Search result: Catalogue data in Autumn Semester 2021

Pharmaceutical Sciences Bachelor Information
Bachelor Studies (Programme Regulations 2020)
First Year Compulsory Subjects
First Year Examinations
First Year Examination Block 1
NumberTitleTypeECTSHoursLecturers
529-1001-01LGeneral Chemistry (for Biol./Pharm.Sc.)O4 credits4V + 2UJ. Cvengros
AbstractThe lecture deals with a number of basic chemistry concepts. These include (amongst others) chemical reactions, energy transfer during chemical reactions, properties of ionic and covalent bonds, Lewis structures, properties of solutions, kinetics, thermodynamics, acid-base equilibria, electrochemistry and properties of metal complexes.
Learning objectiveThe course is designed to provide an understanding of the basic principles and concepts of general and inorganic chemistry.
LiteratureCharles E. Mortimer, CHEMIE - DAS BASISWISSEN DER CHEMIE. 12. Auflage, Georg Thieme Verlag Stuttgart, 2015.

Weiterführende Literatur:
Theodore L. Brown, H. Eugene LeMay, Bruce E. Bursten, CHEMIE. 10. Auflage, Pearson Studium, 2011. (deutsch)

Catherine Housecroft, Edwin Constable, CHEMISTRY: AN INTRODUCTION TO ORGANIC, INORGANIC AND PHYSICAL CHEMISTRY, 3. Auflage, Prentice Hall, 2005.(englisch)
CompetenciesCompetencies
Subject-specific CompetenciesConcepts and Theoriesassessed
Techniques and Technologiesassessed
Method-specific CompetenciesAnalytical Competenciesassessed
Decision-makingassessed
Media and Digital Technologiesfostered
Problem-solvingassessed
Project Managementfostered
Social CompetenciesCommunicationfostered
Cooperation and Teamworkfostered
Customer Orientationfostered
Leadership and Responsibilityfostered
Self-presentation and Social Influence fostered
Sensitivity to Diversityfostered
Negotiationfostered
Personal CompetenciesAdaptability and Flexibilityfostered
Creative Thinkingassessed
Critical Thinkingassessed
Integrity and Work Ethicsfostered
Self-awareness and Self-reflection fostered
Self-direction and Self-management assessed
529-1011-00LOrganic Chemistry I (for Biol./Pharm.Sc./HST) Restricted registration - show details O4 credits4GC. Thilgen
AbstractFundamentals of Organic Chemistry: molecular structure. Bonding and functional groups; nomenclature; resonance and aromaticity; stereochemistry; conformation; bond strength; organic acids and bases; basic reaction thermodynamics and kinetcs; reactive intermediates: carbanions, carbenium ions and radicals.
Learning objectiveUnderstanding the basic concepts and definitions of organic chemistry. Knowledge of the functional groups and classes of compounds that are important in biological systems. Foundations for the understanding of the relationship between structure and reactivity.
ContentOrganic molecules: Isolation, separation and characterization of organic compounds. Classical structure theory: constitution, covalent bonding, bonding geometry, functional groups, classes of compounds, nomenclature. Electron delocalization: resonance, aromaticity. Stereochemistry: chirality, configuration, topicity. Conformational analysis. Bond energies, non-covalent interactions. Organic acids and bases. Basic reaction thermodynamics and kinetcs; reactive intermediates: carbanions, carbenium ions and radicals.
Lecture notesPrinted lecture notes are available. Exercises, answer keys and other handouts can be downloaded from the Moodle course "Organic Chemistry I" of the current semester (https://moodle-app2.let.ethz.ch).
Literature• Basisbuch Organische Chemie. Carsten Schmuck, Pearson Studium, 2018. (Kompaktes Lehrbuch für die ersten beiden Semester; 412 Seiten).
• Organische Chemie. K. Peter C. Vollhardt, Neil E. Schore, Übers. hrsg. von Holger Butenschön, 5. Aufl., Wiley-VCH, 2011.
• Organic Chemistry: Structure and Function. K. Peter C. Vollhardt, Neil E. Schore, 8th ed., W. H. Freeman & Company, 2018.
• Organic Chemistry. T. W. Graham Solomons, Craig B. Fryhle, Scott A. Snyder, 11th ed., internat. stud. vers., Wiley, Hoboken, N. J., 2014.
• Organische Chemie. J. Clayden, N. Greeves, S. Warren, 2. Aufl., Springer Spektrum, 2013.
• Organic Chemistry. J. Clayden, N. Greeves, S. Warren, 2nd ed., Oxford University Press, 2012.
• Organische Chemie. Paula Y. Bruice, 5. akt. Aufl., Pearson.
• Organic Chemistry (Global Edition). Paula Y. Bruice, 8th ed., Pearson.
• Essential Organic Chemistry (Global Edition). Paula Y. Bruice, 3rd ed., Pearson. (Designed for a one-term course)
• Organic Chemistry I as a Second Language – Translating the basic concepts. Taschenbuch mit Übungen: 656 Seiten; David R. Klein; Verlag: John Wiley & Sons Inc; ISBN-10: 0470198699, ISBN-13: 978-0470198698.
Prerequisites / NoticeThe course consists of lectures (36 hours) and problem-solving lessons (20 hours, groups of ca. 25 people). In addition, online exercises are available in the e-learning environment Moodle (Course OC I).
CompetenciesCompetencies
Subject-specific CompetenciesConcepts and Theoriesassessed
Method-specific CompetenciesAnalytical Competenciesassessed
Social CompetenciesCommunicationfostered
Sensitivity to Diversityfostered
Personal CompetenciesCreative Thinkingfostered
Critical Thinkingfostered
Integrity and Work Ethicsfostered
Self-awareness and Self-reflection fostered
Self-direction and Self-management fostered
551-0125-00LFundamentals of Biology I: From Molecules to the Biochemistry of CellsO6 credits5GJ. Vorholt-Zambelli, N. Ban, R. Glockshuber, K. Locher, J. Piel
AbstractThe lecture provides an introduction to the basics of biochemistry and molecular biology as well as evolutionary principles. The focus is on bacteria and archaea under consideration of universal concepts.
Learning objectiveIntroduction to biochemistry, molecular biology and evolutionary principles
ContentThe lecture introduces biology as an interdisciplinary science. Links to physics and chemistry will manifest as biological processes that operate within the laws of thermodynamics and are rooted in elements, molecules and chemical reactions. The transition from geochemistry to biochemistry is discussed and considered in relation to the origin of life. Evolutionary principles are introduced and resulting processes are used as a guiding principle. Unifying concepts in biology are presented, including the structure and function of cellular macromolecules and the ways in which hereditary information is encoded, decoded and replicated. Central principles of universal energy conversion are looked at, starting from redox processes and focusing on bacteria and archaea. Finally, biological processes are put into an ecosystems perspective.

The lecture is divided into different sections:
1. Geochemical perspectives on Earth and introduction to evolution
2. Building blocks of life
3. Macromolecules: Proteins
4. Membranes and transport across the plasma membrane
5. Universal mechanisms of inheritance, transcription and translation
6. Reaction Kinetics, binding equilibria and enzymatic catalysis
7. Essentials of Catabolism
8. Essentials of Anabolism
9. Metabolism and biogeochemical cycling of elements
Lecture notesThe newly conceived lecture is supported by scripts.
LiteratureThe lecture is supported by scripts.
The lecture contains elements of "Brock Biology of Microorganisms", Madigan et al. 15th edition, Pearson und "Biochemistry" (Stryer), Berg et al. 9th edition, Macmillan international.
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