steps (one- or two-step syntheses). | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Learning objective | Learn the basic techniques for the preparation and purification of organic compounds. Learn to take accurate notes of the experiments and to write reports. Deepen the understanding of reaction mechanisms. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Content | Analytical part: basic operations for the separation of mixtures of organic compounds (recrystallization, distillation, extraction, chromatography). Synthetic part (main part): at least 8 synthetic steps (one- or two-step syntheses) from the following classes of reactions: 1. nucleophilic substitution at C(sp3), 2. elimination or electrophilic addition to C=C, 3. electrophilic aromatic substitution, 4. oxidation, 5. reduction, 6. Grignard reaction, 7. synthesis of a carboxylic acid derivative, 8. Aldol-, Claisen-, Mannich-, Michael reaction or Robinson annulation. Introduction to database searches (Reaxys, SciFinder). | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Lecture notes | Documentation will be handed out at the beginning of the course. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Literature | 1) P. Wörfel, M. Bitzer, U. Claus, H. Felber, M. Hübel, B. Vollenweider, Laborpraxis (Bd. 1: Einführung, allgemeine Methoden; Bd. 2: Messmethoden; Bd. 3: Trennungsmethoden; Bd. 4: Analytische Methoden); Birkhäuser Verlag; Basel; 1990. 2) J. Leonard, B. Lygo, G. Procter; Advanced Practical Organic Chemistry; CRC Press Taylor & Francis Group; Boca Raton, FL; 2013. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Prerequisites / Notice | The basic reactions of Organic Chemistry and their mechanisms should be known (cf. course 529-1012-00L Organic Chemistry II for Students of Biology, Pharmaceutical Sciences, and Health Sci. and Tech.). As a prerequisite, all participants need to pass the "Safety Test HCI Chemie_V2 English" (see https://moodle-app2.let.ethz.ch). A printout of the certificate generated by the system needs to be presented to the teaching assistants prior to starting lab work. Safety conceptt: https://chab.ethz.ch/studium/bachelor1.html | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Competencies |
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