Search result: Catalogue data in Autumn Semester 2021
Pharmaceutical Sciences Bachelor  | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
 Bachelor Studies (Programme Regulations 2020) | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| First Year Compulsory Subjects | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| First Year Examinations | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| First Year Examination Block 1 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Number | Title | Type | ECTS | Hours | Lecturers | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| 529-1001-01L | General Chemistry (for Biol./Pharm.Sc.) | O | 4 credits | 4V + 2U | J. Cvengros | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Abstract | The lecture deals with a number of basic chemistry concepts. These include (amongst others) chemical reactions, energy transfer during chemical reactions, properties of ionic and covalent bonds, Lewis structures, properties of solutions, kinetics, thermodynamics, acid-base equilibria, electrochemistry and properties of metal complexes. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Learning objective | The course is designed to provide an understanding of the basic principles and concepts of general and inorganic chemistry. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Literature | Charles E. Mortimer, CHEMIE - DAS BASISWISSEN DER CHEMIE. 12. Auflage, Georg Thieme Verlag Stuttgart, 2015. Weiterführende Literatur: Theodore L. Brown, H. Eugene LeMay, Bruce E. Bursten, CHEMIE. 10. Auflage, Pearson Studium, 2011. (deutsch) Catherine Housecroft, Edwin Constable, CHEMISTRY: AN INTRODUCTION TO ORGANIC, INORGANIC AND PHYSICAL CHEMISTRY, 3. Auflage, Prentice Hall, 2005.(englisch) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| 529-1011-00L | Organic Chemistry I (for Biol./Pharm.Sc./HST)  | O | 4 credits | 4G | C. Thilgen | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Abstract | Fundamentals of Organic Chemistry: molecular structure. Bonding and functional groups; nomenclature; resonance and aromaticity; stereochemistry; conformation; bond strength; organic acids and bases; basic reaction thermodynamics and kinetcs; reactive intermediates: carbanions, carbenium ions and radicals. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Learning objective | Understanding the basic concepts and definitions of organic chemistry. Knowledge of the functional groups and classes of compounds that are important in biological systems. Foundations for the understanding of the relationship between structure and reactivity. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Content | Organic molecules: Isolation, separation and characterization of organic compounds. Classical structure theory: constitution, covalent bonding, bonding geometry, functional groups, classes of compounds, nomenclature. Electron delocalization: resonance, aromaticity. Stereochemistry: chirality, configuration, topicity. Conformational analysis. Bond energies, non-covalent interactions. Organic acids and bases. Basic reaction thermodynamics and kinetcs; reactive intermediates: carbanions, carbenium ions and radicals. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Lecture notes | Printed lecture notes are available. Exercises, answer keys and other handouts can be downloaded from the Moodle course "Organic Chemistry I" of the current semester (https://moodle-app2.let.ethz.ch). | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Literature | • Basisbuch Organische Chemie. Carsten Schmuck, Pearson Studium, 2018. (Kompaktes Lehrbuch für die ersten beiden Semester; 412 Seiten). • Organische Chemie. K. Peter C. Vollhardt, Neil E. Schore, Übers. hrsg. von Holger Butenschön, 5. Aufl., Wiley-VCH, 2011. • Organic Chemistry: Structure and Function. K. Peter C. Vollhardt, Neil E. Schore, 8th ed., W. H. Freeman & Company, 2018. • Organic Chemistry. T. W. Graham Solomons, Craig B. Fryhle, Scott A. Snyder, 11th ed., internat. stud. vers., Wiley, Hoboken, N. J., 2014. • Organische Chemie. J. Clayden, N. Greeves, S. Warren, 2. Aufl., Springer Spektrum, 2013. • Organic Chemistry. J. Clayden, N. Greeves, S. Warren, 2nd ed., Oxford University Press, 2012. • Organische Chemie. Paula Y. Bruice, 5. akt. Aufl., Pearson. • Organic Chemistry (Global Edition). Paula Y. Bruice, 8th ed., Pearson. • Essential Organic Chemistry (Global Edition). Paula Y. Bruice, 3rd ed., Pearson. (Designed for a one-term course) • Organic Chemistry I as a Second Language – Translating the basic concepts. Taschenbuch mit Übungen: 656 Seiten; David R. Klein; Verlag: John Wiley & Sons Inc; ISBN-10: 0470198699, ISBN-13: 978-0470198698. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Prerequisites / Notice | The course consists of lectures (36 hours) and problem-solving lessons (20 hours, groups of ca. 25 people). In addition, online exercises are available in the e-learning environment Moodle (Course OC I). | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| 551-0125-00L | Fundamentals of Biology I: From Molecules to the Biochemistry of Cells | O | 6 credits | 5G | J. Vorholt-Zambelli, N. Ban, R. Glockshuber, K. Locher, J. Piel | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Abstract | The lecture provides an introduction to the basics of biochemistry and molecular biology as well as evolutionary principles. The focus is on bacteria and archaea under consideration of universal concepts. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Learning objective | Introduction to biochemistry, molecular biology and evolutionary principles | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Content | The lecture introduces biology as an interdisciplinary science. Links to physics and chemistry will manifest as biological processes that operate within the laws of thermodynamics and are rooted in elements, molecules and chemical reactions. The transition from geochemistry to biochemistry is discussed and considered in relation to the origin of life. Evolutionary principles are introduced and resulting processes are used as a guiding principle. Unifying concepts in biology are presented, including the structure and function of cellular macromolecules and the ways in which hereditary information is encoded, decoded and replicated. Central principles of universal energy conversion are looked at, starting from redox processes and focusing on bacteria and archaea. Finally, biological processes are put into an ecosystems perspective. The lecture is divided into different sections: 1. Geochemical perspectives on Earth and introduction to evolution 2. Building blocks of life 3. Macromolecules: Proteins 4. Membranes and transport across the plasma membrane 5. Universal mechanisms of inheritance, transcription and translation 6. Reaction Kinetics, binding equilibria and enzymatic catalysis 7. Essentials of Catabolism 8. Essentials of Anabolism 9. Metabolism and biogeochemical cycling of elements | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Lecture notes | The newly conceived lecture is supported by scripts. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Literature | The lecture is supported by scripts. The lecture contains elements of "Brock Biology of Microorganisms", Madigan et al. 15th edition, Pearson und "Biochemistry" (Stryer), Berg et al. 9th edition, Macmillan international. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| First Year Examination Block 2 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Number | Title | Type | ECTS | Hours | Lecturers | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| 535-0001-00L | Introduction to Pharmaceutical Sciences I | O | 2 credits | 2V | J. Hall, K.‑H. Altmann, M. Detmar, C. Halin Winter, J.‑C. Leroux, U. Quitterer, J. Scheuermann, R. Schibli, H. U. Zeilhofer | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Abstract | First identification with Pharmaceutical Sciences; motivation for profiling in the Natural Sciences, which are focused on within the first two years as a preparation for the specialized studies; sensitization for the duties and the responsibilities of a person with a federal diploma in Pharmacy; information about job opportunities. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Learning objective | First identification with Pharmaceutical Sciences; motivation for profiling in the Natural Sciences as a preparation for the specialized studies; sensitization for the duties and the responsibilities of a person with a federal diploma in Pharmacy; information about job opportunities. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Content | Introduction to Pharmaceutical Sciences by selected milestones of research and development. Overview on research activities at the Institute of Pharmaceutical Sciences that is focussed on drug delivery and development (from concepts to prototypes). Sensitization for communication skills and information management. Demonstration of job opportunities in community pharmacies, in the hospital, in industry, and in the public sector by experts in the different fields. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Lecture notes | Handouts for individual lectures. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Prerequisites / Notice | Interactive teaching | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| 401-0291-00L | Mathematics I | O | 6 credits | 4V + 2U | A. Caspar | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Abstract | Mathematics I/II is an introduction to one- and multidimensional calculus and linear algebra emphasizing on applications. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Learning objective | Students understand mathematics as a language for modeling and as a tool for solving practical problems in natural sciences. Students can analyze models, describe solutions qualitatively or calculate them explicitly if need be. They can solve examples as well as their practical applications manually and using computer algebra systems. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Content | ## Eindimensionale diskrete Entwicklungen ## - linear, exponentiell, begrenzt, logistisch - Fixpunkte, diskrete Veränderungsrate - Folgen und Grenzwerte ## Funktionen in einer Variablen ## - Reproduktion, Fixpunkte - Periodizität - Stetigkeit ## Differentialrechnung (I) ## - Veränderungsrate/-geschwindigkeit - Differentialquotient und Ableitungsfunktion - Anwendungen der Ableitungsfunktion ## Integralrechnung (I) ## - Stammfunktionen - Integrationstechniken ## Gewöhnliche Differentialgleichungen (I) ## - Qualitative Beschreibung an Beispielen: Beschränkt, Logistisch, Gompertz - Stationäre Lösungen - Lineare DGL 1. Ordnung - Trennung der Variablen ## Lineare Algebra ## - Erste Arithmetische Aspekte - Matrizenrechnung - Eigenwerte / -vektoren - Quadratische LGS und Determinante | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Lecture notes | In Ergänzung zu den Vorlesungskapiteln der Lehrveranstaltungen fassen wir wichtige Sachverhalte, Formeln und weitere Ausführungen jeweils in einem Vademecum zusammen. Dabei gilt: * Die Skripte ersetzen nicht die Vorlesung und/oder die Übungen! * Ohne den Besuch der Lehrveranstaltungen verlieren die Ausführungen ihren Mehrwert. * Details entwickeln wir in den Vorlesungen und den Übungen, um die hier bestehenden Lücken zu schliessen. * Prüfungsrelevant ist, was wir in der Vorlesung und in den Übungen behandeln. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Literature | Siehe auch Lernmaterial > Literatur **Th. Wihler** Mathematik für Naturwissenschaften, 2 Bände: Einführung in die Analysis, Einführung in die Lineare Algebra; Haupt-Verlag Bern, UTB. **H. H. Storrer** Einführung in die mathematische Behandlung der Naturwissenschaften I; Birkhäuser. Via ETHZ-Bibliothek: https://link.springer.com/book/10.1007/978-3-0348-8598-0 **Ch. Blatter** Lineare Algebra; VDF auch als [pdf](<https://people.math.ethz.ch/~blatter/linalg.pdf>) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Prerequisites / Notice | ## Übungen und Prüfungen ## + Die Übungsaufgaben (inkl. Multiple-Choice) sind ein wichtiger Bestandteil der Lehrveranstaltung. + Es wird erwartet, dass Sie mindestens 75 % der wöchentlichen Serien bearbeiten und zur Korrektur einreichen. + Der Prüfungsstoff ist eine Auswahl von Themen aus Vorlesung und Übungen. Für eine erfolgreiche Prüfung ist die konzentrierte Bearbeitung der Aufgaben unerlässlich. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| 402-0073-00L | Physics I | O | 3 credits | 2V + 2U | T. M. Ihn | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Abstract | Introduction to the concepts and tools in physics with the help of demonstration experiments: mechanics and elements of quantum mechanics | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Learning objective | Students know and understand the basic ideas of the scientific description of nature. They understand the fundamental concepts and laws of mechanics and they are able to apply them in practical problems. They know the concepts of quantization and quantum numbers. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Content | 1. Description of Motion 2. The laws of Newton 3. Work and energy 4. Collision problems 5. Wave properties of particles 6. The atomic structure of matter | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Lecture notes | T. Ihn: Physics for Students in Biology and Pharmazeutical Sciences (unpublished lecture notes) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Literature | The lecture contains elements of: Paul A. Tipler and Gene P. Mosca, "Physik für Wissenschaftler und Ingenieure", Springer Spektrum. Feynman, Leighton, Sands, "The Feynman Lectures on Physics", Volume I (http://www.feynmanlectures.caltech.edu/) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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